Open Access

Nasopharyngeal carcinoma: A new synthesis of literature data (Review)

  • Authors:
    • Daniela Jicman (Stan)
    • Elena Niculet
    • Mihaela Lungu
    • Cristian Onisor
    • Laura Rebegea
    • Doinita Vesa
    • Laura Bezman
    • Florin Ciprian Bujoreanu
    • Mihaela Ionela Sarbu
    • Raul Mihailov
    • Silvia Fotea
    • Alin Laurentiu Tatu
  • View Affiliations

  • Published online on: December 13, 2021     https://doi.org/10.3892/etm.2021.11059
  • Article Number: 136
  • Copyright: © Jicman (Stan) et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Nasopharyngeal carcinoma (NPC) is an epithelial tumor, which develops most frequently from the lateral pharyngeal recess and holds some complex epidemiological characteristics. Its unusual race and geographic distribution suggests that not only the environmental factors are a contributing factor to the development of this rare cancer type, but also the genetic traits play an important role, along with nitrosamine‑containing food consumption and Epstein‑Barr virus infection. The signs and symptoms which a patient can present and suffer from are various and include nasal, otic, neurological as well as general ones; the way this tumor manifests being dependent on the stage of the tumor. The therapeutic management applicable in NPC needs to be established according to the case of the patient and include radiotherapy, chemotherapy, surgery, immune therapy, targeted therapy or combined treatment. The main objective of the treatment is local and regional tumor control; relapse is an important factor for future development of distant metastases. New therapeutic concepts are always sought of, current research focusing on precision medicine, meaning systemic treatment with a personalized radiotherapy approach according to the characteristics of the tumor.
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February-2022
Volume 23 Issue 2

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Jicman (Stan) D, Niculet E, Lungu M, Onisor C, Rebegea L, Vesa D, Bezman L, Bujoreanu FC, Sarbu MI, Mihailov R, Mihailov R, et al: Nasopharyngeal carcinoma: A new synthesis of literature data (Review). Exp Ther Med 23: 136, 2022
APA
Jicman (Stan), D., Niculet, E., Lungu, M., Onisor, C., Rebegea, L., Vesa, D. ... Tatu, A.L. (2022). Nasopharyngeal carcinoma: A new synthesis of literature data (Review). Experimental and Therapeutic Medicine, 23, 136. https://doi.org/10.3892/etm.2021.11059
MLA
Jicman (Stan), D., Niculet, E., Lungu, M., Onisor, C., Rebegea, L., Vesa, D., Bezman, L., Bujoreanu, F. C., Sarbu, M. I., Mihailov, R., Fotea, S., Tatu, A. L."Nasopharyngeal carcinoma: A new synthesis of literature data (Review)". Experimental and Therapeutic Medicine 23.2 (2022): 136.
Chicago
Jicman (Stan), D., Niculet, E., Lungu, M., Onisor, C., Rebegea, L., Vesa, D., Bezman, L., Bujoreanu, F. C., Sarbu, M. I., Mihailov, R., Fotea, S., Tatu, A. L."Nasopharyngeal carcinoma: A new synthesis of literature data (Review)". Experimental and Therapeutic Medicine 23, no. 2 (2022): 136. https://doi.org/10.3892/etm.2021.11059