Journal Articles

Review Open Access

Understanding the genetics and neurobiological pathways behind addiction (Review)

Alexandra Popescu, Maria Marian, Ana Miruna Drăgoi, Radu-Virgil Costea

Article Number: 544 Published online on: 23 March 2021
Article

Abdominal paraaortic paraganglioma: Management of intraoperative hemodynamic emergencies during elective resection procedures (A case presentation)

Ovidiu Stiru, Anca Dragan, Cristina Adamache, Petru Razvan Dragulescu, Carmen Stiru, Adrian Tulin, Nicolae Bacalbasa, Irina Balescu, Camelia Diaconu, Roxana Carmen Geana, Cornel Savu, Vlad Anton Iliescu

Article Number: 543 Published online on: 23 March 2021
Article

Assessing the values of circulating immune complexes in multiple sclerosis patients following immunomodulator or corticosteroid treatment

Any Docu Axelerad, Alina Zorina Stroe, Anca Elena Gogu, Daniel Docu Axelerad

Article Number: 542 Published online on: 23 March 2021
Article

Orthopedic surgery approach with uncemented metallic prosthesis in knee osteoarthritis increases the quality of life of young patients

Bogdan Uivaraseanu, Simona Bungau, Delia Mirela Tit, Tapan Behl, Teodor Andrei Maghiar, Octavian Maghiar, Carmen Pantis, Dana Carmen Zaha, Jenel M. Patrascu

Article Number: 541 Published online on: 23 March 2021
Review Open Access

PI3K/AKT/mTOR signalling pathway involvement in renal cell carcinoma pathogenesis (Review)

Daniela Miricescu, Daniela Gabriela Balan, Adrian Tulin, Ovidiu Stiru, Ileana Adela Vacaroiu, Doina Andrada Mihai, Cristian Constantin Popa, Raluca Ioana Papacocea, Mihaly Enyedi, Nedelea Andrei Sorin, Guenadiy Vatachki, Dragoș Eugen Georgescu, Adriana Elena Nica, Constantin Stefani

Article Number: 540 Published online on: 23 March 2021
Review Open Access

Impact of adipose tissue in chronic kidney disease development (Review)

Daniela Miricescu, Daniela Gabriela Balan, Adrian Tulin, Ovidiu Stiru, Ileana Adela Vacaroiu, Doina Andrada Mihai, Cristian Constantin Popa, Mihaly Enyedi, Andrei Sorin Nedelea, Adriana Elena Nica, Constantin Stefani

Article Number: 539 Published online on: 23 March 2021
Article

Discrepancy in results between dipstick urinalysis and urine sediment microscopy

Anca Bacârea, Gyula László Fekete, Bianca Liana Grigorescu, Vladimir Constantin Bacârea

Article Number: 538 Published online on: 23 March 2021
Article

Practical safety in the diagnosis and treatment of congenital isolated tracheoesophageal fistula

Radu-Iulian Spataru, Dan-Alexandru Iozsa, Mircea Ovidiu Denis Lupusoru, Dragos Serban, Catalin Cirstoveanu

Article Number: 537 Published online on: 23 March 2021
Case Report Open Access

Unexpected diagnosis for a gastric polyp: Granular cell tumor: Case report and review of the literature

Sorina Maria Taban, Robert Alexandru Barna, Alis Liliana Carmen Dema, Iulia Maria Ratiu, Oana Popa, Andrei Dorel Plopeanu

Article Number: 536 Published online on: 23 March 2021
Review Open Access

Nanomedicine to modulate immunotherapy in cutaneous melanoma (Review)

Simona Ruxandra Volovat, Serban Negru, Cati Raluca Stolniceanu, Constantin Volovat, Cristian Lungulescu, Dragos Scripcariu, Bogdan Mihail Cobzeanu, Cipriana Stefanescu, Cristina Grigorescu, Iolanda Augustin, Corina Lupascu Ursulescu, Cristian Constantin Volovat

Article Number: 535 Published online on: 23 March 2021
Review

Teratogenic effect of isotretinoin in both fertile females and males (Review)

Carmen-Cristina Draghici, Raluca-Gabriela Miulescu, Răzvan-Cosmin Petca, Aida Petca, Mihai Cristian Dumitrașcu, Florica Șandru

Article Number: 534 Published online on: 23 March 2021
Article Open Access

Cytokines, paraoxonase‑1, periostin and non‑invasive liver fibrosis scores in patients with non‑alcoholic fatty liver disease and persistently elevated aminotransferases: A pilot study

Mircea Vasile Milaciu, Lorena Ciumărnean, Daniela Maria Matei, Ștefan Cristian Vesa, Octavia Sabin, Ioana Corina Bocșan, Raluca Maria Pop, Vasile Negrean, Anca Dana Buzoianu, Monica Acalovschi

Article Number: 533 Published online on: 23 March 2021
Case Report

Skin endometriosis: A case report and review of the literature

Andreea-Mariana Matei, Ana-Maria Draghici‑Ionescu, Mirela Cioplea, Sabina Andrada Zurac, Daniel Boda, Ioana Serban, Constantin Caruntu, Mihaela Adriana Ilie, László Fekete Gyula

Article Number: 532 Published online on: 23 March 2021
Case Report Open Access

A nontraumatic myositis ossificans case of the forearm: Case report and literature review

Simona Pătru, Vlad Pădureanu, Dumitru Rădulescu, Radu Răzvan Mititelu, Rodica Pădureanu, Manuela Băcanoiu, Daniela Matei

Article Number: 531 Published online on: 23 March 2021
Review Open Access

Gadolinium‑based contrast agents in neurofibromatosis type 1 (Review)

Florentina Năstase, Diana Sabina Radaschin, Elena Niculeț, Bogdan Ioan Stefanescu, Aurel Nechita, Draganescu Miruna, Liliana Baroiu, Arbune Manuela, Alin Laurenţiu Tatu

Article Number: 530 Published online on: 23 March 2021
Article

Cardiovascular risk estimation in young patients with ankylosing spondylitis: A new model based on a prospective study in Constanta County, Romania

Mihaela Ionescu, Paris Ionescu, Adrian Paul Suceveanu, Anca Pantea Stoian, Ion Motofei, Valeriu Ardeleanu, Irinel-Raluca Parepa

Article Number: 529 Published online on: 22 March 2021
Article Open Access

Influence of multidisciplinary therapeutic approach on fibromyalgia patients

Simona Pătru, Rodica Pădureanu, Florentina Dumitrescu, Vlad  Pădureanu, Dumitru Rădulescu, Diana Dragoi, Daniela Matei

Article Number: 528 Published online on: 22 March 2021
Article Open Access

Vital dyes in macular hole surgery

Ioana Stella (Patoni) Popescu, Ovidiu Mușat, Simona Stanca, Corina Cristina (Coman) Cernat, Cristina Patoni, Serban Negru, Adrian Teodoru, Horia Feier, Ciprian Danielescu

Article Number: 527 Published online on: 22 March 2021
Article Open Access

Role of combining neutrophil‑to‑lymphocyte ratio and pretreatment body mass index in predicting progression‑free survival in patients with non‑small cell lung cancer treated with nivolumab

Radu Dragomir, Adelina Silvana Dragomir, Alina Negru, Sorin Săftescu, Dorel Popovici, Michael Schenker, Raluca Lupușoru, Șerban Negru

Article Number: 526 Published online on: 22 March 2021
Article Open Access

Symptom patterns and comparison of diagnostic methods in ragweed pollen allergy

Laura Haidar, Tudor-Paul Tamas, Frank Stolz, Raul Florian Petrisor Patrascu, Kuan-Wei Chen, Carmen Panaitescu

Article Number: 525 Published online on: 22 March 2021
Article Open Access

Glycogen‑rich clear cell carcinoma of the breast with solid papillary pattern: Two cases with heterogeneous clinicopathological features

Tiberiu-Augustin Georgescu, Octavian Munteanu, Antonia-Carmen Lisievici, Tiberiu Tebeică, Dragoș Crețoiu, Oana Toader, Nicolae Suciu, Roxana Elena Bohîlțea

Article Number: 524 Published online on: 22 March 2021
Article Open Access

Hypocalcemia: A possible risk factor for anastomotic leak in digestive surgery

Constantin Budin, Daniel Staniloaie, Danut Vasile, Alexandru Ilco, Daniela-Gabriela Balan, Popa Cristian Constantin, Ovidiu Stiru, Adrian Tulin, Mihaly Enyedi, Daniela Miricescu, Dragos Eugen Georgescu, Teodor Florin Georgescu, Dumitru Cristinel Badiu, Doina-Andrada Mihai

Article Number: 523 Published online on: 22 March 2021
Article

First clinical experience with CDK4/6 inhibitors in breast cancer therapy

Ionut Marcel Cobec, Lavinia Moleriu, Aurica Elisabeta Moatar, Andreas Rempen

Article Number: 522 Published online on: 22 March 2021
Review

Clinical spectrum of symptoms in cerebral Toxocariasis (Review)

Any Docu Axelerad, Alina Zorina Stroe, Anca Elena Gogu, Agneta Pusztai, Dragos Catalin Jianu, Duta Daniel, Daniel Docu Axelerad

Article Number: 521 Published online on: 22 March 2021
Article Open Access

Predictive role of altered leptin, adiponectin and 3‑carboxy‑4‑methyl‑5‑propyl‑2‑furanpropanoic acid secretion in gestational diabetes mellitus

Andreea Roxana Florian, Gheorghe Cruciat, Raluca Maria Pop, Adelina Staicu, Muresan Daniel, Stamatian Florin

Article Number: 520 Published online on: 22 March 2021
Article

Acute surgical abdomen during the COVID‑19 pandemic: Clinical and therapeutic challenges

Dragos Serban, Bogdan Socea, Cristinel Dumitru Badiu, Corneliu Tudor, Simona Andreea Balasescu, Dan Dumitrescu, Andra Maria Trotea, Radu Iulian Spataru, Geta Vancea, Ana Maria Dascalu, Ciprian Tanasescu

Article Number: 519 Published online on: 22 March 2021
Article Open Access

Long non‑coding RNA receptor activator of nuclear factor‑κ B ligand promotes cisplatin resistance in non‑small cell lung cancer cells

Zhongcheng Zhu, Xiaoyi Gong, Jing Li, Yufeng Shi, Mingyun Zhang

Article Number: 518 Published online on: 22 March 2021
Correction Open Access

[Corrigendum] Methylation‑regulated ZNF545 inhibits growth of the p53‑mutant KYSE150 cell line by inducing p21 and Bax

Yu Fan, Yu Wang, Shaozhi Fu, Duan Liu, Sheng Lin

Article Number: 517 Published online on: 22 March 2021
Article Open Access

Effects of histone H4 hyperacetylation on inhibiting MMP2 and MMP9 in human amniotic epithelial cells and in premature rupture of fetal membranes

Zhihui Song, Lili Yang, Wei Hu, Jianping Yi, Fumin Feng, Lingyan Zhu

Article Number: 515 Published online on: 22 March 2021
Article Open Access

Association of antipsychotic use with raised eosinophil count

Konstantinos Tsamakis, Christoph Mueller, Ioannis Hortis, Maria Kallergi, Ioannis Tolos, Evangelos Alevyzakis, Nikolaos Siafakas, Andreas Ouranidis, Dimitrios Tsiptsios, Stylianos Kympouropoulos, Demetrios A. Spandidos, Nikolaos Smyrnis, Emmanouil Rizos

Article Number: 513 Published online on: 19 March 2021
Article Open Access

Clinical significance of the long non‑coding RNA NEAT1/miR‑129‑5p axis in the diagnosis and prognosis for patients with chronic heart failure

Haohua Zhang, Nianli Zhang, Wenbin Jiang, Xiaoqin Lun

Article Number: 512 Published online on: 19 March 2021
Article

Identification of a novel mutation in the C6 gene of a Han Chinese C6SD child with meningococcal disease

Ai-Qian Zhang, Yu-Xing Liu, Jie-Yuan Jin, Chen-Yu Wang, Liang-Liang Fan, Da-Bao Xu

Article Number: 510 Published online on: 19 March 2021
Article Open Access

Increased thalamo‑cortical functional connectivity in patients with diabetic painful neuropathy: A resting‑state functional MRI study

Xiaomei Liu, Xianghong Xu, Cunnan Mao, Peng Zhang, Qing Zhang, Lanlan Jiang, Yuyin Yang, Jianhua Ma, Lei Ye, Kok-Onn Lee, Jindan Wu, Zhijian Yao

Article Number: 509 Published online on: 19 March 2021
Article Open Access

Bioinformatics analysis of biomarkers of aristolochic acid‑induced early nephrotoxicity in embryonic stem cells

Li Wang, Shanshan Man, Yuhong Bian

Article Number: 508 Published online on: 18 March 2021
Article Open Access

Inhibitory effect of miR-140-5p on doxorubicin resistance of hepatocellular carcinoma

Xiaojie Gao, Yan Jiang, Yingying Li

Article Number: 507 Published online on: 18 March 2021
Article

Cytotoxic, chemosensitizing and radiosensitizing effects of curcumin based on thioredoxin system inhibition in breast cancer cells: 2D vs. 3D cell culture system

Shaymaa Essam El Feky, Magda Abdel Ghany Megahed, Nadia Ahmed Abd El Moneim, Ebtsam Rizq Zaher, Shadwa Ahmed Khamis, Lamiaa Mohamed Ahmed Ali

Article Number: 506 Published online on: 18 March 2021
Article

Critical roles of Rad54 in tolerance to apigenin‑induced Top1‑mediated DNA damage

Zilu Zhao, Xiaohua Wu, Fang He, Cuifang Xiang, Xiaoyu Feng, Xin Bai, Xin Liu, Jingxia Zhao, Shunichi Takeda, Yong Qing

Article Number: 505 Published online on: 18 March 2021
Article Open Access

Novel PRRT2 gene variants identified in paroxysmal kinesigenic dyskinesia and benign familial infantile epilepsy in Chinese families

Jialinzi He, Haiyun Tang, Chaorong Liu, Langzi Tan, Wenbiao Xiao, Bo Xiao, Hongyu Long, Lili Long

Article Number: 504 Published online on: 18 March 2021
Article

Combination of HDE and BIIB021 efficiently inhibits cell proliferation and induces apoptosis via downregulating hTERT in myelodysplastic syndromes

Bo Wang, Jianping Jiang, Yun Zhang, Yingying Shen, Liqiang Wu, Siqi Tang, Shengyun Lin

Article Number: 503 Published online on: 17 March 2021
Article Open Access

Increased sensitivity to TNF‑α promotes keloid fibroblast hyperproliferation by activating the NF‑κB, JNK and p38 MAPK pathways

Qijie Li, Fengrui Cheng, Kai Zhou, Lu Fang, Junliang Wu, Qingjie Xia, Ying Cen, Junjie Chen, Yong Qing

Article Number: 502 Published online on: 17 March 2021
Article Open Access

Caffeine improves bladder function in diabetic rats via a neuroprotective effect

Jun Xue, Yadong Liu, Sichong Zhang, Liucheng Ding, Baixin Shen, Yunpeng Shao, Zhongqing Wei

Article Number: 501 Published online on: 17 March 2021
Article Open Access

LncRNA XIST promotes inflammation by downregulating GRα expression in the adenoids of children with OSAHS

Zhen Zhou, Haifeng Ni, Yong Li, Bo Jiang

Article Number: 500 Published online on: 17 March 2021
Review Open Access

MicroRNAs as crucial mediators in the pharmacological activities of triptolide (Review)

Kun Zhou, Yinxia Chang, Bo Han, Rui Li, Yanming Wei

Article Number: 499 Published online on: 17 March 2021
Review Open Access

Rationality and necessity of vascular stapler application during liver resection (Review)

Er-Lei Zhang, Zhi-Yong Huang, Xiao-Ping Chen

Article Number: 498 Published online on: 17 March 2021
Article Open Access

Knockdown of lncRNA SNHG14 alleviates LPS-induced inflammation and apoptosis of PC12 cells by regulating miR-181b-5p

Hui Jiang, Jie Ni, Yan Zheng, Yun Xu

Article Number: 497 Published online on: 17 March 2021
Review Open Access

D‑ribose: Potential clinical applications in congestive heart failure and diabetes, and its complications (Review)

Shuai Li, Juanjing Wang, Yutian Xiao, Li Zhang, Jinren Fang, Nanyang Yang, Zhixia Zhang, Moussa Ide Nasser, Hui Qin

Article Number: 496 Published online on: 17 March 2021
Article Open Access

Effects of lumican expression on the apoptosis of scleral fibroblasts: In vivo and in vitro experiments

Jinsong Wu, Yanzhi Zhao, Yanmei Fu, Shurong Li, Xu Zhang

Article Number: 495 Published online on: 17 March 2021
Article Open Access

Development of a predictive model of growth hormone deficiency and idiopathic short stature in children

Mengdi Cong, Shi Qiu, Rongpin Li, Haiyan Sun, Lining Cong, Zhenzhou Hou

Article Number: 494 Published online on: 17 March 2021
Article Open Access

Anti‑inflammatory and anti‑rheumatic activities in vitro of alkaloids separated from Aconitum soongoricum Stapf

Lijuan Zhang, Mukadaisi Siyiti, Jiang Zhang, Meiqi Yao, Feicui Zhao

Article Number: 493 Published online on: 17 March 2021
Article Open Access

MicroRNA-29b inhibits human vascular smooth muscle cell proliferation via targeting the TGF-β/Smad3 signaling pathway

Lirong Li, Shaohua Ren, Xudong Hao, Zigang Zhen, Lei Ji, Hongming Ji

Article Number: 492 Published online on: 17 March 2021
Article Open Access

Long non‑coding RNA SUMO1P3 promotes tumour progression by regulating cell proliferation and invasion in glioma

Danni Deng, Yi Mo, Lian Xue, Naiyuan Shao, Jie Cao

Article Number: 491 Published online on: 16 March 2021
Article Open Access

Association of laboratory parameters and genetic polymorphisms with ischemic stroke in Chinese Han population

Jiayong Wang, Zujun Sun, Yibao Yang, Junlu Wu, Wenqiang Quan, Xingcai Chen, Peihua Ni, Dong Li

Article Number: 490 Published online on: 16 March 2021
Article

Transfer RNA‑derived fragment tRF‑28‑QSZ34KRQ590K in plasma exosomes may be a potential biomarker for atopic dermatitis in pediatric patients

Li Meng, Long Jiang, Jian Chen, Hongjin Ren, Zhiqin Gao, Fei Wu, Yiyang Wen, Lianjuan Yang

Article Number: 489 Published online on: 16 March 2021
Article Open Access

APC c.4621C>T variant causing Gardner's syndrome in a Han Chinese family may be inherited through maternal mosaicism

Decheng Cai, Fei He, Xiangmin Xu, Fu Xiong, Leitao Zhang

Article Number: 488 Published online on: 16 March 2021
Article

Effects of anesthetic agents on inflammation in Caco‑2, HK‑2 and HepG2 cells

Weijing Li, Xiaoguang Hao, Yan Liu, Tong Tong, Hongmeng Xu, Li Jia

Article Number: 487 Published online on: 16 March 2021
Article Open Access

Klotho overexpression suppresses apoptosis by regulating the Hsp70/Akt/Bad pathway in H9c2(2-1) cells

Jinpeng Hu, Bin Su, Xuewen Li, Yuming Li, Jihong Zhao

Article Number: 486 Published online on: 16 March 2021
Article Open Access

Severe acute respiratory syndrome coronavirus 2 ORF3a induces the expression of ACE2 in oral and pulmonary epithelial cells and the food supplement Vita Deyun® diminishes this effect

Adriana Aguilar-Lemarroy, Apolinar López-Uribe, José Sánchez-Corona, Luis Felipe Jave-suárez

Article Number: 485 Published online on: 16 March 2021
Review Open Access

Research advances in chimeric antigen receptor-modified T-cell therapy (Review)

Yuxi Luo, Guiqin Song, Shichu Liang, Feifei Li, Kang Liu

Article Number: 484 Published online on: 16 March 2021
Article Open Access

Preliminary analysis of immunoregulatory mechanism of hyperhomocysteinemia‑induced brain injury in Wistar‑Kyoto rats

Yu Zhang, Lin Wang, Xin Li, Jie Geng

Article Number: 483 Published online on: 16 March 2021
Article Open Access

Application of a three‑dimensional (3D) breast cancer model to study macrophage polarization

Agata Golabek, Mariusz Kaczmarek, Ewelina Dondajewska, Kosma Sakrajda, Andrzej Mackiewicz, Hanna Dams‑kozlowska

Article Number: 482 Published online on: 16 March 2021
Article Open Access

IRF2BP2 prevents ox‑LDL‑induced inflammation and EMT in endothelial cells via regulation of KLF2

Yongri Jiang, Qiuling Shen

Article Number: 481 Published online on: 12 March 2021
Article Open Access

Clinical therapeutic evaluation of vacuum sealing drainage and precise ultrasound‑guided debridement in the treatment of non‑lactational mastitis

Ruifu Chen, Junpeng Chen, Ajing Peng, Lihua Yang, Ruijuan Zhou

Article Number: 480 Published online on: 12 March 2021
Article Open Access

Genetic variations in the PSMA6 and PSMC6 proteasome genes are associated with multiple sclerosis and response to interferon‑β therapy in Latvians

Natalia Paramonova, Jolanta Kalnina, Kristine Dokane, Kristine  Dislere, Ilva Trapina, Tatjana Sjakste, Nikolajs Sjakste

Article Number: 478 Published online on: 12 March 2021
Article Open Access

Long non‑coding RNA XIST promotes the proliferation of cardiac fibroblasts and the accumulation of extracellular matrix by sponging microRNA‑155‑5p

Hongbin Zhang, Jianfei Ma, Fei Liu, Jun Zhang

Article Number: 477 Published online on: 12 March 2021
Article Open Access

HOG1 has an essential role in the stress response, virulence and pathogenicity of Cryptococcus gattii

You-Ming Huang, Xiao-Hua Tao, Dan-Feng Xu, Yong  Yu, Yan Teng, Wen-Qing Xie, Yi-Bin Fan

Article Number: 476 Published online on: 12 March 2021
Article Open Access

Effect of ticagrelor on acute kidney injury in septic rats and its underlying mechanism

Cheng Yu, Cui-Min Gao, Na Xie, Xiao-Qing Wang, Yu-Qing Ma

Article Number: 475 Published online on: 12 March 2021
Article Open Access

Negative pressure wound therapy enhances bone regeneration compared with conventional therapy in a rabbit radius gap‑healing model

Jin Zhu, Fangfang Wang, Li Yan, Junwen Wang, Mingzheng Wu, Rui Hu, Ying An

Article Number: 474 Published online on: 12 March 2021
Article Open Access

Ginsenoside Rg2 protects cardiomyocytes against trastuzumab‑induced toxicity by inducing autophagy

Guang Liu, Xiaoyong Qi, Xingtao Li, Fangyi Sun

Article Number: 473 Published online on: 11 March 2021
Retraction Open Access

[Retracted] Exposure to radiofrequency radiation increases the risk of breast cancer: A systematic review and meta‑analysis

Ya-Wen Shih, Anthony Paul O'Brien, Chin-Sheng Hung, Kee-Hsin Chen, Wen-Hsuan Hou, Hsiu-Ting Tsai

Article Number: 472 Published online on: 10 March 2021
Article

Protective effects of gastrodin pretreatment on mouse hepatic ischemia‑reperfusion occurring through antioxidant and anti‑apoptotic mechanisms

Bo Sun, Jie Jiang, Xinyan Zhu, Dan Yang, Zhenyu Cui, Yu Zhang, Minbo Zhang, Yiting Qian, Ruilin Liu, Wenzhuo Yang

Article Number: 471 Published online on: 08 March 2021
Article Open Access

Proof‑of‑concept study investigating the role of S100P‑RAGE in nasopharyngeal carcinoma

Chengyu Wang, Xueqiao Wang, Angxuan Han, Yuhao Wang, Hui Jiang

Article Number: 470 Published online on: 08 March 2021
Article Open Access

Effects of sevoflurane general anesthesia during early pregnancy on AIM2 expression in the hippocampus and parietal cortex of Sprague‑Dawley offspring rats

Yulin Zhu, Chao Lv, Jingying Liu, Shujun Shang, Wei Jing

Article Number: 469 Published online on: 08 March 2021
Article Open Access

Quercetin suppresses apoptosis of chondrocytes induced by IL‑1β via inactivation of p38 MAPK signaling pathway

Xiang-Peng Wang, Wen-Peng Xie, Yi-Fei Bi, Bao-An Wang, Hong-Bo Song, Shi-Lu Wang, Rong-Xiu Bi

Article Number: 468 Published online on: 08 March 2021
Article Open Access

Identification of miR‑145 as a regulator of the cardiomyocyte inflammatory response and oxidative stress under hyperglycemia

Wan Zheng, Tianfa Li, Junping Wei, Yuanyuan Zhang, Qi Zuo, Yun Lin

Article Number: 467 Published online on: 08 March 2021
Article Open Access

Regulatory effect of mitoQ on the mtROS‑NLRP3 inflammasome pathway in leptin‑pretreated BEAS‑2 cells

Lei Chong, Haiyan Li, Lili Zhu, Gang Yu

Article Number: 466 Published online on: 08 March 2021
Article Open Access

Fibrinogen‑to‑albumin ratio predicts long‑term outcomes for patients with ST‑elevation myocardial infarction and multivessel disease: A prospective observational cohort study

Gao Liu, Chuan-Min Fan, Hao Guo, Wei-Na Fan, Ming-Liang Li, Guo-Xiong Cui

Article Number: 465 Published online on: 08 March 2021
Review Open Access

Drug‑coated balloons in the treatment of acute myocardial infarction (Review)

Huilin Hu, Liang Shen

Article Number: 464 Published online on: 05 March 2021
Article

BRAP2 inhibits the Ras/Raf/MEK and PI3K/Akt pathways in leukemia cells, thereby inducing apoptosis and inhibiting cell growth

Hiroharu Sakai, Isamu Shiina, Takahisa Shinomiya, Yukitoshi Nagahara

Article Number: 463 Published online on: 05 March 2021
Article

Graphene oxide induces dose‑dependent lung injury in rats by regulating autophagy

Lei Zhang, Shuge Ouyang, Hongbo Zhang, Mingke Qiu, Yuxin Dai, Shuqing Wang, Yang Wang, Jingmin Ou

Article Number: 462 Published online on: 05 March 2021
Article Open Access

Glycyrrhizic acid restrains airway inflammation and remodeling in asthma via the TGF‑β1/Smad signaling pathway

Ziping Yao, Yanling Fu

Article Number: 461 Published online on: 03 March 2021
Article Open Access

4‑phenylbutyric acid mediates therapeutic effect in systemic lupus erythematosus: Observations in an experimental murine lupus model

Yunjung Choi, Ji-Hyun Jung, Eun-Gyeong Lee, Kyoung Min Kim, Wan-Hee Yoo

Article Number: 460 Published online on: 03 March 2021
Article Open Access

microRNA‑23 inhibits inflammation to alleviate rheumatoid arthritis via regulating CXCL12

Bo Gao, Guomin Sun, Yan Wang, Yaqin Geng, Lei Zhou, Xi Chen

Article Number: 459 Published online on: 03 March 2021
Article Open Access

Correlation between serum 25‑(OH)D3 level and immune imbalance of Th1/Th2 cytokines in patients with Hashimoto's thyroiditis and its effect on autophagy of human Hashimoto thyroid cells

Jing He, Yuanchun Li, Hui Li, Chunhui Zhang, Jian  Zhang, Xiaozhu Sun, Shumei Zheng

Article Number: 458 Published online on: 02 March 2021
Article Open Access

Clinical diagnostic value of combined detection of IMA, D‑D and MCP‑1 in acute myocardial infarction

Mei Ding, Min Li, Hailing Yang

Article Number: 457 Published online on: 02 March 2021
Case Report

Congenital dyserythropoietic anemia and drug‑induced liver injury present as bland cholestasis: A case report

Yue Han, Yan Zhuang, Weiliang Tang, Lu Chen, Yejing Chen, Qiming Gong, Xinxin Zhang

Article Number: 456 Published online on: 02 March 2021
Article

Knockdown of long non‑coding RNA KCNQ1OT1 suppresses the progression of osteoarthritis by mediating the miR‑211‑5p/TCF4 axis in vitro

Dilihumaer Aili, Tong Wu, Yuan Gu, Ziyuan Chen, Wanchun Wang

Article Number: 455 Published online on: 01 March 2021
Article Open Access

Actin-binding protein anillin promotes the progression of hepatocellular carcinoma in vitro and in mice Retraction in /10.3892/etm.2023.12120

Huanxia Jia, Zhenya Gao, Fang Yu, Hongfang Guo, Baoyu Li

Article Number: 454 Published online on: 01 March 2021
Article Open Access

Hydrogen gas alleviates acute alcohol‑induced liver injury by inhibiting JNK activation

Yaxing Zhang, Mingmin Bi, Zifeng Chen, Min Dai, Ge  Zhou, Yuxuan Hu, Hongzhi Yang, Weibing Guan

Article Number: 453 Published online on: 01 March 2021
Article Open Access

Adipose‑derived stem cell sheets combined with β‑tricalcium phosphate/collagen‑I fiber scaffold improve cell osteogenesis

Yang Wang, Xiaojia Song, Rui Lei, Ning Zhang, Liangping Zhang, Wei Xiao, Jinghong Xu, Jun Lin

Article Number: 452 Published online on: 01 March 2021
Article

Protective effects of peptide FK18 against neuro‑excitotoxicity in SH‑SY5Y cells

Shuyu Xiong, Mingming Ma, Yupeng Xu, Fang Wei, Qing Gu, Xiangui He, Xun Xu

Article Number: 451 Published online on: 01 March 2021
Article Open Access

Role of the long non‑coding RNA HOTAIR/miR‑126 axis in an in vitro psoriasis model

Weifeng Zha, Bo Guo, Shuyue Chen, Junwei Lu, Yunyun Shan

Article Number: 450 Published online on: 01 March 2021
Article Open Access

Meta‑analysis of laboratory results in patients with severe coronavirus disease 2019

Yun Huang, Yuyu Zhang, Lili Ma

Article Number: 449 Published online on: 01 March 2021
Article Open Access

Magnolol may contribute to barrier function improvement on imiquimod‑induced psoriasis‑like dermatitis animal model via the downregulation of interleukin‑23

Jiun-Wen Guo, Yu-Pin Cheng, Chih-Yi Liu, Haw-Yueh Thong, Yang Lo, Chen-Yu Wu, Shiou-Hwa Jee

Article Number: 448 Published online on: 01 March 2021
Review Open Access

Recent advances of glucocorticoids in the treatment of Duchenne muscular dystrophy (Review)

Tianyuan Zhang, Xiangdong Kong

Article Number: 447 Published online on: 01 March 2021
Article Open Access
Article

miR‑584 and miR‑146 are candidate biomarkers for acute respiratory distress syndrome

Siquan Zhang, Yinuo Hong, Huafeng Liu, Qianpeng Wang, Juan Xu, Yujuan Zhang, Xi Zhao, Yan Yao, Kexing Zhou, Xianfeng Ding

Article Number: 445 Published online on: 01 March 2021
Article Open Access

Expression of histone deacetylase 2 in tracheal stenosis models and its relationship with tracheal granulation tissue proliferation

Zhenjie Huang, Peng Wei, Luoman Gan, Wentao Li, Tonghua Zeng, Caicheng Qin, Zhiyu Chen, Guangnan Liu

Article Number: 444 Published online on: 01 March 2021
Article Open Access

Oleanolic acid inhibits osteosarcoma cell proliferation and invasion by suppressing the SOX9/Wnt1 signaling pathway

Xianming Chen, Yulin Zhang, Sen Zhang, Aiming Wang, Quanyin Du, Ziming Wang

Article Number: 443 Published online on: 28 February 2021
Article

Clinical application of liver stiffness measurement in patients with cavernous transformation of portal vein

Yue Shen, Wei Ma, Ying Hang, Li-Li Liu, Wei Jiang, Sheng-Di Wu

Article Number: 442 Published online on: 28 February 2021
Article Open Access

Acidic preconditioning reduces lipopolysaccharide‑induced acute lung injury by upregulating the expression of angiotensin‑converting enzyme 2

Guiyuan Yu, Yan Jiao, Jia-Jia Huang, Ming-Da Fan, Yu-Chen Hao, Ji-Zhong Han, Liangchao Qu

Article Number: 441 Published online on: 28 February 2021
Article Open Access

Resveratrol protects against high glucose‑induced oxidative damage in human lens epithelial cells by activating autophagy

Pengzhi Chen, Zhenyu Yao, Zhihui He

Article Number: 440 Published online on: 26 February 2021
Article Open Access

MicroRNA-383 promotes reactive oxygen species-induced autophagy via downregulating peroxiredoxin 3 in human glioma U87 cells

Zhou Xu, Xingruo Zeng, Mingchang Li, Jianming Liao, Qianxue Chen

Article Number: 439 Published online on: 26 February 2021
Article

Laminar shear stress upregulates the expression of PPARs in vascular endothelial cells under high free fatty acid‑induced stress

Yu-Lin Wang, Chen-Te Chen, Che-Se Tung, Min-Chien Tsai

Article Number: 438 Published online on: 26 February 2021
Article Open Access

EZH2 inhibitor GSK343 inhibits sepsis‑induced intestinal disorders

Dongyou Yue, Zhiying Wang, Yongan Yang, Zhenjun Hu, Ganping Luo, Fu Wang

Article Number: 437 Published online on: 26 February 2021
Article Open Access

miR‑23a‑3p regulates the proliferation and apoptosis of human lens epithelial cells by targeting Bcl‑2 in an in vitro model of cataracts

Pengxiang Yao, Jian Jiang, Xiaoping Ma, Zhenzhong Chen, Yufang Hong, Yang Wu

Article Number: 436 Published online on: 26 February 2021
Article Open Access

Effect of TNF‑α on the proliferation and osteogenesis of human periodontal mesenchymal stem cells

Yiting Cao, Yiwei Wang, Chenlin Li, Qian Jiang, Laikuan Zhu

Article Number: 434 Published online on: 26 February 2021
Article Open Access

Estrogen administration attenuates post‑stroke depression by enhancing CREB/BDNF/TrkB signaling in the rat hippocampus

Huigang Jiang, Li Xiao, Kunlin Jin, Bei Shao

Article Number: 433 Published online on: 26 February 2021
Article

Remote ischemic preconditioning does not induce activation of Akt and STAT5 in the rat heart

Annika Raupach, Katharina Feige, Christian Reiter, Timo Brandenburger, Nicole Heinen, André Heinen, Markus W. Hollmann, Ragnar Huhn, Carolin Torregroza

Article Number: 432 Published online on: 26 February 2021
Article Open Access

miR‑135a‑5p inhibitor protects glial cells against apoptosis via targeting SIRT1 in epilepsy

Ying Wang, Zhiquan Yang, Kai Zhang, Yi Wan, Yu Zhou, Zhuanyi Yang

Article Number: 431 Published online on: 26 February 2021
Article Open Access

Dynamic study into autophagy and apoptosis during orthodontic tooth movement

Maoying Wang, Li Zhang, Fuwei Lin, Qian Zheng, Xiaomei Xu, Li Mei

Article Number: 430 Published online on: 26 February 2021
Article Open Access

Anti‑inflammatory effects of Fritillaria thunbergii Miquel extracts in LPS‑stimulated murine macrophage RAW 264.7 cells

Jae-Hyun Kim, Minsun Kim, Sooyeon Hong, Boguen Kwon, Min Wook Song, Kwangchan Song, Eun-Young Kim, Hyuk-Sang Jung, Youngjoo Sohn

Article Number: 429 Published online on: 26 February 2021
Article Open Access

Huanglian‑Houpo drug combination ameliorates H1N1‑induced mouse pneumonia via cytokines, antioxidant factors and TLR/MyD88/NF‑κB signaling pathways

Li Zhang, Bei Zhang, Linjing Wang, Mingwu Lou, Yunxia Shen

Article Number: 428 Published online on: 26 February 2021
Article Open Access

Protective effects of dexmedetomidine on the ischemic myocardium in patients undergoing rheumatic heart valve replacement surgery

Wei Chen, Yan Wang, Zhiguo Pan, Xiyuan Chen, Dihuan Luo, Haiying Wang

Article Number: 427 Published online on: 26 February 2021
Article Open Access

Chlorogenic acid enhances autophagy by upregulating lysosomal function to protect against SH‑SY5Y cell injury induced by H2O2

Li-Juan Gao, Yuan Dai, Xiao-Qiong Li, Shi Meng, Zhan-Qiong Zhong, Shi-Jun Xu

Article Number: 426 Published online on: 26 February 2021
Article Open Access

Kuwanon G protects HT22 cells from advanced glycation end product-induced damage

Wen-Jun Gan, Chen-Lin Gao, Wen-Qian Zhang, Jun-Ling Gu, Ting-Ting Zhao, Heng-Li Guo, Hua Zhou, Yong Xu, Li-Li Yu, Li-Fang Li, Ding-Kun Gui, You-Hua Xu

Article Number: 425 Published online on: 25 February 2021
Article Open Access

Lidocaine suppresses the malignant behavior of gastric cancer cells via the c‑Met/c‑Src pathway

Wei Zeng, Ze Ting Xing, Mei Yun Tan, Yan Wen Wu, Chun Yuan Zhang

Article Number: 424 Published online on: 25 February 2021
Review

Role of HDAC6 inhibition in sepsis‑induced acute respiratory distress syndrome (Review)

Qinghua Zhang, Yan Wang, Danhua Qu, Jinyan Yu, Junling Yang

Article Number: 422 Published online on: 25 February 2021
Article Open Access

Effects of norepinephrine on colonic tight junction protein expression during heat stress

Yan Luo, Huiming Ma, Shibo Niu, Xu Li, Lihong Nie, Guanghua Li

Article Number: 421 Published online on: 25 February 2021
Article

Emodin induces collagen type I synthesis in Hs27 human dermal fibroblasts

Parkyong Song, Han-Seul Jo, Wan-Seog Shim, Yang Woo Kwon, Sungwon Bae, Yonghoon Kwon, Bakhovuddin Azamov, Jin Hur, Dongjun Lee, Sung Ho Ryu, Jong Hyuk Yoon

Article Number: 420 Published online on: 25 February 2021
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Radioprotective effects of centipedegrass extract on NIH‑3T3 fibroblasts via anti‑oxidative activity

Seong Hee Kang, Dong-Ho Bak, Seung Sik Lee, Hyoung-Woo Bai, Byung Yeoup Chung, Bo Sun Kang

Article Number: 419 Published online on: 25 February 2021
Article Open Access

Distinctive gut microbial dysbiosis between chronic alcoholic fatty liver disease and metabolic‑associated fatty liver disease in mice

Kai Kang, Yue Sun, Dan Pan, Li-Xuan Sang, Ming-Jun Sun, Yi-Ling Li, Bing Chang

Article Number: 418 Published online on: 25 February 2021
Article

Hyperresponsiveness of human gingival fibroblasts from patients with aggressive periodontitis against bacterial lipopolysaccharide

Xue Li, Xiaoxuan Wang, Qing-Xian Luan

Article Number: 417 Published online on: 25 February 2021
Article Open Access

Mutational landscape and potential therapeutic targets for sporadic pancreatic neuroendocrine tumors based on target next‑generation sequencing

Kailian Zheng, Tao Liu, Jiangman Zhao, Peng Meng, Yun Bian, Chenming Ni, Huan Wang, Yaqi Pan, Shouxin Wu, Hui Jiang, Gang Jin

Article Number: 415 Published online on: 25 February 2021
Article Open Access

miR‑130a‑3p promotes cell proliferation and invasion by targeting estrogen receptor α and androgen receptor in cervical cancer

Qiong Fan, Ting Huang, Xiao Sun, Xiaoming Yang, Jing Wang, Yao Liu, Ting Ni, Shenglan Gu, Yuhong Li, Yudong Wang

Article Number: 414 Published online on: 25 February 2021
Article Open Access

Underlying mechanisms of the effect of minocycline against Candida albicans biofilms

Li Zou, Zhao Mei, Tao Guan, Bo Zhang, Qun Deng

Article Number: 413 Published online on: 25 February 2021
Article Open Access
Journal Cover

May-2021
Volume 21 Issue 5

Print ISSN: 1792-0981
Online ISSN: 1792-1015

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