|
1
|
Hu F, Liu C, Liu H, Xie L and Yu L:
Ataxia-telangiectasia mutated (ATM) protein signaling participates
in development of pulmonary arterial hypertension in rats. Med Sci
Monit. 23:4391–4400. 2017.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Goldberg AB, Mazur W and Kalra DK:
Pulmonary hypertension: Diagnosis, imaging techniques, and novel
therapies. Cardiovasc Diagn Ther. 7:405–417. 2017.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Hansmann G: Pulmonary hypertension in
infants, children, and young adults. J Am Coll Cardiol.
69:2551–2569. 2017.PubMed/NCBI View Article : Google Scholar
|
|
4
|
McClenaghan C, Woo KV and Nichols CG:
Pulmonary hypertension and ATP-sensitive potassium channels.
Hypertension. 74:14–22. 2019.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Elia D, Caminati A, Zompatori M, Cassandro
R, Lonati C, Luisi F, Pelosi G, Provencher S and Harari S:
Pulmonary hypertension and chronic lung disease: Where are we
headed? Eur Respir Rev. 28(31636088)2019.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Singh I, Oliveira RKF, Naeije R, Rahaghi
FN, Oldham WM, Systrom DM and Waxman AB: Pulmonary vascular
distensibility and early pulmonary vascular remodeling in pulmonary
hypertension. Chest. 156:724–732. 2019.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Ye J, Xu M, Tian X, Cai S and Zeng S:
Research advances in the detection of miRNA. J Pharm Anal.
9:217–226. 2019.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Lin S and Gregory RI: MicroRNA biogenesis
pathways in cancer. Nat Rev Cancer. 15:321–333. 2015.PubMed/NCBI View
Article : Google Scholar
|
|
9
|
Wang S, Cao W, Gao S, Nie X, Zheng X, Xing
Y, Chen Y, Bao H and Zhu D: TUG1 Regulates Pulmonary Arterial
Smooth Muscle Cell Proliferation in Pulmonary Arterial
Hypertension. Can J Cardiol. 35:1534–1545. 2019.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Wang Y, Pandey RN, York AJ, Mallela J,
Nichols WC, Hu YC, Molkentin JD, Wikenheiser-Brokamp KA and Hegde
RS: The EYA3 tyrosine phosphatase activity promotes pulmonary
vascular remodeling in pulmonary arterial hypertension. Nat Commun.
10(4143)2019.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Ruffenach G, Umar S, Vaillancourt M, Hong
J, Cao N, Sarji S, Moazeni S, Cunningham CM, Ardehali A, Reddy ST,
et al: Histological hallmarks and role of Slug/PIP axis in
pulmonary hypertension secondary to pulmonary fibrosis. EMBO Mol
Med. 11(e10061)2019.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Zheng Y, Lu X, Xu L, Chen Z, Li Q and Yuan
J: MicroRNA-675 promotes glioma cell proliferation and motility by
negatively regulating retinoblastoma 1. Hum Pathol. 69:63–71.
2017.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Cheleschi S, Tenti S, Mondanelli N,
Corallo C, Barbarino M, Giannotti S, Gallo I, Giordano A and
Fioravanti A: MicroRNA-34a and MicroRNA-181a mediate
visfatin-induced apoptosis and oxidative stress via NF-κB pathway
in human osteoarthritic chondrocytes. Cells. 8(874)2019.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Wang H, Tan Z, Hu H, Liu H, Wu T, Zheng C,
Wang X, Luo Z, Wang J, Liu S, et al: MicroRNA-21 promotes breast
cancer proliferation and metastasis by targeting LZTFL1. BMC
Cancer. 19(738)2019.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Liu T, Zou XZ, Huang N, Ge XY, Yao MZ, Liu
H, Zhang Z and Hu CP: Down-regulation of miR-204 attenuates
endothelial-mesenchymal transition by enhancing autophagy in
hypoxia-induced pulmonary hypertension. Eur J Pharmacol.
863(172673)2019.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Babicheva A, Ayon RJ, Zhao T, Ek Vitorin
JF, Pohl NM, Yamamura A, Yamamura H, Quinton BA, Ba M, Wu L, et al:
MicroRNA-mediated downregulation of K+ channels in
pulmonary arterial hypertension. Am J Physiol Lung Cell Mol
Physiol. 318:L10–L26. 2020.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Δ Δ C(T)) Method. Methods. 25:402–408. 2001.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Yin Y, Wu X, Yang Z, Zhao J, Wang X, Zhang
Q, Yuan M, Xie L, Liu H and He Q: The potential efficacy of
R8-modified paclitaxel-loaded liposomes on pulmonary arterial
hypertension. Pharm Res. 30:2050–2062. 2013.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Liu YF, Spinelli A, Sun LY, Jiang M,
Singer DV, Ginnan R, Saddouk FZ, Van Riper D and Singer HA:
MicroRNA-30 inhibits neointimal hyperplasia by targeting
Ca(2+)/calmodulin-dependent protein kinase IIδ (CaMKIIδ). Sci Rep.
6(26166)2016.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Morris HE, Neves KB, Montezano AC, MacLean
MR and Touyz RM: Notch3 signalling and vascular remodelling in
pulmonary arterial hypertension. Clin Sci (Lond). 133:2481–2498.
2019.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Li L, Zhu X, Shou T, Yang L, Cheng X, Wang
J, Deng L and Zheng Y: MicroRNA-28 promotes cell proliferation and
invasion in gastric cancer via the PTEN/PI3K/AKT signalling
pathway. Mol Med Rep. 17:4003–4010. 2018.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Yang Z, Xu J, Zhu R and Liu L:
Down-regulation of miRNA-128 contributes to neuropathic pain
following spinal cord injury via activation of P38. Med Sci Monit.
23:405–411. 2017.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Mundalil Vasu M, Anitha A, Thanseem I,
Suzuki K, Yamada K, Takahashi T, Wakuda T, Iwata K, Tsujii M,
Sugiyama T and Mori N: Serum microRNA profiles in children with
autism. Mol Autism. 5(40)2014.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Zhang K, Wu X, Wang J, Lopez J, Zhou W,
Yang L, Wang SE, Raz DJ and Kim JY: Circulating miRNA profile in
esophageal adenocarcinoma. Am J Cancer Res. 6:2713–2721.
2016.PubMed/NCBI
|
|
25
|
Yang M, Zhai X, Ge T, Yang C and Lou G:
miR-181a-5p Promotes Proliferation and Invasion and Inhibits
Apoptosis of Cervical Cancer Cells via Regulating Inositol
Polyphosphate-5-Phosphatase A (INPP5A). Oncol Res. 26:703–712.
2018.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Liu Z, Sun F, Hong Y, Liu Y, Fen M, Yin K,
Ge X, Wang F, Chen X and Guan W: MEG2 is regulated by miR-181a-5p
and functions as a tumour suppressor gene to suppress the
proliferation and migration of gastric cancer cells. Mol Cancer.
16(133)2017.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Li Q, Li Z, Wei S, Wang W, Chen Z, Zhang
L, Chen L, Li B, Sun G, Xu J, et al: Overexpression of miR-584-5p
inhibits proliferation and induces apoptosis by targeting WW
domain-containing E3 ubiquitin protein ligase 1 in gastric cancer.
J Exp Clin Cancer Res. 36(59)2017.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Liu J and Li SM: MiR-484 suppressed
proliferation, migration, invasion and induced apoptosis of gastric
cancer via targeting CCL-18. Int J Exp Pathol. 101:203–214.
2020.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Wu J, He Y, Luo Y, Zhang L, Lin H, Liu X,
Liu B, Liang C, Zhou Y and Zhou J: miR-145-5p inhibits
proliferation and inflammatory responses of RMC through regulating
AKT/GSK pathway by targeting CXCL16. J Cell Physiol. 233:3648–3659.
2018.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Ma Q, Wang Y, Zhang H and Wang F: miR-1290
contributes to colorectal cancer cell proliferation by targeting
INPP4B. Oncol Res. 26:1167–1174. 2018.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Armstrong DA, Nymon AB, Ringelberg CS,
Lesseur C, Hazlett HF, Howard L, Marsit CJ and Ashare A: Pulmonary
microRNA profiling: implications in upper lobe predominant lung
disease. Clin Epigenetics. 9(56)2017.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Nakamura A, Rampersaud YR, Sharma A, Lewis
SJ, Wu B, Datta P, Sundararajan K, Endisha H, Rossomacha E, Rockel
JS, et al: Identification of microRNA-181a-5p and microRNA-4454 as
mediators of facet cartilage degeneration. JCI Insight.
1(e86820)2016.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Chen F, Yang J, Li Y and Wang H:
Circulating microRNAs as novel biomarkers for heart failure.
Hellenic J Cardiol. 59:209–214. 2018.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Wang A, Kwee LC, Grass E, Neely ML,
Gregory SG, Fox KAA, Armstrong PW, White HD, Ohman EM, Roe MT, et
al: Whole blood sequencing reveals circulating microRNA
associations with high-risk traits in non-ST-segment elevation
acute coronary syndrome. Atherosclerosis. 261:19–25.
2017.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Liang L, Zeng JH, Wang JY, He RQ, Ma J,
Chen G, Cai XY and Hu XH: Down-regulation of miR-26a-5p in
hepatocellular carcinoma: A qRT-PCR and bioinformatics study.
Pathol Res Pract. 213:1494–1509. 2017.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Zhao F, Qu Y, Zhu J, Zhang L, Huang L, Liu
H, Li S and Mu D: miR-30d-5p plays an important role in autophagy
and apoptosis in developing rat brains after hypoxic-ischemic
injury. J Neuropathol Exp Neurol. 76:709–719. 2017.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Song Y, Song C and Yang S:
Tumor-Suppressive Function of miR-30d-5p in Prostate Cancer Cell
Proliferation and Migration by Targeting NT5E. Cancer Biother
Radiopharm. 33:203–211. 2018.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Jia K, Shi P, Han X, Chen T, Tang H and
Wang J: Diagnostic value of miR-30d-5p and miR-125b-5p in acute
myocardial infarction. Mol Med Rep. 14:184–194. 2016.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Li WF, Dai H, Ou Q, Zuo GQ and Liu CA:
Overexpression of microRNA-30a-5p inhibits liver cancer cell
proliferation and induces apoptosis by targeting MTDH/PTEN/AKT
pathway. Tumour Biol. 37:5885–5895. 2016.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Wang C, Cai L, Liu J, Wang G, Li H, Wang
X, Xu W, Ren M, Feng L, Liu P, et al: MicroRNA-30a-5p inhibits the
growth of renal cell carcinoma by modulating GRP78 expression. Cell
Physiol Biochem. 43:2405–2419. 2017.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Liu W, Li H, Wang Y, Zhao X, Guo Y, Jin J
and Chi R: miR-30b-5p functions as a tumor suppressor in cell
proliferation, metastasis and epithelial-to-mesenchymal transition
by targeting G-protein subunit α-13 in renal cell carcinoma. Gene.
626:275–281. 2017.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Qi B, Wang Y, Chen ZJ, Li XN, Qi Y, Yang
Y, Cui GH, Guo HZ, Li WH and Zhao S: Down-regulation of
miR-30a-3p/5p promotes esophageal squamous cell carcinoma cell
proliferation by activating the Wnt signaling pathway. World J
Gastroenterol. 23:7965–7977. 2017.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Ceolotto G, Giannella A, Albiero M,
Kuppusamy M, Radu C, Simioni P, Garlaschelli K, Baragetti A,
Catapano AL, Iori E, et al: miR-30c-5p regulates
macrophage-mediated inflammation and pro-atherosclerosis pathways.
Cardiovasc Res. 113:1627–1638. 2017.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Cao JM, Li GZ, Han M, Xu HL and Huang KM:
miR-30c-5p suppresses migration, invasion and epithelial to
mesenchymal transition of gastric cancer via targeting MTA1. Biomed
Pharmacother. 93:554–560. 2017.PubMed/NCBI View Article : Google Scholar
|
|
45
|
Xu G, Cai J, Wang L, Jiang L, Huang J, Hu
R and Ding F: MicroRNA-30e-5p suppresses non-small cell lung cancer
tumorigenesis by regulating USP22-mediated Sirt1/JAK/STAT3
signaling. Exp Cell Res. 362:268–278. 2018.PubMed/NCBI View Article : Google Scholar
|
|
46
|
Qin X, Li C, Guo T, Chen J, Wang HT, Wang
YT, Xiao YS, Li J, Liu P, Liu ZS, et al: Upregulation of DARS2 by
HBV promotes hepatocarcinogenesis through the miR-30e-5p/MAPK/NFAT5
pathway. J Exp Clin Cancer Res. 36(148)2017.PubMed/NCBI View Article : Google Scholar
|
|
47
|
Wang K, Chen M and Wu W: Analysis of
microRNA (miRNA) expression profiles reveals 11 key biomarkers
associated with non-small cell lung cancer. World J Surg Oncol.
15(175)2017.PubMed/NCBI View Article : Google Scholar
|
|
48
|
Coskun E, Ercin M and Gezginci-Oktayoglu
S: The role of epigenetic regulation and pluripotency-related
microRNAs in differentiation of pancreatic stem cells to beta
cells. J Cell Biochem. 119:455–467. 2018.PubMed/NCBI View Article : Google Scholar
|
|
49
|
Shukla K, Sharma AK, Ward A, Will R,
Hielscher T, Balwierz A, Breunig C, Münstermann E, König R,
Keklikoglou I, et al: MicroRNA-30c-2-3p negatively regulates NF-κB
signaling and cell cycle progression through downregulation of
TRADD and CCNE1 in breast cancer. Mol Oncol. 9:1106–1119.
2015.PubMed/NCBI View Article : Google Scholar
|
|
50
|
Mathew LK, Lee SS, Skuli N, Rao S, Keith
B, Nathanson KL, Lal P and Simon MC: Restricted expression of
miR-30c-2-3p and miR-30a-3p in clear cell renal cell carcinomas
enhances HIF2α activity. Cancer Discov. 4:53–60. 2014.PubMed/NCBI View Article : Google Scholar
|
|
51
|
Jacquin S, Rincheval V, Mignotte B,
Richard S, Humbert M, Mercier O, Londoño-Vallejo A, Fadel E and
Eddahibi S: Inactivation of p53 is sufficient to induce development
of pulmonary hypertension in rats. PLoS One.
10(e0131940)2015.PubMed/NCBI View Article : Google Scholar
|
|
52
|
Gao L, He RQ, Wu HY, Zhang TT, Liang HW,
Ye ZH, Li ZY, Xie TT, Shi Q, Ma J, et al: Expression Signature and
Role of miR-30d-5p in Non-Small Cell Lung Cancer: A comprehensive
study based on in silico analysis of public databases and in vitro
experiments. Cell Physiol Biochem. 50:1964–1987. 2018.PubMed/NCBI View Article : Google Scholar
|
|
53
|
Deng L, Blanco FJ, Stevens H, Lu R,
Caudrillier A, McBride M, McClure JD, Grant J, Thomas M, Frid M, et
al: MicroRNA-143 activation regulates smooth muscle and endothelial
cell crosstalk in pulmonary arterial hypertension. Circ Res.
117:870–883. 2015.PubMed/NCBI View Article : Google Scholar
|
|
54
|
Caruso P, Dunmore BJ, Schlosser K, Schoors
S, Dos Santos C, Perez-Iratxeta C, Lavoie JR, Zhang H, Long L,
Flockton AR, et al: Identification of MicroRNA-124 as a major
regulator of enhanced endothelial cell glycolysis in pulmonary
arterial hypertension via PTBP1 (polypyrimidine tract binding
protein) and pyruvate kinase M2. Circulation. 136:2451–2467.
2017.PubMed/NCBI View Article : Google Scholar
|
|
55
|
Cai Z, Li J, Zhuang Q, Zhang X, Yuan A,
Shen L, Kang K, Qu B, Tang Y, Pu J, et al: miR-125a-5p ameliorates
monocrotaline-induced pulmonary arterial hypertension by targeting
the TGF-β1 and IL-6/STAT3 signaling pathways. Exp Mol Med. 50:1–11.
2018.PubMed/NCBI View Article : Google Scholar
|
|
56
|
Thistlethwaite PA, Li X and Zhang X: Notch
signaling in pulmonary hypertension. Adv Exp Med Biol. 661:279–298.
2010.PubMed/NCBI View Article : Google Scholar
|
|
57
|
Skurikhin EG, Krupin VA, Pershina OV, Pan
ES, Ermolaeva LA, Pakhomova AV, Rybalkina OY, Ermakova NN,
Khmelevskaya ES, Vaizova OE, et al: Endothelial progenitor cells
and Notch-1 signaling as markers of alveolar endothelium
regeneration in pulmonary emphysema. Bull Exp Biol Med.
166:201–206. 2018.PubMed/NCBI View Article : Google Scholar
|
|
58
|
Guo ML, Kook YH, Shannon CE and Buch S:
Notch3/VEGF-A axis is involved in TAT-mediated proliferation of
pulmonary artery smooth muscle cells: Implications for
HIV-associated PAH. Cell Death Discov. 4(22)2018.PubMed/NCBI View Article : Google Scholar
|
