Open Access

Adult female acne: Clinical and therapeutic particularities (Review)

  • Authors:
    • Daciana Elena Branisteanu
    • Mihaela Paula Toader
    • Elena Andrese Porumb
    • Ionela Lacramioara Serban
    • Alin Constantin Pinzariu
    • Catalina Ioana Branisteanu
    • Anastasia Vicovan
    • Andreea Dimitriu
    • Isabela-Alexandra Fartusnic
    • Daniel Boda
    • Daniel Constantin Branisteanu
    • Ilarie Brihan
    • Alin Codrut Nicolescu
  • View Affiliations

  • Published online on: December 16, 2021     https://doi.org/10.3892/etm.2021.11074
  • Article Number: 151
  • Copyright: © Branisteanu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Acne is a chronic inflammatory condition affecting the pilosebaceous unit that was traditionally viewed as a disease of the adolescence. However, over the past several years, an increasing number of adult women have been reported to suffer from this condition. The prevalence of adult female acne ranges between 12 and 54%. Two clinical types can be distinguished in this population, a ‘retentional’ and an ‘inflammatory’ type, which usually tend to overlap. In terms of evolution, three main subtypes can be identified: Persistent acne, which is the most frequent subtype, late‑onset acne and recurrent acne. This type of acne is mainly mild‑to‑moderate in severity and may be refractory to conventional treatment. The etiopathogenesis is complex and has yet to be fully elucidated. It appears to involve an interaction among genetic predisposition, hormonal factors, and chronic activation of the innate immune system overlapping with external factors, such as daily stress, Western‑type diet, use of tobacco and cosmetics. The treatment may be challenging and a holistic approach is required, with special attention to the individual needs and particularities of adult women. Both topical and systemic treatments are available, with hormonal therapies being of special value in this population. The aim of the present article was to provide up‑to‑date, evidence‑based information on the clinical presentation, etiopathogenesis and treatment of adult female acne.
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February-2022
Volume 23 Issue 2

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Copy and paste a formatted citation
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Spandidos Publications style
Branisteanu DE, Toader MP, Porumb EA, Serban IL, Pinzariu AC, Branisteanu CI, Vicovan A, Dimitriu A, Fartusnic I, Boda D, Boda D, et al: Adult female acne: Clinical and therapeutic particularities (Review). Exp Ther Med 23: 151, 2022.
APA
Branisteanu, D.E., Toader, M.P., Porumb, E.A., Serban, I.L., Pinzariu, A.C., Branisteanu, C.I. ... Nicolescu, A.C. (2022). Adult female acne: Clinical and therapeutic particularities (Review). Experimental and Therapeutic Medicine, 23, 151. https://doi.org/10.3892/etm.2021.11074
MLA
Branisteanu, D. E., Toader, M. P., Porumb, E. A., Serban, I. L., Pinzariu, A. C., Branisteanu, C. I., Vicovan, A., Dimitriu, A., Fartusnic, I., Boda, D., Branisteanu, D. C., Brihan, I., Nicolescu, A. C."Adult female acne: Clinical and therapeutic particularities (Review)". Experimental and Therapeutic Medicine 23.2 (2022): 151.
Chicago
Branisteanu, D. E., Toader, M. P., Porumb, E. A., Serban, I. L., Pinzariu, A. C., Branisteanu, C. I., Vicovan, A., Dimitriu, A., Fartusnic, I., Boda, D., Branisteanu, D. C., Brihan, I., Nicolescu, A. C."Adult female acne: Clinical and therapeutic particularities (Review)". Experimental and Therapeutic Medicine 23, no. 2 (2022): 151. https://doi.org/10.3892/etm.2021.11074