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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2022 Volume 24 Issue 3

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Impact Factor: 2.3

Review Open Access

Understanding the mechanisms of gallbladder lesions: A systematic review

Andrei Bojan, Liliana Georgeta Foia, Maria Cristina Vladeanu, Iris Bararu Bojan, Carmen Plesoianu, Alexandru Plesoianu, Catalin Pricop
Article Number: 604
Published online on: 29 July 2022

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Article Open Access

ROCK2 knockdown alleviates LPS‑induced inflammatory injury and apoptosis of renal tubular epithelial cells via the NF‑κB/NLRP3 signaling pathway

Xinfeng Qian, Linjun Yang
Article Number: 603
Published online on: 28 July 2022

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Review Open Access

Emerging roles of oxidative stress in the pathogenesis of pseudoexfoliation syndrome (Review)

Stylianos Mastronikolis, Marina Pagkalou, Panagiotis Plotas, Konstantinos Kagkelaris, Constantinos D. Georgakopoulos
Article Number: 602
Published online on: 28 July 2022

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Article Open Access

Inhibition of NLRC5 attenuates the malignant growth and enhances the sensitivity of gastric cancer cells to 5‑FU chemotherapy by blocking the carcinogenic effect of YY1

Shan Liang, Tingting Xiang, Shiyu Liu, Wei Xiang
Article Number: 601
Published online on: 28 July 2022

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Case Report Open Access

Novel SPTB frameshift mutation in a Chinese neonatal case of hereditary spherocytosis type 2: A case report

Cunxin Xu, Ya Wu, Dujuan Wang, Xuemin Zhang, Ningling Wang
Article Number: 600
Published online on: 28 July 2022

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Article Open Access

Regulation of the TUG1/miR‑145‑5p/SOX2 axis on the migratory and invasive capabilities of melanoma cells

Jiabin Deng, Yinqiu Li, Jiaqian Song, Fei Zhu
Article Number: 599
Published online on: 28 July 2022

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Article Open Access

A potential link between plasma short‑chain fatty acids, TNF‑α level and disease progression in non‑alcoholic fatty liver disease: A retrospective study

Jing Xiong, Xia Chen, Zhijing Zhao, Ying Liao, Ting Zhou, Qian Xiang
Article Number: 598
Published online on: 28 July 2022

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Case Report Open Access

A patient with pseudohypoparathyroidism type 1A previously misdiagnosed as hereditary multiple exostosis: A case report

Jie Zhang, Ming Guan, Shiyong Zhao, Suling Wu, Lingwei Weng, Wenbin Sheng
Article Number: 597
Published online on: 28 July 2022

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Article Open Access

Curcumin activates autophagy and attenuates high glucose‑induced apoptosis in HUVECs through the ROS/NF‑κB signaling pathway

Qi-Hui Jin, Xu-Jun Hu, Hai-Yan Zhao
Article Number: 596
Published online on: 28 July 2022

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Article Open Access

Decreased low‑density lipoprotein and the presence of pulmonary arterial hypertension among newly diagnosed drug‑naïve patients with systemic lupus erythematosus: D‑dimer as a mediator

Jing Huang, Qi An, Cai-Lian Zhang, Lan He, Lei Wang
Article Number: 595
Published online on: 27 July 2022

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Case Report Open Access

Pulmonary adenofibroma with central liquefaction necrosis: A case report

Ruxin Shen, Lili She, Zhaoshui Li
Article Number: 594
Published online on: 27 July 2022

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Case Report Open Access

Multiple benign fibrous histiocytomas of the mandible: A case report and review of the literature

Yue Wang, Yun Huang, Wei-Xin Cai, Qian Tao
Article Number: 593
Published online on: 27 July 2022

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Article Open Access

Radial head arthroplasty vs. open reduction and internal fixation for the treatment of terrible triad injury of the elbow: A systematic review and meta‑analysis update

Xi-Yong Li, Yun-Lu Wang, Su Yang, Peng-Fei Han
Article Number: 592
Published online on: 27 July 2022

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Article Open Access

Role of glutathione‑S‑transferase gene P1 in the diagnosis of prostate cancer in patients with ‘grey level’ prostate‑specific antigen values

Marius Stan, Vladimir Botnarciuc, Andra-Iulia Suceveanu, Laura Mazilu, Daniel Ovidiu Costea, Adrian-Paul Suceveanu, Dragos Serban, Corneliu Tudor, Anca Mitroi, Costel Brinzan, Felix Voinea
Article Number: 591
Published online on: 26 July 2022

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Article

Suppression of xenogeneic innate immune response by a membrane‑type human surfactant protein‑A

Chiyoshi Toyama, Akira Maeda, Shuhei Kogata, Riho Yamamoto, Kazunori Masahata, Takehisa Ueno, Masafumi Kamiyama, Yuko Tazuke, Hiroshi Eguchi, Hiroomi Okuyama, Shuji Miyagawa
Article Number: 590
Published online on: 26 July 2022

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Article Open Access

Protective effects of budesonide on LPS‑induced podocyte injury by modulating macrophage M1/M2 polarization: Evidence from in vitro and in silico studies

Xilan Zhang, Guangying Wang, Dayue Shen, Yating Feng, Yan Zhang, Chao Zhang, Yuanping Li, Hui Liao
Article Number: 589
Published online on: 26 July 2022

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Case Report

Spontaneous renal rupture due to renal calculi: A case report and literature review

Guicao Yin, Xiang Pan, Haoyu Tian, Zhengxi Zhou, Junhui Li, Feng Tian, Qibing Fan, Xiaoxiang Wang, Lezhong Qi, Yifan Li
Article Number: 588
Published online on: 26 July 2022

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Article Open Access

Adipose‑derived stem cells postpone the progression of Sjögren's syndrome by upregulating the Hippo signaling pathway

Zizhan Li, Xinli Fan, Xiuying Xu, Qin Zhou, Guimiao Xing, Gangli Liu
Article Number: 587
Published online on: 22 July 2022

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Article Open Access

Resveratrol ameliorates oxaliplatin‑induced neuropathic pain via anti‑inflammatory effects in rats

Zhi-Bin Dong, Yu-Jia Wang, Wen-Jun Wan, Ji Wu, Bo-Jun Wang, Hai-Li Zhu, Min Xie, Ling Liu
Article Number: 586
Published online on: 21 July 2022

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Article Open Access

HOXB5‑activated ANGPT2 promotes the proliferation, migration, invasion and angiogenic effect of esophageal cancer cells via activating ERK/AKT signaling pathway

Jing Li, Shanshan Gao
Article Number: 585
Published online on: 20 July 2022

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Article Open Access

Association of vitamin D receptor gene haplotypes with late‑onset Alzheimer's disease in a Southeastern European Caucasian population

Efthimios Dimitrakis, Martha-Spyridoula Katsarou, Maria Lagiou, Vasiliki Papastefanopoulou, Demetrios A. Spandidos, Aristidis Tsatsakis, Socratis Papageorgiou, Paraskevi Moutsatsou, Katerina Antoniou, Christos Kroupis, Nikolaos Drakoulis
Article Number: 584
Published online on: 19 July 2022

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Article Open Access

Management of a rare ovarian carcinosarcoma: A case report and literature review

Jun Fu
Article Number: 583
Published online on: 19 July 2022

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Review Open Access

Exosomes and exosomal non‑coding RNAs throughout human gestation (Review)

Ioanna Maligianni, Christos Yapijakis, Konstantina Nousia, Flora Bacopoulou, George P. Chrousos
Article Number: 582
Published online on: 19 July 2022

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Article Open Access

Laparoscopic surgery of intra‑abdominal lymphatic malformation in children

Qianlong Liu, Jialu Fu, Qiang Yu, Wei Gong, Peng Li, Xinkui Guo
Article Number: 581
Published online on: 19 July 2022

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Case Report Open Access

Immune thrombocytopenic purpura induced by the COVID‑19 vaccine after the second dose in a 78‑year‑old patient: A case report

Wenhui Liu, Tao Wu, Feng Xue, Hongjuan Tian, Rui Song, Hai Bai
Article Number: 580
Published online on: 19 July 2022

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Article Open Access

Role and mechanism of the zinc finger protein ZNF580 in foam‑cell formation

Zhongbai Zhang, Xueting Qin, Jiyuan Liu, Yanchun Li, Huaxin Chen, Hongwei Xie, Jingxun Chen, Chuang Li, Yang Tong, Min Yang, Mei Zhang
Article Number: 579
Published online on: 19 July 2022

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Article Open Access

Combination of azithromycin and methylprednisolone alleviates Mycoplasma pneumoniae induced pneumonia by regulating miR‑499a‑5p/STAT3 axis

Yongli Chen, Shanwu Dong, Lin Tian, Haishan Chen, Jing Chen, Chunzhi He
Article Number: 578
Published online on: 19 July 2022

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Article

Tiotropium as an add‑on treatment to inhaled corticosteroids in children with severe and mild symptomatic asthma: Multi‑center observational study for efficacy and safety analysis

Aibibai Aierken, Bu Wei Mai Erye Mu Yu Su Fu, Peiru Xu
Article Number: 577
Published online on: 19 July 2022

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Article Open Access

IL‑6 inhibitors effectively reverse post‑infarction cardiac injury and ischemic myocardial remodeling via the TGF‑β1/Smad3 signaling pathway

Jiahong Wang, Minghong Wang, Xiancheng Lu, Yi Zhang, Siliang Zeng, Xin Pan, Yimeng Zhou, Hui Wang, Nannan Chen, Fengfeng Cai, Ewelina Biskup
Article Number: 576
Published online on: 18 July 2022

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Article Open Access

Comparison of a histone deacetylase inhibitor plus exemestane with exemestane alone in hormone receptor‑positive advanced breast cancer that progressed on prior endocrine therapy: A meta‑analysis

Liang Xu, Weifan Jiang, Wenwei Li, Chungen Guo, Lihua Luo, Yufeng Gao, Yali Cao
Article Number: 575
Published online on: 18 July 2022

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Case Report Open Access

Central precocious puberty occurring in Bardet‑Biedl syndrome‑10 as a method for self‑protection of human reproductive function: A case report

Hanming Li, Jianyu He, Iatlun Leong, Runxiao Huang, Xiaojie Shi
Article Number: 574
Published online on: 15 July 2022

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Case Report Open Access

Early detection of gram‑negative bacteria using metagenomic next‑generation sequencing in acute respiratory distress syndrome: A case report

Rong Wang, Rong Feng, Chaoran Xia, Fangying Ruan, Peng Luo, Jun Guo
Article Number: 573
Published online on: 15 July 2022

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Article Open Access

Transmembrane protein 121 as a novel inhibitor of cervical cancer metastasis

Boyu Yang, Yi Cai, Ping Zhu, Zhigang Jiang, Jieyu Ao, Qing Zhang, Wuzhou Yuan, Zhilin Peng, Jimei Chen, Yao Wen, Yu Chen, Yuequn Wang, Yan Shi, Xiaolan Zhu, Xiangli Ye, Fang Li, Jian Zhuang, Xiushan Wu, Yongqing Li, Xiongwei Fan
Article Number: 572
Published online on: 15 July 2022

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Article Open Access

Utility of routine laboratory tests in the assessment of chronic venous disease progression in female patients

Sergiu-Ciprian Matei, Mervat Matei, Flavia Medana Anghel, Emma Carabenciov, Marius-Sorin Murariu, Sorin Olariu
Article Number: 571
Published online on: 14 July 2022

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Article Open Access

Combination of Sophora flavescens alkaloids and Panax quinquefolium saponins modulates different stages of experimental autoimmune myocarditis via the NF‑κB and TGF‑β1 pathways

Menghui Liu, Yue Lin, Huibo Xu, Lixin Li, Tao Ding
Article Number: 570
Published online on: 14 July 2022

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Review

Pathophysiology of cognitive dysfunction and the role of combined brain/heart magnetic resonance imaging (Review)

George Markousis‑Mavrogenis, Flora Bacopoulou, Genovefa Kolovou, Maria-Roser Pons, Aikaterini Giannakopoulou, Antigoni Papavasiliou, George D. Kitas, George P. Chrousos, Sophie I. Mavrogeni
Article Number: 569
Published online on: 14 July 2022

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Article Open Access

PAD4 silencing inhibits inflammation whilst promoting trophoblast cell invasion and migration by inactivating the NEMO/NF‑κB pathway

Min Zeng, Minjuan Xu, Xiafang Li, Junying Li, Yuanyuan Liu
Article Number: 568
Published online on: 12 July 2022

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Article Open Access

Interleukin 32 participates in cardiomyocyte‑induced oxidative stress, inflammation and apoptosis during hypoxia/reoxygenation via the NOD2/NOX2/MAPK signaling pathway

Yuanyuan Li, Zhongyan Wang
Article Number: 567
Published online on: 12 July 2022

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Article Open Access

The role of human antigen R (HuR) in modulating proliferation, senescence and radiosensitivity of skin cells

Daojiang Yu, Yahui Feng, Zhiqiang Jiang, Tao Yan, Kai Fang, Yuhong Shi, Jie Zhang, Shuyu Zhang
Article Number: 566
Published online on: 12 July 2022

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Article Open Access

X‑linked adrenoleukodystrophy caused by maternal ABCD1 mutation and paternal X chromosome inactivation

Zhen Li, Guangrui Lai
Article Number: 565
Published online on: 12 July 2022

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Article Open Access

miR‑374a‑5p alleviates sepsis‑induced acute lung injury by targeting ZEB1 via the p38 MAPK pathway

Jia Shen, Xiaojun Ma
Article Number: 564
Published online on: 12 July 2022

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Article Open Access

LTBP2 inhibits prostate cancer progression and metastasis via the PI3K/AKT signaling pathway

Xiaowen Zhang, Chuanjie Tian, Jianbin Cheng, Weipu Mao, Menglan Li, Ming Chen
Article Number: 563
Published online on: 08 July 2022

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Article Open Access

Preventive measures significantly reduced the risk of nosocomial infection in elderly inpatients during the COVID‑19 pandemic

Shuangshuang Wu, Wen Liu, Mingjiong Zhang, Kai Wang, Jin Liu, Yujia Hu, Quan She, Min Li, Shaoran Shen, Bo Chen, Jianqing Wu
Article Number: 562
Published online on: 06 July 2022

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Article Open Access

Bioinformatics analysis of KLF2 as a potential prognostic factor in ccRCC and association with epithelial‑mesenchymal transition

Fangfang Hu, Yan Ren, Zunyun Wang, Hui Zhou, Yumei Luo, Minghua Wang, Faqing Tian, Jian Zheng, Juan Du, Gang Pang
Article Number: 561
Published online on: 05 July 2022

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Article Open Access

Decreased complement 4d increases poor prognosis in patients with non‑small cell lung cancer combined with gastrointestinal lymph node metastasis

Yan Wang, Mengqi Xiang, Huachuan Zhang, Yongda Lu
Article Number: 560
Published online on: 05 July 2022

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Article Open Access

Sternum length norms in Han youngsters in central China

Shuai Li, Ping Lei, Yuan Liu, Cen Chen, Dehua Yang, Xin Li, Shao-Tao Tang
Article Number: 559
Published online on: 05 July 2022

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Article Open Access

A‑kinase interacting protein 1 regulates the cell proliferation, invasion, migration and angiogenesis of clear cell renal cell carcinoma cells and affects the ERK/c‑Myc signaling pathway by binding to Rac1

Yu Zhang, Haijian Zhang, Zhixing Han, Xudong Wang, Xuyu Li, Pengfei Yuan, Shiqi Ji, Qingjun Liu
Article Number: 558
Published online on: 05 July 2022

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Article Open Access

Inflammatory and autoimmune predictive markers of response to anti‑PD‑1/PD‑L1 therapy in NSCLC and melanoma

Aram A. Musaelyan, Sergey V. Lapin, Margarita A. Urtenova, Svetlana V. Odintsova, Ivan V. Chistyakov, Andrey M. Ulitin, Andrey L. Akopov, Sergey V. Orlov
Article Number: 557
Published online on: 05 July 2022

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Case Report Open Access

Moyamoya syndrome with ruptured aneurysm in α‑thalassemia: A case report

Jiabin Zhu, Mingwen Zhang, Yichun Sun, Xiaofeng Zhang
Article Number: 556
Published online on: 05 July 2022

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Article Open Access

An in vitro study on the effect of bevacizumab on endothelial cell proliferation and VEGF concentration level in patients with hereditary hemorrhagic telangiectasia

Haneen Sadick, Elena Schäfer, Christel Weiss, Nicole Rotter, Cornelia Emika Müller, Richard Birk, Maliha Sadick, Daniel Häussler
Article Number: 555
Published online on: 05 July 2022

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Case Report

Myasthenia gravis that has developed long after radical resection of lung cancer: A case report

Shinichiro Okauchi, Ayako Shioya, Kesato Iguchi, Kinya Furukawa, Hiroaki Satoh
Article Number: 554
Published online on: 05 July 2022

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Retraction Open Access

[Retracted] MicroRNA‑548b inhibits proliferation and invasion of hepatocellular carcinoma cells by directly targeting specificity protein 1

Haile Qiu, Gehong Zhang, Bin Song, Junmei Jia
Article Number: 553
Published online on: 04 July 2022

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Article Open Access

Long non‑coding RNA PVT1 regulates LPS‑induced acute kidney injury in an in vitro model of HK‑2 cells by modulating the miR‑27a‑3p/OXSR1 axis

Qian Yang, Qi Sun, Ping Jin
Article Number: 552
Published online on: 01 July 2022

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Article Open Access

FOSL1 knockdown ameliorates DSS‑induced inflammation and barrier damage in ulcerative colitis via MMP13 downregulation

Lizhuan Ma, Xiujing Zhang, Chao Zhang, Bingxu Hou, Hongtao Zhao
Article Number: 551
Published online on: 01 July 2022

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Case Report

Cardiac hydatid cysts in a young man: A case report and a literature review

Mircea Bajdechi, Dalia Manolache, Adrian Tudor, Mihnea Orghidan, Adriana Gurghean
Article Number: 550
Published online on: 01 July 2022

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Article Open Access

Ropivacaine has the potential to relieve PM2.5‑induced acute lung injury

Rui Zuo, Xin-Yu Li, Yong-Guan He
Article Number: 549
Published online on: 01 July 2022

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Review Open Access

Tensioned space after pneumonectomy for cancer with mediastinal shift and cardiac tamponade‑causes and treatment (Review)

Natalia Motas, Veronica Manolache, Ovidiu Rus, Mihnea Davidescu, Madalina Cristiana Cioalca‑iliescu, Bogdan Socea, Mihail Constantin Ceausu, Oana Gabriela Trifanescu
Article Number: 548
Published online on: 01 July 2022

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Review Open Access

Pharmacological profiles and therapeutic applications of pachymic acid (Review)

Chunyong Wei, Hezhen Wang, Xun Sun, Zhixun Bai, Jing Wang, Guohui Bai, Qizheng Yao, Yingshu Xu, Lei Zhang
Article Number: 547
Published online on: 01 July 2022

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Article Open Access

Establishment and verification of potential biomarkers for cholangiocarcinoma

Shuai Wang, Leilei Yu, Xiangyu Sun, Bo Zhang
Article Number: 546
Published online on: 30 June 2022

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Article Open Access

Ginsenoside Rg1 ameliorates apoptosis, senescence and oxidative stress in ox‑LDL‑induced vascular endothelial cells via the AMPK/SIRT3/p53 signaling pathway

Tian-Jiao Lyu, Zi-Xiu Zhang, Jun Chen, Zong-Jun Liu
Article Number: 545
Published online on: 30 June 2022

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Article Open Access

Blood CDC42 overexpression is associated with an increased risk of acute exacerbation, inflammation and disease severity in patients with chronic obstructive pulmonary disease

Xiaoyan Ming, Fan Yang, Hong Zhu
Article Number: 544
Published online on: 30 June 2022

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Article Open Access

Role of PIM2 in acute lung injury induced by sepsis

Juncai Ding, Xiufang Yang, Huijuan Huang, Bo Wang
Article Number: 543
Published online on: 30 June 2022

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Article Open Access

Mutation analysis of circulating tumor DNA and paired ascites and tumor tissues in ovarian cancer

Xiaoxiang Jie, Ming Du, Meng Zhang, Xiayu Jin, Qingqing Cai, Congjian Xu, Xiaoyan Zhang
Article Number: 542
Published online on: 30 June 2022

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Tristetraprolin regulates phagocytosis through interaction with CD47 in head and neck cancer

Won Hyeok Lee, Song Hee Kim, Jae Hee An, Tae-Koon Kim, Hee Jeong Cha, Hyo Won Chang, Sang Yoon Kim, Seong Who Kim, Myung Woul Han
Article Number: 541
Published online on: 29 June 2022

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March-2026 Volume 31 Issue 3

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Impact Factor: 2.3

Article Open Access

Effect of SGLT2 inhibitors on heart failure outcomes in patients with and without diabetes: A systematic review and meta‑analysis of randomized controlled trials

Duaa Abdullah Bafail, Noura Hamdi Alhalees
Article Number: 84
Published online on: 28 January 2026

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Exploring the protective mechanisms and therapeutic potential of carnosic acid against acute respiratory distress syndrome through molecular docking, molecular dynamics and experimental verification

Quan Li, Lili Ding, Haijun Sun, Weichao Ding, Mengmeng Wang, Zhaorui Sun, Congxue Ma
Article Number: 83
Published online on: 28 January 2026

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Review

Exploring the roots of schizophrenia: Current research and future directions (Review)

Shuang Lv, Chunxia Luo
Article Number: 82
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] miR‑146a‑5p protects against renal injury in MRL/lpr mice via improvement of the Treg/Th17 imbalance by targeting the TRAF6/NF‑κB axis

Jiajia Teng, Feng Yang, Xiaoling Li
Article Number: 81
Published online on: 28 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑24‑3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl‑2‑like protein 11

Huanxin Zhang, Shizhen Xue, Yi Feng, Jun Shen, Jixian Zhao
Article Number: 80
Published online on: 26 January 2026

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Efficacy and safety of unilateral biportal endoscopy vs. percutaneous endoscopic interlaminar approach in lumbar disc herniation: A meta‑analysis​

Yuhao Gao, Fangzheng He, Ji Wen, Shilei Qin, Pengfei Han, Yunfeng Xu
Article Number: 79
Published online on: 23 January 2026

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Case Report Open Access

Intralobar pulmonary sequestration coexisting with pulmonary cryptococcosis: A case report and literature review

Dan Cheng, Yue Wang, Jun Li, Dan Yu, Yunyun Wang, Jinbo Fan, Jiankun Wang, Liqun He
Article Number: 78
Published online on: 23 January 2026

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Tumor‑associated macrophages suppress estrogen receptor‑β expression in triple‑negative breast cancer through the PI3K/AKT pathway

Qiulei Zhang, Di Guo, Gaoran Xu, Rong Xie, Yuqing Deng, Peng Fu, Jinnan Wan
Article Number: 77
Published online on: 21 January 2026

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Development of a diagnostic model for esophageal achalasia assessed by esophageal high‑resolution manometry using artificial intelligence

Maiko Tabuchi, Yasuhiko Nakao, Hitomi Minami, Hiroko Inomata, Junya Shiota, Taro Akashi, Keiichi Hashiguchi, Moto Kitayama, Kayoko Matsushima, Naoyuki Yamaguchi, Yuko Akazawa, Hisamitsu Miyaaki
Article Number: 76
Published online on: 21 January 2026

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Case Report

Use of metagenomic next‑generation sequencing to diagnose Tropheryma whipplei infection‑related pneumonia: A case report

Yutu Luo, Haibing Ding, Jiahua Pan, Guangyang Xu
Article Number: 75
Published online on: 21 January 2026

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Effect of rivaroxaban on DNA damage in an ischemia-reperfusion model: Evaluation of 8‑OHdG levels

Ceren Sayarer, Abidin Cenk Erdal, Tuğra Gençpinar, Özlem Gürsoy Doruk, Tuncay Küme
Article Number: 74
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Hepatoprotective activity of chrysin is mediated through TNF‑α in chemically‑induced acute liver damage: An in vivo study and molecular modeling 

Anca Hermenean, Teodora Mariasiu, Inmaculada Navarro-González, Josefina Vegara-Meseguer, Eftimie Miuțescu, Sandipan Chakraborty, Horacio Pérez-Sánchez
Article Number: 73
Published online on: 21 January 2026

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Retraction Open Access

[Retracted] Gambogic acid suppresses colon cancer cell activity in vitro

Zailong Zhou, Jian Ma
Article Number: 72
Published online on: 19 January 2026

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Case Report

Identification of a novel KISS1R (GPR54) gene variant (c.505+2T>G) in a patient with congenital hypogonadotropic hypogonadism: A case report and literature review

Burak Menekse, Enes Ucgul, Abdullatif Bakir, Sema Hepsen, Ilknur Ozturk Unsal, Muhammed Kizilgul, Takako Araki, Erman Cakal
Article Number: 71
Published online on: 16 January 2026

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Postoperative hypofractionated intensity-modulated proton therapy to control recurrent paraganglioma at the jugular foramen: A case report and literature review

Wei Wang, Yingxia Yuan, Jiwei Bai, Yue Zou, Dongxue Zhou, Jun Zhao, Shuyan Zhang, Zishen Wang, Jie Wang, Jingjing Kong, Lu Yang, Masashi Mizumoto, Hideyuki Sakurai, Shosei Shimizu
Article Number: 70
Published online on: 16 January 2026

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Article

Serum antithrombin III level predicts acute kidney injury in patients with traumatic brain injury

Ruoran Wang, Min He, Jianguo Xu
Article Number: 69
Published online on: 16 January 2026

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Retraction Open Access

[Retracted] β‑asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal‑regulated kinase signaling pathway

Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong Li
Article Number: 68
Published online on: 12 January 2026

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Case Report Open Access

Rare co‑occurrence of gastrointestinal stromal tumors and leiomyomas: A case report and review of the literature

Yu Zhang, Xiaoqiong Shi, Wenfu Xie, Meilin He, Shan Zhang, Xue Peng, Hao Lei, Xulei Li, Haiying Liu, Qiao Shu, Fangyuan Zou, Mingyong Wei
Article Number: 67
Published online on: 09 January 2026

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No increased risk of hepatic enzyme abnormalities with non‑peptidic thrombopoietin receptor agonists in immune thrombocytopenia: A meta‑analysis of randomized controlled trials

Nan Shen, Rang Wu, Tiantian Lu, Song Liu, Yazhou Jiang, Jingjing Yan, Tao Ning, Chang Dong, Jianqin Li, Suyue Zhu
Article Number: 66
Published online on: 09 January 2026

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Case Report

Submucosal colonic fecalith mimicking a submucosal malignant tumor at the anastomotic site after colon cancer: A case report

Motoaki Yuhi, Masatsugu Hiraki, Shin Takesue, Mariko Hashiguchi, Megumi Nishiyama, Yoshiaki Egashira, Tatsuya Manabe, Hirokazu Noshiro
Article Number: 65
Published online on: 08 January 2026

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Article

Clinical characteristics of acute primary angle closure following COVID‑19 during the Omicron outbreak in China

Jianhui Zhang, Yingying Xue, Liu Zhang, Yuhong Wang, Shancheng Si
Article Number: 64
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Aberrant expression and mechanism of miR‑130b‑3p/phosphatase and tensin homolog in nephroblastoma in children

Yifeng Hu, Jingtie Yan
Article Number: 63
Published online on: 05 January 2026

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Case Report Open Access

Novel variants in STAG2 and PKD1 associate with multiple congenital malformations and autosomal dominant polycystic kidney disease in a Chinese family: A case report and literature review

Qi Yang, Qiang Zhang, Sheng Yi, Xunzhao Zhou, Yiyan Ruan, Shujie Zhang, Shang Yi, Qinle Zhang, Zailng Qin, Jingsi Luo
Article Number: 62
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 31 Issue 4

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Impact Factor: 2.3

Case Report

Sagittal sinus thrombosis in pregnancy: A case report

Zaheera Saadia, Misbah Ilyas, Jayd Saud Althwiny, Fai Alaqel, Alanoud Abdullah Alsufayri, Lujain Husain Almutairi
Article Number: 100
Published online on: 05 February 2026

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Article

Elevated PGE2 and COX‑2 expression in villous adenoma: Implications for electrolyte depletion syndrome

Shiki Fujino, Hiroyuki Fukuda, Katsuki Danno, Takashi Takeda, Masaya Higashiguchi, Kozo Noguchi, Takefumi Hirao, Aya Ito, Norikatsu Miyoshi, Yoshio Oka
Article Number: 99
Published online on: 04 February 2026

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Wogonin as a potential therapeutic agent for psoriasis: Core target identification and validation

Yu Lu, Xiaomei Zhou, Yiyu Guo, Fengrui Zhang, Jirong Wang, Jinhong Ge, Yan Xiao, Dengke Yang
Article Number: 98
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Glibenclamide exacerbates adriamycin‑induced cardiotoxicity by activating oxidative stress‑induced endoplasmic reticulum stress in rats

Meng-Lin Liu, Meng-Long Wang, Jing-Jun Lv, Jie Wei, Jun Wan
Article Number: 97
Published online on: 04 February 2026

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Review

Key role of the autonomic nervous system in breast cancer (Review)

Min Wu, Zhiwu Zhang, Lu Zhou, Shiqi Liu, Qing Chen, Cui Guo, Shasha Zhao, Xuedan Chen
Article Number: 96
Published online on: 04 February 2026

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Senescent hepatic stellate cells drive inflammation and disease progression in MASH (Review)

Zhiqi Han, Yiran She, Di Wu, Nuo Zhang, Zheyuan Liu, Zhongyuan Wang, Xiaoying Zhou, Shuo Li
Article Number: 95
Published online on: 04 February 2026

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PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells

Zilong Zhang, Hangyu Zhou, Diliyaer Adili, Wei Zhu, Yong Liu, Wenzheng Zhou, Zhao Wang, Jie Li
Article Number: 94
Published online on: 04 February 2026

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Case Report

A novel human papillomavirus‑induced ‘doughnut wart’ lesion treated with 5‑aminolevulinic acid photodynamic therapy: A case report

Ke Li, Yitao Qian, Wenjing Zha, Lei Shi
Article Number: 93
Published online on: 04 February 2026

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Case Report Open Access

Comprehensive diagnosis and individualized treatment of multiple primary lung cancer: A case report

Guoxiong Zeng, Yunyan Zhou, Wang Wan, Biao Deng, Chunyuan Chen, Zhu Liang
Article Number: 92
Published online on: 03 February 2026

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Pathophysiological mechanisms of fatigue and multidisciplinary management strategies (Review)

Hong Zhou, Wenwen Yu, Jiaming Lei, Runzhi Chang, Yingjia Cheng, Guorui Wang, Li Lin
Article Number: 91
Published online on: 03 February 2026

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Case Report Open Access

A rare upstream regulatory region mutation in APC presenting as classical familial adenomatous polyposis: A case report and literature review

Chi-Han Yang, Yen-Cheng Chen, Tsung-Kun Chang, Wei-Chih Su, Ching-Wen Huang, Hsiang-Lin Tsai, Jaw-Yuan Wang
Article Number: 90
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] lncRNA MIAT promote cell invasion and migration in esophageal cancer

Weiguo Zhang, Qiang Chen, Caipeng Lei
Article Number: 89
Published online on: 02 February 2026

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Review Open Access

Mitochondria‑driven ferroptosis in intervertebral disc degeneration: A novel target in age‑related spinal diseases (Review)

Yang Hou, Xiaolei Yang, Duorun Qiu, Lei Liu, Jiangang Shi, Yongfei Guo
Article Number: 88
Published online on: 02 February 2026

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Case Report

Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report

Jingxian Li, Fang Wang, Yuanshu Du, Yonghui Wang
Article Number: 87
Published online on: 02 February 2026

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Case Report Open Access

Gastric wall thickening and gastric outlet obstruction due to peritoneal metastasis in breast cancer: A case report

Bin He, Lin Ling Li, Ting Yu, Yu Tan, Ling Zhang
Article Number: 86
Published online on: 29 January 2026

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Article Open Access

Myrrh ameliorates endometriosis by enhancing ER stress‑related apoptotic cell death

Bo-Sung Kim, Minkyoung Cho, Jung Ho Han, Jung-Sook Jin, Sung-Jin Bae, Yunju Jo, Dongryeol Ryu, Yerim Joo, Seon Beom Kim, Jongkil Joo, Inhye Kim, Ki-Tae Ha
Article Number: 85
Published online on: 29 January 2026

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