|
1
|
Ghosh D and Dawson MR: Microenvironment
Influences cancer cell mechanics from tumor growth to metastasis.
Adv Exp Med Biol. 1092:69–90. 2018.PubMed/NCBI View Article : Google Scholar
|
|
2
|
da Cunha BR, Domingos C, Stefanini ACB,
Henrique T, Polachini GM, Castelo-Branco P and Tajara EH: Cellular
interactions in the tumor microenvironment: The role of secretome.
J Cancer. 10:4574–4587. 2019.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Barbazan J and Matic Vignjevic D: Cancer
associated fibroblasts: Is the force the path to the dark side?
Curr Opin Cell Biol. 56:71–79. 2019.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Prenen H and Mazzone M: Tumor-associated
macrophages: A short compendium. Cell Mol Life Sci. 76:1447–1458.
2019.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Anfossi S, Fu X, Nagvekar R and Calin GA:
MicroRNAs, regulatory messengers inside and outside cancer cells.
Adv Exp Med Biol. 1056:87–108. 2018.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Allavena P and Mantovani A: Immunology in
the clinic review series; focus on cancer: Tumour-associated
macrophages: Undisputed stars of the inflammatory tumour
microenvironment. J Clin Exp Immunol. 167:195–205. 2012.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Shapouri-Moghaddam A, Mohammadian S,
Vazini H, Taghadosi M, Esmaeili SA, Mardani F, Seifi B, Mohammadi
A, Afshari JT and Sahebkar A: Macrophage plasticity, polarization,
and function in health and disease. J Cell Physiol. 233:6425–6440.
2018.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Orecchioni M, Ghosheh Y, Pramod AB and Ley
K: Macrophage Polarization: Different gene signatures in M1(LPS+)
vs. Classically and M2(LPS-) vs. Alternatively activated
macrophages. Front Immunol. 10(1084)2019.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Tamura R, Tanaka T, Yamamoto Y, Akasaki Y
and Sasaki H: Dual role of macrophage in tumor immunity.
Immunotherapy. 10:899–909. 2018.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Laviron M and Boissonnas A: Ontogeny of
tumor-associated macrophages. Front Immunol.
10(1799)2019.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Poh AR and Ernst M: Targeting macrophages
in cancer: From bench to bedside. Front Oncol 8, 49, 2018.
|
|
12
|
Salmaninejad A, Valilou SF, Soltani A,
Ahmadi S, Abarghan YJ, Rosengren RJ and Sahebkar A:
Tumor-associated macrophages: Role in cancer development and
therapeutic implications. Cell Oncol (Dordr). 42:591–608.
2019.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Martinez FO and Gordon S: The M1 and M2
paradigm of macrophage activation: Time for reassessment.
F1000Prime Rep. 6:6–13. 2014.PubMed/NCBI View
Article : Google Scholar
|
|
14
|
Mantovani A, Sica A, Sozzani S, Allavena
P, Vecchi A and Locati M: The chemokine system in diverse forms of
macrophage activation and polarization. Trends Immunol. 25:677–686.
2004.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Yang L and Zhang Y: Tumor-associated
macrophages: From basic research to clinical application. J Hematol
Oncol. 10(58)2017.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Chen Y and Zhang X: Pivotal regulators of
tissue homeostasis and cancer: Macrophages. Exp Hematol Oncol.
6(23)2017.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Soldano S, Pizzorni C, Paolino S,
Trombetta AC, Montagna P, Brizzolara R, Ruaro B, Sulli A and Cutolo
M: Alternatively Activated (M2) macrophage phenotype is inducible
by endothelin-1 in cultured human macrophages. PLoS One.
11(e0166433)2016.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Chavez-Galan L, Olleros ML, Vesin D and
Garcia I: Much More than M1 and M2 Macrophages, There are also
CD169(+) and TCR(+) Macrophages. Frontiers Immunol.
6(263)2015.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Roszer T: Understanding the mysterious M2
macrophage through activation markers and effector mechanisms.
Mediators Inflamm. 2015(816460)2015.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Ruytinx P, Proost P, Van Damme J and
Struyf S: Chemokine-Induced Macrophage Polarization in Inflammatory
Conditions. Front Immunol. 9(1930)2018.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Szebeni GJ, Vizler C, Kitajka K and Puskas
LG: Inflammation and Cancer: Extra- and intracellular determinants
of tumor-associated macrophages as tumor promoters. Mediators
Inflamm. 2017(9294018)2017.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Edin S, Wikberg ML, Rutegard J, Oldenborg
PA and Palmqvist R: Phenotypic skewing of macrophages in vitro by
secreted factors from colorectal cancer cells. PLoS One.
8(e74982)2013.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Kamoshida G, Matsuda A, Sekine W, Mizuno
H, Oku T, Itoh S, Irimura T and Tsuji T: Monocyte differentiation
induced by co-culture with tumor cells involves RGD-dependent cell
adhesion to extracellular matrix. Cancer Lett. 315:145–152.
2012.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Neyen C, Pluddemann A, Mukhopadhyay S,
Maniati E, Bossard M, Gordon S and Hagemann T: Macrophage scavenger
receptor a promotes tumor progression in murine models of ovarian
and pancreatic cancer. J Immunol. 190:3798–3805. 2013.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Wang X, Zhao X, Wang K, Wu L and Duan T:
Interaction of monocytes/macrophages with ovarian cancer cells
promotes angiogenesis in vitro. Cancer Sci. 104:516–523.
2013.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Hoarau-Vechot J, Rafii A, Touboul C and
Pasquier J: Halfway between 2D and animal models: Are 3D cultures
the ideal tool to study cancer-microenvironment interactions? Int J
Mol Sci. 19(181)2018.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Xu X, Farach-Carson MC and Jia X:
Three-dimensional in vitro tumor models for cancer research and
drug evaluation. Biotechnol Adv. 32:1256–1268. 2014.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Lv D, Hu Z, Lu L, Lu H and Xu X:
Three-dimensional cell culture: A powerful tool in tumor research
and drug discovery. Oncol Lett. 14:6999–7010. 2017.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Holle AW, Young JL and Spatz JP: In vitro
cancer cell-ECM interactions inform in vivo cancer treatment. Adv
Drug Deliv Rev. 97:270–279. 2016.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Rebelo SP, Pinto C, Martins TR, Harrer N,
Estrada MF, Loza-Alvarez P, Cabecadas J, Alves PM, Gualda EJ,
Sommergruber W and Brito C: 3D-3-culture: A tool to unveil
macrophage plasticity in the tumour microenvironment. Biomaterials.
163:185–197. 2018.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Grolman JM, Zhang D, Smith AM, Moore JS
and Kilian KA: Rapid 3D extrusion of synthetic tumor
microenvironments. Adv Mater. 27:5512–5517. 2015.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Tevis KM, Cecchi RJ, Colson YL and
Grinstaff MW: Mimicking the tumor microenvironment to regulate
macrophage phenotype and assessing chemotherapeutic efficacy in
embedded cancer cell/macrophage spheroid models. Acta Biomater.
50:271–279. 2017.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Dondajewska E, Juzwa W, Mackiewicz A and
Dams-Kozlowska H: Heterotypic breast cancer model based on a silk
fibroin scaffold to study the tumor microenvironment. Oncotarget.
9:4935–4950. 2018.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Penderecka K, Ibbs M, Kaluzna A,
Lewandowska A, Marszalek A, Mackiewicz A and Dams-Kozlowska H:
Implementation of a dynamic culture condition to the heterotypic 3D
breast cancer model. J Biomed Mater Res B Appl Biomater.
108:1186–1197. 2020.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Scholzen T and Gerdes J: The Ki-67
protein: From the known and the unknown. J Cell Physiol.
182:311–322. 2000.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Asghar W, El Assal R, Shafiee H, Pitteri
S, Paulmurugan R and Demirci U: Engineering cancer
microenvironments for in vitro 3-D tumor models. Mater Today
(Kidlington). 18:539–553. 2015.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Devarasetty M, Mazzocchi AR and Skardal A:
Applications of bioengineered 3D tissue and tumor organoids in drug
development and precision medicine: Current and future. BioDrugs.
32:53–68. 2018.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Vidmar J, Chingwaru C and Chingwaru W:
Mammalian cell models to advance our understanding of wound
healing: A review. J Sur Res. 210:269–280. 2017.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Xu R and Richards FM: Development of in
vitro co-culture model in anti-cancer drug development cascade.
Comb Chem High Throughput Screen. 20:451–457. 2017.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Gordon JL, Brown MA and Reynolds MM:
Cell-Based methods for determination of efficacy for candidate
therapeutics in the clinical management of cancer. Diseases.
6(85)2018.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Egeblad M, Nakasone ES and Werb Z: Tumors
as organs: Complex tissues that interface with the entire organism.
Dev Cell. 18:884–901. 2010.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Sanchez LR, Borriello L, Entenberg D,
Condeelis JS, Oktay MH and Karagiannis GS: The emerging roles of
macrophages in cancer metastasis and response to chemotherapy. J
Leukoc Biol. 106:259–274. 2019.PubMed/NCBI View Article : Google Scholar
|
|
44
|
de la Cruz-Merino L, Barco-Sanchez A,
Henao Carrasco F, Nogales Fernandez E, Vallejo Benitez A, Brugal
Molina J, Martinez Peinado A, Grueso Lopez A, Ruiz Borrego M, Codes
Manuel de Villena M, et al: New insights into the role of the
immune microenvironment in breast carcinoma. Clin Dev Immunol.
2013(785317)2013.PubMed/NCBI View Article : Google Scholar
|
|
45
|
Galdiero MR, Bonavita E, Barajon I,
Garlanda C, Mantovani A and Jaillon S: Tumor associated macrophages
and neutrophils in cancer. Immunobiology. 218:1402–1410.
2013.PubMed/NCBI View Article : Google Scholar
|
|
46
|
Shahbazi MA, Sedighi M, Bauleth-Ramos T,
Kant K, Correia A, Poursina N, Sarmento B, Hirvonen J and Santos
HA: Targeted reinforcement of macrophage reprogramming toward M2
polarization by IL-4-loaded hyaluronic acid particles. ACS Omega.
3:18444–18455. 2018.PubMed/NCBI View Article : Google Scholar
|
|
47
|
Masjedi A, Hashemi V, Hojjat-Farsangi M,
Ghalamfarsa G, Azizi G, Yousefi M and Jadidi-Niaragh F: The
significant role of interleukin-6 and its signaling pathway in the
immunopathogenesis and treatment of breast cancer. Biomed
Pharmacother. 108:1415–1424. 2018.PubMed/NCBI View Article : Google Scholar
|
|
48
|
Chen C, Zhao S, Karnad A and Freeman JW:
The biology and role of CD44 in cancer progression: Therapeutic
implications. J Hematol Oncol. 11(64)2018.PubMed/NCBI View Article : Google Scholar
|
|
49
|
Gee K, Lim W, Ma W, Nandan D, Diaz-Mitoma
F, Kozlowski M and Kumar A: Differential regulation of CD44
expression by lipopolysaccharide (LPS) and TNF-alpha in human
monocytic cells: Distinct involvement of c-Jun N-terminal kinase in
LPS-induced CD44 expression. J Immunol. 169:5660–5672.
2002.PubMed/NCBI View Article : Google Scholar
|
|
50
|
Xu H, Manivannan A, Crane I, Dawson R and
Liversidge J: Critical but divergent roles for CD62L and CD44 in
directing blood monocyte trafficking in vivo during inflammation.
Blood. 112:1166–1174. 2008.PubMed/NCBI View Article : Google Scholar
|
|
51
|
Takahashi H, Sakakura K, Kudo T, Toyoda M,
Kaira K, Oyama T and Chikamatsu K: Cancer-associated fibroblasts
promote an immunosuppressive microenvironment through the induction
and accumulation of protumoral macrophages. Oncotarget.
8:8633–8647. 2017.PubMed/NCBI View Article : Google Scholar
|
|
52
|
Zhang A, Qian Y, Ye Z, Chen H, Xie H, Zhou
L, Shen Y and Zheng S: Cancer-associated fibroblasts promote M2
polarization of macrophages in pancreatic ductal adenocarcinoma.
Cancer Med. 6:463–470. 2017.PubMed/NCBI View Article : Google Scholar
|
|
53
|
Murray PJ, Allen JE, Biswas SK, Fisher EA,
Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence
T, et al: Macrophage activation and polarization: Nomenclature and
experimental guidelines. Immunity. 41:14–20. 2014.PubMed/NCBI View Article : Google Scholar
|
