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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2022 Volume 23 Issue 2

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Impact Factor: 2.2

Article Open Access

CBL knockdown protects cardiomyocytes against hypoxia‑reoxygenation injury by downregulating GRB2 expression

Zhengbing Lv, Xiaojia Luo, Biying Hong, Qiran Ye, Jianxiong Liu, Yongmei Hu
Article Number: 188
Published online on: 03 January 2022

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Review

Systematic review of the role of indocyanine green near‑infrared fluorescence in safe laparoscopic cholecystectomy (Review)

Dragos Serban, Dumitru Cristinel Badiu, Dragos Davitoiu, Ciprian Tanasescu, Mihail Silviu Tudosie, Alexandru Dan Sabau, Ana Maria Dascalu, Corneliu Tudor, Simona Andreea Balasescu, Bogdan Socea, Daniel Ovidiu Costea, Anca Zgura, Andreea Cristina Costea, Laura Carina Tribus, Catalin Gabriel Smarandache
Article Number: 187
Published online on: 30 December 2021

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Case Report

Bacterial endocarditis masked by COVID‑19: A case report

Mircea Bajdechi, Nicoleta Dorina Vlad, Mirela Dumitrascu, Elena Mocanu, Irina Magdalena Dumitru, Roxana Carmen Cernat, Sorin Rugină
Article Number: 186
Published online on: 30 December 2021

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Review Open Access

Restless legs syndrome: An overview of pathophysiology, comorbidities and therapeutic approaches (Review)

Andrei Vlasie, Simona Corina Trifu, Cristiana Lupuleac, Bianca Kohn, Mihai Bogdan Cristea
Article Number: 185
Published online on: 30 December 2021

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Case Report

Portal vein reconstruction with interposition of cryopreserved aortic graft: A case report and literature review

Nicolae Bacalbasa, Irina Balescu, Camelia Diaconu, Bogdan Socea, Florentina Gherghiceanu, Ovidiu Stiru, Vladislav Brasoveanu
Article Number: 184
Published online on: 30 December 2021

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Article Open Access

p‑Coumaric acid suppresses reactive oxygen species‑induced senescence in nucleus pulposus cells

Kunkun Sheng, Yan Li, Zhan Wang, Kai Hang, Zhaoming Ye
Article Number: 183
Published online on: 30 December 2021

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Article Open Access

Hydroxysafflor yellow A attenuates oxidative stress injury‑induced apoptosis in the nucleus pulposus cell line and regulates extracellular matrix balance via CA XII

Shuo Yang, Wenbo Liao
Article Number: 182
Published online on: 30 December 2021

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Article Open Access

Benzoyl‑xanthone derivative induces apoptosis in MCF‑7 cells by binding TRAF6

Xuan Zhao, Limei Ren, Xiaoru Wang, Guangxin Han, Shuo Wang, Qingguo Yao, Yonghao Qi
Article Number: 181
Published online on: 30 December 2021

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Article Open Access

Electrochemical monitoring of bronchial inflammation in pediatric athletes: A prospective study

Radu Diaconu, Florentina Dumitrescu, Loredana Stoica, Carmen Diaconu, Mihaela-Amelia Dobrescu, Adina-Dorina Glodeanu, Mihaela Ionescu, Nikolaos Mavritsakis, Doru Stoica
Article Number: 180
Published online on: 28 December 2021

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Review Open Access

Metabolic comorbidities of psoriasis (Review)

Daciana Elena Branisteanu, Ruxandra Angela Pirvulescu, Alina Elena Spinu, Elena Andrese Porumb, Mihaela Cojocaru, Alin Codrut Nicolescu, Daniel Constantin Branisteanu, Catalina Ioana Branisteanu, Andreea Dimitriu, Anisia Iuliana Alexa, Mihaela Paula Toader
Article Number: 179
Published online on: 28 December 2021

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Review Open Access

New strategies of diagnostic and therapeutic approach to emergencies in the evolution of patients with diabetes mellitus (Review)

Maria Forțofoiu, Ionela Mihaela Vladu, Mircea-Cătălin Forțofoiu, Rodica Pădureanu, Diana Clenciu, Dumitru Rădulescu, Vlad Pădureanu
Article Number: 178
Published online on: 28 December 2021

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Case Report Open Access

Malignant mixed Müllerian tumor of the fallopian tube: Case report and literature review

Alexandra Lavinia Cozlea, Mihai Gheorghe, Szilard Leo Kiss, Anas Fandi, Mihai Stanca, Simona Mocan, Mihai Emil Căpîlna, Nicolae Bacalbașa, Andreea Anamaria Moldovan
Article Number: 177
Published online on: 28 December 2021

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Review

Lung neuroendocrine tumors: A systematic literature review (Review)

Cornel Savu, Alexandru Melinte, Camelia Diaconu, Ovidiu Stiru, Florentina  Gherghiceanu, Ștefan Dragoș Octavian Tudorica, Oana Clementina Dumitrașcu, Angelica Bratu, Irina Balescu, Nicolae Bacalbasa
Article Number: 176
Published online on: 28 December 2021

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Case Report Open Access

Therapeutic challenges of psoriasis in the HIV‑infected patient: A case report

Manuela Arbune, Anca-Adriana Arbune, Elena Niculet, Lucretia Anghel, Silvia Fotea, Alin Laurentiu Tatu
Article Number: 175
Published online on: 28 December 2021

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Review Open Access

Continuous glucose monitoring devices: A brief presentation (Review)

Doina Andrada Mihai, Diana Simona Stefan, Daniela Stegaru, Georgiana Elena Bernea, Ileana Adela Vacaroiu, Toma Papacocea, Mircea Ovidiu Denis Lupușoru, Adriana Elena Nica, Ovidiu Stiru, Dorin Dragos, Octavian Gabriel Olaru
Article Number: 174
Published online on: 28 December 2021

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Case Report Open Access

Clinicopathological correlation of transient acantholytic dermatosis: A case report

Ilarie Brihan, Gyula László Fekete, Constanta Turda, Ovidiu Tica, Alina Cristiana Venter, Simona Ianosi, Carmen-Daniela Neagoe, Daciana Elena Branisteanu
Article Number: 173
Published online on: 28 December 2021

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Article Open Access

Effect of Src tyrosine kinase on a rat model of asthma

Min Wu, Jingping Yang, Tao Liu, Pengfei Xuan, Baoying Bu, Xiyuan Xu, Rina Wu
Article Number: 172
Published online on: 27 December 2021

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Article

Lectin‑type oxidized LDL receptor 1 modulates matrix metalloproteinase 2 production in peri‑implantitis

Qian Zhang, Tao Xu, Na Bai, Fei Tan, Hongmei Zhao, Jie Liu
Article Number: 171
Published online on: 27 December 2021

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Review Open Access

Fate of hematopoietic stem cells determined by Notch1 signaling (Review)

Yidong Ge, Jie Wang, Hui Zhang, Jinyun Li, Meng Ye, Xiaofeng Jin
Article Number: 170
Published online on: 27 December 2021

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Article Open Access

PRUNE2 inhibits progression of colorectal cancer in vitro and in vivo

Ting Li, Silin Huang, Wei Yan, Yu Zhang, Qiang Guo
Article Number: 169
Published online on: 27 December 2021

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Article Open Access

Gastrodin inhibits high glucose‑induced inflammation, oxidative stress and apoptosis in podocytes by activating the AMPK/Nrf2 signaling pathway

Luyan Huang, Minghai Shao, Yan Zhu
Article Number: 168
Published online on: 23 December 2021

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Article Open Access

Morphological and morphometric changes in the Purkinje cells of patients with essential tremor

Ioannis Mavroudis, Dimitrios Kazis, Foivos Petridis, Simela Chatzikonstantinou, Eleni Karantali, Samuel N. Njau, Vasiliki Costa, Alin Ciobica, Constantin Trus, Ioana Miruna Balmus, Stavros J. Baloyannis
Article Number: 167
Published online on: 23 December 2021

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Article Open Access

Complement regulation in ovine lymph nodes during early pregnancy

Leying Zhang, Lidong Cao, Pengfei Feng, Xu Han, Ling Yang
Article Number: 166
Published online on: 23 December 2021

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Article Open Access

MicroRNA‑195‑5p inhibits the progression of hemangioma via targeting SKI Retraction in /10.3892/etm.2024.12767

Bin Sun, Zhi Huang, Hua Yang, Xuya Zhao
Article Number: 165
Published online on: 22 December 2021

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Article Open Access

Roles of ERRα and TGF‑β signaling in stemness enhancement induced by 1 µM bisphenol A exposure via human neural stem cells

Panpan Dong, Ganghui Ye, Xinzhuo Tu, Ying Luo, Weitong Cui, Yuxin Ma, Lei Wei, Xuewen Tian, Qinglu Wang
Article Number: 164
Published online on: 22 December 2021

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Article Open Access

Changes of farnesoid X receptor and Takeda G‑protein coupled receptor 5 following biliary tract external drainage in hemorrhagic shock

Lu Wang, Huai-Wu He, Xiang Zhou, Yun Long
Article Number: 163
Published online on: 21 December 2021

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Article Open Access

Potential biomarkers of acute myocardial infarction based on co‑expression network analysis

Zhaohui Hu, Ruhui Liu, Hairong Hu, Xiangjun Ding, Yuyao Ji, Guiyuan Li, Yiping Wang, Shengquan Xie, Xiaohong Liu, Zhiwen Ding
Article Number: 162
Published online on: 21 December 2021

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Article Open Access

P2X7R antagonist protects against renal injury in mice with adriamycin nephropathy

Yanji Zhu, Min Liu, Wenlong Xun, Keliang Li, Xiangji Niu
Article Number: 161
Published online on: 21 December 2021

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Article Open Access

Unraveling the molecular mechanisms of hyperlipidemia using integrated lncRNA and mRNA microarray data

Bianling Xu, Nan Wang, Xuegong Xu, Yongmin Cai
Article Number: 160
Published online on: 20 December 2021

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Article

Diagnostic approach and treatment specificity in patients with focal lesions of the biliopancreatic area complicated by mechanical jaundice

Petro Muraviov, Boris Zaporozhchenko, Igor Borodaev, V.V. Kolodiy, Anatoliy Gorbunov, E.P. Kirpichnikova, Nicolae Bacalbasa, Irina Balescu, Makrem Harhouri
Article Number: 159
Published online on: 17 December 2021

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Article Open Access

Intestinal ischemia‑reperfusion induces the release of IL‑17A to regulate cell inflammation, apoptosis and barrier damage

Li Xiao, Wan-Hua Zhang, Yin Huang, Peng Huang
Article Number: 158
Published online on: 17 December 2021

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Article Open Access

APPL1 ameliorates myocardial ischemia‑reperfusion injury by regulating the AMPK signaling pathway

Yunguang Cen, Wei Liao, Taihao Wang, Daimin Zhang
Article Number: 157
Published online on: 17 December 2021

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Article Open Access

Analysis of long‑term anatomic results of radical mastoidectomy

Horia Mocanu, Adela-Ioana Mocanu, Gabriella Coadă, Alexandru Bonciu, Mihai-Adrian Schipor, Marian Rădulescu
Article Number: 156
Published online on: 17 December 2021

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Review

Signal transduction mechanism of exosomes in diabetic complications (Review)

Xueting Li, Shuo Shi, Dehuai Jing, Xinjian Li, Bin Zhang, Qingli Bie
Article Number: 155
Published online on: 17 December 2021

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Article Open Access

KDM2B overexpression prevents myocardial ischemia‑reperfusion injury in rats through regulating inflammatory response via the TLR4/NF‑κB p65 axis

Zijie Wei, Lihua Luo, Shuo Hu, Rongcheng Tian, Ziyou Liu
Article Number: 154
Published online on: 17 December 2021

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Review Open Access

Artificial intelligence applications and robotic systems in Parkinson's disease (Review)

Lacramioara Perju‑Dumbrava, Maria Barsan, Daniel Corneliu Leucuta, Luminita C. Popa, Cristina Pop, Nicoleta Tohanean, Stefan L. Popa
Article Number: 153
Published online on: 17 December 2021

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Review Open Access

Cardiovascular comorbidities in psoriasis (Review)

Daciana Elena Branisteanu, Alin Codrut Nicolescu, Daniel Constantin Branisteanu, Catalina Ioana Branisteanu, Andreea Corina Dragoi, Camelia Margareta Bogdanici, Mihaela Paula Toader, Andreea Lorena Tucaliuc, Andreea Dimitriu, Doru Daogaru, Ruxandra Angela Pirvulescu, Elena Andrese Porumb
Article Number: 152
Published online on: 17 December 2021

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Review Open Access

Adult female acne: Clinical and therapeutic particularities (Review)

Daciana Elena Branisteanu, Mihaela Paula Toader, Elena Andrese Porumb, Ionela Lacramioara Serban, Alin Constantin Pinzariu, Catalina Ioana Branisteanu, Anastasia Vicovan, Andreea Dimitriu, Isabela-Alexandra Fartusnic, Daniel Boda, Daniel Constantin Branisteanu, Ilarie Brihan, Alin Codrut Nicolescu
Article Number: 151
Published online on: 16 December 2021

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Article

Success rate of methotrexate in the conservative treatment of tubal ectopic pregnancies

Corina Grigoriu, Roxana Elena Bohiltea, Bianca Margareta Mihai, Corina Aurelia Zugravu, Florentina Furtunescu, Tiberiu Augustin Georgescu, Diana Ionela Munteanu
Article Number: 150
Published online on: 16 December 2021

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Article

Mucosal gene expression profile of stricturing Crohn's disease: A preliminary study

Cristian George Tieranu, Andrei Ovidiu Olteanu, Carmen Monica Preda, Nicolae Bacalbasa, Elena Milanesi, Maria Dobre, Ioana Tieranu, Teodora Ecaterina Manuc, Artsiom Klimko, Gabriel Becheanu, Elena Mirela Ionescu
Article Number: 149
Published online on: 16 December 2021

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Article Open Access

Silencing CoREST inhibits the viability and migration of fibroblast‑like synoviocytes in TNF‑α‑induced rheumatoid arthritis

Ziliang Yu, Feihu Chen, Hao Liu, Jianbo Fan, Xiaomin Ding, Xinhui Zhu, Shengyu Cui, Hong Yi, Xiaogang Zhou, Yalong Hu, Wei Liu
Article Number: 148
Published online on: 15 December 2021

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Article Open Access

Role of cyclin‑dependent kinase 5 in early brain injury following experimental subarachnoid hemorrhage

Yu Ding, Liexiang Zhang, Wei Zhou, Hai Lu, Xingde Gao, Jian Li, Jingde Liu, Xiaowang Niu, Jing Zheng
Article Number: 147
Published online on: 15 December 2021

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Article Open Access

Costal cartilage overgrowth does not induce pectus‑like deformation in the chest wall of a rat model

Vlad Laurentiu David, Maria Corina Stanciulescu, Florin George Horhat, Abhinav Sharma, Nilima Rajpal Kundnani, Bogdan Ciornei, Ramona Florina Stroescu, Marius Calin Popoiu, Eugen Sorin Boia
Article Number: 146
Published online on: 15 December 2021

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Review Open Access

Congenitally missing second permanent molars in non‑syndromic patients (Review)

Alexandru-Titus Farcașiu, Rodica Luca, Andreea Didilescu, Ioana-Andreea Stanciu, Catalina Farcasiu, Arina Vinereanu, Aneta Munteanu
Article Number: 145
Published online on: 15 December 2021

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Article Open Access

Therapeutic effect and mechanism of 4‑phenyl butyric acid on renal ischemia‑reperfusion injury in mice

Xinlei Wang, Yang Zhang, Kun Wuyun, Haixia Gong
Article Number: 144
Published online on: 15 December 2021

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Article Open Access

Galectin‑1 alleviates myocardial ischemia‑reperfusion injury by reducing the inflammation and apoptosis of cardiomyocytes

Dengke Ou, Dan Ni, Rong Li, Xiaobo Jiang, Xiaoxiao Chen, Hongfei Li
Article Number: 143
Published online on: 15 December 2021

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Article Open Access

MicroRNA‑126 and VEGF enhance the function of endothelial progenitor cells in acute myocardial infarction

Ying Zhang, Yi Xu, Ke Zhou, Guoying Kao, Jun Xiao
Article Number: 142
Published online on: 14 December 2021

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Article

Synergistic effect of Bruton's tyrosine kinase and TNF‑α in the regulation of rheumatoid arthritis and underlying mechanisms

Jinwan Du
Article Number: 141
Published online on: 14 December 2021

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Article

miR‑340‑5p inhibits pancreatic acinar cell inflammation and apoptosis via targeted inhibition of HMGB1

Yazhou Gao, Liming Wang, Zequn Niu, Hui Feng, Jie Liu, Jiangli Sun, Yanxia Gao, Longfei Pan
Article Number: 140
Published online on: 14 December 2021

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Article Open Access

Transplantation of IL‑1β siRNA‑modified bone marrow mesenchymal stem cells ameliorates type II collagen‑induced rheumatoid arthritis in rats

Shifeng Pan, Xuan Dong, Yan Wang, Tiansheng Zhou, Yuting Liu, An Zhou, Hua Xing
Article Number: 139
Published online on: 14 December 2021

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Article Open Access

Synchronous biliary gallstones and colorectal cancer: A single center analysis

Narcis Octavian Zarnescu, Eugenia Claudia Zarnescu, Ioana Dumitrascu, Alexandru Chirca, Nicoleta Sanda, Andreea Iliesiu, Radu Costea
Article Number: 138
Published online on: 13 December 2021

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Review Open Access

Diagnostic methods for the etiological assessment of infectious corneal pathology (Review)

Mihail Zemba, Otilia-Maria Dumitrescu, Andreea-Elena Dimirache, Daniel Constantin Branisteanu, Florian Balta, Marian Burcea, Andreea Dana Moraru, Sinziana Gradinaru
Article Number: 137
Published online on: 13 December 2021

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Review Open Access

Nasopharyngeal carcinoma: A new synthesis of literature data (Review)

Daniela Jicman (Stan), Elena Niculet, Mihaela Lungu, Cristian Onisor, Laura Rebegea, Doinita Vesa, Laura Bezman, Florin Ciprian Bujoreanu, Mihaela Ionela Sarbu, Raul Mihailov, Silvia Fotea, Alin Laurentiu Tatu
Article Number: 136
Published online on: 13 December 2021

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Case Report Open Access

Orthopaedic manifestations of neurofibromatosis type 1: A case report

Florentina Năstase, Diana Sabina Radaschin, Elena Niculeț, Andrei Vlad Brădeanu, Mădălina Codruța Verenca, Aurel Nechita, Valentin Chioncel, Lawrence Chukwudi Nwabudike, Liliana Baroiu, Eduard Drima Polea, Silvia Fotea, Lucretia Anghel, Alexandru Nechifor, Alin Laurenţiu Tatu
Article Number: 135
Published online on: 13 December 2021

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Review Open Access

Old and new therapeutic strategies in systemic sclerosis (Review)

Carmen Bobeica, Elena Niculet, Alin Laurentiu Tatu, Mihaela Craescu, Dan Vata, Laura Statescu, Alina Viorica Iancu, Carmina Liana Musat, Miruna Luminita Draganescu, Cristian Onisor, Mihaela Lungu, Silvia Fotea, Aurel Nechita, Bogdan Ioan Stefanescu, Laura Gheuca‑Solovastru
Article Number: 134
Published online on: 13 December 2021

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Correction Open Access

[Corrigendum] Baicalin promotes the viability of Schwann cells in vitro by regulating neurotrophic factors

Wenpu Zuo, Huayu Wu, Kun Zhang, Peizhen Lv, Fuben Xu, Weizhe Jiang, Li Zheng, Jinmin Zhao
Article Number: 133
Published online on: 13 December 2021

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Article Open Access

Pitavastatin maintains MAPK7 expression and alleviates angiotensin II‑induced vascular endothelial cell inflammation and injury

Min Li, Xiaohua Liu
Article Number: 132
Published online on: 13 December 2021

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Article Open Access

Knockdown of long non‑coding RNA NEAT1 relieves inflammation of ulcerative colitis by regulating the miR‑603/FGF9 pathway

Fengdong Li, Hui Liu, Jinjin Fu, Li Fan, Shuangshuang Lu, Huahui Zhang, Zhanju Liu
Article Number: 131
Published online on: 10 December 2021

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VEGF mitigates bisphosphonate‑induced apoptosis and differentiation inhibition of MC3T3‑E1 cells

Yao Duan, Hejia Li, Xiaohong Dong, Zhaoli Geng, Xinyi Xu, Yi Liu
Article Number: 130
Published online on: 10 December 2021

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Risk factors for fluctuations in corneal endothelial cell density (Review)

Renata Vaiciuliene, Neda Rylskyte, Gabija Baguzyte, Vytautas Jasinskas
Article Number: 129
Published online on: 10 December 2021

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CPNE3 interaction with RACK1 protects against myocardial ischemia/reperfusion injury

Xiaoqun Zhang, Xue Han, Yanan Zhang
Article Number: 128
Published online on: 10 December 2021

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miR‑27b attenuates dexamethasone‑inhibited proliferation and osteoblastic differentiation in MC3T3‑E1 cells by targeting PPARγ2

Huicheng Lv, Tieyi Yang, Aimin He, Mingbo Wang, Haisheng Jia, Min Ma, Siqin Li
Article Number: 127
Published online on: 10 December 2021

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Hydrogen‑rich saline alleviates early brain injury through inhibition of necroptosis and neuroinflammation via the ROS/HO‑1 signaling pathway after traumatic brain injury

Yun Hu, Xiaoyan Feng, Junhui Chen, Yan Wu, Liuyan Shen
Article Number: 126
Published online on: 09 December 2021

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Serous otitis media: Clinical and therapeutic considerations, including dexamethasone (C22H29FO5) intratympanic injection

Cristian Mârțu, Sebastian Cozma, Bogdan Cobzeanu, Doina Vesa, Corina Butnaru, Dragoș Bularda, Adeline Cumpătă, Luminița Rădulescu
Article Number: 125
Published online on: 07 December 2021

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Nursing procedures for advanced dementia: Traditional techniques versus autonomous robotic applications (Review)

Liliana David, Stefan L. Popa, Maria Barsan, Lucian Muresan, Abdulrahman Ismaiel, Luminita C. Popa, Lacramioara Perju‑Dumbrava, Mihaela Fadgyas Stanculete, Dan L. Dumitrascu
Article Number: 124
Published online on: 07 December 2021

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Research on demographic, clinical and paraclinical aspects in pregnant women infected with Toxoplasma gondii

Andrei Csep, Luminița Ligia Vaida, Bianca-Maria Negruțiu, Bianca Ioana Todor, Claudia Teodora Judea‑Pusta, Camelia Buhaș, Cristian Sava
Article Number: 123
Published online on: 07 December 2021

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Benefits of crenotherapy in digestive tract pathology (Review)

Magdalena Dumitrescu, Madalina Gabriela Iliescu, Laura Mazilu, Sergiu Ioan Micu, Adrian Paul Suceveanu, Felix Voinea, Claudia Voinea, Anca Pantea Stoian, Andra-Iulia Suceveanu
Article Number: 122
Published online on: 07 December 2021

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Treatment of patients with Covid‑19 with a high dose of ulinastatin

Hai Huang, Ping-Fang Hu, Liang-Liang Sun, Yi-Bin Guo, Qiong Wang, Zhi-Min Liu, Ji-Zhong Yin, Pei-Mei Shi, Zong-Li Yuan, Wei-Fen Xie
Article Number: 121
Published online on: 07 December 2021

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Bazedoxifene activates the angiotensin II‑induced HUVEC hypertension model by targeting SIRT1

Qian Yu, Jin Zhao, Baotang Liu
Article Number: 120
Published online on: 07 December 2021

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Role of heparinase in the gastrointestinal dysfunction of sepsis (Review)

Ting-Ting Chen, Jia-Jun Lv, Ling Chen, Yu-Wei Gao, Li-Ping Liu
Article Number: 119
Published online on: 06 December 2021

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RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1 Corrigendum in /10.3892/etm.2022.11255

Yajuan Huang, Yufeng Zou, Zhigang Jie
Article Number: 118
Published online on: 06 December 2021

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Cytomorphological study of thyroid carcinoma

Iuliana Mohorea, Dana Terzea, Daniela Mihalache, Bogdan Socea, Dragoş Şerban, Mihai Ceausu
Article Number: 117
Published online on: 06 December 2021

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Salvianolic acid B inhibits the progression of liver fibrosis in rats via modulation of the Hedgehog signaling pathway

Shanjun Tao, Renjie Duan, Tong Xu, Jiao Hong, Wenjie Gu, Aiqin Lin, Likai Lian, Haoyu Huang, Jiangtao Lu, Tiechen Li
Article Number: 116
Published online on: 06 December 2021

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Predictive value of using plasma long non‑coding RNAs ANRIL and HOXA11‑AS for in‑stent restenosis

Zhijiang Jin, Hongfeng Shen, Wei Cha, Haijiang Xia, Longbin Liu
Article Number: 115
Published online on: 06 December 2021

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Review

Tyrosine kinase inhibitors in breast cancer (Review)

George Iancu, Dragos Serban, Cristinel Dumitru Badiu, Ciprian Tanasescu, Mihai Silviu Tudosie, Corneliu Tudor, Daniel Ovidiu Costea, Anca Zgura, Raluca Iancu, Danut Vasile
Article Number: 114
Published online on: 03 December 2021

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Overview of the anatomical basis of the piriformis syndrome‑dissection with magnetic resonance correlation

Ofelia-Costina Goidescu, Mihaly Enyedi, Adrian-Daniel Tulin, Raluca Tulin, Ileana Adela Vacaroiu, Adriana Elena Nica, Dorin Dragos, Dorin Ionescu, Dragos Georgescu, Adrian Miron, Florin-Mihail Filipoiu
Article Number: 113
Published online on: 03 December 2021

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Morphometric study regarding ophthalmic and internal carotid arteries utilizing computed tomography angiography

Radu Andrei Baz, Sanda Jurja, Radu Ciuluvica, Cristian Scheau, Radu Baz
Article Number: 112
Published online on: 03 December 2021

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Heavy metal ion concentration in the amniotic fluid of preterm and term pregnancies from two cities with different industrial output

Radu Ionut Neamtu, Marius Craina, George Dahma, Alin Viorel Popescu, Adelina Geanina Erimescu, Ioana Citu, Amadeus Dobrescu, Florin George Horhat, Dan Dumitru Vulcanescu, Florin Gorun, Elena Silvia Bernad, Andrei Motoc, Ioan Cosmin Citu
Article Number: 111
Published online on: 03 December 2021

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October-2026 Volume 32 Issue 4

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Promoting expertise knowledge sharing in paediatric virology: An update (Review)

Ioannis N. Mammas, Anna Kramvis, Anastasia Stouraiti, Tina Dalianis, Patra Koletsi, Georgia Papaioannou, Alexia Papatheodoropoulou, Chryssie Koutsaftiki, Paraskevi Korovessi, Simon B. Drysdale, Maria Theodoridou, Demetrios A. Spandidos
Article Number: 293
Published online on: 07 September 2026

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ACT001 suppresses ox‑LDL‑mediated macrophage ferroptosis via activating the NRF2 pathway: An in vitro mechanistic study relevant to atherosclerosis

Yangyang Tao, Yuwu Chen, Yonghou Zhao, Jianbo Cai
Article Number: 292
Published online on: 07 September 2026

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From mitochondria to innate immunity: The mtDNA‑driven cGAS/STING‑NLRP3 cascade and its therapeutic implications in neurodegenerative diseases (Review)

Hui Liu, Yao Zhang, Ziliang Zhuo, Wei Zhong, Manyun Yan, Zhongbo Zhao
Article Number: 291
Published online on: 04 September 2026

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Active abdominal compression‑decompression cardiopulmonary resuscitation attenuates neuroinflammation associated with TLR4/NF‑κB signaling in a rat model of cardiac arrest

Xiaopeng  Liu, Xiaoqing  Yang, Yifan  Huang, Xinyuan  Kong, Jiankai  Gao, Hongyu  Wang, Sisen  Zhang
Article Number: 290
Published online on: 04 September 2026

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ASF1A: A versatile histone chaperone bridging chromatin dynamics, disease mechanisms and clinical potential (Review)

Jun Yin, Xiaojian Zhuo, Lihui Wen, Xianmin Wang, Tongyong Luo, Qingsong Wang
Article Number: 289
Published online on: 02 September 2026

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Preventive administration of verapamil attenuates dextran sulfate sodium‑induced colitis in mice

Natsuki Ota, Keisuke Sato, Ryosuke Tatsunami
Article Number: 288
Published online on: 02 September 2026

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Gut microbiome dynamics in acute infectious diarrhea: A conceptual framework from acute dysbiosis toward precision restoration (Review)

Cong Yuan, Jiale Tong, Weiwei Qian, Qian He
Article Number: 287
Published online on: 02 September 2026

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Mapping and anatomo‑surgical techniques for language preservation in brain tumours (Review)

Xiaoyuan Liu, Jia Ouyang, Jiangfei Wang
Article Number: 286
Published online on: 02 September 2026

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[Corrigendum] Circular RNA expression profiles significantly altered in UVA‑irradiated human dermal fibroblasts

Mengbi Lin, Yue Zheng, Qian Li, Yufang Liu, Qingfang Xu, Yuying Li, Wei Lai
Article Number: 285
Published online on: 01 September 2026

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Generation and evaluation of multimers of anti C‑reactive protein Nb and alkaline phosphatase based on three self‑assembly peptides

Honghe Li, Chenchen Zhou, Xiaomei Zhang, Ning Ding, Qiong Wu, Junming Li, Yang Zheng, Xuejun Hu
Article Number: 284
Published online on: 28 August 2026

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New insights into diagnostic values and mechanisms of ferroptosis associated with immune infiltration in diabetic kidney disease

Ying Tan, Zihui Liu, Siyuan Song, Lingling Zhu, Yun She, Xiqiao Zhou, Jiangyi Yu, Qianhua Yan
Article Number: 283
Published online on: 28 August 2026

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Biological mechanisms underlying the effects of low‑magnitude mechanical stress in osteoporosis (Review)

Zhi Liu, Dan Han, Yanfei Wang, Hongfan Li, Xuedong Pei, Zhijing Song
Article Number: 282
Published online on: 28 August 2026

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Expression of Concern Open Access

[Expression of Concern] Transformation of nomifensine using ionizing radiation and exploration of its anticancer effects in MCF‑7 cells

Seong Hee Kang, Dong-Ho Bak, Byung Yeoup Chung, Hyoung-Woo Bai
Article Number: 281
Published online on: 21 August 2026

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Retrospective study of infusion‑related reactions in subcutaneous daratumumab administration in Japan

Yoko Ino, Kazuhide Tanaka, Fuka Ito, Nao Yamagishi, Futa Takemura, Masahiro Yasuda, Senji Kasahara
Article Number: 280
Published online on: 20 August 2026

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[Retracted] Combined effects of Lenvatinib and iodine‑131 on cell apoptosis in nasopharyngeal carcinoma through inducing endoplasmic reticulum stress

Guoyu Wang, Juhua Zhuang, Jing Ni, Ying Ye, Saifei He, Wei Xiai
Article Number: 279
Published online on: 17 August 2026

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PDK1/AKT signaling is involved in the anti‑tumor effect of gramine and cisplatin chemoresistance in ovarian cancer cells

Haiyan Wang, Ruiming Zheng, Bujun Wang, Sumiao Hong, Hongxia Chen
Article Number: 278
Published online on: 14 August 2026

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Integrating clinical outcomes with molecular simulations to guide the selection of non‑classical EGFR‑TKIs: A comprehensive analysis and development of treatment strategies

Fang Wei, Niu Niu, Chang Li, Ge Gao, Nan Li, Yan Wang
Article Number: 277
Published online on: 14 August 2026

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Case Report Open Access

Clinicopathological analysis of neuroendocrine carcinoma discovered incidentally in hemorrhoids: A case report and literature review

Bin Huang, Haiyan Zhou, Jianping Shi, Hongsheng Liu
Article Number: 276
Published online on: 12 August 2026

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Mechanism of microRNA‑30b‑5p enhancing the response of MDA‑MB‑231 cells to cisplatin by regulating RAP1B expression

Kewei Tang, Site Bai, Yajun Tong, Songjiang Liu, Leilan Yin, Ludi Ou, Qinghua Yin, Qiang Zhou
Article Number: 275
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Platelet‑rich plasma shows beneficial effects for patients with knee osteoarthritis by suppressing inflammatory factors

Guilin Huang, Sha Hua, Tuanmin Yang, Jianbing Ma, Wenxing Yu, Xiujin Chen
Article Number: 274
Published online on: 12 August 2026

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Establishment of a novel asymmetric force degenerative lumbar scoliosis aging bipedal rat model

Jing Peng, Daigui Cao, Xu Zhou, Zhiwei Liu, Xinxing Wang, Anwei Zhang, Kai Shen
Article Number: 273
Published online on: 11 August 2026

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Case Report Open Access

Rapid diagnosis of Chlamydia psittaci pneumonia with pleural effusion using multiplex PCR‑based targeted next‑generation sequencing: A case report

Yang Jin, Liqun He, Jiankun Wang, Tao Ren, Hansheng Wang, Yue Wang
Article Number: 272
Published online on: 11 August 2026

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Sanguinarine chloride inducing ferroptosis and downregulating GPX4 expression in liver cancer: An integrated in silico, in vitro and in vivo study

Wen Ouyang, Jianxin Gao, Jing Liu, Lulu Qin, Bang Liu, Ying He, Dai Zhou
Article Number: 271
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Activated protein C overexpression suppresses the pyroptosis of subarachnoid hemorrhage model cells by regulating the NLRP3 inflammasome pathway

Ai Yan, Xuyan Pan, Xianqiang Wen, Xiaohu Nie, Yuntao Li
Article Number: 270
Published online on: 10 August 2026

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RPLP0 drives diffuse large B‑cell lymphoma cell proliferation through reactive oxygen species‑dependent AKT/mTOR activation and inhibition of stress‑induced autophagy

Shanshan Wang, Xutao Yang, Rochelle Mcgowan, Belinda Hodge, Daniel Shan, Nicolas Miller, Jiahong Tang
Article Number: 269
Published online on: 07 August 2026

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Baseline neutrophil‑to‑lymphocyte ratio is not associated with chemotherapy‑induced nausea and vomiting in patients with breast cancer: A single‑center retrospective cohort study

Ruhper Cekin, Akif Dogan
Article Number: 268
Published online on: 07 August 2026

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Case Report Open Access

First case of neonatal bloodstream infection caused by Malassezia furfur in mainland China diagnosed via metagenomic next‑generation sequencing: A case report

Shanshan Gao, Lanlan Song, Qiujuan Feng, Yazhen Li, Huiqiang Liang, Ke Lei, Zheng Li, Peter Kisembo
Article Number: 267
Published online on: 06 August 2026

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Article

Comparative analysis of early and late recurrence rates in perianal fistula surgery

Ahmed Taha, Hi̇kmet Haşemi̇, Mutali̇p Ertuş, Bülent Özçeti̇n
Article Number: 266
Published online on: 06 August 2026

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Case Report

Cystic lymphangioma presenting as an ovarian mass in an adolescent: A case report and literature review

Rui Sun, Chun-Run Yang
Article Number: 265
Published online on: 05 August 2026

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Case Report

Postmenopausal osseous metaplasia of the endometrium: An uncommon histopathological entity: A case report

Emmanouela Aliki Almperi, Chrysoula Margioula Siarkou, Aristarchos Almperis, Nikoleta Dimitra Savvidou, Stamatios Petousis
Article Number: 264
Published online on: 05 August 2026

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Experimental evaluation of Curcuma Longa in docetaxel‑induced systemic toxicity: Functional hepatorenal and target organ analysis

Isabella Morais Tavares Huber, Emerson Luiz Botelho Lourenço, Salviano Tramontin Bellettini, Guilherme Donadel, João Francisco Velasquez Matumoto, Sandra Marisa Pelloso, Maria Dalva De Barros Carvalho, Stéfane Lele Rossoni, Mariana Morais Tavares Colferai, Diego Ricardo Colferai, Roberto Kenji Nakamura Cuman, Leonardo Garcia Velasquez
Article Number: 263
Published online on: 04 August 2026

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Case Report Open Access

Nasopharyngeal carcinoma with inguinal lymph node metastasis: A case report

Zhibin Lin, Shiliang Li, Donghong Yang, Tongyuan Deng, Haiwen Li, Yongcun Wang
Article Number: 262
Published online on: 04 August 2026

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Case Report

Adult‑onset focal nodular non‑exophytic nesidioblastosis mimicking insulinoma detected by endoscopic ultrasonography: A case report

Mesut Pekmez, Ümit Özçelik, Kemal Yandakçi, Alper Bilal Özkardeş
Article Number: 261
Published online on: 04 August 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑221 regulates cell activity and apoptosis in acute lymphoblastic leukemia via regulating PTEN

Lingyan Zhang, Zibin Bu, Juan Shen, Liping Shang, Yuanyuan Chen, Ping Zhang, Yan Wang
Article Number: 260
Published online on: 29 July 2026

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Predicting lower extremity deep vein thrombosis in elderly patients with hip fracture: A machine learning model with emphasis on diabetes as a key risk factor

Qian Song, Ping'an Shi, Peng Tian, Aijun Chao, Yinguang Zhang, Qiang Dong
Article Number: 259
Published online on: 29 July 2026

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Spatial specificity of Epstein‑Barr virus infection in gastric cancer: A 44‑case clinicopathological analysis

Xuming Wang, Longkuan Xu, Xiaozhen Yang, Xiaolu Yuan, Houliang Lu, Qiong Liu, Lijiang Liu
Article Number: 258
Published online on: 29 July 2026

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Crocin I delays cellular senescence potentially via modulating SIRT1/PKM2 expression to improve lactate homeostasis in vitro

Yicheng Fu, Zhiwei Ding, Yunchuang Chang, Chunxia Wu, Sanying Wang, Genxiang Mao, Huili Su
Article Number: 257
Published online on: 29 July 2026

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Case Report

Immune‑mediated liver injury caused by checkpoint inhibitors: A case series and review of the literature

Maria Kyrkasiadou, Anastasios Kyriazoglou, Ioannis Kotsantis, Panagiota Economopoulou, George Kavourakis, Roubini Zakopoulou, Maria Anastasiou, Anastasios Pantazopoulos, Anna Boulouta, Myrto Moutafi, Niki Gavrielatou, Periklis Foukas, Menelaos Samaras, Konstantinos Palialexis, Amanda Psyrri
Article Number: 256
Published online on: 29 July 2026

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Retraction Open Access

[Retracted] Reduced expression levels of the death‑associated protein kinase and E‑cadherin are correlated with the development of esophageal squamous cell carcinoma

Jianwen Zhai, Xiaogang Yang, Yanli Zhang, Qingbin Qi, Jigang Hu, Qiaomei Wang
Article Number: 255
Published online on: 27 July 2026

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Hematopoietic cell‑specific knockout Hspa9 impairs natural killer cell function and alters the Akt/mTOR axis in mice

Xiaokang Zeng, Jieyu Zhang, Caiying Liang, Jie Yao, Zuqiang Wu
Article Number: 254
Published online on: 24 July 2026

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Comparative study on mouse models of acute exacerbation of pulmonary fibrosis

Xu Ye, Mingrui Zhang, Mengying Liu, Huihui Zhu, Xiaoling Ye, Cheng Jiang, Qi Li, Xinmei Huang, Mengshu Cao
Article Number: 253
Published online on: 24 July 2026

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Correction Open Access

[Corrigendum] TBL1XR1 as a potential therapeutic target that promotes epithelial‑mesenchymal transition in lung squamous cell carcinoma

Yuehua Zhao, Hao Lin, Jingwei Jiang, Mengxi Ge, Xiaohua Liang
Article Number: 252
Published online on: 23 July 2026

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November-2026 Volume 32 Issue 5

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Impact Factor: 2.2

Review Open Access

Carrageenan‑induced immunothrombotic models in rodents (Review)

Xiaomu Ma, Daihan Wu, Simin Lv
Article Number: 305
Published online on: 16 September 2026

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Retraction Open Access

[Retracted] Role of peptidylarginine deiminase type 4 in gastric cancer 

Jiang Xin, Xiuqi Song
Article Number: 304
Published online on: 15 September 2026

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Immune checkpoint inhibitor‑induced myocarditis with myositis and/or myasthenia gravis overlap syndrome: A case series

Qing Sun, Qing Liu, Jiabin Zheng, Yanni Lou, Huijuan Cui, Junyu Ma, Yu Wang, Dantao Peng, Weihe Zhang, Renbin Wang
Article Number: 303
Published online on: 14 September 2026

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Cardiovascular health metrics and the risk of metabolic dysfunction‑associated steatosis liver disease: A meta‑analysis

Gang Fan, Hong Zuo, Bo Liu
Article Number: 302
Published online on: 14 September 2026

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Article Open Access

Multiple relapses of cryptogenic organizing pneumonia: A case report

Sheng Xu, Beibei Li, Yanmin Li, Jian Sun, Qiang Wang
Article Number: 301
Published online on: 11 September 2026

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A diagnostic and classification model integrating cTnI, CK‑MB, MYO and NT‑proBNP for cardiovascular diseases

Huaxin Zhang, Jianan Wang, Qi Li, Tong Zhi, Xiandong Chang
Article Number: 300
Published online on: 11 September 2026

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Case Report Open Access

A rare suprasellar lesion with multifocal central nervous system involvement in clinically diagnosed von Hippel‑Lindau disease: A case report

Zekai Wu, Lei Zhang, Meng Tan, Laian Zhang
Article Number: 299
Published online on: 11 September 2026

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Case Report Open Access

Reversible osimertinib‑associated heart failure mimicking cancer recurrence in EGFR‑mutated non‑small cell lung cancer after pneumonectomy: A case report

Hirona Yokoyama, Nobuhito Hara, Rika Sasaki, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Hitoshi Nakagawa, Takeshi Kawaguchi, Masatsugu Hamaji, Yuji Nitta, Maiko Takeda, Masayuki Takeda
Article Number: 298
Published online on: 11 September 2026

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Regenerative endodontic treatment for premolars with apical root segment separation and extensive periapical lesions secondary to severe inflammatory root resorption: A report of two cases

Qian Wu, Daniel J. Yen
Article Number: 297
Published online on: 11 September 2026

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Retraction Open Access

[Retracted] Hsp70 inducer, 17‑allylamino‑demethoxygeldanamycin, provides neuroprotection via anti‑inflammatory effects in a rat model of traumatic brain injury

Youquan Gu, Jun Chen, Tianhong Wang, Chaoning Zhou, Zhaodong Liu, Lanhua Ma
Article Number: 296
Published online on: 10 September 2026

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Case Report

Relapsed/refractory multiple myeloma with extramedullary plasmacytomas successfully rechallenged with humanized B‑cell maturation antigen‑directed chimeric antigen receptor T‑cell immunotherapy in an advanced disease stage: A case report

Runfeng Zhang, Lili Cheng, Jinghua Liu, Lu Zhang, Junling Zhuang
Article Number: 295
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] JWA regulates human esophageal squamous cell carcinoma and human esophageal cells through different mitogen‑activated protein kinase signaling pathways

Jie Lin, Tieliang Ma, Xiaodong Jiang, Zhijun Ge, Weiliang Ding, Yuanyuan Wu, Guojun Jiang, Jiake Feng, Guoxing Cui, Yongfei Tan
Article Number: 294
Published online on: 07 September 2026

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