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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March-2021 Volume 21 Issue 3

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Impact Factor: 2.3

Article Open Access

Femtosecond‑LASIK outcomes using the VisuMax®‑MEL® 80 platform for hyperopia and hyperopic astigmatism refractive surgery

Bogdana Tăbăcaru, Horia Tudor Stanca, Ruxandra Angela Pîrvulescu, Simona Stanca, Ciprian Danielescu, Mihnea Munteanu, Cosmin Roșca, Adrian Cosmin Teodoru
Article Number: 288
Published online on: 26 January 2021

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Review

Thrombotic risk in antiphospholipidic syndrome: From hypothesis to current evidence (Review)

Claudia Mihaela Gavriș, Laurențiu Dănuț Nedelcu, Alina Mihaela Pascu
Article Number: 287
Published online on: 26 January 2021

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Article Open Access

Correlations of sialic acid with glycated hemoglobin A1c and glycemia in postmenopausal women with type‑2 diabetes mellitus

Octavian Gabriel Olaru, Gianina Ioana Constantin, Catalina Monica Pena
Article Number: 286
Published online on: 26 January 2021

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Article Open Access

Accelerated vs. conventional collagen cross‑linking for infectious keratitis

Ileana Ramona Barac, George Balta, Mihail Zemba, Lacramioara Branduse, Claudia Mehedintu, Marian Burcea, Diana Andreea Barac, Daniel Constantin Branisteanu, Florian Balta
Article Number: 285
Published online on: 26 January 2021

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Article

Overexpression of Survivin‑1, TAG‑72 and HERC5 in patients diagnosed with hepatocellular carcinoma in the Black Sea coast geographical area

Andra-Iulia Suceveanu, Ioan Sergiu Micu, Gabriela-Izabela Baltatescu, Lucian Cristian Petcu, Nicolae Dobrin, Costel Brinzan, Cornelia Nitipir, Laura Mazilu, Florin Botea, Vlad Herlea, Felix Voinea, Adrian Paul Suceveanu
Article Number: 284
Published online on: 26 January 2021

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Article

Association between vascular comorbidity and glaucoma progression: A four-year observational study

Ana Maria Dascalu, Daniela Stana, Vanesa Andrada Nicolae, Catalin Cirstoveanu, Geta Vancea, Dragos Serban, Bogdan Socea
Article Number: 283
Published online on: 26 January 2021

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Review Open Access

Management of acute intradialytic cardiovascular complications: Updated overview (Review)

Delia Timofte, Maria-Daniela Tanasescu, Daniela Gabriela Balan, Adrian Tulin, Ovidiu Stiru, Ileana Adela Vacaroiu, Andrada Mihai, Cristian Constantin Popa, Cristina-Ileana Cosconel, Mihaly Enyedi, Daniela Miricescu, Raluca Ioana Papacocea, Dorin Ionescu
Article Number: 282
Published online on: 26 January 2021

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Case Report

Colchicine in the treatment of refractory aphthous ulcerations: Review of the literature and two case reports

Mihaela Paula Toader, Irina Mihaela Esanu, Tatiana Taranu, Madalina Mocanu, Stefan Toader
Article Number: 281
Published online on: 25 January 2021

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Article

Primary autoimmune neutropenia of infancy and childhood in a cohort of patients from western Romania

Cristian Jinca, Margit Serban, Emilia Ursu, Andrei Munteanu, Smaranda Arghirescu
Article Number: 280
Published online on: 25 January 2021

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Article

SARS‑CoV‑2 infection and diabetes mellitus: A North Eastern Romanian experience

Carmen Manciuc, Dragos Nemescu, Andrei Vata, Georgiana Alexandra Lacatusu
Article Number: 279
Published online on: 25 January 2021

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Review

Delivery and breastfeeding in pregnant patients with COVID‑19 (Review)

Mihai Cristian Dumitrascu, Monica Mihaela Cirstoiu, Adina-Elena Nenciu, Aida  Petca, Florica Sandru, Razvan-Cosmin Petca, Catalin George Nenciu
Article Number: 278
Published online on: 25 January 2021

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Article Open Access

Role of adjunctive therapy with subantimicrobial doses of doxycycline in glycemic control (HbA1c) in patients with diabetes and endo‑periodontal lesions to prevent sinus complications

Anamaria Zaharescu, Ioana Mârțu, Alexandru-Ionuț Luchian, Maria-Alexandra Mârțu, Irina-Georgeta Șufaru, Cristian Mârțu, Sorina-Mihaela Solomon
Article Number: 277
Published online on: 25 January 2021

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Review Open Access

Current perspectives in treating negative symptoms of schizophrenia: A narrative review (Review)

Octavia O. Căpățînă, Ioana V. Micluția, Mihaela Fadgyas-Stănculete
Article Number: 276
Published online on: 25 January 2021

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Review

Urban allergy review: Allergic rhinitis and asthma with plane tree sensitization (Review)

Daniela Vrinceanu, Ovidiu Nicolae Berghi, Romica Cergan, Mihai Dumitru, Radu Constantin Ciuluvica, Calin Giurcaneanu, Adriana Neagos
Article Number: 275
Published online on: 25 January 2021

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Article

Enterically transmitted hepatitis in the third millennium in northeastern Romania

Ioana Florina Mihai, Carmen Manciuc, Ioana Maria Hunea, Georgiana Alexandra Lacatusu, Georgiana Enache Leonte, Stefana Luca, Ioana Alina Harja‑Αlexa, Andrei Vata, Mihaela Catalina Luca
Article Number: 274
Published online on: 25 January 2021

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Review Open Access

Ultrasonography of the larynx: Novel use during the SARS‑CoV‑2 pandemic (Review)

Romica Cergan, Mihai Dumitru, Daniela Vrinceanu, Adriana Neagos, Ionut Isaia Jeican, Radu Constantin Ciuluvica
Article Number: 273
Published online on: 25 January 2021

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Review

Neurobiology of sleep (Review)

Cristian Falup‑Pecurariu, Ștefania Diaconu, Diana Țînț, Oana Falup‑Pecurariu
Article Number: 272
Published online on: 25 January 2021

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Review Open Access

A multidisciplinary approach to the management of liver disease and alcohol disorders in psychiatric settings (Review)

Simona Trifu, Andrian Țîbîrnă, Radu-Virgil Costea, Alexandra Popescu
Article Number: 271
Published online on: 25 January 2021

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Article

Heterogeneity of antigenic constellation in human hepatocellular carcinoma

Mihai Ceausu, Bogdan Socea, Dragos Serban, Cătălin   Gabriel Smarandache, Dragoş Predescu, Nicolae Bacalbaşa, Iulian Slavu, Adrian  Tulin, Lucian Alecu, Zenaida Ceauşu
Article Number: 270
Published online on: 25 January 2021

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Article

Fibroblast involvement in cardiac remodeling and repair under ischemic conditions

Zenaida Ceauşu, Bogdan Socea, Mariana Costache, Dragoş Predescu, Dragoş Şerban, Cătălin G. Smarandache, Irina Pacu, Haradja Horaţiu Alexandru, Ana Maria Daviţoiu, Florentina Jacotă‑Alexe, Cătălin Cîrstoveanu, Mihai C.T. Dimitriu, Liana Pleş, Mihai Ceauşu
Article Number: 269
Published online on: 25 January 2021

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Article

Breast cancer mortality gaps in Romanian women compared to the EU after 10 years of accession: Is breast cancer screening a priority for action in Romania? (Review of the Statistics)

Florentina Furtunescu, Roxana Elena Bohiltea, Silviu Voinea, Tiberiu Augustin Georgescu, Octavian Munteanu, Adrian Neacsu, Corina Silvia Pop
Article Number: 268
Published online on: 25 January 2021

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Article

A finite element analysis for predicting outcomes of cemented total knee arthroplasty

Nicolae Gheorghiu, Bogdan Socea, Mihai C.T. Dimitriu, Nicolae Bacalbasa, Gabriel Stan, Horia Orban
Article Number: 267
Published online on: 25 January 2021

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Review Open Access

Kidney aging process and the management of the elderly patient with renal impairment (Review)

Raluca Ioana Papacocea, Delia Timofte, Maria-Daniela Tanasescu, Andra-Elena Balcangiu-Stroescu, Daniela Gabriela Balan, Adrian Tulin, Ovidiu Stiru, Ileana Adela Vacaroiu, Andrada Mihai, Cristian Constantin Popa, Cristina-Ileana Cosconel, Mihaly Enyedi, Daniela Miricescu, Laura Raducu, Dorin Ionescu
Article Number: 266
Published online on: 25 January 2021

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Review Open Access

Therapeutic plasma exchange as a first‑choice therapy for axonal Guillain‑Barré syndrome: A case‑based review of the literature (Review)

Adina Stoian, Georgiana Șerban, Zoltan Bajko, Sebastian Andone, Oana Mosora, Adrian Bălașa
Article Number: 265
Published online on: 25 January 2021

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Article Open Access

Plasma ghrelin, adiponectin and leptin levels in obese rats with type 2 diabetes mellitus after sleeve gastrectomy and gastric plication

Laurian Stoica, Ramona Gadea, Dan-Bogdan Navolan, Fulger Lazar, Ciprian Duta, Dana Stoian, Cristi Tarta, Flavius Olaru, Alexandru Isaic, Amadeus Dobrescu
Article Number: 264
Published online on: 25 January 2021

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Review Open Access

Multifactorial expression of IL‑6 with update on COVID‑19 and the therapeutic strategies of its blockade (Review)

Elena Niculet, Valentin Chioncel, Alina M. Elisei, Magdalena Miulescu, Olimpia D. Buzia, Lawrence C. Nwabudike, Mihaela Craescu, Miruna Draganescu, Florin Bujoreanu, Elisabeta Marinescu, Manuela Arbune, Diana Sabina Radaschin, Carmen Bobeica, Aurel Nechita, Alin L. Tatu
Article Number: 263
Published online on: 25 January 2021

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Article Open Access

Evaluation of Vibrant® Soundbridge™ positioning and results with laser doppler vibrometry and the finite element model

Horia Mocanu, Matthias Bornitz, Nicoloz Lasurashvili, Thomas Zahnert
Article Number: 262
Published online on: 25 January 2021

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Article

Inherited thrombophilia is significantly associated with severe preeclampsia

Roxana Elena Bohiltea, Monica Mihaela Cirstoiu, Natalia Turcan, Anca Pantea Stoian, Corina-Aurelia Zugravu, Octavian Munteanu, Luciana Valentina Arsene, Bodean Oana, Adrian Neacsu, Florentina Furtunescu
Article Number: 261
Published online on: 25 January 2021

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Article Open Access

Long‑term histological results of ossicular chain reconstruction using bioceramic implants

Horia Mocanu, Adela-Ioana Mocanu, Ana Miruna Drăgoi, Marian Rădulescu
Article Number: 260
Published online on: 25 January 2021

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Article

Basic biochemical and hematological parameters in perinatal asphyxia and their correlation with hypoxic ischemic encephalopathy

Andrei Ioan Munteanu, Aniko-Maria Manea, Cristian Marius Jinca, Marioara Boia
Article Number: 259
Published online on: 25 January 2021

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Review

Perspectives of gold nanoparticles and their applications in pancreatic cancer (Review)

Anamaria Magdalena Tomşa, Andreea Liana Răchişan, Andreea Alexandra Aldea, Lorena Ciumărnean
Article Number: 258
Published online on: 25 January 2021

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Article

MicroRNA‑129‑5p promotes proliferation and metastasis of hepatocellular carcinoma by regulating the BMP2 gene

Zengyao Liu, Jiefei Sun, Xiaochun Wang, Zhenyuan Cao
Article Number: 257
Published online on: 25 January 2021

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Article Open Access

Double‑lobectomy in a steatotic liver transplantation rat model

Lin Fan, Zhen Fu, Yan Xiong, Shaojun Ye, Yanfeng Wang, Guizhu Peng, Qifa Ye
Article Number: 256
Published online on: 25 January 2021

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Article Open Access

MicroRNA‑34b‑5p inhibits proliferation, stemness, migration and invasion of retinoblastoma cells via Notch signaling

Shurong Zhang, Zhe Cui
Article Number: 255
Published online on: 25 January 2021

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Article Open Access

Diagnostic value and prognostic significance of CTRP9 combined with pentraxin‑3 in acute coronary syndrome

Na Jiang, Shulong Zhou, Guanglei Wang, Ningning Jiang, Huaixin Wang, Feng Zhao
Article Number: 254
Published online on: 25 January 2021

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Article

HSP70 expression before and after treatment and its clinical value in patients with acute angle‑closure glaucoma

Hong Chen, Aijun Tian, Yixiang Wu, Rongrong Li, Ruijuan Han, Xiaowei Xu, Sumian Cheng
Article Number: 253
Published online on: 25 January 2021

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Article Open Access

4‑Methoxybenzylalcohol protects brain microvascular endothelial cells against oxygen‑glucose deprivation/reperfusion‑induced injury via activation of the PI3K/AKT signaling pathway

Qing Lin, Weili Wang, Liping Yang, Xiaohua Duan
Article Number: 252
Published online on: 24 January 2021

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Article Open Access

Preventive and therapeutic significance of octreotide combined with lansoprazole on post‑ERCP pancreatitis and its effect on serum amylase, inflammatory factors and immune function

Zhiliang Chen, Hong Fu, Jianfeng Fang, Jianhui Yang, Xin Zhu, Bingxiang Cheng, Tiannv Ding
Article Number: 251
Published online on: 22 January 2021

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Article Open Access

Correlations of cardiac function with inflammation, oxidative stress and anemia in patients with uremia

Heping Zhang, Lei Fan, Huawei Liao, Lirong Tu, Jie Zhang, Dan Xu, Jiangchao Feng
Article Number: 250
Published online on: 22 January 2021

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Article Open Access

High expression of PIG11 correlates with poor prognosis in gastric cancer

Juan Gu, Shu Zhang, Xin He, Sufang Chen, Yan Wang
Article Number: 249
Published online on: 22 January 2021

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Article Open Access

ER stress preconditioning ameliorates liver damage after hemorrhagic shock and reperfusion

David Peter Obert, Alexander Karl Wolpert, Nathan Lewis Grimm, Sebastian Korff
Article Number: 248
Published online on: 22 January 2021

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Article

Prognostic value of using glucosylceramide synthase and cytochrome P450 family 1 subfamily A1 expression levels for patients with triple‑negative breast cancer following neoadjuvant chemotherapy

Jiannan Liu, Shuhua Wang, Congcong Wang, Xiangshuo Kong, Ping Sun
Article Number: 247
Published online on: 22 January 2021

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Case Report

Successful treatment of Gaucher disease type 1 by enzyme replacement therapy over a 10-year duration in a Japanese pediatric patient: A case report

Yuji Oto, Takeshi Inoue, So Nagai, Shinichiro Tanaka, Hisashi Itabashi, Masahisa Shiraisihi, Akihisa Nitta, Nobuyuki Murakami, Hiroyuki Ida, Tomoyo Matsubara
Article Number: 246
Published online on: 22 January 2021

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Article Open Access

Improving motor function after chronic stroke by interactive gaming with a redesigned MR‑compatible hand training device

Loukas G. Astrakas, Gianluca De Novi, Mark P. Ottensmeyer, Christian Pusatere, Shasha Li, Michael A. Moskowitz, A. Aria Tzika
Article Number: 245
Published online on: 22 January 2021

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Review Open Access

COVID‑19 and its consequences on mental health (Review)

Konstantinos Tsamakis, Dimitrios Tsiptsios, Andreas Ouranidis, Christoph Mueller, Dimitrios Schizas, Christos Terniotis, Nikolaos Nikolakakis, Georgios Tyros, Stylianos Kympouropoulos, Andreas Lazaris, Demetrios A. Spandidos, Nikolaos Smyrnis, Emmanouil Rizos
Article Number: 244
Published online on: 22 January 2021

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Review Open Access

Ovarian endometriosis, a precursor of ovarian cancer: Histological aspects, gene expression and microRNA alterations (Review)

Adriana Ioana Gaia‑Oltean, Cornelia Braicu, Diana Gulei, Razvan Ciortea, Dan Mihu, Horace Roman, Alexandru Irimie, Ioana Berindan‑Neagoe
Article Number: 243
Published online on: 22 January 2021

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Article Open Access

Discovering pathways in benign prostate hyperplasia: A functional genomics pilot study

Zheling Chen, Minyao Ge
Article Number: 242
Published online on: 22 January 2021

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Article Open Access

Inhibition of heat shock protein 90 alleviates cholestatic liver injury by decreasing IL‑1β and IL‑18 expression

Chenhao Tong, Jiandong Li, Weiguo Lin, Wenda Cen, Weiguang Zhang, Zhiyang Zhu, Baochun Lu, Jianhua Yu
Article Number: 241
Published online on: 21 January 2021

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Review Open Access

Experimental models in peritoneal dialysis (Review)

Bo Yang, Mengmeng Wang, Xue Tong, Ghada Ankawi, Lin Sun, Hongtao Yang
Article Number: 240
Published online on: 21 January 2021

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Article Open Access

Circular RNA expression profile in human primary multiple intracranial aneurysm

Huimin Cao, Jia Chen, Xiaoyan Lai, Tianqin Liu, Ping Qiu, Shuanglin Que, Yanming Huang
Article Number: 239
Published online on: 21 January 2021

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Article Open Access

Sodium hydrosulfide alleviates dexamethasone‑induced cell senescence and dysfunction through targeting the miR‑22/sirt1 pathway in osteoblastic MC3T3‑E1 cells

Peng Li, Wei-Wei Mao, Shuai Zhang, Liang Zhang, Zhi-Rong Chen, Zhi-Dong Lu
Article Number: 238
Published online on: 21 January 2021

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Article Open Access

Risk factors for respiratory assistance in premature infants

Hai-Xin Li, Cai-Jie Gao, Shan Cheng, Zhi-Lei Mao, Huai-Yan Wang
Article Number: 237
Published online on: 21 January 2021

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Article Open Access

Decreased expression of serum semaphorin 3B is associated with poor prognosis of patients with hepatocellular carcinoma

Guang-Zhen Li, Di Shen, Guang-Hong Li, Meng Wei, Li-Jie Zheng, Zeng-Li Liu, Rong-Qi Sun, Shao-Jun Zhou, Zong-Li Zhang, Yan-Chao Gao
Article Number: 236
Published online on: 21 January 2021

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Article Open Access

MicroRNA‑598 inhibits the growth of triple negative breast cancer cells by targeting JAG1

Guohui Han, Xiangdong Bai, Hongchuan Jiang, Qiang He
Article Number: 235
Published online on: 21 January 2021

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Article Open Access

Long non‑coding RNA cyclin‑dependent kinase inhibitor 2B antisense ribonucleic acid 1 is associated with in‑stent restenosis and promotes human carotid artery smooth muscle cell proliferation and migration by sponging miR‑143‑3p

Huanhuan Ma, Aiqin Dong
Article Number: 234
Published online on: 21 January 2021

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Article Open Access

Pomelo peel oil alleviates cerebral NLRP3 inflammasome activation in a cardiopulmonary resuscitation rat model

Xin-Sen Zou, Lu Xie, Wen-Yan Wang, Gao-Yang Zhao, Xin-Yue Tian, Meng-Hua Chen
Article Number: 233
Published online on: 21 January 2021

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Article Open Access

Long non‑coding RNA MIAT promotes the proliferation and invasion of laryngeal squamous cell carcinoma cells by sponging microRNA‑613

Fucun Song, Yang Yang, Jixiang Liu
Article Number: 232
Published online on: 21 January 2021

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Review Open Access

Challenges of phototherapy for neonatal hyperbilirubinemia (Review)

Juan Wang, Genxin Guo, Aimin Li, Wen-Qi Cai, Xianwang Wang
Article Number: 231
Published online on: 20 January 2021

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Article Open Access

MicroRNA‑1323 serves as a biomarker in gestational diabetes mellitus and aggravates high glucose‑induced inhibition of trophoblast cell viability by suppressing TP53INP1

Lijun Liu, Jun Zhang, Yujuan Liu
Article Number: 230
Published online on: 20 January 2021

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MicroRNA‑489‑3p plays a significant role in congenital hypothyroidism through regulating neuronal cell apoptosis via targeting translationally controlled tumor protein 1

Qin Liu, Yuehong Li, Yong Zhou
Article Number: 229
Published online on: 20 January 2021

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Effects of melatonin on protecting against lung injury (Review)

Weiwei Wang, Ju Gao
Article Number: 228
Published online on: 20 January 2021

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Recombinant interleukin-2 stimulates lymphocyte recovery in patients with severe COVID-19

Meng-En Zhu, Qian Wang, Shaoqiong Zhou, Bin Wang, Li Ke, Ping He
Article Number: 227
Published online on: 18 January 2021

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Novel applications of platelet concentrates in tissue regeneration (Review)

Zhen-Yu Ding, Ying Tan, Qian Peng, Jun Zuo, Ning Li
Article Number: 226
Published online on: 18 January 2021

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Quantitative T2 mapping of rats with chronic hepatitis

Xiaofeng Wang, Yan Hu, Xin Lu, Yu Cai, Jian Shu
Article Number: 225
Published online on: 18 January 2021

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Inhibition of the mevalonate pathway improves myocardial fibrosis

Huifeng Xu, Yi Shen, Chenyu Liang, Haifeng Wang, Junling Huang, Pengcheng Xue, Ming Luo
Article Number: 224
Published online on: 18 January 2021

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Review Open Access

Emerging recognition of the complement system in hepatic ischemia/reperfusion injury, liver regeneration and recovery (Review)

Zhi-Gao Hu, Yi Zhou, Cheng-Jie Lin, Guan-Dou Yuan, Song-Qing He
Article Number: 223
Published online on: 18 January 2021

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Effects of Streptococcus thermophilus on anterior cruciate ligament transection-induced early osteoarthritis in rats

Yen-You Lin, Nan-Fu Chen, San-Nan Yang, Yen-Hsuan Jean, Hsiao-Mei Kuo, Pei-Chin Chen, Chien-Wei Feng, Yu-Wei Liu, Yu-Cheng Lai, Zhi-Hong Wen
Article Number: 222
Published online on: 18 January 2021

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Phenoxythiophene sulfonamide compound B355252 protects neuronal cells against glutamate‑induced excitotoxicity by attenuating mitochondrial fission and the nuclear translocation of AIF

Yuxin Zhang, Nailya S. Gliyazova, P. Andy Li, Gordon Ibeanu
Article Number: 221
Published online on: 18 January 2021

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Schizandrin B attenuates hypoxia/reoxygenation injury in H9c2 cells by activating the AMPK/Nrf2 signaling pathway

Bo Zhao, Guang-Ping Li, Jian-Jun Peng, Li-Hui Ren, Li-Cheng Lei, Hui-Ming Ye, Zuo-Yan Wang, Sheng Zhao
Article Number: 220
Published online on: 18 January 2021

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LMTK2 regulates inflammation in lipopolysaccharide‑stimulated BV2 cells

Qianyun Rui, Shugang Cao, Xiaozhu Wang, Xiaoyu Duan, Xinyi  Iao, Wanli Dong, Qi Fang, Xueguang Zhang, Qun Xue
Article Number: 219
Published online on: 18 January 2021

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miR‑155 promotes proliferation and epithelial‑mesenchymal transition of MCF‑7 cells

Xiaoyan Liu, Yongjun Li, Zhuo Li, Tian Hou
Article Number: 218
Published online on: 15 January 2021

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Efficacy and tolerability of sitagliptin and metformin compared with insulin as an initial therapy for newly diagnosed diabetic patients with severe hyperglycaemia

Mingqian He, Mei Deng, Jingya Wang, Pengxia Fan, Yue Wang, Xinrui Zhao, Yizhi He, Bingyin Shi, Jing Sui
Article Number: 217
Published online on: 15 January 2021

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Serum IL‑21 levels predict HBeAg decline during rescue therapy in patients with partial response to nucleos(t)ide analogues

Yue Li, Calvin Q. Pan, Shibo Ji, Gaiqin Yan, Jun Cheng, Shunai Liu, Huichun Xing
Article Number: 216
Published online on: 15 January 2021

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Insulin-like growth factor-1 improves postoperative cognitive dysfunction following splenectomy in aged rats

Bin Wang, Xu Lin, Jiahui Zhou, Chunhui Xie, Chuan Li, Rui Dong, Gaofeng Zhang, Xiaopeng Sun, Mingshan Wang, Yanlin Bi
Article Number: 215
Published online on: 15 January 2021

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The vasodilatory mechanism of nitric oxide and hydrogen sulfide in the human mesenteric artery in patients with colorectal cancer

Awat Y. Hassan, Ismail M. Maulood, Abbas Salihi
Article Number: 214
Published online on: 15 January 2021

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A systematic review and meta‑analysis of minimally invasive vs. standard percutaneous nephrolithotomy in the surgical management of renal stones

Binbin Jiao, Zhenkai Luo, Tao Huang, Guan Zhang, Jiang Yu
Article Number: 213
Published online on: 15 January 2021

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miR‑142‑3p reduces the viability of human cervical cancer cells by negatively regulating the cytoplasmic localization of HMGB1

Hui Dong, Jie Song
Article Number: 212
Published online on: 14 January 2021

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Lidocaine attenuates CFA‑induced inflammatory pain in rats by regulating the MAPK/ERK/NF‑κB signaling pathway

Shuli Zhang, Yan Li, Yingjun Tu
Article Number: 211
Published online on: 14 January 2021

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Umbilical cord‑derived mesenchymal stem cells exert anti‑fibrotic action on hypertrophic scar‑derived fibroblasts in co‑culture by inhibiting the activation of the TGF β1/Smad3 pathway

Xianglong Meng, Xinxin Gao, Xinxin Chen, Jiaao Yu
Article Number: 210
Published online on: 14 January 2021

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T‑regulatory cells from patients with rheumatoid arthritis retain suppressor functions in vitro

Daniil Shevyrev, Valeriy Tereshchenko, Vladimir Kozlov, Alexey Sizikov, Oksana Chumasova, Veroniсa Koksharova
Article Number: 209
Published online on: 14 January 2021

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NOD‑like receptor X1, tumor necrosis factor receptor‑associated factor 6 and NF‑κB are associated with clinicopathological characteristics in gastric cancer

Zhe Fan, Jiyong Pan, Hai Wang, Yewei Zhang
Article Number: 208
Published online on: 14 January 2021

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Dexpanthenol reduces fibrosis and aids repair following nerve laceration and neurorrhaphy

Gokhan Karahan, Huseyin Kaya, Recep Selçuk Eyceyurt, Mumin Alper Erdogan, Gurkan Yigitturk, Oytun Erbas
Article Number: 207
Published online on: 13 January 2021

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Effects of 10 Hz repetitive transcranial magnetic stimulation of the right dorsolateral prefrontal cortex in the vegetative state

Xin Ge, Yue Zhang, Tian Xin, Xue Luan
Article Number: 206
Published online on: 13 January 2021

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Detection of microRNA‑33a‑5p in serum, urine and renal tissue of patients with IgA nephropathy

Lihua Liu, Aosong Duan, Qiaoyan Guo, Guangdong Sun, Wenpeng Cui, Xuehong Lu, Hongyu Yu, Ping Luo
Article Number: 205
Published online on: 11 January 2021

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HSP60 participates in the anti‑glioma effects of curcumin

Fengchen Bi, Junyan Wang, Xiaomin Zheng, Jingjing Xiao, Chai Zhi, Jinhai Gu, Yumei Zhang, Juan Li, Zhenhua Miao, Yin Wang, Yunhong Li
Article Number: 204
Published online on: 11 January 2021

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Apoptosis inhibition is involved in improvement of sevoflurane‑induced cognitive impairment following normobaric hyperoxia preconditioning in aged rats

Ying Wang, Chun-Ping Yin, Yan-Lei Tai, Zi-Jun Zhao, Zhi-Yong Hou, Qiu-Jun Wang
Article Number: 203
Published online on: 11 January 2021

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Article

Curcumin suppresses the proliferation of oral squamous cell carcinoma through a specificity protein 1/nuclear factor‑κB‑dependent pathway

Tian Liu, Tian Long, Haosen Li
Article Number: 202
Published online on: 11 January 2021

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Mycoplasma pneumoniae pneumonia with pulmonary embolism: A study on pediatric cases in Jilin province of China

Chu-Qiao Sheng, Chun-Feng Yang, Yu Ao, Zhi-Yue Zhao, Yu-Mei Li
Article Number: 201
Published online on: 11 January 2021

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Case Report Open Access

Visual impairment in immunoglobulin G4‑related disease: A case report

Xue Wang, Xuren Sun, Ran Ao, Zilu Zeng, Dan Li, Yiling Li
Article Number: 200
Published online on: 11 January 2021

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miR‑361‑5p regulates ovarian cancer cell proliferation and apoptosis by targeting TRAF3

Jianmei Ling, Panwen He
Article Number: 199
Published online on: 11 January 2021

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Efficacy of bupivacaine infiltration for controlling post‑tonsillectomy pain, duration of surgery and post‑operative morbidities: A systematic review and meta‑analysis

Juan Wang, Ning Wang, Fanghua Gong
Article Number: 198
Published online on: 08 January 2021

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Shuxuetong injection simultaneously ameliorates dexamethasone‑driven vascular calcification and osteoporosis

Zhe Xu, Xiaoguang Liu, Yanqing Li, Hongliang Gao, Tao He, Chunlei Zhang, Wei Hao, Xu Teng
Article Number: 197
Published online on: 08 January 2021

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Influence of esophageal morphology on the clinical efficacy of peroral endoscopic myotomy in treating advanced achalasia cardia

Dan Liu, Yue-Yuan Liu, Jia-Xin Chen, Lei Song, Yang-Yang Zhou, Saif Ullah, Li-Xia Zhao, Bin Hai, Qing-Fen Zheng, Dong-Ying Li, De-Zhi He, Bing-Rong Liu
Article Number: 196
Published online on: 08 January 2021

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Synergistic inhibitory effects of low‑dose decitabine in combination with bortezomib in the AML cell line Kasumi‑1

Vassiliki Mpakou, Aris Spathis, Anthi Bouhla, Efthimia Mpazani, Sotirios Papageorgiou, Konstantinos Gkontopoulos, Eirini Glezou, Thomas Thomopoulos, Periklis Foukas, Vasiliki Pappa
Article Number: 195
Published online on: 08 January 2021

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Ergosterol limits osteoarthritis development and progression through activation of Nrf2 signaling

Dawei Cai, Huyong Yan, Jun Liu, Sichun Chen, Longhai Jiang, Xiaoxu Wang, Jian Qin
Article Number: 194
Published online on: 08 January 2021

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Case Report

Somatically acquired mutations in primary myelofibrosis: A case report and meta‑analysis

Yongming Xia, Qingxiao Hong, Zhibin Gao, Shijun Wang, Shiwei Duan
Article Number: 193
Published online on: 07 January 2021

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MicroRNA‑615‑5p regulates the proliferation and apoptosis of breast cancer cells by targeting HSF1

Kaisheng Liu, Rong Ma
Article Number: 192
Published online on: 07 January 2021

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Validation of a novel UPLC‑HRMS method for human whole‑blood cyclosporine and comparison with a CMIA immunoassay

Xiaoxue Wang, Wei Qin, Wenqian Chen, Huifang Liu, Dan Zhang, Xianglin Zhang, Pengmei Li
Article Number: 191
Published online on: 07 January 2021

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Mechanism of circadian regulation of the NRF2/ARE pathway in renal ischemia‑reperfusion

Qian Sun, Cheng Zeng, Li Du, Chong Dong
Article Number: 190
Published online on: 07 January 2021

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Case Report Open Access

Role of ultrasound and CT in the early diagnosis and surgical treatment of primary sternal osteomyelitis caused by Salmonella: Case reports

Mengjiao Qian, Jing Wang, Jun Li, Sibo Wang, Zhongyin Wang, Xiao Chen, Haibo Ou, Yuanzhong Liang, Xuguan Peng
Article Number: 189
Published online on: 07 January 2021

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Lactobacillus spp. reduces ethanol‑induced liver oxidative stress and inflammation in a mouse model of alcoholic steatohepatitis

Pei-Shan Hsieh, Ching-Wei Chen, Yi-Wei Kuo, Hsieh-Hsun Ho
Article Number: 188
Published online on: 07 January 2021

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Abnormal expression of TRIAP1 and its role in gestational diabetes mellitus‑related pancreatic β cells

Linxia Li, Kaihan Yang, Fang Ye, Yi Xu, Lili Cao, Jia Sheng
Article Number: 187
Published online on: 07 January 2021

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Sulforaphane protects human umbilical vein endothelial cells from oxidative stress via the miR‑34a/SIRT1 axis by upregulating nuclear factor erythroid‑2‑related factor 2

Tao Li, Qi Pang, Yongbin Liu, Ming Bai, Yu Peng, Zheng Zhang
Article Number: 186
Published online on: 07 January 2021

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Combination of the neutrophil to lymphocyte ratio and serum toluidine red unheated serum test titer as a predictor of neurosyphilis in HIV‑negative patients

Caifeng He, Xianjin Shang, Wenbei Liu, Shouyun Hang, Jingtao Chen, Chao Ci
Article Number: 185
Published online on: 07 January 2021

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Effects of transcutaneous electrical acupoint stimulation on perioperative immune function and postoperative analgesia in patients undergoing radical mastectomy: A randomized controlled trial

Li Ao, Jinlin Shi, Yaowu Bai, Shan Zhang, Jianhui Gan
Article Number: 184
Published online on: 07 January 2021

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Experimental pretreatment with YES‑10®, a plant extract rich in scutellarin and chlorogenic acid, protects hippocampal neurons from ischemia/reperfusion injury via antioxidant role

Young Eun Park, Yoohun Noh, Dae Won Kim, Tae-Kyeong Lee, Ji Hyeon Ahn, Bora Kim, Jae-Chul Lee, Cheol Woo Park, Joon Ha Park, Jong Dai Kim, Young-Myeong Kim, Il Jun Kang, Ji-Won Lee, Sung-Su Kim, Moo-Ho Won
Article Number: 183
Published online on: 07 January 2021

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Application of a prediction model with laboratory indexes in the risk stratification of patients with COVID‑19

Jiru Ye, Xiaoqing Zhang, Feng Zhu, Yao Tang
Article Number: 182
Published online on: 05 January 2021

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FABP4 alleviates endoplasmic reticulum stress‑mediated ischemia‑reperfusion injury in PC12 cells via regulation of PPARγ

Xiao-Lan Yang, Jian-Hua Mi, Qing Dong
Article Number: 181
Published online on: 05 January 2021

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IOX1 protects from TGF‑β induced fibrosis in LX‑2 cells via the regulation of extracellular matrix protein expression

Tian Tian, Rujia Xie, Kaize Ding, Bing Han, Qin Yang, Xue Yang
Article Number: 180
Published online on: 05 January 2021

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miR‑206 serves an important role in polycystic ovary syndrome through modulating ovarian granulosa cell proliferation and apoptosis

Jie Zhou, Xuejing Jin, Zhumei Sheng, Zhifen Zhang
Article Number: 179
Published online on: 05 January 2021

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Changes and significance of hydrodynamic parameters in Budd‑Chiari syndrome with obstruction of the inferior vena cava prior to and after interventional therapy

Lulu Lyu, Peng Xu, Jie Ping, Chunfeng Hu, Kai Xu
Article Number: 178
Published online on: 05 January 2021

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July-2026 Volume 32 Issue 1

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Amplification of heterogeneous nuclear ribonucleoprotein A/B aids in immune infiltration regulation and breast cancer tumorigenesis

Jiachao Xu, Qian Han, Libin Chen, Min Yang, Jun Huang, Shanhong Lin, Shengmin Zhang
Article Number: 198
Published online on: 27 May 2026

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Retraction Open Access

[Retracted] Novel triazole analogs of apigenin‑7‑methyl ether exhibit potent antitumor activity against ovarian carcinoma cells via the induction of mitochondrial‑mediated apoptosis

Yuyan Qi, Zhaoxia Ding, Yushuang Yao, Dehua Ma, Feifei Ren, Hongjuan Yang, Aiping Chen
Article Number: 197
Published online on: 26 May 2026

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Meta‑analysis of the efficacy of reverse total shoulder arthroplasty and open reduction and internal fixation in the treatment of proximal humerus fractures

Yuan Li, Meng-Xuan Niu, Fang-Zheng He, Xin Qin, Wei-Wei Wang, Peng-Fei Han
Article Number: 196
Published online on: 21 May 2026

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Fatty acid‑activated proton transporter SR4 prevents hepatic steatosis and metabolic alterations in diabetic mice by improving mitochondria function, energy balance and oxidative stress

James Figarola, Jyotsana Singhal, Sharad Singhal
Article Number: 195
Published online on: 20 May 2026

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Expression of Concern Open Access

[Expression of Concern] Endogenous Nampt upregulation is associated with diabetic nephropathy inflammatory‑fibrosis through the NF‑κB p65 and Sirt1 pathway; NMN alleviates diabetic nephropathy inflammatory‑fibrosis by inhibiting endogenous Nampt

Ye Chen, Yuzhen Liang, Tingting Hu, Riming Wei, Congjie Cai, Ping Wang, Lingyu Wang, Wei Qiao, Leping Feng
Article Number: 194
Published online on: 20 May 2026

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Impact of vitamin D receptor gene variants on psoriasis vulgaris susceptibility and clinical phenotype in a Greek population

Polytimi Sidiropoulou, Martha Katsarou, Maria Papasavva, Annia Tsolakou, Akylas Fotiadis, Demetrios A. Spandidos, Natalia Rompoti, Irene Stefanaki, Alexander J. Stratigos, Nikolaos Drakoulis, Electra Nicolaidou
Article Number: 193
Published online on: 19 May 2026

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[Retracted] Resistin increases the expression of NOD2 in mouse monocytes

Yi Ren, Taomei Wan, Zhicai Zuo, Hengmin Cui, Xi Peng, Jing Fang, Junliang Deng, Yanchun Hu, Shuming Yu, Liuhong Shen, Xiaoping Ma, Ya Wang, Zhihua Ren
Article Number: 192
Published online on: 18 May 2026

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Case Report Open Access

Morphological analysis of bronchoalveolar lavage fluid in diagnosing pulmonary aspergilloma in a patient with rheumatoid arthritis: A case report

Yuli Zhou, Yuyi Lai, Fuxian Zhou, Xinxin Wang, Xiao He, Juan Jin, Ruikai Zhang
Article Number: 191
Published online on: 14 May 2026

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Case Report Open Access

Intravenous leiomyomatosis of the uterus: A case report and literature review

Yuzhen Zhao, Fei Tian
Article Number: 190
Published online on: 14 May 2026

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3D‑Printed prosthesis for recurrent femoral metastasis with periprosthetic infection: A case report

Jiangbi Li, Yangjie Zhang, Jianping Kang, Changping Tian, Suolin Chen, Ya Ning, Haixia Li, Yanbin Xiao
Article Number: 189
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Targeting Sirt1 in a rat model of high‑fat diet‑induced non‑alcoholic fatty liver disease: Comparison of Gegen Qinlian decoction and resveratrol

Yi Guo, Jun-Xiang Li, Tang-You Mao, Wei-Han Zhao, Li-Juan Liu, Yun-Liang Wang
Article Number: 188
Published online on: 13 May 2026

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Glycolytic reprogramming in host response to Borrelia burgdorferi: A gene signature revealed by integrative bioinformatics analysis and machine learning

Yan Dong, Yantong Chen, Yanshuang Luo, Meng Liu, Chao Song, Xuesong Chen, Fusong Yang, Qingyi Luo, Guozhong Zhou
Article Number: 187
Published online on: 12 May 2026

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[Retracted]Oblongifolin C reverses GEM resistance via suppressing autophagy flux in bladder cancer cells

Zhilong Huang, Tingting Wang, Wenjun Xia, Qing Li, Xinlei Chen, Xiaoli Liu, Peng Wei, Wenping Xu, Meirong Lv
Article Number: 186
Published online on: 11 May 2026

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Genetic etiology and phenotypic characteristics of fetuses with 11q deletion syndrome (11q23.3‑q25)

Tong Zhang, Xiaoyi Cong, Zhenming Li, Xianzhen Cao, Liang Hu, Xiaojin Luo, Yanan Liu, Weiqiang Liu, Fengxiang Wei
Article Number: 185
Published online on: 08 May 2026

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CDX2‑UPK1B‑PIK3IP1‑PI3K/AKT signaling axis regulates gastric cancer cell invasion and migration and influences patient prognosis

Shaodong Zhong, Heng Zhang, Jin Huang
Article Number: 184
Published online on: 08 May 2026

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Modulation of the tumor microenvironment by incretins and glucagon: Metabolic and immune mechanisms (Review)

Min Hu, Chang-Jun Jiang, Cheng Yi
Article Number: 183
Published online on: 08 May 2026

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TPX2 as a prognostic biomarker and potential therapeutic target for malignant melanoma proliferation and metastasis

Fuqi Li, Ronghui Yang, Zhixian Wu
Article Number: 182
Published online on: 08 May 2026

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Review Open Access

Benefits and mechanisms of polysaccharides derived from traditional Chinese medicine for ulcerative colitis treatment (Review)

Yuebo Jia, Zheng Jiao, Lingshuo Bai, Gege Li, Lijian Pang
Article Number: 181
Published online on: 08 May 2026

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Retraction Open Access

[Retracted] Synergistic inhibition of leukemia WEHI‑3 cell growth by arsenic trioxide and Hedyotis diffusa Willd extract in vitro and in vivo

Yu-Jui Kuo, Yan-Jin Liu, Tzong-Der Way, Su-Yin Chiang, Jaung-Geng Lin, Jing-Gung Chung
Article Number: 180
Published online on: 29 April 2026

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August-2026 Volume 32 Issue 2

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Case Report Open Access

Immune‑related nephritis, ureteritis and cystitis secondary to immune checkpoint inhibitors: A case report and review of the literature

Guangquan Zhang, Silu Xu, Jing Wu, Qianqian Gao, Yanzhi Bi, Min Xiao
Article Number: 210
Published online on: 08 June 2026

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[Retracted] Acaricidal activity of extracts from Ligularia virgaurea against the Sarcoptes scabiei mite in vitro

Biao Luo, Fei Liao, Yanchun Hu, Xi Liu, Yajun He, Lei Wu, Hui Tan, Lijuan Luo, Yancheng Zhou, Quan Mo, Junliang Deng, Yahui Wei
Article Number: 209
Published online on: 08 June 2026

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Epithelioid fibrous histiocytoma of eyelid in children: A case report

Zheng Sun, Zhaoxia Zhai, Yutian Li, Peiyan Shi, Wei Cheng, Jinling Ge, Yanfei Li
Article Number: 208
Published online on: 05 June 2026

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Article

Stevens‑Johnson syndrome induced by fluoroquinolones in a patient with colon cancer: A case report and literature review

Yuan Zhou, Guangye Huang, Hongxia Li
Article Number: 207
Published online on: 04 June 2026

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Sotagliflozin ameliorates doxorubicin-induced cardiomyopathy by regulating inflammation and mitochondrial dysfunction through the AMPK/mTOR pathway

Haifeng Liu, Danye Han, Meiling Li
Article Number: 206
Published online on: 04 June 2026

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Integrated network pharmacology and serum metabolomics to reveal the protective mechanism of methanolic extract of BaiYangJie on cisplatin‑induced acute kidney injury in mice

Bin Xia, Jianglong Chen, Jinhui Wang, Dalong Li, Lixia Zhang, Jing Su, Xuan Ding, Yana Lv, Shifang Liu, Xue Zhang, Tianzhen Wan, Guang Li
Article Number: 205
Published online on: 04 June 2026

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Screening criteria for drainage-free patients after retroperitoneal laparoscopic adrenal tumor resection and their prospective validation study value

Yan Zhao, Yu-Xuan He, Hai-Tao Li, Jing-Yi Cao, Bing Zhong, Hui Zhou
Article Number: 204
Published online on: 04 June 2026

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[Retracted] Atorvastatin increases lipopolysaccharide‑induced expression of tumour necrosis factor‑α‑induced protein 8‑like 2 in RAW264.7 cells

Ming-Wei Liu, Mei-Xian Su, Wei Zhang, Li Wang, Chuan-Yun Qian
Article Number: 203
Published online on: 02 June 2026

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Case Report Open Access

LMNA c.1622G>A mutation and myopathic changes in a family with limb‑girdle muscular dystrophy: A case report

Yanling Zhu, Qiushi Wang, Tiefeng Zhang
Article Number: 202
Published online on: 02 June 2026

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Case Report Open Access

Optimizing management of immune checkpoint inhibitor‑induced inflammatory arthritis: A case series and literature review

Yuanyuan Wang, Yingmei Wen, Jinxiong Xia, Hongyan Feng, Fei Wu, Dafu Ye, Yanjun Gao, Qingqing Li, Yi Yao
Article Number: 201
Published online on: 29 May 2026

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Tumor Treating Fields modulate apoptotic and immune programs in T‑cell acute lymphoblastic leukemia cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 200
Published online on: 29 May 2026

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Case Report

Complete ureteral duplication with occult calculi: A case report

Haiyan Zheng, Li Wang, Rui Yang, Shenghao Niu, Faying Yang, Jiaxi Yao
Article Number: 199
Published online on: 29 May 2026

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