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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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September-2022 Volume 24 Issue 3

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Case Report

Myasthenia gravis that has developed long after radical resection of lung cancer: A case report

  • Authors:
    • Shinichiro Okauchi
    • Ayako Shioya
    • Kesato Iguchi
    • Kinya Furukawa
    • Hiroaki Satoh
  • View Affiliations / Copyright

    Affiliations: Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 3100015, Japan, Division of Neurology, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 3100015, Japan, Division of Thoracic Surgery, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 3100015, Japan, Division of Thoracic Surgery, Ibaraki Medical Center, Tokyo Medical University, Ami, Ibaraki 3000395, Japan, Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 3100015, Japan
  • Article Number: 554
    |
    Published online on: July 5, 2022
       https://doi.org/10.3892/etm.2022.11492
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Abstract

Myasthenia gravis (MG) is the most common disorder of neuromuscular transmission and is a heterogeneous disorder generally caused by auto‑antibody to the nicotinic acetylcholine receptor. The current study presented a rare case of MG that occurred a long time after surgical resection of lung cancer. A 58‑year‑old man with lung adenocarcinoma underwent upper lobectomy and mediastinal lymph node dissection. Severe myasthenic symptoms began 7 years after the operation, and emergent mechanical ventilation was needed because of myasthenic crises. Levels of serum anti‑acetylcholine receptor antibody were high and typical decremental responses to repetitive stimulation on electromyography were observed. Appropriate therapies for a severe acute condition were performed, and MG has been controlled for 6 years since then. There is no recurrence of lung cancer or appearance of thymoma. In conclusion, although very rare, physicians should be aware of MG as a potential comorbidity developing in patients with a history of lung cancer.
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Copy and paste a formatted citation
Spandidos Publications style
Okauchi S, Shioya A, Iguchi K, Furukawa K and Satoh H: Myasthenia gravis that has developed long after radical resection of lung cancer: A case report. Exp Ther Med 24: 554, 2022.
APA
Okauchi, S., Shioya, A., Iguchi, K., Furukawa, K., & Satoh, H. (2022). Myasthenia gravis that has developed long after radical resection of lung cancer: A case report. Experimental and Therapeutic Medicine, 24, 554. https://doi.org/10.3892/etm.2022.11492
MLA
Okauchi, S., Shioya, A., Iguchi, K., Furukawa, K., Satoh, H."Myasthenia gravis that has developed long after radical resection of lung cancer: A case report". Experimental and Therapeutic Medicine 24.3 (2022): 554.
Chicago
Okauchi, S., Shioya, A., Iguchi, K., Furukawa, K., Satoh, H."Myasthenia gravis that has developed long after radical resection of lung cancer: A case report". Experimental and Therapeutic Medicine 24, no. 3 (2022): 554. https://doi.org/10.3892/etm.2022.11492
Copy and paste a formatted citation
x
Spandidos Publications style
Okauchi S, Shioya A, Iguchi K, Furukawa K and Satoh H: Myasthenia gravis that has developed long after radical resection of lung cancer: A case report. Exp Ther Med 24: 554, 2022.
APA
Okauchi, S., Shioya, A., Iguchi, K., Furukawa, K., & Satoh, H. (2022). Myasthenia gravis that has developed long after radical resection of lung cancer: A case report. Experimental and Therapeutic Medicine, 24, 554. https://doi.org/10.3892/etm.2022.11492
MLA
Okauchi, S., Shioya, A., Iguchi, K., Furukawa, K., Satoh, H."Myasthenia gravis that has developed long after radical resection of lung cancer: A case report". Experimental and Therapeutic Medicine 24.3 (2022): 554.
Chicago
Okauchi, S., Shioya, A., Iguchi, K., Furukawa, K., Satoh, H."Myasthenia gravis that has developed long after radical resection of lung cancer: A case report". Experimental and Therapeutic Medicine 24, no. 3 (2022): 554. https://doi.org/10.3892/etm.2022.11492
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