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Diagnosis of adult‑onset MELAS with suspected recurrent strokes: A case report

  • Authors:
    • Fei Yang
    • Shan Peng
    • Qiaojun Peng
  • View Affiliations / Copyright

    Affiliations: Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China, Department of Medical Rehabilitation, The Second Clinical College of North Sichuan Medical College, Nanchong Central Hospital, Nanchong, Sichuan 637000, P.R. China
    Copyright: © Yang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 466
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    Published online on: May 25, 2022
       https://doi.org/10.3892/etm.2022.11393
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Abstract

Mitochondrial encephalomyopathy, lactic acidosis and stroke‑like episodes (MELAS) is caused by mutations in mitochondrial DNA and is one of the most common syndromes among the mitochondrial diseases. Clinical manifestations typically occur before the age of 40 years. The present study reports a case of MELAS with a mutation in the adenine to guanine conversion at mitochondrial genome 3243 in a 48‑year‑old woman who was suspected of suffering from recurrent strokes. Finally, the genomic analysis confirmed the diagnosis of MELAS. This case highlights the importance of considering MELAS as a potential cause of recurrent stroke‑like events if imaging findings are atypical for cerebral infarction, even among middle‑aged patients with vascular risk factors.
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Copy and paste a formatted citation
Spandidos Publications style
Yang F, Peng S and Peng Q: Diagnosis of adult‑onset MELAS with suspected recurrent strokes: A case report. Exp Ther Med 24: 466, 2022.
APA
Yang, F., Peng, S., & Peng, Q. (2022). Diagnosis of adult‑onset MELAS with suspected recurrent strokes: A case report. Experimental and Therapeutic Medicine, 24, 466. https://doi.org/10.3892/etm.2022.11393
MLA
Yang, F., Peng, S., Peng, Q."Diagnosis of adult‑onset MELAS with suspected recurrent strokes: A case report". Experimental and Therapeutic Medicine 24.1 (2022): 466.
Chicago
Yang, F., Peng, S., Peng, Q."Diagnosis of adult‑onset MELAS with suspected recurrent strokes: A case report". Experimental and Therapeutic Medicine 24, no. 1 (2022): 466. https://doi.org/10.3892/etm.2022.11393
Copy and paste a formatted citation
x
Spandidos Publications style
Yang F, Peng S and Peng Q: Diagnosis of adult‑onset MELAS with suspected recurrent strokes: A case report. Exp Ther Med 24: 466, 2022.
APA
Yang, F., Peng, S., & Peng, Q. (2022). Diagnosis of adult‑onset MELAS with suspected recurrent strokes: A case report. Experimental and Therapeutic Medicine, 24, 466. https://doi.org/10.3892/etm.2022.11393
MLA
Yang, F., Peng, S., Peng, Q."Diagnosis of adult‑onset MELAS with suspected recurrent strokes: A case report". Experimental and Therapeutic Medicine 24.1 (2022): 466.
Chicago
Yang, F., Peng, S., Peng, Q."Diagnosis of adult‑onset MELAS with suspected recurrent strokes: A case report". Experimental and Therapeutic Medicine 24, no. 1 (2022): 466. https://doi.org/10.3892/etm.2022.11393
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