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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2022 Volume 23 Issue 2

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Impact Factor: 2.3

Article Open Access

CBL knockdown protects cardiomyocytes against hypoxia‑reoxygenation injury by downregulating GRB2 expression

Zhengbing Lv, Xiaojia Luo, Biying Hong, Qiran Ye, Jianxiong Liu, Yongmei Hu
Article Number: 188
Published online on: 03 January 2022

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Review

Systematic review of the role of indocyanine green near‑infrared fluorescence in safe laparoscopic cholecystectomy (Review)

Dragos Serban, Dumitru Cristinel Badiu, Dragos Davitoiu, Ciprian Tanasescu, Mihail Silviu Tudosie, Alexandru Dan Sabau, Ana Maria Dascalu, Corneliu Tudor, Simona Andreea Balasescu, Bogdan Socea, Daniel Ovidiu Costea, Anca Zgura, Andreea Cristina Costea, Laura Carina Tribus, Catalin Gabriel Smarandache
Article Number: 187
Published online on: 30 December 2021

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Case Report

Bacterial endocarditis masked by COVID‑19: A case report

Mircea Bajdechi, Nicoleta Dorina Vlad, Mirela Dumitrascu, Elena Mocanu, Irina Magdalena Dumitru, Roxana Carmen Cernat, Sorin Rugină
Article Number: 186
Published online on: 30 December 2021

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Review Open Access

Restless legs syndrome: An overview of pathophysiology, comorbidities and therapeutic approaches (Review)

Andrei Vlasie, Simona Corina Trifu, Cristiana Lupuleac, Bianca Kohn, Mihai Bogdan Cristea
Article Number: 185
Published online on: 30 December 2021

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Case Report

Portal vein reconstruction with interposition of cryopreserved aortic graft: A case report and literature review

Nicolae Bacalbasa, Irina Balescu, Camelia Diaconu, Bogdan Socea, Florentina Gherghiceanu, Ovidiu Stiru, Vladislav Brasoveanu
Article Number: 184
Published online on: 30 December 2021

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Article Open Access

p‑Coumaric acid suppresses reactive oxygen species‑induced senescence in nucleus pulposus cells

Kunkun Sheng, Yan Li, Zhan Wang, Kai Hang, Zhaoming Ye
Article Number: 183
Published online on: 30 December 2021

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Article Open Access

Hydroxysafflor yellow A attenuates oxidative stress injury‑induced apoptosis in the nucleus pulposus cell line and regulates extracellular matrix balance via CA XII

Shuo Yang, Wenbo Liao
Article Number: 182
Published online on: 30 December 2021

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Article Open Access

Benzoyl‑xanthone derivative induces apoptosis in MCF‑7 cells by binding TRAF6

Xuan Zhao, Limei Ren, Xiaoru Wang, Guangxin Han, Shuo Wang, Qingguo Yao, Yonghao Qi
Article Number: 181
Published online on: 30 December 2021

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Article Open Access

Electrochemical monitoring of bronchial inflammation in pediatric athletes: A prospective study

Radu Diaconu, Florentina Dumitrescu, Loredana Stoica, Carmen Diaconu, Mihaela-Amelia Dobrescu, Adina-Dorina Glodeanu, Mihaela Ionescu, Nikolaos Mavritsakis, Doru Stoica
Article Number: 180
Published online on: 28 December 2021

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Review Open Access

Metabolic comorbidities of psoriasis (Review)

Daciana Elena Branisteanu, Ruxandra Angela Pirvulescu, Alina Elena Spinu, Elena Andrese Porumb, Mihaela Cojocaru, Alin Codrut Nicolescu, Daniel Constantin Branisteanu, Catalina Ioana Branisteanu, Andreea Dimitriu, Anisia Iuliana Alexa, Mihaela Paula Toader
Article Number: 179
Published online on: 28 December 2021

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Review Open Access

New strategies of diagnostic and therapeutic approach to emergencies in the evolution of patients with diabetes mellitus (Review)

Maria Forțofoiu, Ionela Mihaela Vladu, Mircea-Cătălin Forțofoiu, Rodica Pădureanu, Diana Clenciu, Dumitru Rădulescu, Vlad Pădureanu
Article Number: 178
Published online on: 28 December 2021

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Case Report Open Access

Malignant mixed Müllerian tumor of the fallopian tube: Case report and literature review

Alexandra Lavinia Cozlea, Mihai Gheorghe, Szilard Leo Kiss, Anas Fandi, Mihai Stanca, Simona Mocan, Mihai Emil Căpîlna, Nicolae Bacalbașa, Andreea Anamaria Moldovan
Article Number: 177
Published online on: 28 December 2021

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Review

Lung neuroendocrine tumors: A systematic literature review (Review)

Cornel Savu, Alexandru Melinte, Camelia Diaconu, Ovidiu Stiru, Florentina  Gherghiceanu, Ștefan Dragoș Octavian Tudorica, Oana Clementina Dumitrașcu, Angelica Bratu, Irina Balescu, Nicolae Bacalbasa
Article Number: 176
Published online on: 28 December 2021

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Case Report Open Access

Therapeutic challenges of psoriasis in the HIV‑infected patient: A case report

Manuela Arbune, Anca-Adriana Arbune, Elena Niculet, Lucretia Anghel, Silvia Fotea, Alin Laurentiu Tatu
Article Number: 175
Published online on: 28 December 2021

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Review Open Access

Continuous glucose monitoring devices: A brief presentation (Review)

Doina Andrada Mihai, Diana Simona Stefan, Daniela Stegaru, Georgiana Elena Bernea, Ileana Adela Vacaroiu, Toma Papacocea, Mircea Ovidiu Denis Lupușoru, Adriana Elena Nica, Ovidiu Stiru, Dorin Dragos, Octavian Gabriel Olaru
Article Number: 174
Published online on: 28 December 2021

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Case Report Open Access

Clinicopathological correlation of transient acantholytic dermatosis: A case report

Ilarie Brihan, Gyula László Fekete, Constanta Turda, Ovidiu Tica, Alina Cristiana Venter, Simona Ianosi, Carmen-Daniela Neagoe, Daciana Elena Branisteanu
Article Number: 173
Published online on: 28 December 2021

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Article Open Access

Effect of Src tyrosine kinase on a rat model of asthma

Min Wu, Jingping Yang, Tao Liu, Pengfei Xuan, Baoying Bu, Xiyuan Xu, Rina Wu
Article Number: 172
Published online on: 27 December 2021

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Article

Lectin‑type oxidized LDL receptor 1 modulates matrix metalloproteinase 2 production in peri‑implantitis

Qian Zhang, Tao Xu, Na Bai, Fei Tan, Hongmei Zhao, Jie Liu
Article Number: 171
Published online on: 27 December 2021

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Review Open Access

Fate of hematopoietic stem cells determined by Notch1 signaling (Review)

Yidong Ge, Jie Wang, Hui Zhang, Jinyun Li, Meng Ye, Xiaofeng Jin
Article Number: 170
Published online on: 27 December 2021

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Article Open Access

PRUNE2 inhibits progression of colorectal cancer in vitro and in vivo

Ting Li, Silin Huang, Wei Yan, Yu Zhang, Qiang Guo
Article Number: 169
Published online on: 27 December 2021

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Article Open Access

Gastrodin inhibits high glucose‑induced inflammation, oxidative stress and apoptosis in podocytes by activating the AMPK/Nrf2 signaling pathway

Luyan Huang, Minghai Shao, Yan Zhu
Article Number: 168
Published online on: 23 December 2021

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Article Open Access

Morphological and morphometric changes in the Purkinje cells of patients with essential tremor

Ioannis Mavroudis, Dimitrios Kazis, Foivos Petridis, Simela Chatzikonstantinou, Eleni Karantali, Samuel N. Njau, Vasiliki Costa, Alin Ciobica, Constantin Trus, Ioana Miruna Balmus, Stavros J. Baloyannis
Article Number: 167
Published online on: 23 December 2021

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Article Open Access

Complement regulation in ovine lymph nodes during early pregnancy

Leying Zhang, Lidong Cao, Pengfei Feng, Xu Han, Ling Yang
Article Number: 166
Published online on: 23 December 2021

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Article Open Access

MicroRNA‑195‑5p inhibits the progression of hemangioma via targeting SKI Retraction in /10.3892/etm.2024.12767

Bin Sun, Zhi Huang, Hua Yang, Xuya Zhao
Article Number: 165
Published online on: 22 December 2021

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Article Open Access

Roles of ERRα and TGF‑β signaling in stemness enhancement induced by 1 µM bisphenol A exposure via human neural stem cells

Panpan Dong, Ganghui Ye, Xinzhuo Tu, Ying Luo, Weitong Cui, Yuxin Ma, Lei Wei, Xuewen Tian, Qinglu Wang
Article Number: 164
Published online on: 22 December 2021

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Article Open Access

Changes of farnesoid X receptor and Takeda G‑protein coupled receptor 5 following biliary tract external drainage in hemorrhagic shock

Lu Wang, Huai-Wu He, Xiang Zhou, Yun Long
Article Number: 163
Published online on: 21 December 2021

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Article Open Access

Potential biomarkers of acute myocardial infarction based on co‑expression network analysis

Zhaohui Hu, Ruhui Liu, Hairong Hu, Xiangjun Ding, Yuyao Ji, Guiyuan Li, Yiping Wang, Shengquan Xie, Xiaohong Liu, Zhiwen Ding
Article Number: 162
Published online on: 21 December 2021

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Article Open Access

P2X7R antagonist protects against renal injury in mice with adriamycin nephropathy

Yanji Zhu, Min Liu, Wenlong Xun, Keliang Li, Xiangji Niu
Article Number: 161
Published online on: 21 December 2021

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Article Open Access

Unraveling the molecular mechanisms of hyperlipidemia using integrated lncRNA and mRNA microarray data

Bianling Xu, Nan Wang, Xuegong Xu, Yongmin Cai
Article Number: 160
Published online on: 20 December 2021

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Article

Diagnostic approach and treatment specificity in patients with focal lesions of the biliopancreatic area complicated by mechanical jaundice

Petro Muraviov, Boris Zaporozhchenko, Igor Borodaev, V.V. Kolodiy, Anatoliy Gorbunov, E.P. Kirpichnikova, Nicolae Bacalbasa, Irina Balescu, Makrem Harhouri
Article Number: 159
Published online on: 17 December 2021

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Article Open Access

Intestinal ischemia‑reperfusion induces the release of IL‑17A to regulate cell inflammation, apoptosis and barrier damage

Li Xiao, Wan-Hua Zhang, Yin Huang, Peng Huang
Article Number: 158
Published online on: 17 December 2021

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Article Open Access

APPL1 ameliorates myocardial ischemia‑reperfusion injury by regulating the AMPK signaling pathway

Yunguang Cen, Wei Liao, Taihao Wang, Daimin Zhang
Article Number: 157
Published online on: 17 December 2021

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Article Open Access

Analysis of long‑term anatomic results of radical mastoidectomy

Horia Mocanu, Adela-Ioana Mocanu, Gabriella Coadă, Alexandru Bonciu, Mihai-Adrian Schipor, Marian Rădulescu
Article Number: 156
Published online on: 17 December 2021

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Review

Signal transduction mechanism of exosomes in diabetic complications (Review)

Xueting Li, Shuo Shi, Dehuai Jing, Xinjian Li, Bin Zhang, Qingli Bie
Article Number: 155
Published online on: 17 December 2021

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Article Open Access

KDM2B overexpression prevents myocardial ischemia‑reperfusion injury in rats through regulating inflammatory response via the TLR4/NF‑κB p65 axis

Zijie Wei, Lihua Luo, Shuo Hu, Rongcheng Tian, Ziyou Liu
Article Number: 154
Published online on: 17 December 2021

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Review Open Access

Artificial intelligence applications and robotic systems in Parkinson's disease (Review)

Lacramioara Perju‑Dumbrava, Maria Barsan, Daniel Corneliu Leucuta, Luminita C. Popa, Cristina Pop, Nicoleta Tohanean, Stefan L. Popa
Article Number: 153
Published online on: 17 December 2021

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Review Open Access

Cardiovascular comorbidities in psoriasis (Review)

Daciana Elena Branisteanu, Alin Codrut Nicolescu, Daniel Constantin Branisteanu, Catalina Ioana Branisteanu, Andreea Corina Dragoi, Camelia Margareta Bogdanici, Mihaela Paula Toader, Andreea Lorena Tucaliuc, Andreea Dimitriu, Doru Daogaru, Ruxandra Angela Pirvulescu, Elena Andrese Porumb
Article Number: 152
Published online on: 17 December 2021

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Review Open Access

Adult female acne: Clinical and therapeutic particularities (Review)

Daciana Elena Branisteanu, Mihaela Paula Toader, Elena Andrese Porumb, Ionela Lacramioara Serban, Alin Constantin Pinzariu, Catalina Ioana Branisteanu, Anastasia Vicovan, Andreea Dimitriu, Isabela-Alexandra Fartusnic, Daniel Boda, Daniel Constantin Branisteanu, Ilarie Brihan, Alin Codrut Nicolescu
Article Number: 151
Published online on: 16 December 2021

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Article

Success rate of methotrexate in the conservative treatment of tubal ectopic pregnancies

Corina Grigoriu, Roxana Elena Bohiltea, Bianca Margareta Mihai, Corina Aurelia Zugravu, Florentina Furtunescu, Tiberiu Augustin Georgescu, Diana Ionela Munteanu
Article Number: 150
Published online on: 16 December 2021

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Article

Mucosal gene expression profile of stricturing Crohn's disease: A preliminary study

Cristian George Tieranu, Andrei Ovidiu Olteanu, Carmen Monica Preda, Nicolae Bacalbasa, Elena Milanesi, Maria Dobre, Ioana Tieranu, Teodora Ecaterina Manuc, Artsiom Klimko, Gabriel Becheanu, Elena Mirela Ionescu
Article Number: 149
Published online on: 16 December 2021

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Article Open Access

Silencing CoREST inhibits the viability and migration of fibroblast‑like synoviocytes in TNF‑α‑induced rheumatoid arthritis

Ziliang Yu, Feihu Chen, Hao Liu, Jianbo Fan, Xiaomin Ding, Xinhui Zhu, Shengyu Cui, Hong Yi, Xiaogang Zhou, Yalong Hu, Wei Liu
Article Number: 148
Published online on: 15 December 2021

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Article Open Access

Role of cyclin‑dependent kinase 5 in early brain injury following experimental subarachnoid hemorrhage

Yu Ding, Liexiang Zhang, Wei Zhou, Hai Lu, Xingde Gao, Jian Li, Jingde Liu, Xiaowang Niu, Jing Zheng
Article Number: 147
Published online on: 15 December 2021

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Article Open Access

Costal cartilage overgrowth does not induce pectus‑like deformation in the chest wall of a rat model

Vlad Laurentiu David, Maria Corina Stanciulescu, Florin George Horhat, Abhinav Sharma, Nilima Rajpal Kundnani, Bogdan Ciornei, Ramona Florina Stroescu, Marius Calin Popoiu, Eugen Sorin Boia
Article Number: 146
Published online on: 15 December 2021

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Review Open Access

Congenitally missing second permanent molars in non‑syndromic patients (Review)

Alexandru-Titus Farcașiu, Rodica Luca, Andreea Didilescu, Ioana-Andreea Stanciu, Catalina Farcasiu, Arina Vinereanu, Aneta Munteanu
Article Number: 145
Published online on: 15 December 2021

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Article Open Access

Therapeutic effect and mechanism of 4‑phenyl butyric acid on renal ischemia‑reperfusion injury in mice

Xinlei Wang, Yang Zhang, Kun Wuyun, Haixia Gong
Article Number: 144
Published online on: 15 December 2021

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Article Open Access

Galectin‑1 alleviates myocardial ischemia‑reperfusion injury by reducing the inflammation and apoptosis of cardiomyocytes

Dengke Ou, Dan Ni, Rong Li, Xiaobo Jiang, Xiaoxiao Chen, Hongfei Li
Article Number: 143
Published online on: 15 December 2021

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Article Open Access

MicroRNA‑126 and VEGF enhance the function of endothelial progenitor cells in acute myocardial infarction

Ying Zhang, Yi Xu, Ke Zhou, Guoying Kao, Jun Xiao
Article Number: 142
Published online on: 14 December 2021

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Article

Synergistic effect of Bruton's tyrosine kinase and TNF‑α in the regulation of rheumatoid arthritis and underlying mechanisms

Jinwan Du
Article Number: 141
Published online on: 14 December 2021

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Article

miR‑340‑5p inhibits pancreatic acinar cell inflammation and apoptosis via targeted inhibition of HMGB1

Yazhou Gao, Liming Wang, Zequn Niu, Hui Feng, Jie Liu, Jiangli Sun, Yanxia Gao, Longfei Pan
Article Number: 140
Published online on: 14 December 2021

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Article Open Access

Transplantation of IL‑1β siRNA‑modified bone marrow mesenchymal stem cells ameliorates type II collagen‑induced rheumatoid arthritis in rats

Shifeng Pan, Xuan Dong, Yan Wang, Tiansheng Zhou, Yuting Liu, An Zhou, Hua Xing
Article Number: 139
Published online on: 14 December 2021

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Article Open Access

Synchronous biliary gallstones and colorectal cancer: A single center analysis

Narcis Octavian Zarnescu, Eugenia Claudia Zarnescu, Ioana Dumitrascu, Alexandru Chirca, Nicoleta Sanda, Andreea Iliesiu, Radu Costea
Article Number: 138
Published online on: 13 December 2021

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Review Open Access

Diagnostic methods for the etiological assessment of infectious corneal pathology (Review)

Mihail Zemba, Otilia-Maria Dumitrescu, Andreea-Elena Dimirache, Daniel Constantin Branisteanu, Florian Balta, Marian Burcea, Andreea Dana Moraru, Sinziana Gradinaru
Article Number: 137
Published online on: 13 December 2021

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Review Open Access

Nasopharyngeal carcinoma: A new synthesis of literature data (Review)

Daniela Jicman (Stan), Elena Niculet, Mihaela Lungu, Cristian Onisor, Laura Rebegea, Doinita Vesa, Laura Bezman, Florin Ciprian Bujoreanu, Mihaela Ionela Sarbu, Raul Mihailov, Silvia Fotea, Alin Laurentiu Tatu
Article Number: 136
Published online on: 13 December 2021

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Case Report Open Access

Orthopaedic manifestations of neurofibromatosis type 1: A case report

Florentina Năstase, Diana Sabina Radaschin, Elena Niculeț, Andrei Vlad Brădeanu, Mădălina Codruța Verenca, Aurel Nechita, Valentin Chioncel, Lawrence Chukwudi Nwabudike, Liliana Baroiu, Eduard Drima Polea, Silvia Fotea, Lucretia Anghel, Alexandru Nechifor, Alin Laurenţiu Tatu
Article Number: 135
Published online on: 13 December 2021

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Review Open Access

Old and new therapeutic strategies in systemic sclerosis (Review)

Carmen Bobeica, Elena Niculet, Alin Laurentiu Tatu, Mihaela Craescu, Dan Vata, Laura Statescu, Alina Viorica Iancu, Carmina Liana Musat, Miruna Luminita Draganescu, Cristian Onisor, Mihaela Lungu, Silvia Fotea, Aurel Nechita, Bogdan Ioan Stefanescu, Laura Gheuca‑Solovastru
Article Number: 134
Published online on: 13 December 2021

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Correction Open Access

[Corrigendum] Baicalin promotes the viability of Schwann cells in vitro by regulating neurotrophic factors

Wenpu Zuo, Huayu Wu, Kun Zhang, Peizhen Lv, Fuben Xu, Weizhe Jiang, Li Zheng, Jinmin Zhao
Article Number: 133
Published online on: 13 December 2021

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Article Open Access

Pitavastatin maintains MAPK7 expression and alleviates angiotensin II‑induced vascular endothelial cell inflammation and injury

Min Li, Xiaohua Liu
Article Number: 132
Published online on: 13 December 2021

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Article Open Access

Knockdown of long non‑coding RNA NEAT1 relieves inflammation of ulcerative colitis by regulating the miR‑603/FGF9 pathway

Fengdong Li, Hui Liu, Jinjin Fu, Li Fan, Shuangshuang Lu, Huahui Zhang, Zhanju Liu
Article Number: 131
Published online on: 10 December 2021

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VEGF mitigates bisphosphonate‑induced apoptosis and differentiation inhibition of MC3T3‑E1 cells

Yao Duan, Hejia Li, Xiaohong Dong, Zhaoli Geng, Xinyi Xu, Yi Liu
Article Number: 130
Published online on: 10 December 2021

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Review Open Access

Risk factors for fluctuations in corneal endothelial cell density (Review)

Renata Vaiciuliene, Neda Rylskyte, Gabija Baguzyte, Vytautas Jasinskas
Article Number: 129
Published online on: 10 December 2021

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CPNE3 interaction with RACK1 protects against myocardial ischemia/reperfusion injury

Xiaoqun Zhang, Xue Han, Yanan Zhang
Article Number: 128
Published online on: 10 December 2021

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miR‑27b attenuates dexamethasone‑inhibited proliferation and osteoblastic differentiation in MC3T3‑E1 cells by targeting PPARγ2

Huicheng Lv, Tieyi Yang, Aimin He, Mingbo Wang, Haisheng Jia, Min Ma, Siqin Li
Article Number: 127
Published online on: 10 December 2021

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Hydrogen‑rich saline alleviates early brain injury through inhibition of necroptosis and neuroinflammation via the ROS/HO‑1 signaling pathway after traumatic brain injury

Yun Hu, Xiaoyan Feng, Junhui Chen, Yan Wu, Liuyan Shen
Article Number: 126
Published online on: 09 December 2021

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Serous otitis media: Clinical and therapeutic considerations, including dexamethasone (C22H29FO5) intratympanic injection

Cristian Mârțu, Sebastian Cozma, Bogdan Cobzeanu, Doina Vesa, Corina Butnaru, Dragoș Bularda, Adeline Cumpătă, Luminița Rădulescu
Article Number: 125
Published online on: 07 December 2021

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Nursing procedures for advanced dementia: Traditional techniques versus autonomous robotic applications (Review)

Liliana David, Stefan L. Popa, Maria Barsan, Lucian Muresan, Abdulrahman Ismaiel, Luminita C. Popa, Lacramioara Perju‑Dumbrava, Mihaela Fadgyas Stanculete, Dan L. Dumitrascu
Article Number: 124
Published online on: 07 December 2021

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Research on demographic, clinical and paraclinical aspects in pregnant women infected with Toxoplasma gondii

Andrei Csep, Luminița Ligia Vaida, Bianca-Maria Negruțiu, Bianca Ioana Todor, Claudia Teodora Judea‑Pusta, Camelia Buhaș, Cristian Sava
Article Number: 123
Published online on: 07 December 2021

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Review

Benefits of crenotherapy in digestive tract pathology (Review)

Magdalena Dumitrescu, Madalina Gabriela Iliescu, Laura Mazilu, Sergiu Ioan Micu, Adrian Paul Suceveanu, Felix Voinea, Claudia Voinea, Anca Pantea Stoian, Andra-Iulia Suceveanu
Article Number: 122
Published online on: 07 December 2021

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Treatment of patients with Covid‑19 with a high dose of ulinastatin

Hai Huang, Ping-Fang Hu, Liang-Liang Sun, Yi-Bin Guo, Qiong Wang, Zhi-Min Liu, Ji-Zhong Yin, Pei-Mei Shi, Zong-Li Yuan, Wei-Fen Xie
Article Number: 121
Published online on: 07 December 2021

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Bazedoxifene activates the angiotensin II‑induced HUVEC hypertension model by targeting SIRT1

Qian Yu, Jin Zhao, Baotang Liu
Article Number: 120
Published online on: 07 December 2021

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Review Open Access

Role of heparinase in the gastrointestinal dysfunction of sepsis (Review)

Ting-Ting Chen, Jia-Jun Lv, Ling Chen, Yu-Wei Gao, Li-Ping Liu
Article Number: 119
Published online on: 06 December 2021

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RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1 Corrigendum in /10.3892/etm.2022.11255

Yajuan Huang, Yufeng Zou, Zhigang Jie
Article Number: 118
Published online on: 06 December 2021

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Cytomorphological study of thyroid carcinoma

Iuliana Mohorea, Dana Terzea, Daniela Mihalache, Bogdan Socea, Dragoş Şerban, Mihai Ceausu
Article Number: 117
Published online on: 06 December 2021

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Salvianolic acid B inhibits the progression of liver fibrosis in rats via modulation of the Hedgehog signaling pathway

Shanjun Tao, Renjie Duan, Tong Xu, Jiao Hong, Wenjie Gu, Aiqin Lin, Likai Lian, Haoyu Huang, Jiangtao Lu, Tiechen Li
Article Number: 116
Published online on: 06 December 2021

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Predictive value of using plasma long non‑coding RNAs ANRIL and HOXA11‑AS for in‑stent restenosis

Zhijiang Jin, Hongfeng Shen, Wei Cha, Haijiang Xia, Longbin Liu
Article Number: 115
Published online on: 06 December 2021

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Review

Tyrosine kinase inhibitors in breast cancer (Review)

George Iancu, Dragos Serban, Cristinel Dumitru Badiu, Ciprian Tanasescu, Mihai Silviu Tudosie, Corneliu Tudor, Daniel Ovidiu Costea, Anca Zgura, Raluca Iancu, Danut Vasile
Article Number: 114
Published online on: 03 December 2021

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Overview of the anatomical basis of the piriformis syndrome‑dissection with magnetic resonance correlation

Ofelia-Costina Goidescu, Mihaly Enyedi, Adrian-Daniel Tulin, Raluca Tulin, Ileana Adela Vacaroiu, Adriana Elena Nica, Dorin Dragos, Dorin Ionescu, Dragos Georgescu, Adrian Miron, Florin-Mihail Filipoiu
Article Number: 113
Published online on: 03 December 2021

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Morphometric study regarding ophthalmic and internal carotid arteries utilizing computed tomography angiography

Radu Andrei Baz, Sanda Jurja, Radu Ciuluvica, Cristian Scheau, Radu Baz
Article Number: 112
Published online on: 03 December 2021

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Heavy metal ion concentration in the amniotic fluid of preterm and term pregnancies from two cities with different industrial output

Radu Ionut Neamtu, Marius Craina, George Dahma, Alin Viorel Popescu, Adelina Geanina Erimescu, Ioana Citu, Amadeus Dobrescu, Florin George Horhat, Dan Dumitru Vulcanescu, Florin Gorun, Elena Silvia Bernad, Andrei Motoc, Ioan Cosmin Citu
Article Number: 111
Published online on: 03 December 2021

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March-2026 Volume 31 Issue 3

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Article Open Access

Effect of SGLT2 inhibitors on heart failure outcomes in patients with and without diabetes: A systematic review and meta‑analysis of randomized controlled trials

Duaa Abdullah Bafail, Noura Hamdi Alhalees
Article Number: 84
Published online on: 28 January 2026

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Exploring the protective mechanisms and therapeutic potential of carnosic acid against acute respiratory distress syndrome through molecular docking, molecular dynamics and experimental verification

Quan Li, Lili Ding, Haijun Sun, Weichao Ding, Mengmeng Wang, Zhaorui Sun, Congxue Ma
Article Number: 83
Published online on: 28 January 2026

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Review

Exploring the roots of schizophrenia: Current research and future directions (Review)

Shuang Lv, Chunxia Luo
Article Number: 82
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] miR‑146a‑5p protects against renal injury in MRL/lpr mice via improvement of the Treg/Th17 imbalance by targeting the TRAF6/NF‑κB axis

Jiajia Teng, Feng Yang, Xiaoling Li
Article Number: 81
Published online on: 28 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑24‑3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl‑2‑like protein 11

Huanxin Zhang, Shizhen Xue, Yi Feng, Jun Shen, Jixian Zhao
Article Number: 80
Published online on: 26 January 2026

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Efficacy and safety of unilateral biportal endoscopy vs. percutaneous endoscopic interlaminar approach in lumbar disc herniation: A meta‑analysis​

Yuhao Gao, Fangzheng He, Ji Wen, Shilei Qin, Pengfei Han, Yunfeng Xu
Article Number: 79
Published online on: 23 January 2026

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Case Report Open Access

Intralobar pulmonary sequestration coexisting with pulmonary cryptococcosis: A case report and literature review

Dan Cheng, Yue Wang, Jun Li, Dan Yu, Yunyun Wang, Jinbo Fan, Jiankun Wang, Liqun He
Article Number: 78
Published online on: 23 January 2026

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Tumor‑associated macrophages suppress estrogen receptor‑β expression in triple‑negative breast cancer through the PI3K/AKT pathway

Qiulei Zhang, Di Guo, Gaoran Xu, Rong Xie, Yuqing Deng, Peng Fu, Jinnan Wan
Article Number: 77
Published online on: 21 January 2026

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Development of a diagnostic model for esophageal achalasia assessed by esophageal high‑resolution manometry using artificial intelligence

Maiko Tabuchi, Yasuhiko Nakao, Hitomi Minami, Hiroko Inomata, Junya Shiota, Taro Akashi, Keiichi Hashiguchi, Moto Kitayama, Kayoko Matsushima, Naoyuki Yamaguchi, Yuko Akazawa, Hisamitsu Miyaaki
Article Number: 76
Published online on: 21 January 2026

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Case Report

Use of metagenomic next‑generation sequencing to diagnose Tropheryma whipplei infection‑related pneumonia: A case report

Yutu Luo, Haibing Ding, Jiahua Pan, Guangyang Xu
Article Number: 75
Published online on: 21 January 2026

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Effect of rivaroxaban on DNA damage in an ischemia-reperfusion model: Evaluation of 8‑OHdG levels

Ceren Sayarer, Abidin Cenk Erdal, Tuğra Gençpinar, Özlem Gürsoy Doruk, Tuncay Küme
Article Number: 74
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Hepatoprotective activity of chrysin is mediated through TNF‑α in chemically‑induced acute liver damage: An in vivo study and molecular modeling 

Anca Hermenean, Teodora Mariasiu, Inmaculada Navarro-González, Josefina Vegara-Meseguer, Eftimie Miuțescu, Sandipan Chakraborty, Horacio Pérez-Sánchez
Article Number: 73
Published online on: 21 January 2026

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Retraction Open Access

[Retracted] Gambogic acid suppresses colon cancer cell activity in vitro

Zailong Zhou, Jian Ma
Article Number: 72
Published online on: 19 January 2026

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Case Report

Identification of a novel KISS1R (GPR54) gene variant (c.505+2T>G) in a patient with congenital hypogonadotropic hypogonadism: A case report and literature review

Burak Menekse, Enes Ucgul, Abdullatif Bakir, Sema Hepsen, Ilknur Ozturk Unsal, Muhammed Kizilgul, Takako Araki, Erman Cakal
Article Number: 71
Published online on: 16 January 2026

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Case Report Open Access

Postoperative hypofractionated intensity-modulated proton therapy to control recurrent paraganglioma at the jugular foramen: A case report and literature review

Wei Wang, Yingxia Yuan, Jiwei Bai, Yue Zou, Dongxue Zhou, Jun Zhao, Shuyan Zhang, Zishen Wang, Jie Wang, Jingjing Kong, Lu Yang, Masashi Mizumoto, Hideyuki Sakurai, Shosei Shimizu
Article Number: 70
Published online on: 16 January 2026

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Article

Serum antithrombin III level predicts acute kidney injury in patients with traumatic brain injury

Ruoran Wang, Min He, Jianguo Xu
Article Number: 69
Published online on: 16 January 2026

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Retraction Open Access

[Retracted] β‑asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal‑regulated kinase signaling pathway

Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong Li
Article Number: 68
Published online on: 12 January 2026

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Case Report Open Access

Rare co‑occurrence of gastrointestinal stromal tumors and leiomyomas: A case report and review of the literature

Yu Zhang, Xiaoqiong Shi, Wenfu Xie, Meilin He, Shan Zhang, Xue Peng, Hao Lei, Xulei Li, Haiying Liu, Qiao Shu, Fangyuan Zou, Mingyong Wei
Article Number: 67
Published online on: 09 January 2026

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Article Open Access

No increased risk of hepatic enzyme abnormalities with non‑peptidic thrombopoietin receptor agonists in immune thrombocytopenia: A meta‑analysis of randomized controlled trials

Nan Shen, Rang Wu, Tiantian Lu, Song Liu, Yazhou Jiang, Jingjing Yan, Tao Ning, Chang Dong, Jianqin Li, Suyue Zhu
Article Number: 66
Published online on: 09 January 2026

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Case Report

Submucosal colonic fecalith mimicking a submucosal malignant tumor at the anastomotic site after colon cancer: A case report

Motoaki Yuhi, Masatsugu Hiraki, Shin Takesue, Mariko Hashiguchi, Megumi Nishiyama, Yoshiaki Egashira, Tatsuya Manabe, Hirokazu Noshiro
Article Number: 65
Published online on: 08 January 2026

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Article

Clinical characteristics of acute primary angle closure following COVID‑19 during the Omicron outbreak in China

Jianhui Zhang, Yingying Xue, Liu Zhang, Yuhong Wang, Shancheng Si
Article Number: 64
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Aberrant expression and mechanism of miR‑130b‑3p/phosphatase and tensin homolog in nephroblastoma in children

Yifeng Hu, Jingtie Yan
Article Number: 63
Published online on: 05 January 2026

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Case Report Open Access

Novel variants in STAG2 and PKD1 associate with multiple congenital malformations and autosomal dominant polycystic kidney disease in a Chinese family: A case report and literature review

Qi Yang, Qiang Zhang, Sheng Yi, Xunzhao Zhou, Yiyan Ruan, Shujie Zhang, Shang Yi, Qinle Zhang, Zailng Qin, Jingsi Luo
Article Number: 62
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 31 Issue 4

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Impact Factor: 2.3

Case Report

Sagittal sinus thrombosis in pregnancy: A case report

Zaheera Saadia, Misbah Ilyas, Jayd Saud Althwiny, Fai Alaqel, Alanoud Abdullah Alsufayri, Lujain Husain Almutairi
Article Number: 100
Published online on: 05 February 2026

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Article

Elevated PGE2 and COX‑2 expression in villous adenoma: Implications for electrolyte depletion syndrome

Shiki Fujino, Hiroyuki Fukuda, Katsuki Danno, Takashi Takeda, Masaya Higashiguchi, Kozo Noguchi, Takefumi Hirao, Aya Ito, Norikatsu Miyoshi, Yoshio Oka
Article Number: 99
Published online on: 04 February 2026

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Article Open Access

Wogonin as a potential therapeutic agent for psoriasis: Core target identification and validation

Yu Lu, Xiaomei Zhou, Yiyu Guo, Fengrui Zhang, Jirong Wang, Jinhong Ge, Yan Xiao, Dengke Yang
Article Number: 98
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Glibenclamide exacerbates adriamycin‑induced cardiotoxicity by activating oxidative stress‑induced endoplasmic reticulum stress in rats

Meng-Lin Liu, Meng-Long Wang, Jing-Jun Lv, Jie Wei, Jun Wan
Article Number: 97
Published online on: 04 February 2026

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Review

Key role of the autonomic nervous system in breast cancer (Review)

Min Wu, Zhiwu Zhang, Lu Zhou, Shiqi Liu, Qing Chen, Cui Guo, Shasha Zhao, Xuedan Chen
Article Number: 96
Published online on: 04 February 2026

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Review Open Access

Senescent hepatic stellate cells drive inflammation and disease progression in MASH (Review)

Zhiqi Han, Yiran She, Di Wu, Nuo Zhang, Zheyuan Liu, Zhongyuan Wang, Xiaoying Zhou, Shuo Li
Article Number: 95
Published online on: 04 February 2026

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Article Open Access

PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells

Zilong Zhang, Hangyu Zhou, Diliyaer Adili, Wei Zhu, Yong Liu, Wenzheng Zhou, Zhao Wang, Jie Li
Article Number: 94
Published online on: 04 February 2026

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Case Report

A novel human papillomavirus‑induced ‘doughnut wart’ lesion treated with 5‑aminolevulinic acid photodynamic therapy: A case report

Ke Li, Yitao Qian, Wenjing Zha, Lei Shi
Article Number: 93
Published online on: 04 February 2026

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Case Report Open Access

Comprehensive diagnosis and individualized treatment of multiple primary lung cancer: A case report

Guoxiong Zeng, Yunyan Zhou, Wang Wan, Biao Deng, Chunyuan Chen, Zhu Liang
Article Number: 92
Published online on: 03 February 2026

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Review Open Access

Pathophysiological mechanisms of fatigue and multidisciplinary management strategies (Review)

Hong Zhou, Wenwen Yu, Jiaming Lei, Runzhi Chang, Yingjia Cheng, Guorui Wang, Li Lin
Article Number: 91
Published online on: 03 February 2026

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Case Report Open Access

A rare upstream regulatory region mutation in APC presenting as classical familial adenomatous polyposis: A case report and literature review

Chi-Han Yang, Yen-Cheng Chen, Tsung-Kun Chang, Wei-Chih Su, Ching-Wen Huang, Hsiang-Lin Tsai, Jaw-Yuan Wang
Article Number: 90
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] lncRNA MIAT promote cell invasion and migration in esophageal cancer

Weiguo Zhang, Qiang Chen, Caipeng Lei
Article Number: 89
Published online on: 02 February 2026

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Review Open Access

Mitochondria‑driven ferroptosis in intervertebral disc degeneration: A novel target in age‑related spinal diseases (Review)

Yang Hou, Xiaolei Yang, Duorun Qiu, Lei Liu, Jiangang Shi, Yongfei Guo
Article Number: 88
Published online on: 02 February 2026

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Case Report

Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report

Jingxian Li, Fang Wang, Yuanshu Du, Yonghui Wang
Article Number: 87
Published online on: 02 February 2026

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Case Report Open Access

Gastric wall thickening and gastric outlet obstruction due to peritoneal metastasis in breast cancer: A case report

Bin He, Lin Ling Li, Ting Yu, Yu Tan, Ling Zhang
Article Number: 86
Published online on: 29 January 2026

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Article Open Access

Myrrh ameliorates endometriosis by enhancing ER stress‑related apoptotic cell death

Bo-Sung Kim, Minkyoung Cho, Jung Ho Han, Jung-Sook Jin, Sung-Jin Bae, Yunju Jo, Dongryeol Ryu, Yerim Joo, Seon Beom Kim, Jongkil Joo, Inhye Kim, Ki-Tae Ha
Article Number: 85
Published online on: 29 January 2026

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