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Case Report Open Access

Visual impairment in immunoglobulin G4‑related disease: A case report

  • Authors:
    • Xue Wang
    • Xuren Sun
    • Ran Ao
    • Zilu Zeng
    • Dan Li
    • Yiling Li
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110000, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 200
    |
    Published online on: January 11, 2021
       https://doi.org/10.3892/etm.2021.9633
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Abstract

The present study reports on the case of a 50‑year‑old male with sinusitis, diplopia, secretory otitis media and skin eczema for >14 years. The patient presented with visual impairment in both eyes and subxiphoid pain on admission to the First Affiliated Hospital of China Medical University (Shenyang, China). Orbital CT revealed a slightly thickened left inferior rectus muscle. Due to a periocular mass, enlarged lymph nodes, elevated serum immunoglobulin G4 (IgG4) levels and enriched IgG4‑positive plasma cells in the lymph nodes, the diagnosis of IgG4‑related disease (IgG4‑RD), possibly involving at least 10 organs, was established. Following treatment with methylprednisolone, the serum IgG4 levels decreased to normal and binocular vision returned to normal. Unlike previously reported cases, the present case exhibited no swollen masses around the optic nerve. The purpose of the present case report was to improve the understanding of IgG4‑RD.
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Copy and paste a formatted citation
Spandidos Publications style
Wang X, Sun X, Ao R, Zeng Z, Li D and Li Y: Visual impairment in immunoglobulin G4‑related disease: A case report. Exp Ther Med 21: 200, 2021.
APA
Wang, X., Sun, X., Ao, R., Zeng, Z., Li, D., & Li, Y. (2021). Visual impairment in immunoglobulin G4‑related disease: A case report. Experimental and Therapeutic Medicine, 21, 200. https://doi.org/10.3892/etm.2021.9633
MLA
Wang, X., Sun, X., Ao, R., Zeng, Z., Li, D., Li, Y."Visual impairment in immunoglobulin G4‑related disease: A case report". Experimental and Therapeutic Medicine 21.3 (2021): 200.
Chicago
Wang, X., Sun, X., Ao, R., Zeng, Z., Li, D., Li, Y."Visual impairment in immunoglobulin G4‑related disease: A case report". Experimental and Therapeutic Medicine 21, no. 3 (2021): 200. https://doi.org/10.3892/etm.2021.9633
Copy and paste a formatted citation
x
Spandidos Publications style
Wang X, Sun X, Ao R, Zeng Z, Li D and Li Y: Visual impairment in immunoglobulin G4‑related disease: A case report. Exp Ther Med 21: 200, 2021.
APA
Wang, X., Sun, X., Ao, R., Zeng, Z., Li, D., & Li, Y. (2021). Visual impairment in immunoglobulin G4‑related disease: A case report. Experimental and Therapeutic Medicine, 21, 200. https://doi.org/10.3892/etm.2021.9633
MLA
Wang, X., Sun, X., Ao, R., Zeng, Z., Li, D., Li, Y."Visual impairment in immunoglobulin G4‑related disease: A case report". Experimental and Therapeutic Medicine 21.3 (2021): 200.
Chicago
Wang, X., Sun, X., Ao, R., Zeng, Z., Li, D., Li, Y."Visual impairment in immunoglobulin G4‑related disease: A case report". Experimental and Therapeutic Medicine 21, no. 3 (2021): 200. https://doi.org/10.3892/etm.2021.9633
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