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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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May-2021 Volume 21 Issue 5

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Review Open Access

Understanding the genetics and neurobiological pathways behind addiction (Review)

Alexandra Popescu, Maria Marian, Ana Miruna Drăgoi, Radu-Virgil Costea
Article Number: 544
Published online on: 23 March 2021

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Article

Abdominal paraaortic paraganglioma: Management of intraoperative hemodynamic emergencies during elective resection procedures (A case presentation)

Ovidiu Stiru, Anca Dragan, Cristina Adamache, Petru Razvan Dragulescu, Carmen Stiru, Adrian Tulin, Nicolae Bacalbasa, Irina Balescu, Camelia Diaconu, Roxana Carmen Geana, Cornel Savu, Vlad Anton Iliescu
Article Number: 543
Published online on: 23 March 2021

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Article

Assessing the values of circulating immune complexes in multiple sclerosis patients following immunomodulator or corticosteroid treatment

Any Docu Axelerad, Alina Zorina Stroe, Anca Elena Gogu, Daniel Docu Axelerad
Article Number: 542
Published online on: 23 March 2021

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Article

Orthopedic surgery approach with uncemented metallic prosthesis in knee osteoarthritis increases the quality of life of young patients

Bogdan Uivaraseanu, Simona Bungau, Delia Mirela Tit, Tapan Behl, Teodor Andrei Maghiar, Octavian Maghiar, Carmen Pantis, Dana Carmen Zaha, Jenel M. Patrascu
Article Number: 541
Published online on: 23 March 2021

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Review Open Access

PI3K/AKT/mTOR signalling pathway involvement in renal cell carcinoma pathogenesis (Review)

Daniela Miricescu, Daniela Gabriela Balan, Adrian Tulin, Ovidiu Stiru, Ileana Adela Vacaroiu, Doina Andrada Mihai, Cristian Constantin Popa, Raluca Ioana Papacocea, Mihaly Enyedi, Nedelea Andrei Sorin, Guenadiy Vatachki, Dragoș Eugen Georgescu, Adriana Elena Nica, Constantin Stefani
Article Number: 540
Published online on: 23 March 2021

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Review Open Access

Impact of adipose tissue in chronic kidney disease development (Review)

Daniela Miricescu, Daniela Gabriela Balan, Adrian Tulin, Ovidiu Stiru, Ileana Adela Vacaroiu, Doina Andrada Mihai, Cristian Constantin Popa, Mihaly Enyedi, Andrei Sorin Nedelea, Adriana Elena Nica, Constantin Stefani
Article Number: 539
Published online on: 23 March 2021

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Article

Discrepancy in results between dipstick urinalysis and urine sediment microscopy

Anca Bacârea, Gyula László Fekete, Bianca Liana Grigorescu, Vladimir Constantin Bacârea
Article Number: 538
Published online on: 23 March 2021

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Article

Practical safety in the diagnosis and treatment of congenital isolated tracheoesophageal fistula

Radu-Iulian Spataru, Dan-Alexandru Iozsa, Mircea Ovidiu Denis Lupusoru, Dragos Serban, Catalin Cirstoveanu
Article Number: 537
Published online on: 23 March 2021

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Case Report Open Access

Unexpected diagnosis for a gastric polyp: Granular cell tumor: Case report and review of the literature

Sorina Maria Taban, Robert Alexandru Barna, Alis Liliana Carmen Dema, Iulia Maria Ratiu, Oana Popa, Andrei Dorel Plopeanu
Article Number: 536
Published online on: 23 March 2021

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Review Open Access

Nanomedicine to modulate immunotherapy in cutaneous melanoma (Review)

Simona Ruxandra Volovat, Serban Negru, Cati Raluca Stolniceanu, Constantin Volovat, Cristian Lungulescu, Dragos Scripcariu, Bogdan Mihail Cobzeanu, Cipriana Stefanescu, Cristina Grigorescu, Iolanda Augustin, Corina Lupascu Ursulescu, Cristian Constantin Volovat
Article Number: 535
Published online on: 23 March 2021

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Review

Teratogenic effect of isotretinoin in both fertile females and males (Review)

Carmen-Cristina Draghici, Raluca-Gabriela Miulescu, Răzvan-Cosmin Petca, Aida Petca, Mihai Cristian Dumitrașcu, Florica Șandru
Article Number: 534
Published online on: 23 March 2021

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Article Open Access

Cytokines, paraoxonase‑1, periostin and non‑invasive liver fibrosis scores in patients with non‑alcoholic fatty liver disease and persistently elevated aminotransferases: A pilot study

Mircea Vasile Milaciu, Lorena Ciumărnean, Daniela Maria Matei, Ștefan Cristian Vesa, Octavia Sabin, Ioana Corina Bocșan, Raluca Maria Pop, Vasile Negrean, Anca Dana Buzoianu, Monica Acalovschi
Article Number: 533
Published online on: 23 March 2021

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Case Report

Skin endometriosis: A case report and review of the literature

Andreea-Mariana Matei, Ana-Maria Draghici‑Ionescu, Mirela Cioplea, Sabina Andrada Zurac, Daniel Boda, Ioana Serban, Constantin Caruntu, Mihaela Adriana Ilie, László Fekete Gyula
Article Number: 532
Published online on: 23 March 2021

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Case Report Open Access

A nontraumatic myositis ossificans case of the forearm: Case report and literature review

Simona Pătru, Vlad Pădureanu, Dumitru Rădulescu, Radu Răzvan Mititelu, Rodica Pădureanu, Manuela Băcanoiu, Daniela Matei
Article Number: 531
Published online on: 23 March 2021

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Review Open Access

Gadolinium‑based contrast agents in neurofibromatosis type 1 (Review)

Florentina Năstase, Diana Sabina Radaschin, Elena Niculeț, Bogdan Ioan Stefanescu, Aurel Nechita, Draganescu Miruna, Liliana Baroiu, Arbune Manuela, Alin Laurenţiu Tatu
Article Number: 530
Published online on: 23 March 2021

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Article

Cardiovascular risk estimation in young patients with ankylosing spondylitis: A new model based on a prospective study in Constanta County, Romania

Mihaela Ionescu, Paris Ionescu, Adrian Paul Suceveanu, Anca Pantea Stoian, Ion Motofei, Valeriu Ardeleanu, Irinel-Raluca Parepa
Article Number: 529
Published online on: 22 March 2021

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Article Open Access

Influence of multidisciplinary therapeutic approach on fibromyalgia patients

Simona Pătru, Rodica Pădureanu, Florentina Dumitrescu, Vlad  Pădureanu, Dumitru Rădulescu, Diana Dragoi, Daniela Matei
Article Number: 528
Published online on: 22 March 2021

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Article Open Access

Vital dyes in macular hole surgery

Ioana Stella (Patoni) Popescu, Ovidiu Mușat, Simona Stanca, Corina Cristina (Coman) Cernat, Cristina Patoni, Serban Negru, Adrian Teodoru, Horia Feier, Ciprian Danielescu
Article Number: 527
Published online on: 22 March 2021

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Article Open Access

Role of combining neutrophil‑to‑lymphocyte ratio and pretreatment body mass index in predicting progression‑free survival in patients with non‑small cell lung cancer treated with nivolumab

Radu Dragomir, Adelina Silvana Dragomir, Alina Negru, Sorin Săftescu, Dorel Popovici, Michael Schenker, Raluca Lupușoru, Șerban Negru
Article Number: 526
Published online on: 22 March 2021

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Article Open Access

Symptom patterns and comparison of diagnostic methods in ragweed pollen allergy

Laura Haidar, Tudor-Paul Tamas, Frank Stolz, Raul Florian Petrisor Patrascu, Kuan-Wei Chen, Carmen Panaitescu
Article Number: 525
Published online on: 22 March 2021

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Article Open Access

Glycogen‑rich clear cell carcinoma of the breast with solid papillary pattern: Two cases with heterogeneous clinicopathological features

Tiberiu-Augustin Georgescu, Octavian Munteanu, Antonia-Carmen Lisievici, Tiberiu Tebeică, Dragoș Crețoiu, Oana Toader, Nicolae Suciu, Roxana Elena Bohîlțea
Article Number: 524
Published online on: 22 March 2021

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Article Open Access

Hypocalcemia: A possible risk factor for anastomotic leak in digestive surgery

Constantin Budin, Daniel Staniloaie, Danut Vasile, Alexandru Ilco, Daniela-Gabriela Balan, Popa Cristian Constantin, Ovidiu Stiru, Adrian Tulin, Mihaly Enyedi, Daniela Miricescu, Dragos Eugen Georgescu, Teodor Florin Georgescu, Dumitru Cristinel Badiu, Doina-Andrada Mihai
Article Number: 523
Published online on: 22 March 2021

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Article

First clinical experience with CDK4/6 inhibitors in breast cancer therapy

Ionut Marcel Cobec, Lavinia Moleriu, Aurica Elisabeta Moatar, Andreas Rempen
Article Number: 522
Published online on: 22 March 2021

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Review

Clinical spectrum of symptoms in cerebral Toxocariasis (Review)

Any Docu Axelerad, Alina Zorina Stroe, Anca Elena Gogu, Agneta Pusztai, Dragos Catalin Jianu, Duta Daniel, Daniel Docu Axelerad
Article Number: 521
Published online on: 22 March 2021

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Article Open Access

Predictive role of altered leptin, adiponectin and 3‑carboxy‑4‑methyl‑5‑propyl‑2‑furanpropanoic acid secretion in gestational diabetes mellitus

Andreea Roxana Florian, Gheorghe Cruciat, Raluca Maria Pop, Adelina Staicu, Muresan Daniel, Stamatian Florin
Article Number: 520
Published online on: 22 March 2021

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Article

Acute surgical abdomen during the COVID‑19 pandemic: Clinical and therapeutic challenges

Dragos Serban, Bogdan Socea, Cristinel Dumitru Badiu, Corneliu Tudor, Simona Andreea Balasescu, Dan Dumitrescu, Andra Maria Trotea, Radu Iulian Spataru, Geta Vancea, Ana Maria Dascalu, Ciprian Tanasescu
Article Number: 519
Published online on: 22 March 2021

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Article Open Access

Long non‑coding RNA receptor activator of nuclear factor‑κ B ligand promotes cisplatin resistance in non‑small cell lung cancer cells Retraction in /10.3892/etm.2024.12560

Zhongcheng Zhu, Xiaoyi Gong, Jing Li, Yufeng Shi, Mingyun Zhang
Article Number: 518
Published online on: 22 March 2021

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Correction Open Access

[Corrigendum] Methylation‑regulated ZNF545 inhibits growth of the p53‑mutant KYSE150 cell line by inducing p21 and Bax

Yu Fan, Yu Wang, Shaozhi Fu, Duan Liu, Sheng Lin
Article Number: 517
Published online on: 22 March 2021

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Article Open Access

Expression of nuclear factor erythroid‑2‑related factor 2, broad complex‑tramtrack‑bric a brac and Cap‘n’collar homology 1 and γ‑glutamic acid cysteine synthase in peripheral blood of patients with chronic obstructive pulmonary disease and its clinical significance

Dongrong Li, Ding Sun, Yehan Zhu
Article Number: 516
Published online on: 22 March 2021

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Article Open Access

Effects of histone H4 hyperacetylation on inhibiting MMP2 and MMP9 in human amniotic epithelial cells and in premature rupture of fetal membranes

Zhihui Song, Lili Yang, Wei Hu, Jianping Yi, Fumin Feng, Lingyan Zhu
Article Number: 515
Published online on: 22 March 2021

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Article Open Access

FBXW7 inhibits invasion, migration and angiogenesis in ovarian cancer cells by suppressing VEGF expression through inactivation of β‑catenin signaling

Liping Zhong, Yuefen Pan, Junjun Shen
Article Number: 514
Published online on: 19 March 2021

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Article Open Access

Association of antipsychotic use with raised eosinophil count

Konstantinos Tsamakis, Christoph Mueller, Ioannis Hortis, Maria Kallergi, Ioannis Tolos, Evangelos Alevyzakis, Nikolaos Siafakas, Andreas Ouranidis, Dimitrios Tsiptsios, Stylianos Kympouropoulos, Demetrios A. Spandidos, Nikolaos Smyrnis, Emmanouil Rizos
Article Number: 513
Published online on: 19 March 2021

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Article Open Access

Clinical significance of the long non‑coding RNA NEAT1/miR‑129‑5p axis in the diagnosis and prognosis for patients with chronic heart failure

Haohua Zhang, Nianli Zhang, Wenbin Jiang, Xiaoqin Lun
Article Number: 512
Published online on: 19 March 2021

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Article Open Access

Knockdown of lncRNA TTTY15 alleviates ischemia/reperfusion‑induced inflammation and apoptosis of PC12 cells by targeting miR‑766‑5p

Chenguang Hao, Shibao Chen
Article Number: 511
Published online on: 19 March 2021

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Article

Identification of a novel mutation in the C6 gene of a Han Chinese C6SD child with meningococcal disease

Ai-Qian Zhang, Yu-Xing Liu, Jie-Yuan Jin, Chen-Yu Wang, Liang-Liang Fan, Da-Bao Xu
Article Number: 510
Published online on: 19 March 2021

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Article Open Access

Increased thalamo‑cortical functional connectivity in patients with diabetic painful neuropathy: A resting‑state functional MRI study

Xiaomei Liu, Xianghong Xu, Cunnan Mao, Peng Zhang, Qing Zhang, Lanlan Jiang, Yuyin Yang, Jianhua Ma, Lei Ye, Kok-Onn Lee, Jindan Wu, Zhijian Yao
Article Number: 509
Published online on: 19 March 2021

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Article Open Access

Bioinformatics analysis of biomarkers of aristolochic acid‑induced early nephrotoxicity in embryonic stem cells

Li Wang, Shanshan Man, Yuhong Bian
Article Number: 508
Published online on: 18 March 2021

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Article Open Access

Inhibitory effect of miR-140-5p on doxorubicin resistance of hepatocellular carcinoma

Xiaojie Gao, Yan Jiang, Yingying Li
Article Number: 507
Published online on: 18 March 2021

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Article

Cytotoxic, chemosensitizing and radiosensitizing effects of curcumin based on thioredoxin system inhibition in breast cancer cells: 2D vs. 3D cell culture system

Shaymaa Essam El Feky, Magda Abdel Ghany Megahed, Nadia Ahmed Abd El Moneim, Ebtsam Rizq Zaher, Shadwa Ahmed Khamis, Lamiaa Mohamed Ahmed Ali
Article Number: 506
Published online on: 18 March 2021

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Article

Critical roles of Rad54 in tolerance to apigenin‑induced Top1‑mediated DNA damage

Zilu Zhao, Xiaohua Wu, Fang He, Cuifang Xiang, Xiaoyu Feng, Xin Bai, Xin Liu, Jingxia Zhao, Shunichi Takeda, Yong Qing
Article Number: 505
Published online on: 18 March 2021

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Article Open Access

Novel PRRT2 gene variants identified in paroxysmal kinesigenic dyskinesia and benign familial infantile epilepsy in Chinese families

Jialinzi He, Haiyun Tang, Chaorong Liu, Langzi Tan, Wenbiao Xiao, Bo Xiao, Hongyu Long, Lili Long
Article Number: 504
Published online on: 18 March 2021

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Article

Combination of HDE and BIIB021 efficiently inhibits cell proliferation and induces apoptosis via downregulating hTERT in myelodysplastic syndromes

Bo Wang, Jianping Jiang, Yun Zhang, Yingying Shen, Liqiang Wu, Siqi Tang, Shengyun Lin
Article Number: 503
Published online on: 17 March 2021

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Article Open Access

Increased sensitivity to TNF‑α promotes keloid fibroblast hyperproliferation by activating the NF‑κB, JNK and p38 MAPK pathways

Qijie Li, Fengrui Cheng, Kai Zhou, Lu Fang, Junliang Wu, Qingjie Xia, Ying Cen, Junjie Chen, Yong Qing
Article Number: 502
Published online on: 17 March 2021

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Article Open Access

Caffeine improves bladder function in diabetic rats via a neuroprotective effect

Jun Xue, Yadong Liu, Sichong Zhang, Liucheng Ding, Baixin Shen, Yunpeng Shao, Zhongqing Wei
Article Number: 501
Published online on: 17 March 2021

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Article Open Access

LncRNA XIST promotes inflammation by downregulating GRα expression in the adenoids of children with OSAHS

Zhen Zhou, Haifeng Ni, Yong Li, Bo Jiang
Article Number: 500
Published online on: 17 March 2021

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Review Open Access

MicroRNAs as crucial mediators in the pharmacological activities of triptolide (Review)

Kun Zhou, Yinxia Chang, Bo Han, Rui Li, Yanming Wei
Article Number: 499
Published online on: 17 March 2021

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Review Open Access

Rationality and necessity of vascular stapler application during liver resection (Review)

Er-Lei Zhang, Zhi-Yong Huang, Xiao-Ping Chen
Article Number: 498
Published online on: 17 March 2021

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Article Open Access

Knockdown of lncRNA SNHG14 alleviates LPS-induced inflammation and apoptosis of PC12 cells by regulating miR-181b-5p

Hui Jiang, Jie Ni, Yan Zheng, Yun Xu
Article Number: 497
Published online on: 17 March 2021

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Review Open Access

D‑ribose: Potential clinical applications in congestive heart failure and diabetes, and its complications (Review)

Shuai Li, Juanjing Wang, Yutian Xiao, Li Zhang, Jinren Fang, Nanyang Yang, Zhixia Zhang, Moussa Ide Nasser, Hui Qin
Article Number: 496
Published online on: 17 March 2021

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Article Open Access

Effects of lumican expression on the apoptosis of scleral fibroblasts: In vivo and in vitro experiments

Jinsong Wu, Yanzhi Zhao, Yanmei Fu, Shurong Li, Xu Zhang
Article Number: 495
Published online on: 17 March 2021

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Article Open Access

Development of a predictive model of growth hormone deficiency and idiopathic short stature in children

Mengdi Cong, Shi Qiu, Rongpin Li, Haiyan Sun, Lining Cong, Zhenzhou Hou
Article Number: 494
Published online on: 17 March 2021

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Article Open Access

Anti‑inflammatory and anti‑rheumatic activities in vitro of alkaloids separated from Aconitum soongoricum Stapf

Lijuan Zhang, Mukadaisi Siyiti, Jiang Zhang, Meiqi Yao, Feicui Zhao
Article Number: 493
Published online on: 17 March 2021

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Article Open Access

MicroRNA-29b inhibits human vascular smooth muscle cell proliferation via targeting the TGF-β/Smad3 signaling pathway

Lirong Li, Shaohua Ren, Xudong Hao, Zigang Zhen, Lei Ji, Hongming Ji
Article Number: 492
Published online on: 17 March 2021

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Article Open Access

Long non‑coding RNA SUMO1P3 promotes tumour progression by regulating cell proliferation and invasion in glioma

Danni Deng, Yi Mo, Lian Xue, Naiyuan Shao, Jie Cao
Article Number: 491
Published online on: 16 March 2021

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Article Open Access

Association of laboratory parameters and genetic polymorphisms with ischemic stroke in Chinese Han population

Jiayong Wang, Zujun Sun, Yibao Yang, Junlu Wu, Wenqiang Quan, Xingcai Chen, Peihua Ni, Dong Li
Article Number: 490
Published online on: 16 March 2021

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Article

Transfer RNA‑derived fragment tRF‑28‑QSZ34KRQ590K in plasma exosomes may be a potential biomarker for atopic dermatitis in pediatric patients

Li Meng, Long Jiang, Jian Chen, Hongjin Ren, Zhiqin Gao, Fei Wu, Yiyang Wen, Lianjuan Yang
Article Number: 489
Published online on: 16 March 2021

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Article Open Access

APC c.4621C>T variant causing Gardner's syndrome in a Han Chinese family may be inherited through maternal mosaicism

Decheng Cai, Fei He, Xiangmin Xu, Fu Xiong, Leitao Zhang
Article Number: 488
Published online on: 16 March 2021

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Article

Effects of anesthetic agents on inflammation in Caco‑2, HK‑2 and HepG2 cells

Weijing Li, Xiaoguang Hao, Yan Liu, Tong Tong, Hongmeng Xu, Li Jia
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Published online on: 16 March 2021

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Klotho overexpression suppresses apoptosis by regulating the Hsp70/Akt/Bad pathway in H9c2(2-1) cells

Jinpeng Hu, Bin Su, Xuewen Li, Yuming Li, Jihong Zhao
Article Number: 486
Published online on: 16 March 2021

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Severe acute respiratory syndrome coronavirus 2 ORF3a induces the expression of ACE2 in oral and pulmonary epithelial cells and the food supplement Vita Deyun® diminishes this effect

Adriana Aguilar-Lemarroy, Apolinar López-Uribe, José Sánchez-Corona, Luis Felipe Jave-suárez
Article Number: 485
Published online on: 16 March 2021

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Research advances in chimeric antigen receptor-modified T-cell therapy (Review)

Yuxi Luo, Guiqin Song, Shichu Liang, Feifei Li, Kang Liu
Article Number: 484
Published online on: 16 March 2021

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Preliminary analysis of immunoregulatory mechanism of hyperhomocysteinemia‑induced brain injury in Wistar‑Kyoto rats

Yu Zhang, Lin Wang, Xin Li, Jie Geng
Article Number: 483
Published online on: 16 March 2021

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Application of a three‑dimensional (3D) breast cancer model to study macrophage polarization

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IRF2BP2 prevents ox‑LDL‑induced inflammation and EMT in endothelial cells via regulation of KLF2

Yongri Jiang, Qiuling Shen
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Clinical therapeutic evaluation of vacuum sealing drainage and precise ultrasound‑guided debridement in the treatment of non‑lactational mastitis

Ruifu Chen, Junpeng Chen, Ajing Peng, Lihua Yang, Ruijuan Zhou
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MicroRNA‑23a‑5p regulates cell proliferation, migration and inflammation of TNF‑α‑stimulated human fibroblast‑like MH7A synoviocytes by targeting TLR4 in rheumatoid arthritis

Xiao Bao, Ling Ma, Chengsong He
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Published online on: 12 March 2021

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Genetic variations in the PSMA6 and PSMC6 proteasome genes are associated with multiple sclerosis and response to interferon‑β therapy in Latvians

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Published online on: 12 March 2021

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Long non‑coding RNA XIST promotes the proliferation of cardiac fibroblasts and the accumulation of extracellular matrix by sponging microRNA‑155‑5p

Hongbin Zhang, Jianfei Ma, Fei Liu, Jun Zhang
Article Number: 477
Published online on: 12 March 2021

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HOG1 has an essential role in the stress response, virulence and pathogenicity of Cryptococcus gattii

You-Ming Huang, Xiao-Hua Tao, Dan-Feng Xu, Yong  Yu, Yan Teng, Wen-Qing Xie, Yi-Bin Fan
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Effect of ticagrelor on acute kidney injury in septic rats and its underlying mechanism

Cheng Yu, Cui-Min Gao, Na Xie, Xiao-Qing Wang, Yu-Qing Ma
Article Number: 475
Published online on: 12 March 2021

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Negative pressure wound therapy enhances bone regeneration compared with conventional therapy in a rabbit radius gap‑healing model

Jin Zhu, Fangfang Wang, Li Yan, Junwen Wang, Mingzheng Wu, Rui Hu, Ying An
Article Number: 474
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Ginsenoside Rg2 protects cardiomyocytes against trastuzumab‑induced toxicity by inducing autophagy

Guang Liu, Xiaoyong Qi, Xingtao Li, Fangyi Sun
Article Number: 473
Published online on: 11 March 2021

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Retraction Open Access

[Retracted] Exposure to radiofrequency radiation increases the risk of breast cancer: A systematic review and meta‑analysis

Ya-Wen Shih, Anthony Paul O'Brien, Chin-Sheng Hung, Kee-Hsin Chen, Wen-Hsuan Hou, Hsiu-Ting Tsai
Article Number: 472
Published online on: 10 March 2021

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Article

Protective effects of gastrodin pretreatment on mouse hepatic ischemia‑reperfusion occurring through antioxidant and anti‑apoptotic mechanisms

Bo Sun, Jie Jiang, Xinyan Zhu, Dan Yang, Zhenyu Cui, Yu Zhang, Minbo Zhang, Yiting Qian, Ruilin Liu, Wenzhuo Yang
Article Number: 471
Published online on: 08 March 2021

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Proof‑of‑concept study investigating the role of S100P‑RAGE in nasopharyngeal carcinoma

Chengyu Wang, Xueqiao Wang, Angxuan Han, Yuhao Wang, Hui Jiang
Article Number: 470
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Effects of sevoflurane general anesthesia during early pregnancy on AIM2 expression in the hippocampus and parietal cortex of Sprague‑Dawley offspring rats

Yulin Zhu, Chao Lv, Jingying Liu, Shujun Shang, Wei Jing
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Quercetin suppresses apoptosis of chondrocytes induced by IL‑1β via inactivation of p38 MAPK signaling pathway

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Identification of miR‑145 as a regulator of the cardiomyocyte inflammatory response and oxidative stress under hyperglycemia

Wan Zheng, Tianfa Li, Junping Wei, Yuanyuan Zhang, Qi Zuo, Yun Lin
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Published online on: 08 March 2021

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Regulatory effect of mitoQ on the mtROS‑NLRP3 inflammasome pathway in leptin‑pretreated BEAS‑2 cells

Lei Chong, Haiyan Li, Lili Zhu, Gang Yu
Article Number: 466
Published online on: 08 March 2021

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Fibrinogen‑to‑albumin ratio predicts long‑term outcomes for patients with ST‑elevation myocardial infarction and multivessel disease: A prospective observational cohort study

Gao Liu, Chuan-Min Fan, Hao Guo, Wei-Na Fan, Ming-Liang Li, Guo-Xiong Cui
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Published online on: 08 March 2021

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Drug‑coated balloons in the treatment of acute myocardial infarction (Review)

Huilin Hu, Liang Shen
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BRAP2 inhibits the Ras/Raf/MEK and PI3K/Akt pathways in leukemia cells, thereby inducing apoptosis and inhibiting cell growth

Hiroharu Sakai, Isamu Shiina, Takahisa Shinomiya, Yukitoshi Nagahara
Article Number: 463
Published online on: 05 March 2021

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Graphene oxide induces dose‑dependent lung injury in rats by regulating autophagy

Lei Zhang, Shuge Ouyang, Hongbo Zhang, Mingke Qiu, Yuxin Dai, Shuqing Wang, Yang Wang, Jingmin Ou
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Glycyrrhizic acid restrains airway inflammation and remodeling in asthma via the TGF‑β1/Smad signaling pathway

Ziping Yao, Yanling Fu
Article Number: 461
Published online on: 03 March 2021

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4‑phenylbutyric acid mediates therapeutic effect in systemic lupus erythematosus: Observations in an experimental murine lupus model

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microRNA‑23 inhibits inflammation to alleviate rheumatoid arthritis via regulating CXCL12

Bo Gao, Guomin Sun, Yan Wang, Yaqin Geng, Lei Zhou, Xi Chen
Article Number: 459
Published online on: 03 March 2021

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Correlation between serum 25‑(OH)D3 level and immune imbalance of Th1/Th2 cytokines in patients with Hashimoto's thyroiditis and its effect on autophagy of human Hashimoto thyroid cells

Jing He, Yuanchun Li, Hui Li, Chunhui Zhang, Jian  Zhang, Xiaozhu Sun, Shumei Zheng
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Clinical diagnostic value of combined detection of IMA, D‑D and MCP‑1 in acute myocardial infarction

Mei Ding, Min Li, Hailing Yang
Article Number: 457
Published online on: 02 March 2021

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Congenital dyserythropoietic anemia and drug‑induced liver injury present as bland cholestasis: A case report

Yue Han, Yan Zhuang, Weiliang Tang, Lu Chen, Yejing Chen, Qiming Gong, Xinxin Zhang
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Article

Knockdown of long non‑coding RNA KCNQ1OT1 suppresses the progression of osteoarthritis by mediating the miR‑211‑5p/TCF4 axis in vitro

Dilihumaer Aili, Tong Wu, Yuan Gu, Ziyuan Chen, Wanchun Wang
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Actin-binding protein anillin promotes the progression of hepatocellular carcinoma in vitro and in mice Retraction in /10.3892/etm.2023.12120

Huanxia Jia, Zhenya Gao, Fang Yu, Hongfang Guo, Baoyu Li
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Hydrogen gas alleviates acute alcohol‑induced liver injury by inhibiting JNK activation

Yaxing Zhang, Mingmin Bi, Zifeng Chen, Min Dai, Ge  Zhou, Yuxuan Hu, Hongzhi Yang, Weibing Guan
Article Number: 453
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Adipose‑derived stem cell sheets combined with β‑tricalcium phosphate/collagen‑I fiber scaffold improve cell osteogenesis Corrigendum in /10.3892/etm.2025.12993

Yang Wang, Xiaojia Song, Rui Lei, Ning Zhang, Liangping Zhang, Wei Xiao, Jinghong Xu, Jun Lin
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Protective effects of peptide FK18 against neuro‑excitotoxicity in SH‑SY5Y cells

Shuyu Xiong, Mingming Ma, Yupeng Xu, Fang Wei, Qing Gu, Xiangui He, Xun Xu
Article Number: 451
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Role of the long non‑coding RNA HOTAIR/miR‑126 axis in an in vitro psoriasis model

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Meta‑analysis of laboratory results in patients with severe coronavirus disease 2019

Yun Huang, Yuyu Zhang, Lili Ma
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Magnolol may contribute to barrier function improvement on imiquimod‑induced psoriasis‑like dermatitis animal model via the downregulation of interleukin‑23

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Recent advances of glucocorticoids in the treatment of Duchenne muscular dystrophy (Review)

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Serum NT‑proBNP and TUG1 as novel biomarkers for elderly hypertensive patients with heart failure with preserved ejection fraction

Shuang Zhang, Rize Jin, Bi Li
Article Number: 446
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miR‑584 and miR‑146 are candidate biomarkers for acute respiratory distress syndrome

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Expression of histone deacetylase 2 in tracheal stenosis models and its relationship with tracheal granulation tissue proliferation

Zhenjie Huang, Peng Wei, Luoman Gan, Wentao Li, Tonghua Zeng, Caicheng Qin, Zhiyu Chen, Guangnan Liu
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Oleanolic acid inhibits osteosarcoma cell proliferation and invasion by suppressing the SOX9/Wnt1 signaling pathway

Xianming Chen, Yulin Zhang, Sen Zhang, Aiming Wang, Quanyin Du, Ziming Wang
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Clinical application of liver stiffness measurement in patients with cavernous transformation of portal vein

Yue Shen, Wei Ma, Ying Hang, Li-Li Liu, Wei Jiang, Sheng-Di Wu
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Published online on: 28 February 2021

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Acidic preconditioning reduces lipopolysaccharide‑induced acute lung injury by upregulating the expression of angiotensin‑converting enzyme 2

Guiyuan Yu, Yan Jiao, Jia-Jia Huang, Ming-Da Fan, Yu-Chen Hao, Ji-Zhong Han, Liangchao Qu
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Resveratrol protects against high glucose‑induced oxidative damage in human lens epithelial cells by activating autophagy

Pengzhi Chen, Zhenyu Yao, Zhihui He
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Published online on: 26 February 2021

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MicroRNA-383 promotes reactive oxygen species-induced autophagy via downregulating peroxiredoxin 3 in human glioma U87 cells

Zhou Xu, Xingruo Zeng, Mingchang Li, Jianming Liao, Qianxue Chen
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Laminar shear stress upregulates the expression of PPARs in vascular endothelial cells under high free fatty acid‑induced stress

Yu-Lin Wang, Chen-Te Chen, Che-Se Tung, Min-Chien Tsai
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EZH2 inhibitor GSK343 inhibits sepsis‑induced intestinal disorders

Dongyou Yue, Zhiying Wang, Yongan Yang, Zhenjun Hu, Ganping Luo, Fu Wang
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Published online on: 26 February 2021

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miR‑23a‑3p regulates the proliferation and apoptosis of human lens epithelial cells by targeting Bcl‑2 in an in vitro model of cataracts

Pengxiang Yao, Jian Jiang, Xiaoping Ma, Zhenzhong Chen, Yufang Hong, Yang Wu
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Protein tyrosine phosphatase receptor‑type O expression as a prognostic marker in patients with acute coronary syndrome undergoing percutaneous coronary intervention: A prospective study

Minghui Hao, Ming Guo, Rui Yan
Article Number: 435
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Effect of TNF‑α on the proliferation and osteogenesis of human periodontal mesenchymal stem cells

Yiting Cao, Yiwei Wang, Chenlin Li, Qian Jiang, Laikuan Zhu
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Estrogen administration attenuates post‑stroke depression by enhancing CREB/BDNF/TrkB signaling in the rat hippocampus

Huigang Jiang, Li Xiao, Kunlin Jin, Bei Shao
Article Number: 433
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Article

Remote ischemic preconditioning does not induce activation of Akt and STAT5 in the rat heart

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miR‑135a‑5p inhibitor protects glial cells against apoptosis via targeting SIRT1 in epilepsy

Ying Wang, Zhiquan Yang, Kai Zhang, Yi Wan, Yu Zhou, Zhuanyi Yang
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Dynamic study into autophagy and apoptosis during orthodontic tooth movement

Maoying Wang, Li Zhang, Fuwei Lin, Qian Zheng, Xiaomei Xu, Li Mei
Article Number: 430
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Anti‑inflammatory effects of Fritillaria thunbergii Miquel extracts in LPS‑stimulated murine macrophage RAW 264.7 cells

Jae-Hyun Kim, Minsun Kim, Sooyeon Hong, Boguen Kwon, Min Wook Song, Kwangchan Song, Eun-Young Kim, Hyuk-Sang Jung, Youngjoo Sohn
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Huanglian‑Houpo drug combination ameliorates H1N1‑induced mouse pneumonia via cytokines, antioxidant factors and TLR/MyD88/NF‑κB signaling pathways Retraction in /10.3892/etm.2025.12931

Li Zhang, Bei Zhang, Linjing Wang, Mingwu Lou, Yunxia Shen
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Protective effects of dexmedetomidine on the ischemic myocardium in patients undergoing rheumatic heart valve replacement surgery

Wei Chen, Yan Wang, Zhiguo Pan, Xiyuan Chen, Dihuan Luo, Haiying Wang
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Chlorogenic acid enhances autophagy by upregulating lysosomal function to protect against SH‑SY5Y cell injury induced by H2O2

Li-Juan Gao, Yuan Dai, Xiao-Qiong Li, Shi Meng, Zhan-Qiong Zhong, Shi-Jun Xu
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Kuwanon G protects HT22 cells from advanced glycation end product-induced damage

Wen-Jun Gan, Chen-Lin Gao, Wen-Qian Zhang, Jun-Ling Gu, Ting-Ting Zhao, Heng-Li Guo, Hua Zhou, Yong Xu, Li-Li Yu, Li-Fang Li, Ding-Kun Gui, You-Hua Xu
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Lidocaine suppresses the malignant behavior of gastric cancer cells via the c‑Met/c‑Src pathway

Wei Zeng, Ze Ting Xing, Mei Yun Tan, Yan Wen Wu, Chun Yuan Zhang
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Dysregulation of lncRNA SNHG1/miR‑145 axis affects the biological function of human carotid artery smooth muscle cells as a mechanism of carotid artery restenosis

Huanhuan Ma, Aiqin Dong
Article Number: 423
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Role of HDAC6 inhibition in sepsis‑induced acute respiratory distress syndrome (Review)

Qinghua Zhang, Yan Wang, Danhua Qu, Jinyan Yu, Junling Yang
Article Number: 422
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Effects of norepinephrine on colonic tight junction protein expression during heat stress

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Emodin induces collagen type I synthesis in Hs27 human dermal fibroblasts

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Radioprotective effects of centipedegrass extract on NIH‑3T3 fibroblasts via anti‑oxidative activity

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Distinctive gut microbial dysbiosis between chronic alcoholic fatty liver disease and metabolic‑associated fatty liver disease in mice

Kai Kang, Yue Sun, Dan Pan, Li-Xuan Sang, Ming-Jun Sun, Yi-Ling Li, Bing Chang
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Hyperresponsiveness of human gingival fibroblasts from patients with aggressive periodontitis against bacterial lipopolysaccharide

Xue Li, Xiaoxuan Wang, Qing-Xian Luan
Article Number: 417
Published online on: 25 February 2021

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Role of targeted and universal mupirocin‑based decolonization for preventing surgical‑site infections in patients undergoing cardiothoracic surgery: A systematic review and meta‑analysis

Li Wang, Qi Ji, Xiaoyan Hu
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Mutational landscape and potential therapeutic targets for sporadic pancreatic neuroendocrine tumors based on target next‑generation sequencing

Kailian Zheng, Tao Liu, Jiangman Zhao, Peng Meng, Yun Bian, Chenming Ni, Huan Wang, Yaqi Pan, Shouxin Wu, Hui Jiang, Gang Jin
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miR‑130a‑3p promotes cell proliferation and invasion by targeting estrogen receptor α and androgen receptor in cervical cancer

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Underlying mechanisms of the effect of minocycline against Candida albicans biofilms

Li Zou, Zhao Mei, Tao Guan, Bo Zhang, Qun Deng
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Role of vasodilator‑stimulated phosphoprotein in RANKL‑differentiated murine macrophage RAW264.7 cells: Modulation of NF‑κB, c‑Fos and NFATc1 transcription factors

Hao Hu, Chao Li, Haitao Zhang, Gang Wu, Yong Huang
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Adiposity indices and bone health amongst Malaysian adults: Evidence from a cross‑sectional study

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Ginsenoside Re attenuates homocysteine‑induced endothelial cell ferroptosis through upregulation of GPX4/xCT signaling

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[Corrigendum] Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/β‑catenin signaling pathway

Yun Yi, Bing Liao, Ziwen Zheng, Xiaorong Yang, Yunsheng Yang, Yanfang Zhou, Buzhen Tan, Xinfeng Yang
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Identification of early diagnostic biomarkers in venous thromboembolism: A bioinformatic analysis based on crosstalk between pyroptosis and venous thromboembolism

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[Retracted] Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
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Atorvastatin ameliorates chronic subdural hematomas by interrupting the ‘chronic subdural hematoma cycle’ via inhibition of the inflammatory response

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Diagnosis and treatment of invasive fungal disease in children with hematological malignancies after chemotherapy: Challenges and strategies (Review)

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Venetoclax combined with azacitidine for treatment of a blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

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[Retracted] miRNA‑30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene

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[Retracted] MicroRNA‑490‑3p regulates cell proliferation and apoptosis in gastric cancer via direct targeting of AKT1

Hong Yu, Jianying Sun, Shaochang Jiang, Ying Xu
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A comparison of bridging external fixation vs. combined external fixation for preventing radial height loss in older patients with distal radius fractures

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Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3‑kinase/protein kinase B signaling pathway

Bin Yan, Aikepaer Wubuli, Yidong Liu, Xin Wang
Article Number: 7
Published online on: 27 October 2025

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Diagnostic significance of the checkpoint kinase 1 gene in high‑grade gastroenteropancreatic neuroendocrine neoplasms

Na Li, Jianduo An, Yanping Hu
Article Number: 6
Published online on: 24 October 2025

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Retraction Open Access

[Retracted] Establishment of ApoE‑knockout mouse model of preeclampsia and relevant mechanisms

Wenjuan Sun, Baoxia Cui, Fanzhen Hong, Yongping Xu
Article Number: 5
Published online on: 23 October 2025

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Investigating the association between uterine fibroids and weight‑bearing joint osteoarthritis based on a bidirectional Mendelian randomization study

Xiao Ma, Jingjing Ma, Han Zhang, Xiaodong Jia, Tianrui Wang, Shanshan Ma, Yingze Zhang
Article Number: 4
Published online on: 21 October 2025

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Epimedin C: A promising neuroprotective agent that can participate in mediating the JNK/Nrf2/HO‑1 signaling pathway to prevent neurodegenerative diseases

Chao Cong, Xuan-Ling Li, Guang-Yao Lin, Lian-Wei Xu
Article Number: 3
Published online on: 21 October 2025

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Application of pleural effusion cell blocks for immunohistochemistry and EGFR gene mutation testing for advanced lung cancer

Shouxiang Zhao, Yuhong Liu, Tao Wang, Ying Li, Ze Chen, Xiaoshan Cai
Article Number: 2
Published online on: 21 October 2025

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Correction Open Access

[Corrigendum] Evaluation of the inhibitory effects of vaginal microorganisms on sperm motility in vitro

Huan Wang, Tingtao Chen, Yidan Chen, Tao Luo, Buzhen Tan, Houyang Chen, Hongbo Xin
Article Number: 1
Published online on: 16 October 2025

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February-2026 Volume 31 Issue 2

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Case Report Open Access

Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

Chenao Wang, Yufeng Liu, Yaqing Liu, Baicheng Li, Xingdong Hou, Bowei Lu, Zhao Chen, Shili Ning
Article Number: 48
Published online on: 05 December 2025

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Calcifying fibrous tumours of the diaphragm: A case report and literature review

Sijia Guo, Wenya Han, Lingling Yuan, Hansheng Wang, Ge Cheng, Yaxin Tuo, Chuanyong Xiao, Jialong Guo, Meifang Wang
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Published online on: 05 December 2025

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Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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Correction Open Access

[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Review

Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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Case Report

A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model

Omer Cennet, Akbar Hajiyev, Burcin Şener, Filiz Akbiyik, Cenk Sökmensüer, Osman Abbasoglu
Article Number: 40
Published online on: 01 December 2025

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The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

Xuemei Sun, Min Yang, Lingling Wan, Hua Zhong
Article Number: 39
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 38
Published online on: 01 December 2025

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Effects of small incision lenticule extraction and femtosecond laser‑assisted in situ keratomileusis on choroidal thickness and blood flow density in patients with myopia

Shirui Yang, Tiantian Qian, Min Tang, Jing Zhang, Jie Hou, Yahui Dong, Yulin Lei
Article Number: 37
Published online on: 01 December 2025

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Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

Yanru Guo, Zhi Li, Yiqun Zhang, Zhijuan Pan, Jiajia Sun, Ying Zhang, Shuting Chang, Zhiping Guo
Article Number: 36
Published online on: 01 December 2025

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Patients with sickle cell disease and asthma have a higher risk for acute chest syndrome: A systematic review and meta‑analysis of observational studies

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 35
Published online on: 28 November 2025

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Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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Outcomes of anti‑VEGF therapy compared with conventional interventions in diabetic retinopathy management

Yong Guo, Rui Yang, Yan Li, Chenjun Guo, Houcheng Liang
Article Number: 33
Published online on: 28 November 2025

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Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
Article Number: 32
Published online on: 28 November 2025

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Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

Miaomiao Yang, Yongqing Ma, Xiaofu Qu, Zhe Qu, Jiang Sun
Article Number: 31
Published online on: 25 November 2025

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Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

Lu Mo, Ruichen Liang, Xianyong Wang, Zhiwei Xiao, Zhongxun Wu, Lihong Chen
Article Number: 30
Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

Wei Liu, Shengnan Dong, Yumei Li, Lihong Shi, Wei Zhou, Yingling Liu, Jie Liu, Yazhong Ji
Article Number: 29
Published online on: 24 November 2025

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