Myasthenia gravis that has developed long after radical resection of lung cancer: A case report

  • Authors:
    • Shinichiro Okauchi
    • Ayako Shioya
    • Kesato Iguchi
    • Kinya Furukawa
    • Hiroaki Satoh
  • View Affiliations

  • Published online on: July 5, 2022     https://doi.org/10.3892/etm.2022.11492
  • Article Number: 554
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Myasthenia gravis (MG) is the most common disorder of neuromuscular transmission and is a heterogeneous disorder generally caused by auto‑antibody to the nicotinic acetylcholine receptor. The current study presented a rare case of MG that occurred a long time after surgical resection of lung cancer. A 58‑year‑old man with lung adenocarcinoma underwent upper lobectomy and mediastinal lymph node dissection. Severe myasthenic symptoms began 7 years after the operation, and emergent mechanical ventilation was needed because of myasthenic crises. Levels of serum anti‑acetylcholine receptor antibody were high and typical decremental responses to repetitive stimulation on electromyography were observed. Appropriate therapies for a severe acute condition were performed, and MG has been controlled for 6 years since then. There is no recurrence of lung cancer or appearance of thymoma. In conclusion, although very rare, physicians should be aware of MG as a potential comorbidity developing in patients with a history of lung cancer.

Related Articles

Journal Cover

September-2022
Volume 24 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Okauchi S, Shioya A, Iguchi K, Furukawa K and Satoh H: Myasthenia gravis that has developed long after radical resection of lung cancer: A case report. Exp Ther Med 24: 554, 2022
APA
Okauchi, S., Shioya, A., Iguchi, K., Furukawa, K., & Satoh, H. (2022). Myasthenia gravis that has developed long after radical resection of lung cancer: A case report. Experimental and Therapeutic Medicine, 24, 554. https://doi.org/10.3892/etm.2022.11492
MLA
Okauchi, S., Shioya, A., Iguchi, K., Furukawa, K., Satoh, H."Myasthenia gravis that has developed long after radical resection of lung cancer: A case report". Experimental and Therapeutic Medicine 24.3 (2022): 554.
Chicago
Okauchi, S., Shioya, A., Iguchi, K., Furukawa, K., Satoh, H."Myasthenia gravis that has developed long after radical resection of lung cancer: A case report". Experimental and Therapeutic Medicine 24, no. 3 (2022): 554. https://doi.org/10.3892/etm.2022.11492