Castleman's disease in the pelvic retroperitoneum: A case report

Zhao,Qingli; Zhang,Xuebei; Yang,Xiaoqing; Huang,Shengliang

doi:10.3892/etm.2022.11596

Castleman's disease in the pelvic retroperitoneum: A case report

Authors:
- Qingli Zhao
- Xuebei Zhang
- Xiaoqing Yang
- Shengliang Huang
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Affiliations: Department of Urology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan, Shandong 250014, P.R. China, Nursing Department, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250001, P.R. China, Department of Pathology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan, Shandong 250014, P.R. China
Published online on: September 7, 2022 https://doi.org/10.3892/etm.2022.11596
Article Number: 660

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Abstract

Castleman's disease (CD) is an uncommon lymphoproliferative disorder, which mostly occurs in the chest and neck. Lesions originating in the pelvic retroperitoneum are rare. It is important to consider CD as a differential diagnosis when a pelvic lesion is found. The present study reports a unique case of CD in the pelvic retroperitoneum, where the tumor was demonstrated to have a highly vascular nature on CT scanning. The preoperative diagnosis was uncertain and a vascular‑derived tumor was considered. Laparoscopic surgery was performed and the mass was completely resected along with regional lymphadenectomy. The pathological diagnosis was the hyaline vascular type of CD. The patient was free of recurrence after 1 year of follow‑up. As the underlying etiology remains elusive and the differential diagnosis is challenging preoperatively, surgical excision is the preferred treatment strategy for this type of benign lesion.

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