Risk factors for respiratory assistance in premature infants
- Hai-Xin Li
- Cai-Jie Gao
- Shan Cheng
- Zhi-Lei Mao
- Huai-Yan Wang
Affiliations: Department of Child Healthcare, Changzhou Women and Children Health Care Hospital, Changzhou, Jiangsu 213000, P.R. China, Department of Infectious Disease, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China
- Published online on: January 21, 2021 https://doi.org/10.3892/etm.2021.9668
Copyright: © Li
et al. This is an open access article distributed under the
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Commons Attribution License.
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Premature infants are prone to dyspnea after birth due to immature development, and some infants require respiratory assistance. However, the risk factors for respiratory assistance in premature infants are rarely reported. The present study enrolled 3,394 premature infants (665 infants had been provided with respiratory assistance and 2,729 had not used respiratory assistance) to retrospectively analyze the risk factors associated with respiratory aid. The multivariate logistic regression analysis demonstrated that placental abnormality [odds ratio (OR)=1.284; P=0.048], the male sex (OR=0.696; P=0.001), delivery via cesarean section (OR=1.538; P<0.001), low 1‑min Apgar score (OR=0.727; P<0.001), low birth weight (OR=0.999; P=0.005) and low gestational age (OR=0.616; P<0.001) were independent risk factors for respiratory assistance in premature infants. Overall, a number of risk factors, including placental abnormality, cesarean section, low 1‑min Apgar score, low birth weight and small gestational age, were identified for respiratory assistance in premature infants. By conducting a risk assessment of risk factors at birth and using this information to provide timely respiratory assistance, the survival rates of premature infants may increase.