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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March-2021 Volume 21 Issue 3

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Impact Factor: 2.3

Article Open Access

Femtosecond‑LASIK outcomes using the VisuMax®‑MEL® 80 platform for hyperopia and hyperopic astigmatism refractive surgery

Bogdana Tăbăcaru, Horia Tudor Stanca, Ruxandra Angela Pîrvulescu, Simona Stanca, Ciprian Danielescu, Mihnea Munteanu, Cosmin Roșca, Adrian Cosmin Teodoru
Article Number: 288
Published online on: 26 January 2021

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Review

Thrombotic risk in antiphospholipidic syndrome: From hypothesis to current evidence (Review)

Claudia Mihaela Gavriș, Laurențiu Dănuț Nedelcu, Alina Mihaela Pascu
Article Number: 287
Published online on: 26 January 2021

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Article Open Access

Correlations of sialic acid with glycated hemoglobin A1c and glycemia in postmenopausal women with type‑2 diabetes mellitus

Octavian Gabriel Olaru, Gianina Ioana Constantin, Catalina Monica Pena
Article Number: 286
Published online on: 26 January 2021

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Article Open Access

Accelerated vs. conventional collagen cross‑linking for infectious keratitis

Ileana Ramona Barac, George Balta, Mihail Zemba, Lacramioara Branduse, Claudia Mehedintu, Marian Burcea, Diana Andreea Barac, Daniel Constantin Branisteanu, Florian Balta
Article Number: 285
Published online on: 26 January 2021

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Article

Overexpression of Survivin‑1, TAG‑72 and HERC5 in patients diagnosed with hepatocellular carcinoma in the Black Sea coast geographical area

Andra-Iulia Suceveanu, Ioan Sergiu Micu, Gabriela-Izabela Baltatescu, Lucian Cristian Petcu, Nicolae Dobrin, Costel Brinzan, Cornelia Nitipir, Laura Mazilu, Florin Botea, Vlad Herlea, Felix Voinea, Adrian Paul Suceveanu
Article Number: 284
Published online on: 26 January 2021

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Article

Association between vascular comorbidity and glaucoma progression: A four-year observational study

Ana Maria Dascalu, Daniela Stana, Vanesa Andrada Nicolae, Catalin Cirstoveanu, Geta Vancea, Dragos Serban, Bogdan Socea
Article Number: 283
Published online on: 26 January 2021

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Review Open Access

Management of acute intradialytic cardiovascular complications: Updated overview (Review)

Delia Timofte, Maria-Daniela Tanasescu, Daniela Gabriela Balan, Adrian Tulin, Ovidiu Stiru, Ileana Adela Vacaroiu, Andrada Mihai, Cristian Constantin Popa, Cristina-Ileana Cosconel, Mihaly Enyedi, Daniela Miricescu, Raluca Ioana Papacocea, Dorin Ionescu
Article Number: 282
Published online on: 26 January 2021

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Case Report

Colchicine in the treatment of refractory aphthous ulcerations: Review of the literature and two case reports

Mihaela Paula Toader, Irina Mihaela Esanu, Tatiana Taranu, Madalina Mocanu, Stefan Toader
Article Number: 281
Published online on: 25 January 2021

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Article

Primary autoimmune neutropenia of infancy and childhood in a cohort of patients from western Romania

Cristian Jinca, Margit Serban, Emilia Ursu, Andrei Munteanu, Smaranda Arghirescu
Article Number: 280
Published online on: 25 January 2021

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Article

SARS‑CoV‑2 infection and diabetes mellitus: A North Eastern Romanian experience

Carmen Manciuc, Dragos Nemescu, Andrei Vata, Georgiana Alexandra Lacatusu
Article Number: 279
Published online on: 25 January 2021

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Review

Delivery and breastfeeding in pregnant patients with COVID‑19 (Review)

Mihai Cristian Dumitrascu, Monica Mihaela Cirstoiu, Adina-Elena Nenciu, Aida  Petca, Florica Sandru, Razvan-Cosmin Petca, Catalin George Nenciu
Article Number: 278
Published online on: 25 January 2021

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Article Open Access

Role of adjunctive therapy with subantimicrobial doses of doxycycline in glycemic control (HbA1c) in patients with diabetes and endo‑periodontal lesions to prevent sinus complications

Anamaria Zaharescu, Ioana Mârțu, Alexandru-Ionuț Luchian, Maria-Alexandra Mârțu, Irina-Georgeta Șufaru, Cristian Mârțu, Sorina-Mihaela Solomon
Article Number: 277
Published online on: 25 January 2021

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Review Open Access

Current perspectives in treating negative symptoms of schizophrenia: A narrative review (Review)

Octavia O. Căpățînă, Ioana V. Micluția, Mihaela Fadgyas-Stănculete
Article Number: 276
Published online on: 25 January 2021

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Review

Urban allergy review: Allergic rhinitis and asthma with plane tree sensitization (Review)

Daniela Vrinceanu, Ovidiu Nicolae Berghi, Romica Cergan, Mihai Dumitru, Radu Constantin Ciuluvica, Calin Giurcaneanu, Adriana Neagos
Article Number: 275
Published online on: 25 January 2021

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Article

Enterically transmitted hepatitis in the third millennium in northeastern Romania

Ioana Florina Mihai, Carmen Manciuc, Ioana Maria Hunea, Georgiana Alexandra Lacatusu, Georgiana Enache Leonte, Stefana Luca, Ioana Alina Harja‑Αlexa, Andrei Vata, Mihaela Catalina Luca
Article Number: 274
Published online on: 25 January 2021

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Review Open Access

Ultrasonography of the larynx: Novel use during the SARS‑CoV‑2 pandemic (Review)

Romica Cergan, Mihai Dumitru, Daniela Vrinceanu, Adriana Neagos, Ionut Isaia Jeican, Radu Constantin Ciuluvica
Article Number: 273
Published online on: 25 January 2021

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Review

Neurobiology of sleep (Review)

Cristian Falup‑Pecurariu, Ștefania Diaconu, Diana Țînț, Oana Falup‑Pecurariu
Article Number: 272
Published online on: 25 January 2021

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Review Open Access

A multidisciplinary approach to the management of liver disease and alcohol disorders in psychiatric settings (Review)

Simona Trifu, Andrian Țîbîrnă, Radu-Virgil Costea, Alexandra Popescu
Article Number: 271
Published online on: 25 January 2021

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Article

Heterogeneity of antigenic constellation in human hepatocellular carcinoma

Mihai Ceausu, Bogdan Socea, Dragos Serban, Cătălin   Gabriel Smarandache, Dragoş Predescu, Nicolae Bacalbaşa, Iulian Slavu, Adrian  Tulin, Lucian Alecu, Zenaida Ceauşu
Article Number: 270
Published online on: 25 January 2021

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Article

Fibroblast involvement in cardiac remodeling and repair under ischemic conditions

Zenaida Ceauşu, Bogdan Socea, Mariana Costache, Dragoş Predescu, Dragoş Şerban, Cătălin G. Smarandache, Irina Pacu, Haradja Horaţiu Alexandru, Ana Maria Daviţoiu, Florentina Jacotă‑Alexe, Cătălin Cîrstoveanu, Mihai C.T. Dimitriu, Liana Pleş, Mihai Ceauşu
Article Number: 269
Published online on: 25 January 2021

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Article

Breast cancer mortality gaps in Romanian women compared to the EU after 10 years of accession: Is breast cancer screening a priority for action in Romania? (Review of the Statistics)

Florentina Furtunescu, Roxana Elena Bohiltea, Silviu Voinea, Tiberiu Augustin Georgescu, Octavian Munteanu, Adrian Neacsu, Corina Silvia Pop
Article Number: 268
Published online on: 25 January 2021

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Article

A finite element analysis for predicting outcomes of cemented total knee arthroplasty

Nicolae Gheorghiu, Bogdan Socea, Mihai C.T. Dimitriu, Nicolae Bacalbasa, Gabriel Stan, Horia Orban
Article Number: 267
Published online on: 25 January 2021

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Review Open Access

Kidney aging process and the management of the elderly patient with renal impairment (Review)

Raluca Ioana Papacocea, Delia Timofte, Maria-Daniela Tanasescu, Andra-Elena Balcangiu-Stroescu, Daniela Gabriela Balan, Adrian Tulin, Ovidiu Stiru, Ileana Adela Vacaroiu, Andrada Mihai, Cristian Constantin Popa, Cristina-Ileana Cosconel, Mihaly Enyedi, Daniela Miricescu, Laura Raducu, Dorin Ionescu
Article Number: 266
Published online on: 25 January 2021

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Review Open Access

Therapeutic plasma exchange as a first‑choice therapy for axonal Guillain‑Barré syndrome: A case‑based review of the literature (Review)

Adina Stoian, Georgiana Șerban, Zoltan Bajko, Sebastian Andone, Oana Mosora, Adrian Bălașa
Article Number: 265
Published online on: 25 January 2021

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Article Open Access

Plasma ghrelin, adiponectin and leptin levels in obese rats with type 2 diabetes mellitus after sleeve gastrectomy and gastric plication

Laurian Stoica, Ramona Gadea, Dan-Bogdan Navolan, Fulger Lazar, Ciprian Duta, Dana Stoian, Cristi Tarta, Flavius Olaru, Alexandru Isaic, Amadeus Dobrescu
Article Number: 264
Published online on: 25 January 2021

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Review Open Access

Multifactorial expression of IL‑6 with update on COVID‑19 and the therapeutic strategies of its blockade (Review)

Elena Niculet, Valentin Chioncel, Alina M. Elisei, Magdalena Miulescu, Olimpia D. Buzia, Lawrence C. Nwabudike, Mihaela Craescu, Miruna Draganescu, Florin Bujoreanu, Elisabeta Marinescu, Manuela Arbune, Diana Sabina Radaschin, Carmen Bobeica, Aurel Nechita, Alin L. Tatu
Article Number: 263
Published online on: 25 January 2021

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Article Open Access

Evaluation of Vibrant® Soundbridge™ positioning and results with laser doppler vibrometry and the finite element model

Horia Mocanu, Matthias Bornitz, Nicoloz Lasurashvili, Thomas Zahnert
Article Number: 262
Published online on: 25 January 2021

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Article

Inherited thrombophilia is significantly associated with severe preeclampsia

Roxana Elena Bohiltea, Monica Mihaela Cirstoiu, Natalia Turcan, Anca Pantea Stoian, Corina-Aurelia Zugravu, Octavian Munteanu, Luciana Valentina Arsene, Bodean Oana, Adrian Neacsu, Florentina Furtunescu
Article Number: 261
Published online on: 25 January 2021

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Article Open Access

Long‑term histological results of ossicular chain reconstruction using bioceramic implants

Horia Mocanu, Adela-Ioana Mocanu, Ana Miruna Drăgoi, Marian Rădulescu
Article Number: 260
Published online on: 25 January 2021

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Article

Basic biochemical and hematological parameters in perinatal asphyxia and their correlation with hypoxic ischemic encephalopathy

Andrei Ioan Munteanu, Aniko-Maria Manea, Cristian Marius Jinca, Marioara Boia
Article Number: 259
Published online on: 25 January 2021

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Review

Perspectives of gold nanoparticles and their applications in pancreatic cancer (Review)

Anamaria Magdalena Tomşa, Andreea Liana Răchişan, Andreea Alexandra Aldea, Lorena Ciumărnean
Article Number: 258
Published online on: 25 January 2021

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Article

MicroRNA‑129‑5p promotes proliferation and metastasis of hepatocellular carcinoma by regulating the BMP2 gene

Zengyao Liu, Jiefei Sun, Xiaochun Wang, Zhenyuan Cao
Article Number: 257
Published online on: 25 January 2021

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Article Open Access

Double‑lobectomy in a steatotic liver transplantation rat model

Lin Fan, Zhen Fu, Yan Xiong, Shaojun Ye, Yanfeng Wang, Guizhu Peng, Qifa Ye
Article Number: 256
Published online on: 25 January 2021

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Article Open Access

MicroRNA‑34b‑5p inhibits proliferation, stemness, migration and invasion of retinoblastoma cells via Notch signaling

Shurong Zhang, Zhe Cui
Article Number: 255
Published online on: 25 January 2021

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Article Open Access

Diagnostic value and prognostic significance of CTRP9 combined with pentraxin‑3 in acute coronary syndrome

Na Jiang, Shulong Zhou, Guanglei Wang, Ningning Jiang, Huaixin Wang, Feng Zhao
Article Number: 254
Published online on: 25 January 2021

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Article

HSP70 expression before and after treatment and its clinical value in patients with acute angle‑closure glaucoma

Hong Chen, Aijun Tian, Yixiang Wu, Rongrong Li, Ruijuan Han, Xiaowei Xu, Sumian Cheng
Article Number: 253
Published online on: 25 January 2021

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Article Open Access

4‑Methoxybenzylalcohol protects brain microvascular endothelial cells against oxygen‑glucose deprivation/reperfusion‑induced injury via activation of the PI3K/AKT signaling pathway

Qing Lin, Weili Wang, Liping Yang, Xiaohua Duan
Article Number: 252
Published online on: 24 January 2021

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Article Open Access

Preventive and therapeutic significance of octreotide combined with lansoprazole on post‑ERCP pancreatitis and its effect on serum amylase, inflammatory factors and immune function

Zhiliang Chen, Hong Fu, Jianfeng Fang, Jianhui Yang, Xin Zhu, Bingxiang Cheng, Tiannv Ding
Article Number: 251
Published online on: 22 January 2021

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Article Open Access

Correlations of cardiac function with inflammation, oxidative stress and anemia in patients with uremia

Heping Zhang, Lei Fan, Huawei Liao, Lirong Tu, Jie Zhang, Dan Xu, Jiangchao Feng
Article Number: 250
Published online on: 22 January 2021

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Article Open Access

High expression of PIG11 correlates with poor prognosis in gastric cancer

Juan Gu, Shu Zhang, Xin He, Sufang Chen, Yan Wang
Article Number: 249
Published online on: 22 January 2021

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Article Open Access

ER stress preconditioning ameliorates liver damage after hemorrhagic shock and reperfusion

David Peter Obert, Alexander Karl Wolpert, Nathan Lewis Grimm, Sebastian Korff
Article Number: 248
Published online on: 22 January 2021

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Article

Prognostic value of using glucosylceramide synthase and cytochrome P450 family 1 subfamily A1 expression levels for patients with triple‑negative breast cancer following neoadjuvant chemotherapy

Jiannan Liu, Shuhua Wang, Congcong Wang, Xiangshuo Kong, Ping Sun
Article Number: 247
Published online on: 22 January 2021

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Case Report

Successful treatment of Gaucher disease type 1 by enzyme replacement therapy over a 10-year duration in a Japanese pediatric patient: A case report

Yuji Oto, Takeshi Inoue, So Nagai, Shinichiro Tanaka, Hisashi Itabashi, Masahisa Shiraisihi, Akihisa Nitta, Nobuyuki Murakami, Hiroyuki Ida, Tomoyo Matsubara
Article Number: 246
Published online on: 22 January 2021

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Article Open Access

Improving motor function after chronic stroke by interactive gaming with a redesigned MR‑compatible hand training device

Loukas G. Astrakas, Gianluca De Novi, Mark P. Ottensmeyer, Christian Pusatere, Shasha Li, Michael A. Moskowitz, A. Aria Tzika
Article Number: 245
Published online on: 22 January 2021

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Review Open Access

COVID‑19 and its consequences on mental health (Review)

Konstantinos Tsamakis, Dimitrios Tsiptsios, Andreas Ouranidis, Christoph Mueller, Dimitrios Schizas, Christos Terniotis, Nikolaos Nikolakakis, Georgios Tyros, Stylianos Kympouropoulos, Andreas Lazaris, Demetrios A. Spandidos, Nikolaos Smyrnis, Emmanouil Rizos
Article Number: 244
Published online on: 22 January 2021

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Review Open Access

Ovarian endometriosis, a precursor of ovarian cancer: Histological aspects, gene expression and microRNA alterations (Review)

Adriana Ioana Gaia‑Oltean, Cornelia Braicu, Diana Gulei, Razvan Ciortea, Dan Mihu, Horace Roman, Alexandru Irimie, Ioana Berindan‑Neagoe
Article Number: 243
Published online on: 22 January 2021

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Article Open Access

Discovering pathways in benign prostate hyperplasia: A functional genomics pilot study

Zheling Chen, Minyao Ge
Article Number: 242
Published online on: 22 January 2021

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Article Open Access

Inhibition of heat shock protein 90 alleviates cholestatic liver injury by decreasing IL‑1β and IL‑18 expression

Chenhao Tong, Jiandong Li, Weiguo Lin, Wenda Cen, Weiguang Zhang, Zhiyang Zhu, Baochun Lu, Jianhua Yu
Article Number: 241
Published online on: 21 January 2021

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Review Open Access

Experimental models in peritoneal dialysis (Review)

Bo Yang, Mengmeng Wang, Xue Tong, Ghada Ankawi, Lin Sun, Hongtao Yang
Article Number: 240
Published online on: 21 January 2021

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Article Open Access

Circular RNA expression profile in human primary multiple intracranial aneurysm

Huimin Cao, Jia Chen, Xiaoyan Lai, Tianqin Liu, Ping Qiu, Shuanglin Que, Yanming Huang
Article Number: 239
Published online on: 21 January 2021

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Article Open Access

Sodium hydrosulfide alleviates dexamethasone‑induced cell senescence and dysfunction through targeting the miR‑22/sirt1 pathway in osteoblastic MC3T3‑E1 cells

Peng Li, Wei-Wei Mao, Shuai Zhang, Liang Zhang, Zhi-Rong Chen, Zhi-Dong Lu
Article Number: 238
Published online on: 21 January 2021

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Article Open Access

Risk factors for respiratory assistance in premature infants

Hai-Xin Li, Cai-Jie Gao, Shan Cheng, Zhi-Lei Mao, Huai-Yan Wang
Article Number: 237
Published online on: 21 January 2021

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Article Open Access

Decreased expression of serum semaphorin 3B is associated with poor prognosis of patients with hepatocellular carcinoma

Guang-Zhen Li, Di Shen, Guang-Hong Li, Meng Wei, Li-Jie Zheng, Zeng-Li Liu, Rong-Qi Sun, Shao-Jun Zhou, Zong-Li Zhang, Yan-Chao Gao
Article Number: 236
Published online on: 21 January 2021

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Article Open Access

MicroRNA‑598 inhibits the growth of triple negative breast cancer cells by targeting JAG1

Guohui Han, Xiangdong Bai, Hongchuan Jiang, Qiang He
Article Number: 235
Published online on: 21 January 2021

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Article Open Access

Long non‑coding RNA cyclin‑dependent kinase inhibitor 2B antisense ribonucleic acid 1 is associated with in‑stent restenosis and promotes human carotid artery smooth muscle cell proliferation and migration by sponging miR‑143‑3p

Huanhuan Ma, Aiqin Dong
Article Number: 234
Published online on: 21 January 2021

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Article Open Access

Pomelo peel oil alleviates cerebral NLRP3 inflammasome activation in a cardiopulmonary resuscitation rat model

Xin-Sen Zou, Lu Xie, Wen-Yan Wang, Gao-Yang Zhao, Xin-Yue Tian, Meng-Hua Chen
Article Number: 233
Published online on: 21 January 2021

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Article Open Access

Long non‑coding RNA MIAT promotes the proliferation and invasion of laryngeal squamous cell carcinoma cells by sponging microRNA‑613

Fucun Song, Yang Yang, Jixiang Liu
Article Number: 232
Published online on: 21 January 2021

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Review Open Access

Challenges of phototherapy for neonatal hyperbilirubinemia (Review)

Juan Wang, Genxin Guo, Aimin Li, Wen-Qi Cai, Xianwang Wang
Article Number: 231
Published online on: 20 January 2021

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Article Open Access

MicroRNA‑1323 serves as a biomarker in gestational diabetes mellitus and aggravates high glucose‑induced inhibition of trophoblast cell viability by suppressing TP53INP1

Lijun Liu, Jun Zhang, Yujuan Liu
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Published online on: 20 January 2021

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MicroRNA‑489‑3p plays a significant role in congenital hypothyroidism through regulating neuronal cell apoptosis via targeting translationally controlled tumor protein 1

Qin Liu, Yuehong Li, Yong Zhou
Article Number: 229
Published online on: 20 January 2021

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Published online on: 20 January 2021

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Recombinant interleukin-2 stimulates lymphocyte recovery in patients with severe COVID-19

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Article Number: 227
Published online on: 18 January 2021

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Novel applications of platelet concentrates in tissue regeneration (Review)

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Article Number: 226
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Quantitative T2 mapping of rats with chronic hepatitis

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Published online on: 18 January 2021

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Inhibition of the mevalonate pathway improves myocardial fibrosis

Huifeng Xu, Yi Shen, Chenyu Liang, Haifeng Wang, Junling Huang, Pengcheng Xue, Ming Luo
Article Number: 224
Published online on: 18 January 2021

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Emerging recognition of the complement system in hepatic ischemia/reperfusion injury, liver regeneration and recovery (Review)

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Published online on: 18 January 2021

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Effects of Streptococcus thermophilus on anterior cruciate ligament transection-induced early osteoarthritis in rats

Yen-You Lin, Nan-Fu Chen, San-Nan Yang, Yen-Hsuan Jean, Hsiao-Mei Kuo, Pei-Chin Chen, Chien-Wei Feng, Yu-Wei Liu, Yu-Cheng Lai, Zhi-Hong Wen
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Published online on: 18 January 2021

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Phenoxythiophene sulfonamide compound B355252 protects neuronal cells against glutamate‑induced excitotoxicity by attenuating mitochondrial fission and the nuclear translocation of AIF

Yuxin Zhang, Nailya S. Gliyazova, P. Andy Li, Gordon Ibeanu
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Published online on: 18 January 2021

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Schizandrin B attenuates hypoxia/reoxygenation injury in H9c2 cells by activating the AMPK/Nrf2 signaling pathway

Bo Zhao, Guang-Ping Li, Jian-Jun Peng, Li-Hui Ren, Li-Cheng Lei, Hui-Ming Ye, Zuo-Yan Wang, Sheng Zhao
Article Number: 220
Published online on: 18 January 2021

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LMTK2 regulates inflammation in lipopolysaccharide‑stimulated BV2 cells

Qianyun Rui, Shugang Cao, Xiaozhu Wang, Xiaoyu Duan, Xinyi  Iao, Wanli Dong, Qi Fang, Xueguang Zhang, Qun Xue
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Published online on: 18 January 2021

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miR‑155 promotes proliferation and epithelial‑mesenchymal transition of MCF‑7 cells

Xiaoyan Liu, Yongjun Li, Zhuo Li, Tian Hou
Article Number: 218
Published online on: 15 January 2021

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Efficacy and tolerability of sitagliptin and metformin compared with insulin as an initial therapy for newly diagnosed diabetic patients with severe hyperglycaemia

Mingqian He, Mei Deng, Jingya Wang, Pengxia Fan, Yue Wang, Xinrui Zhao, Yizhi He, Bingyin Shi, Jing Sui
Article Number: 217
Published online on: 15 January 2021

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Serum IL‑21 levels predict HBeAg decline during rescue therapy in patients with partial response to nucleos(t)ide analogues

Yue Li, Calvin Q. Pan, Shibo Ji, Gaiqin Yan, Jun Cheng, Shunai Liu, Huichun Xing
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Published online on: 15 January 2021

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Insulin-like growth factor-1 improves postoperative cognitive dysfunction following splenectomy in aged rats

Bin Wang, Xu Lin, Jiahui Zhou, Chunhui Xie, Chuan Li, Rui Dong, Gaofeng Zhang, Xiaopeng Sun, Mingshan Wang, Yanlin Bi
Article Number: 215
Published online on: 15 January 2021

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The vasodilatory mechanism of nitric oxide and hydrogen sulfide in the human mesenteric artery in patients with colorectal cancer

Awat Y. Hassan, Ismail M. Maulood, Abbas Salihi
Article Number: 214
Published online on: 15 January 2021

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A systematic review and meta‑analysis of minimally invasive vs. standard percutaneous nephrolithotomy in the surgical management of renal stones

Binbin Jiao, Zhenkai Luo, Tao Huang, Guan Zhang, Jiang Yu
Article Number: 213
Published online on: 15 January 2021

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miR‑142‑3p reduces the viability of human cervical cancer cells by negatively regulating the cytoplasmic localization of HMGB1

Hui Dong, Jie Song
Article Number: 212
Published online on: 14 January 2021

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Lidocaine attenuates CFA‑induced inflammatory pain in rats by regulating the MAPK/ERK/NF‑κB signaling pathway

Shuli Zhang, Yan Li, Yingjun Tu
Article Number: 211
Published online on: 14 January 2021

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Umbilical cord‑derived mesenchymal stem cells exert anti‑fibrotic action on hypertrophic scar‑derived fibroblasts in co‑culture by inhibiting the activation of the TGF β1/Smad3 pathway

Xianglong Meng, Xinxin Gao, Xinxin Chen, Jiaao Yu
Article Number: 210
Published online on: 14 January 2021

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T‑regulatory cells from patients with rheumatoid arthritis retain suppressor functions in vitro

Daniil Shevyrev, Valeriy Tereshchenko, Vladimir Kozlov, Alexey Sizikov, Oksana Chumasova, Veroniсa Koksharova
Article Number: 209
Published online on: 14 January 2021

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NOD‑like receptor X1, tumor necrosis factor receptor‑associated factor 6 and NF‑κB are associated with clinicopathological characteristics in gastric cancer

Zhe Fan, Jiyong Pan, Hai Wang, Yewei Zhang
Article Number: 208
Published online on: 14 January 2021

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Dexpanthenol reduces fibrosis and aids repair following nerve laceration and neurorrhaphy

Gokhan Karahan, Huseyin Kaya, Recep Selçuk Eyceyurt, Mumin Alper Erdogan, Gurkan Yigitturk, Oytun Erbas
Article Number: 207
Published online on: 13 January 2021

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Effects of 10 Hz repetitive transcranial magnetic stimulation of the right dorsolateral prefrontal cortex in the vegetative state

Xin Ge, Yue Zhang, Tian Xin, Xue Luan
Article Number: 206
Published online on: 13 January 2021

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Detection of microRNA‑33a‑5p in serum, urine and renal tissue of patients with IgA nephropathy

Lihua Liu, Aosong Duan, Qiaoyan Guo, Guangdong Sun, Wenpeng Cui, Xuehong Lu, Hongyu Yu, Ping Luo
Article Number: 205
Published online on: 11 January 2021

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HSP60 participates in the anti‑glioma effects of curcumin

Fengchen Bi, Junyan Wang, Xiaomin Zheng, Jingjing Xiao, Chai Zhi, Jinhai Gu, Yumei Zhang, Juan Li, Zhenhua Miao, Yin Wang, Yunhong Li
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Published online on: 11 January 2021

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Apoptosis inhibition is involved in improvement of sevoflurane‑induced cognitive impairment following normobaric hyperoxia preconditioning in aged rats

Ying Wang, Chun-Ping Yin, Yan-Lei Tai, Zi-Jun Zhao, Zhi-Yong Hou, Qiu-Jun Wang
Article Number: 203
Published online on: 11 January 2021

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Curcumin suppresses the proliferation of oral squamous cell carcinoma through a specificity protein 1/nuclear factor‑κB‑dependent pathway

Tian Liu, Tian Long, Haosen Li
Article Number: 202
Published online on: 11 January 2021

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Mycoplasma pneumoniae pneumonia with pulmonary embolism: A study on pediatric cases in Jilin province of China

Chu-Qiao Sheng, Chun-Feng Yang, Yu Ao, Zhi-Yue Zhao, Yu-Mei Li
Article Number: 201
Published online on: 11 January 2021

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Xue Wang, Xuren Sun, Ran Ao, Zilu Zeng, Dan Li, Yiling Li
Article Number: 200
Published online on: 11 January 2021

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miR‑361‑5p regulates ovarian cancer cell proliferation and apoptosis by targeting TRAF3

Jianmei Ling, Panwen He
Article Number: 199
Published online on: 11 January 2021

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Efficacy of bupivacaine infiltration for controlling post‑tonsillectomy pain, duration of surgery and post‑operative morbidities: A systematic review and meta‑analysis

Juan Wang, Ning Wang, Fanghua Gong
Article Number: 198
Published online on: 08 January 2021

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Shuxuetong injection simultaneously ameliorates dexamethasone‑driven vascular calcification and osteoporosis

Zhe Xu, Xiaoguang Liu, Yanqing Li, Hongliang Gao, Tao He, Chunlei Zhang, Wei Hao, Xu Teng
Article Number: 197
Published online on: 08 January 2021

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Influence of esophageal morphology on the clinical efficacy of peroral endoscopic myotomy in treating advanced achalasia cardia

Dan Liu, Yue-Yuan Liu, Jia-Xin Chen, Lei Song, Yang-Yang Zhou, Saif Ullah, Li-Xia Zhao, Bin Hai, Qing-Fen Zheng, Dong-Ying Li, De-Zhi He, Bing-Rong Liu
Article Number: 196
Published online on: 08 January 2021

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Synergistic inhibitory effects of low‑dose decitabine in combination with bortezomib in the AML cell line Kasumi‑1

Vassiliki Mpakou, Aris Spathis, Anthi Bouhla, Efthimia Mpazani, Sotirios Papageorgiou, Konstantinos Gkontopoulos, Eirini Glezou, Thomas Thomopoulos, Periklis Foukas, Vasiliki Pappa
Article Number: 195
Published online on: 08 January 2021

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Ergosterol limits osteoarthritis development and progression through activation of Nrf2 signaling

Dawei Cai, Huyong Yan, Jun Liu, Sichun Chen, Longhai Jiang, Xiaoxu Wang, Jian Qin
Article Number: 194
Published online on: 08 January 2021

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Somatically acquired mutations in primary myelofibrosis: A case report and meta‑analysis

Yongming Xia, Qingxiao Hong, Zhibin Gao, Shijun Wang, Shiwei Duan
Article Number: 193
Published online on: 07 January 2021

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MicroRNA‑615‑5p regulates the proliferation and apoptosis of breast cancer cells by targeting HSF1

Kaisheng Liu, Rong Ma
Article Number: 192
Published online on: 07 January 2021

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Validation of a novel UPLC‑HRMS method for human whole‑blood cyclosporine and comparison with a CMIA immunoassay

Xiaoxue Wang, Wei Qin, Wenqian Chen, Huifang Liu, Dan Zhang, Xianglin Zhang, Pengmei Li
Article Number: 191
Published online on: 07 January 2021

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Mechanism of circadian regulation of the NRF2/ARE pathway in renal ischemia‑reperfusion

Qian Sun, Cheng Zeng, Li Du, Chong Dong
Article Number: 190
Published online on: 07 January 2021

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Role of ultrasound and CT in the early diagnosis and surgical treatment of primary sternal osteomyelitis caused by Salmonella: Case reports

Mengjiao Qian, Jing Wang, Jun Li, Sibo Wang, Zhongyin Wang, Xiao Chen, Haibo Ou, Yuanzhong Liang, Xuguan Peng
Article Number: 189
Published online on: 07 January 2021

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Lactobacillus spp. reduces ethanol‑induced liver oxidative stress and inflammation in a mouse model of alcoholic steatohepatitis

Pei-Shan Hsieh, Ching-Wei Chen, Yi-Wei Kuo, Hsieh-Hsun Ho
Article Number: 188
Published online on: 07 January 2021

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Abnormal expression of TRIAP1 and its role in gestational diabetes mellitus‑related pancreatic β cells

Linxia Li, Kaihan Yang, Fang Ye, Yi Xu, Lili Cao, Jia Sheng
Article Number: 187
Published online on: 07 January 2021

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Sulforaphane protects human umbilical vein endothelial cells from oxidative stress via the miR‑34a/SIRT1 axis by upregulating nuclear factor erythroid‑2‑related factor 2

Tao Li, Qi Pang, Yongbin Liu, Ming Bai, Yu Peng, Zheng Zhang
Article Number: 186
Published online on: 07 January 2021

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Combination of the neutrophil to lymphocyte ratio and serum toluidine red unheated serum test titer as a predictor of neurosyphilis in HIV‑negative patients

Caifeng He, Xianjin Shang, Wenbei Liu, Shouyun Hang, Jingtao Chen, Chao Ci
Article Number: 185
Published online on: 07 January 2021

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Effects of transcutaneous electrical acupoint stimulation on perioperative immune function and postoperative analgesia in patients undergoing radical mastectomy: A randomized controlled trial

Li Ao, Jinlin Shi, Yaowu Bai, Shan Zhang, Jianhui Gan
Article Number: 184
Published online on: 07 January 2021

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Experimental pretreatment with YES‑10®, a plant extract rich in scutellarin and chlorogenic acid, protects hippocampal neurons from ischemia/reperfusion injury via antioxidant role

Young Eun Park, Yoohun Noh, Dae Won Kim, Tae-Kyeong Lee, Ji Hyeon Ahn, Bora Kim, Jae-Chul Lee, Cheol Woo Park, Joon Ha Park, Jong Dai Kim, Young-Myeong Kim, Il Jun Kang, Ji-Won Lee, Sung-Su Kim, Moo-Ho Won
Article Number: 183
Published online on: 07 January 2021

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Application of a prediction model with laboratory indexes in the risk stratification of patients with COVID‑19

Jiru Ye, Xiaoqing Zhang, Feng Zhu, Yao Tang
Article Number: 182
Published online on: 05 January 2021

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FABP4 alleviates endoplasmic reticulum stress‑mediated ischemia‑reperfusion injury in PC12 cells via regulation of PPARγ

Xiao-Lan Yang, Jian-Hua Mi, Qing Dong
Article Number: 181
Published online on: 05 January 2021

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IOX1 protects from TGF‑β induced fibrosis in LX‑2 cells via the regulation of extracellular matrix protein expression

Tian Tian, Rujia Xie, Kaize Ding, Bing Han, Qin Yang, Xue Yang
Article Number: 180
Published online on: 05 January 2021

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miR‑206 serves an important role in polycystic ovary syndrome through modulating ovarian granulosa cell proliferation and apoptosis

Jie Zhou, Xuejing Jin, Zhumei Sheng, Zhifen Zhang
Article Number: 179
Published online on: 05 January 2021

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Changes and significance of hydrodynamic parameters in Budd‑Chiari syndrome with obstruction of the inferior vena cava prior to and after interventional therapy

Lulu Lyu, Peng Xu, Jie Ping, Chunfeng Hu, Kai Xu
Article Number: 178
Published online on: 05 January 2021

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January-2026 Volume 31 Issue 1

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Adiposity indices and bone health amongst Malaysian adults: Evidence from a cross‑sectional study

Wenjian Zhao, Weizheng Zhang, Kok-Yong Chin, Xiaodong Ma, Hashwin Singh Tejpal Singh, Sophia Ogechi Ekeuku, Yuanzhong Wang, Xia Ji, Yang Guo, Sok Kuan Wong, Norliza Muhammad, Teh Rohaila Jamil, Saharuddin Ahmad
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Published online on: 21 November 2025

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Ginsenoside Re attenuates homocysteine‑induced endothelial cell ferroptosis through upregulation of GPX4/xCT signaling

Shaolin Li, Chenge Zhao, Shengqin Yu, Kaijing Yang, Shuying Zhang, Sixu Liu
Article Number: 27
Published online on: 21 November 2025

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Intussusception of the initial jejunum secondary to adenoma in the third and fourth portions of the duodenum: A case report

Lingbo Huo, Lixing Ma
Article Number: 26
Published online on: 21 November 2025

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[Corrigendum] Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/β‑catenin signaling pathway

Yun Yi, Bing Liao, Ziwen Zheng, Xiaorong Yang, Yunsheng Yang, Yanfang Zhou, Buzhen Tan, Xinfeng Yang
Article Number: 25
Published online on: 19 November 2025

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Identification of early diagnostic biomarkers in venous thromboembolism: A bioinformatic analysis based on crosstalk between pyroptosis and venous thromboembolism

Shengbin Han, Jingzhe Xu, Chenchen Yu, Hongxi Guan, Shun Ding
Article Number: 24
Published online on: 18 November 2025

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[Retracted] Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 23
Published online on: 17 November 2025

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Atorvastatin ameliorates chronic subdural hematomas by interrupting the ‘chronic subdural hematoma cycle’ via inhibition of the inflammatory response

Jinqi Yan, Xiaohu Wang, Chen Liang
Article Number: 22
Published online on: 14 November 2025

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Diagnosis and treatment of invasive fungal disease in children with hematological malignancies after chemotherapy: Challenges and strategies (Review)

Mingxin He, Feng Chen, Xiaomin Xian, Zhi Guo
Article Number: 21
Published online on: 14 November 2025

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Venetoclax combined with azacitidine for treatment of a blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

Yunching Lai, Xiaolei Chen, Hebing Zhou
Article Number: 20
Published online on: 10 November 2025

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Diagnostic challenge of aneurysmal dermatofibroma mimicking cutaneous metastasis in a patient with lung cancer: A case report

Jong Yun Choi, Heeyang Park, Jangyoun Choi
Article Number: 19
Published online on: 10 November 2025

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[Retracted] miRNA‑30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene

Shan Muhammad, Qingchao Tang, Liu Wei, Qian Zhang, Guiyu Wang, Bilal Umar Muhammad, Kavanjit Kaur, Tatiana Kamchedalova, Zhao Gang, Zheng Jiang, Zheng Liu, Xishan Wang
Article Number: 18
Published online on: 10 November 2025

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Leucine supplementation modulates lipid metabolism and metabolic pathways in mice with type 1 diabetes: A metabolomics study

Jeng-Yuan Yao, De-Tian-Yu Tzeng, Cai-Hong Feng, Gong-Man Xiao, Tian-Ni You, Ru-Yu Zheng
Article Number: 17
Published online on: 06 November 2025

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Chronic maxillary sinusitis masquerading as a maxillary sinus neoplasm: A case report

Ji-Hyeon Oh, Seong-Gon Kim, Su-Young Kim
Article Number: 16
Published online on: 04 November 2025

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[Retracted] MicroRNA‑490‑3p regulates cell proliferation and apoptosis in gastric cancer via direct targeting of AKT1

Hong Yu, Jianying Sun, Shaochang Jiang, Ying Xu
Article Number: 15
Published online on: 04 November 2025

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A comparison of bridging external fixation vs. combined external fixation for preventing radial height loss in older patients with distal radius fractures

Jingqiao Li, Yipeng Yang, Xu Zhang, Dandan Zhang, Yadong Yu, Rong Chen, Wei Du
Article Number: 14
Published online on: 30 October 2025

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Primary epithelioid angiomatous nodule of the vocal cord: A case report and literature review

Keda Li, Bin Huang, Lubing Cai, Mingqi Huang, Jianping Shi, Mingdi Jin, Ning Qian, Yongkang Guo
Article Number: 13
Published online on: 29 October 2025

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Hepatic perivascular epithelioid cell tumor: A rare mesenchymal tumor with epithelioid features: A case report

Mahmoud Abbas, Benjamin Strücker, Mehmet Haluk Morgül, Andreas Pascher, Wolfgang Hartmann, Eva Wardelmann
Article Number: 12
Published online on: 29 October 2025

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[Corrigendum] Changes in the interstitial cells of Cajal in the gallbladder of guinea pigs fed a lithogenic diet

Lei Huang, Chao Ding, Xinmin Si
Article Number: 11
Published online on: 29 October 2025

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Article

Evaluation of total oxidant status/total antioxidant capacity and DNA damage in neonates with high lactate levels in umbilical cord blood gases

Burcu Cebeci, Aydemir Yalvaç, Derya Büyükkayhan, Dilek Kurnaz, Hakan Çakir, Murat Elevli
Article Number: 10
Published online on: 29 October 2025

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Treatment of a mandibular molar with primary failure of eruption: A case report

Ming Guo, Weisheng Zhang
Article Number: 9
Published online on: 29 October 2025

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Effect of the water‑soluble matrix of nanometer pearl powder on the osteogenic differentiation of hFOB1.19 cells

Xinghuanyu Xu, Lin Liu, Wenbai Zhang, Pu Xu
Article Number: 8
Published online on: 29 October 2025

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[Retracted] Long non‑coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3‑kinase/protein kinase B signaling pathway

Bin Yan, Aikepaer Wubuli, Yidong Liu, Xin Wang
Article Number: 7
Published online on: 27 October 2025

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Diagnostic significance of the checkpoint kinase 1 gene in high‑grade gastroenteropancreatic neuroendocrine neoplasms

Na Li, Jianduo An, Yanping Hu
Article Number: 6
Published online on: 24 October 2025

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[Retracted] Establishment of ApoE‑knockout mouse model of preeclampsia and relevant mechanisms

Wenjuan Sun, Baoxia Cui, Fanzhen Hong, Yongping Xu
Article Number: 5
Published online on: 23 October 2025

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Investigating the association between uterine fibroids and weight‑bearing joint osteoarthritis based on a bidirectional Mendelian randomization study

Xiao Ma, Jingjing Ma, Han Zhang, Xiaodong Jia, Tianrui Wang, Shanshan Ma, Yingze Zhang
Article Number: 4
Published online on: 21 October 2025

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Epimedin C: A promising neuroprotective agent that can participate in mediating the JNK/Nrf2/HO‑1 signaling pathway to prevent neurodegenerative diseases

Chao Cong, Xuan-Ling Li, Guang-Yao Lin, Lian-Wei Xu
Article Number: 3
Published online on: 21 October 2025

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Application of pleural effusion cell blocks for immunohistochemistry and EGFR gene mutation testing for advanced lung cancer

Shouxiang Zhao, Yuhong Liu, Tao Wang, Ying Li, Ze Chen, Xiaoshan Cai
Article Number: 2
Published online on: 21 October 2025

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[Corrigendum] Evaluation of the inhibitory effects of vaginal microorganisms on sperm motility in vitro

Huan Wang, Tingtao Chen, Yidan Chen, Tao Luo, Buzhen Tan, Houyang Chen, Hongbo Xin
Article Number: 1
Published online on: 16 October 2025

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February-2026 Volume 31 Issue 2

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Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

Chenao Wang, Yufeng Liu, Yaqing Liu, Baicheng Li, Xingdong Hou, Bowei Lu, Zhao Chen, Shili Ning
Article Number: 48
Published online on: 05 December 2025

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Calcifying fibrous tumours of the diaphragm: A case report and literature review

Sijia Guo, Wenya Han, Lingling Yuan, Hansheng Wang, Ge Cheng, Yaxin Tuo, Chuanyong Xiao, Jialong Guo, Meifang Wang
Article Number: 47
Published online on: 05 December 2025

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Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model

Omer Cennet, Akbar Hajiyev, Burcin Şener, Filiz Akbiyik, Cenk Sökmensüer, Osman Abbasoglu
Article Number: 40
Published online on: 01 December 2025

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The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

Xuemei Sun, Min Yang, Lingling Wan, Hua Zhong
Article Number: 39
Published online on: 01 December 2025

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[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 38
Published online on: 01 December 2025

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Effects of small incision lenticule extraction and femtosecond laser‑assisted in situ keratomileusis on choroidal thickness and blood flow density in patients with myopia

Shirui Yang, Tiantian Qian, Min Tang, Jing Zhang, Jie Hou, Yahui Dong, Yulin Lei
Article Number: 37
Published online on: 01 December 2025

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Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

Yanru Guo, Zhi Li, Yiqun Zhang, Zhijuan Pan, Jiajia Sun, Ying Zhang, Shuting Chang, Zhiping Guo
Article Number: 36
Published online on: 01 December 2025

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Patients with sickle cell disease and asthma have a higher risk for acute chest syndrome: A systematic review and meta‑analysis of observational studies

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 35
Published online on: 28 November 2025

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Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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