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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2022 Volume 24 Issue 5

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Impact Factor: 2.3

Review Open Access

New‑onset neuropsychiatric sequelae and ‘long‑COVID’ syndrome (Review)

Vasiliki Efstathiou, Maria-Ioanna Stefanou, Marina Demetriou, Nikolaos Siafakas, Eleni Katsantoni, Michael Makris, Georgios Tsivgoulis, Vassilios Zoumpourlis, Stylianos P. Kympouropoulos, James N. Tsoporis, Demetrios A. Spandidos, Panagiotis Ferentinos, Nikolaos Smyrnis, Emmanouil Rizos
Article Number: 705
Published online on: 04 October 2022

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Article Open Access

Prognostic significance of HER2 status evaluation using immunohistochemistry in patients with urothelial carcinoma of the bladder: A retrospective single‑center experience

Xuesong Bai, Weiyang He, Hubin Yin, Xinyuan Li, Xiang Zhou, Zongjie Wei, Haitao Yu, Xin Gou
Article Number: 704
Published online on: 04 October 2022

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Article Open Access

Neutrophil‑to‑lymphocyte, platelet‑to‑lymphocyte and lymphocyte‑to‑monocyte ratios are associated with amputation rates in patients with peripheral arterial disease and diabetes mellitus who underwent revascularization: A Romanian regional center study

Mircea Catalin Cosarca, Ioana Hălmaciu, Adrian Vasile Muresan, Bogdan Andrei Suciu, Calin Molnar, Eliza Russu, Emoke Horvath, Raluca Niculescu, Lucian Puscasiu, Nicolae Bacalbașa, Irina Balescu, Ioan Teodor Bud
Article Number: 703
Published online on: 03 October 2022

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Article Open Access

Protective effects of endothelial progenitor cell microvesicles carrying miR‑98‑5p on angiotensin II‑induced rat kidney cell injury

Huade Mai, Zhihua Huang, Xiaodian Zhang, Yuanyuan Zhang, Juming Chen, Minghui Chen, Yunbo Zhang, Yanling Song, Bingshu Wang, Yunyun Lin, Shenhong Gu
Article Number: 702
Published online on: 29 September 2022

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Article Open Access

Synergistic value of fractional flow reserve and low‑density non‑calcified plaque based on coronary computed tomography angiography for the identification of lesion‑specific ischemia

Lin-Meng Tang, Feng Liu, Ting-Yu Dong, Fei Yang, Shu-Jun Cui
Article Number: 701
Published online on: 29 September 2022

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Case Report Open Access

Wide local excision for Merkel cell carcinoma of the lower extremity: A case report

Yong Zhang, Yan Sun, Juefei Mo
Article Number: 700
Published online on: 29 September 2022

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Article Open Access

Cardiovascular adaptations and inflammation in marathon runners

Konstantinos Tsarouhas, Christina Tsitsimpikou, Antonios Samaras, Christos Saravanis, Genovefa Kolovou, Flora Bacopoulou, Demetrios A. Spandidos, Dimitrios Kouretas
Article Number: 699
Published online on: 29 September 2022

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Article

Role of biological markers and CT severity score in predicting mortality in patients with COVID‑19: An observational retrospective study

Samuel-Bogdan Todor, Victoria Bîrluțiu, Diana Topîrcean, Romeo-Gabriel Mihăilă
Article Number: 698
Published online on: 28 September 2022

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Case Report Open Access

Right atrial lipoma: A case report and literature review

Mircea Bajdechi, Sebastian Onciul, Victor Costache, Sergiu Brici, Adriana Gurghean
Article Number: 697
Published online on: 28 September 2022

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Article Open Access

A retrospective study from a single center of 252 patients who underwent elective pancreaticoduodenectomy to compare perioperative hemodynamic optimization therapy and usual protocols in terms of perioperative cardiac function

Lian Lian, Yi Wang, Xueqin Ning
Article Number: 696
Published online on: 28 September 2022

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Article

Adapting surgical ‘bundles’ to prevent surgical site infections in obstetrics and gynecology (Review)

Aida Petca, Ioana Cristina Rotar, Andreea Borislavschi, Razvan-Cosmin Petca, Razvan Alexandru Danau, Mihai Cristian Dumitrascu, Florica Sandru, Irina Pacu
Article Number: 695
Published online on: 28 September 2022

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Article

Thymoquinone‑induced autophagy mitigates doxorubicin‑induced H9c2 cell apoptosis

Dawei Liu, Lei Zhao
Article Number: 694
Published online on: 28 September 2022

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Article Open Access

Biomarkers predicting the 30‑day mortality of patients who underwent elective surgery and were infected with SARS‑CoV‑2 during the post‑operative period: A retrospective study

Vasiliki Epameinondas Georgakopoulou, Dimitrios Basoulis, Pantazis M. Voutsinas, Chrysovalantis V. Papageorgiou, Irene Eliadi, Georgios Karamanakos, Demetrios A. Spandidos, Nikolaos Mathioudakis, Petros Papalexis, Stavros Papadakos, George Fotakopoulos, Kyriakos Tarantinos, Nikolaos V. Sipsas
Article Number: 693
Published online on: 27 September 2022

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Case Report

EUS‑FNA combined with an intracapsular injection of antibiotics and ethanol for posterior mediastinal cyst: A case report

Linghong Wu, Xianwen Zhang, Maosen Feng, Xiaoan Li
Article Number: 692
Published online on: 27 September 2022

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Article Open Access

Acute hepatitis and liver injury in hospitalized patients with COVID‑19 infection

Vasiliki Epameinondas Georgakopoulou, Triada Bali, Magdalini Adamantou, Stavroula Asimakopoulou, Sotiria Makrodimitri, Stamatia Samara, Maria Triantafyllou, Pantazis M. Voutsinas, Irene Eliadi, Georgios Karamanakos, Dimitrios Basoulis, Odysseas Chatzipanagiotou, Eleni Adamopoulou, Antonia Alevizou, Menelaos Athanasiadis, Demetrios A. Spandidos, Petros Papalexis, Kyriakos Tarantinos, Nikolaos V. Sipsas, Michael Samarkos, Evangelos Cholongitas
Article Number: 691
Published online on: 26 September 2022

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Retraction Open Access

[Retracted] Suppression of oxidative stress in endothelial progenitor cells promotes angiogenesis and improves cardiac function following myocardial infarction in diabetic mice

Peng Jin, Tao Li, Xueqi Li, Xinghua Shen, Yanru Zhao
Article Number: 690
Published online on: 26 September 2022

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Review Open Access

Seizures and multiple sclerosis‑more than an epidemiological association (Review)

Dorin Cristian Antal, Thomas Gabriel Schreiner, Theona Eliza Crihan, Bogdan Emilian Ignat, Victoria San Antonio‑Arce, Iulian Dan Cuciureanu
Article Number: 689
Published online on: 23 September 2022

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Article Open Access

Novel variants identified in a three‑generation family with concomitant exotropia

Jiaxun Li, Yishi Ma, Wentao Zhou, Wenchao Lyu, Liming Wang, Song Mao, Jin Li, Xuefeng Shi
Article Number: 688
Published online on: 23 September 2022

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Article Open Access

MG132 protects against lung injury following brain death in rats

Huijuan Shi, Dongjing Yang, Zhongkun Huo, Yuexia Li, Wenzhi Guo, Shuijun Zhang
Article Number: 687
Published online on: 23 September 2022

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Correction Open Access

[Corrigendum] Suppression of SIPA‑1 expression may reduce bladder cancer invasion and metastasis via the downregulation of E‑cadherin and ZO‑1

Ping Zhang, Xinghuan Wang
Article Number: 686
Published online on: 23 September 2022

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Article Open Access

Clinical and radiomic factors for predicting invasiveness in pulmonary ground‑glass opacity

Yutao Dang, Ruotian Wang, Kun Qian, Jie Lu, Yi Zhang
Article Number: 685
Published online on: 22 September 2022

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Article Open Access

Chemerin promotes MAPK/ERK activation to induce inflammatory factor production in rat synoviocytes

Chen Wang, Songrui Zhang, Longao Huang, Jianyi Liu, Quan Zhou, Gang Du, Shan Lao
Article Number: 684
Published online on: 22 September 2022

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Article Open Access

KIF2A participates in the progression of hepatocellular carcinoma and angiogenesis by interacting with Notch1

Qi Wu, Xuting Ren, Yun Chen, Ye Jin, Xiaobo Zhan, Changfeng Liu, Bing Zhang
Article Number: 683
Published online on: 22 September 2022

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Article Open Access

Age‑related differences for expression of the nerve‑specific proteins after peripheral nerve injury

Hiroyuki Obata, Kiyohito Naito, Ayaka Kikui, Shinji Nakamura, Kaori Suzuki, So Kawakita, Takamaru Suzuki, Kenji Goto, Nana Nagura, Yoichi Sugiyama, Isao Nagaoka, Muneaki Ishijima
Article Number: 682
Published online on: 21 September 2022

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Case Report

Anti‑PD‑1 immune checkpoint inhibitor inducing endocrine toxicity in a patient with advanced lung cancer: A case report and literature review

Suqing Bao, Xia Jiang
Article Number: 681
Published online on: 21 September 2022

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Article Open Access

Identifying potential therapeutic targets for ischemic stroke through immune infiltration analysis and construction of a programmed cell death‑related ceRNA network

Yiteng Cui, Xin Zhou, Pingping Meng, Shanshan Dong, Ziwei Wang, Tongye Liu, Xiaomin Liu, Yunteng Cui, Yuyang Wang, Qiang Wang
Article Number: 680
Published online on: 21 September 2022

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Article Open Access

TIM4/NLRP3 axis participates in the effects of M1 macrophages on inflammatory factor release, apoptosis and cell adhesion in thyroid follicular cells

Yongjun Cao, Yumeng Sun, Xiaowen Jin, Xiaoqian Li, Le Chen, Yan Qiu
Article Number: 679
Published online on: 20 September 2022

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Article Open Access

Multi‑locus sequence and drug resistance analysis of Salmonella infection in children with diarrhea in Guangdong to identify the dominant ST and cause of antibiotic‑resistance

Lingqing Xu, Qianjun He, Yinxian Tang, Weihong Wen, Linjuan Chen, Yuzhen Li, Changhong Yi, Bishi Fu
Article Number: 678
Published online on: 20 September 2022

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Case Report Open Access

Monkeypox 2022: Dermatologists in the frontline on the edge of a new pandemic: A case report

Ana Cutoiu, Daniel Boda
Article Number: 677
Published online on: 20 September 2022

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Review Open Access

Properties of flavonoids in the treatment of bladder cancer (Review)

Yue Lv, Zhonghao Liu, Haixing Jia, Youcheng Xiu, Zan Liu, Leihong Deng
Article Number: 676
Published online on: 19 September 2022

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Article

Onodera's prognostic nutritional index: Comparison of its role in the severity and outcomes of patients with COVID‑19 during the periods of alpha, delta and omicron variant predominance

Nikolaos Mathioudakis, Marinos Zachiotis, Stavros Papadakos, Maria Triantafyllou, Amalia Karapanou, Stamatia Samara, Georgios Karamanakos, Demetrios A. Spandidos, Petros Papalexis, Christos Damaskos, Kyriakos Tarantinos, George Fotakopoulos, Pagona Sklapani, Nikolaos Trakas, Nikolaos V. Sipsas, Vasiliki Epameinondas Georgakopoulou
Article Number: 675
Published online on: 16 September 2022

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Review Open Access

Role of Takeda G protein‑coupled receptor 5 in microvascular endothelial cell dysfunction in diabetic retinopathy (Review)

Miao Zhang, Zhenghao Dong, Wenkang Dong, Dongdong Zhou, Xiang Ren
Article Number: 674
Published online on: 15 September 2022

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Article Open Access

Ac2‑26 alleviates hepatic ischemia‑reperfusion injury based on inhibiting the positive feedback loop of HMGB1/TLR4/NF‑κB/neutrophils

Chen Bai, Zhengchen Jiang, Hongxin Jiang, Shuna Yu, Ming Li, Fangfang Chu, Yaxin Sheng, Jianguo Li, Jiying Jiang, Wanzhen Li
Article Number: 673
Published online on: 14 September 2022

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Article Open Access

Long non‑coding RNA MALAT1 promotes cell proliferation, migration and invasion by targeting miR‑590‑3p in osteosarcoma

Hui Zhao, Yongping Wang, Weihua Hou, Xuanxi Ding, Wenji Wang
Article Number: 672
Published online on: 14 September 2022

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Article Open Access

Pre‑existing renal insufficiency synchronous with high preoperative neutrophil‑to‑lymphocyte ratio as a risk factor of intravesical recurrence in patients with pure upper tract urothelial carcinoma after radical nephroureterectomy

Tsung-Han Cheng, Che-Yuan Hu, Kuan-Yu Wu, Ta-Yao Tai, Han-Yu Weng, Wen-Horng Yang, Chien-Hui Ou, Hau-Chern Jan
Article Number: 671
Published online on: 13 September 2022

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Article Open Access

Transcriptome analysis in an AEG‑1‑deficient neuronal HT22 cell line

Kunmei Liu, Panpan Wan, Yue Huang, Bin Wang, Xuequan Wang, Rui Zhang, Le Guo
Article Number: 670
Published online on: 13 September 2022

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Case Report

Life-threatening anemia due to uterine fibroids: A case series

Michiko Kawano, Mamiko Okamoto, Mitsutake Yano, Yasushi Kawano
Article Number: 669
Published online on: 12 September 2022

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Article Open Access

Inositol monophosphatase 2 promotes epithelial ovarian cancer cell proliferation and migration by regulating the AKT/mTOR signaling pathway

Tangnur Ablimit, Gulxan Tursun, Yuanyuan Zhang, Guzalnur Abduxkur, Gulgina Abdurexit, Guzalnur Abliz
Article Number: 668
Published online on: 12 September 2022

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Article Open Access

Asiaticoside delays senescence and attenuate generation of ROS in UV‑exposure cells through regulates TGF‑β1/Smad pathway

Honghao Jiang, Xiaoyong Zhou, Liuqing Chen
Article Number: 667
Published online on: 08 September 2022

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Article Open Access

Circulating levels of DDIT4 and mTOR, and contributions of BMI, inflammation and insulin sensitivity in hyperlipidemia

Xinyan Pan, Zhimei Zhang, Chunqiao Liu, Ming Zhao, Xing Wang, Junqing Zhai, Chao Wang, Guangyao Song
Article Number: 666
Published online on: 08 September 2022

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Case Report Open Access

Uterine adenomyotic cyst with markedly elevated serum CA19‑9 and CA125 levels: A case report

Lihua Zheng, Li Shan, Fengfeng Cai
Article Number: 665
Published online on: 07 September 2022

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Case Report

Lipomatous mixed tumor of the skin with cystic formation affecting the upper lip: A case report

Ryoko Nagano, Shinsuke Fujii, Hiroko Wada, Mayu Matsumura‑Κawashima, Yurie Mikami, Masafumi Moriyama, Toru Chikui, Kazunori Yoshiura, Seiji Nakamura, Tamotsu Kiyoshima
Article Number: 664
Published online on: 07 September 2022

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Article Open Access

Application of rapid on‑site evaluation in computed tomography‑guided percutaneous transthoracic needle biopsy of pulmonary nodules of ≤2.0 cm in diameter

Dongxu Wang, Qing Zhang, Yuguang Wang, Wei Dou, Guoxu Ding, Qiuting Wen, Ying Han, Youli Du, Bo Li
Article Number: 663
Published online on: 07 September 2022

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Article Open Access

SIRT3 expression alleviates microglia activation‑induced dopaminergic neuron injury through the mitochondrial pathway

De-Qi Jiang, Qing-Min Zang, Li-Lin Jiang, Cheng-Shu Lu, Shi-Hua Zhao, Lan-Cheng Xu
Article Number: 662
Published online on: 07 September 2022

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Case Report Open Access

Vaginal leiomyoma: A case report

Ying Gao, Yujie Qin, Jing Li, Jun Qian, Jiaxi Yao
Article Number: 661
Published online on: 07 September 2022

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Case Report

Castleman's disease in the pelvic retroperitoneum: A case report

Qingli Zhao, Xuebei Zhang, Xiaoqing Yang, Shengliang Huang
Article Number: 660
Published online on: 07 September 2022

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Case Report Open Access

Response to immunotherapy in a patient with advanced epithelioid sarcoma of adrenal gland: A case report

Jingwen Wang, Chen Lu, Xi Tang
Article Number: 659
Published online on: 07 September 2022

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Case Report Open Access

Metabolic alkalosis‑an adverse effect of baking soda misuse: A case report and literature review

Anca Diaconu, Ioana Florea, Cristiana-Elena Vlad, Răzvan Achiței, Laura Florea
Article Number: 658
Published online on: 07 September 2022

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Article Open Access

Metabolomic study of eyeball rupture and patients with cataracts in aqueous humor

Qingquan Wei, Liyin Luo, Wei Qiu, Yingying Gong, Yanyun Jiang
Article Number: 657
Published online on: 07 September 2022

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Article Open Access

Bioinformatics analysis identification of AKT3 and RAC1 as key genes in postmenopausal osteoporosis

Liyong Zhang, Xiaoming Li, Chunfei Wan, Weiwei Da, Jun Zhang, Lihong Fan, Qiang Fu, Shunmin Xing, Yongxiang Wang
Article Number: 656
Published online on: 07 September 2022

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Article Open Access

Human placental mesenchymal stem cells regulate inflammation via the NF‑κB signaling pathway

Youyi Liu, Xiading Zhang, Yiwei Hu, Mingzhu Kang, Yibo Wu, Yuan Wang, Chao Deng
Article Number: 654
Published online on: 07 September 2022

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Article Open Access

Clinical relevance of serum procalcitonin in patients with aneurysmal subarachnoid hemorrhage

Jong Ho Kim, Ho Jun Yi, Bum-Tae Kim, Dong-Seong Shin
Article Number: 653
Published online on: 06 September 2022

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Article

Relationship of miRNA‑126 and miRNA‑122 expression with type 2 diabetes mellitus and related glucose metabolism parameters: A systematic review and meta‑analysis

Yaling He, Yuqian Li, Zhihan Zhai, Pengling Liu, Luting Nie, Yiquan Zheng, Jian Hou, Wenqian Huo, Zhenxing Mao, Zhenzhong Zhang, Chongjian Wang, Xiaotian Liu
Article Number: 652
Published online on: 05 September 2022

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Retraction Open Access

[Retracted] MicroRNA‑877 inhibits cell proliferation and invasion in non‑small cell lung cancer by directly targeting IGF‑1R

Guohua Zhou, Jinglian Xie, Zikun Gao, Weishen Yao
Article Number: 651
Published online on: 05 September 2022

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Case Report

ALK‑positive locally advanced lung cancer in a patient who achieved long‑term complete response with crizotinib: A case report

Levent Emi̇rzeoglu, Ozgur Olmez
Article Number: 650
Published online on: 02 September 2022

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Article Open Access

Functional prediction and profiling of exosomal circRNAs derived from seminal plasma for the diagnosis and treatment of oligoasthenospermia

Dezhi Yue, Ruipeng Yang, Chengliang Xiong, Ruifeng Yang
Article Number: 649
Published online on: 02 September 2022

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Article Open Access

Inhibition of lysyl oxidase‑like 2 ameliorates folic acid‑induced renal tubulointerstitial fibrosis

Sung-Eun Choi, Nara Jeon, Hoon Young Choi, Hyeon Joo Jeong, Beom Jin Lim
Article Number: 648
Published online on: 02 September 2022

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Article Open Access

Olanzapine enhances adipogenesis and suppresses lipolysis in 3T3‑L1 adipocytes under low‑glucose and weak differentiation/maturation conditions

Taisuke Matsuo, Yuzuki Omori, Takashi Tomita, Yasuyuki Sadzuka
Article Number: 647
Published online on: 01 September 2022

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Article

S100A9‑containing serum exosomes obtained from patients with burn injuries promote myocardial cell pyroptosis through NLRP3

Aili Wang, Ni Zheng, Qing Jia, Yu Chen, Shun Xu
Article Number: 646
Published online on: 01 September 2022

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Case Report Open Access

Minimally invasive complete urinary tract drainage in the treatment of vesicovaginal fistula: A case report

Shenghao Niu, Yunpeng Li, Song Tu, Shijie Niu, Jun Qian, Faying Yang, Jiaxi Yao
Article Number: 645
Published online on: 01 September 2022

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MicroRNA‑203a‑3p suppresses endothelial cell proliferation and invasion, and promotes apoptosis in hemangioma by inactivating the VEGF‑mediated PI3K/AKT pathway

Zhenfeng Hu, Lei Zhuo, Yanling Li, Dongpeng Duan, Jing Guo
Article Number: 644
Published online on: 01 September 2022

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March-2026 Volume 31 Issue 3

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Impact Factor: 2.3

Article Open Access

Effect of SGLT2 inhibitors on heart failure outcomes in patients with and without diabetes: A systematic review and meta‑analysis of randomized controlled trials

Duaa Abdullah Bafail, Noura Hamdi Alhalees
Article Number: 84
Published online on: 28 January 2026

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Article Open Access

Exploring the protective mechanisms and therapeutic potential of carnosic acid against acute respiratory distress syndrome through molecular docking, molecular dynamics and experimental verification

Quan Li, Lili Ding, Haijun Sun, Weichao Ding, Mengmeng Wang, Zhaorui Sun, Congxue Ma
Article Number: 83
Published online on: 28 January 2026

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Review

Exploring the roots of schizophrenia: Current research and future directions (Review)

Shuang Lv, Chunxia Luo
Article Number: 82
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] miR‑146a‑5p protects against renal injury in MRL/lpr mice via improvement of the Treg/Th17 imbalance by targeting the TRAF6/NF‑κB axis

Jiajia Teng, Feng Yang, Xiaoling Li
Article Number: 81
Published online on: 28 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑24‑3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl‑2‑like protein 11

Huanxin Zhang, Shizhen Xue, Yi Feng, Jun Shen, Jixian Zhao
Article Number: 80
Published online on: 26 January 2026

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Efficacy and safety of unilateral biportal endoscopy vs. percutaneous endoscopic interlaminar approach in lumbar disc herniation: A meta‑analysis​

Yuhao Gao, Fangzheng He, Ji Wen, Shilei Qin, Pengfei Han, Yunfeng Xu
Article Number: 79
Published online on: 23 January 2026

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Case Report Open Access

Intralobar pulmonary sequestration coexisting with pulmonary cryptococcosis: A case report and literature review

Dan Cheng, Yue Wang, Jun Li, Dan Yu, Yunyun Wang, Jinbo Fan, Jiankun Wang, Liqun He
Article Number: 78
Published online on: 23 January 2026

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Article Open Access

Tumor‑associated macrophages suppress estrogen receptor‑β expression in triple‑negative breast cancer through the PI3K/AKT pathway

Qiulei Zhang, Di Guo, Gaoran Xu, Rong Xie, Yuqing Deng, Peng Fu, Jinnan Wan
Article Number: 77
Published online on: 21 January 2026

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Article Open Access

Development of a diagnostic model for esophageal achalasia assessed by esophageal high‑resolution manometry using artificial intelligence

Maiko Tabuchi, Yasuhiko Nakao, Hitomi Minami, Hiroko Inomata, Junya Shiota, Taro Akashi, Keiichi Hashiguchi, Moto Kitayama, Kayoko Matsushima, Naoyuki Yamaguchi, Yuko Akazawa, Hisamitsu Miyaaki
Article Number: 76
Published online on: 21 January 2026

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Case Report

Use of metagenomic next‑generation sequencing to diagnose Tropheryma whipplei infection‑related pneumonia: A case report

Yutu Luo, Haibing Ding, Jiahua Pan, Guangyang Xu
Article Number: 75
Published online on: 21 January 2026

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Effect of rivaroxaban on DNA damage in an ischemia-reperfusion model: Evaluation of 8‑OHdG levels

Ceren Sayarer, Abidin Cenk Erdal, Tuğra Gençpinar, Özlem Gürsoy Doruk, Tuncay Küme
Article Number: 74
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Hepatoprotective activity of chrysin is mediated through TNF‑α in chemically‑induced acute liver damage: An in vivo study and molecular modeling 

Anca Hermenean, Teodora Mariasiu, Inmaculada Navarro-González, Josefina Vegara-Meseguer, Eftimie Miuțescu, Sandipan Chakraborty, Horacio Pérez-Sánchez
Article Number: 73
Published online on: 21 January 2026

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Retraction Open Access

[Retracted] Gambogic acid suppresses colon cancer cell activity in vitro

Zailong Zhou, Jian Ma
Article Number: 72
Published online on: 19 January 2026

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Case Report

Identification of a novel KISS1R (GPR54) gene variant (c.505+2T>G) in a patient with congenital hypogonadotropic hypogonadism: A case report and literature review

Burak Menekse, Enes Ucgul, Abdullatif Bakir, Sema Hepsen, Ilknur Ozturk Unsal, Muhammed Kizilgul, Takako Araki, Erman Cakal
Article Number: 71
Published online on: 16 January 2026

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Postoperative hypofractionated intensity-modulated proton therapy to control recurrent paraganglioma at the jugular foramen: A case report and literature review

Wei Wang, Yingxia Yuan, Jiwei Bai, Yue Zou, Dongxue Zhou, Jun Zhao, Shuyan Zhang, Zishen Wang, Jie Wang, Jingjing Kong, Lu Yang, Masashi Mizumoto, Hideyuki Sakurai, Shosei Shimizu
Article Number: 70
Published online on: 16 January 2026

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Article

Serum antithrombin III level predicts acute kidney injury in patients with traumatic brain injury

Ruoran Wang, Min He, Jianguo Xu
Article Number: 69
Published online on: 16 January 2026

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Retraction Open Access

[Retracted] β‑asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal‑regulated kinase signaling pathway

Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong Li
Article Number: 68
Published online on: 12 January 2026

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Case Report Open Access

Rare co‑occurrence of gastrointestinal stromal tumors and leiomyomas: A case report and review of the literature

Yu Zhang, Xiaoqiong Shi, Wenfu Xie, Meilin He, Shan Zhang, Xue Peng, Hao Lei, Xulei Li, Haiying Liu, Qiao Shu, Fangyuan Zou, Mingyong Wei
Article Number: 67
Published online on: 09 January 2026

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Article Open Access

No increased risk of hepatic enzyme abnormalities with non‑peptidic thrombopoietin receptor agonists in immune thrombocytopenia: A meta‑analysis of randomized controlled trials

Nan Shen, Rang Wu, Tiantian Lu, Song Liu, Yazhou Jiang, Jingjing Yan, Tao Ning, Chang Dong, Jianqin Li, Suyue Zhu
Article Number: 66
Published online on: 09 January 2026

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Case Report

Submucosal colonic fecalith mimicking a submucosal malignant tumor at the anastomotic site after colon cancer: A case report

Motoaki Yuhi, Masatsugu Hiraki, Shin Takesue, Mariko Hashiguchi, Megumi Nishiyama, Yoshiaki Egashira, Tatsuya Manabe, Hirokazu Noshiro
Article Number: 65
Published online on: 08 January 2026

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Article

Clinical characteristics of acute primary angle closure following COVID‑19 during the Omicron outbreak in China

Jianhui Zhang, Yingying Xue, Liu Zhang, Yuhong Wang, Shancheng Si
Article Number: 64
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Aberrant expression and mechanism of miR‑130b‑3p/phosphatase and tensin homolog in nephroblastoma in children

Yifeng Hu, Jingtie Yan
Article Number: 63
Published online on: 05 January 2026

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Case Report Open Access

Novel variants in STAG2 and PKD1 associate with multiple congenital malformations and autosomal dominant polycystic kidney disease in a Chinese family: A case report and literature review

Qi Yang, Qiang Zhang, Sheng Yi, Xunzhao Zhou, Yiyan Ruan, Shujie Zhang, Shang Yi, Qinle Zhang, Zailng Qin, Jingsi Luo
Article Number: 62
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 31 Issue 4

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Impact Factor: 2.3

Case Report

Sagittal sinus thrombosis in pregnancy: A case report

Zaheera Saadia, Misbah Ilyas, Jayd Saud Althwiny, Fai Alaqel, Alanoud Abdullah Alsufayri, Lujain Husain Almutairi
Article Number: 100
Published online on: 05 February 2026

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Article

Elevated PGE2 and COX‑2 expression in villous adenoma: Implications for electrolyte depletion syndrome

Shiki Fujino, Hiroyuki Fukuda, Katsuki Danno, Takashi Takeda, Masaya Higashiguchi, Kozo Noguchi, Takefumi Hirao, Aya Ito, Norikatsu Miyoshi, Yoshio Oka
Article Number: 99
Published online on: 04 February 2026

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Article Open Access

Wogonin as a potential therapeutic agent for psoriasis: Core target identification and validation

Yu Lu, Xiaomei Zhou, Yiyu Guo, Fengrui Zhang, Jirong Wang, Jinhong Ge, Yan Xiao, Dengke Yang
Article Number: 98
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Glibenclamide exacerbates adriamycin‑induced cardiotoxicity by activating oxidative stress‑induced endoplasmic reticulum stress in rats

Meng-Lin Liu, Meng-Long Wang, Jing-Jun Lv, Jie Wei, Jun Wan
Article Number: 97
Published online on: 04 February 2026

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Review

Key role of the autonomic nervous system in breast cancer (Review)

Min Wu, Zhiwu Zhang, Lu Zhou, Shiqi Liu, Qing Chen, Cui Guo, Shasha Zhao, Xuedan Chen
Article Number: 96
Published online on: 04 February 2026

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Review Open Access

Senescent hepatic stellate cells drive inflammation and disease progression in MASH (Review)

Zhiqi Han, Yiran She, Di Wu, Nuo Zhang, Zheyuan Liu, Zhongyuan Wang, Xiaoying Zhou, Shuo Li
Article Number: 95
Published online on: 04 February 2026

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Article Open Access

PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells

Zilong Zhang, Hangyu Zhou, Diliyaer Adili, Wei Zhu, Yong Liu, Wenzheng Zhou, Zhao Wang, Jie Li
Article Number: 94
Published online on: 04 February 2026

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Case Report

A novel human papillomavirus‑induced ‘doughnut wart’ lesion treated with 5‑aminolevulinic acid photodynamic therapy: A case report

Ke Li, Yitao Qian, Wenjing Zha, Lei Shi
Article Number: 93
Published online on: 04 February 2026

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Case Report Open Access

Comprehensive diagnosis and individualized treatment of multiple primary lung cancer: A case report

Guoxiong Zeng, Yunyan Zhou, Wang Wan, Biao Deng, Chunyuan Chen, Zhu Liang
Article Number: 92
Published online on: 03 February 2026

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Review Open Access

Pathophysiological mechanisms of fatigue and multidisciplinary management strategies (Review)

Hong Zhou, Wenwen Yu, Jiaming Lei, Runzhi Chang, Yingjia Cheng, Guorui Wang, Li Lin
Article Number: 91
Published online on: 03 February 2026

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Case Report Open Access

A rare upstream regulatory region mutation in APC presenting as classical familial adenomatous polyposis: A case report and literature review

Chi-Han Yang, Yen-Cheng Chen, Tsung-Kun Chang, Wei-Chih Su, Ching-Wen Huang, Hsiang-Lin Tsai, Jaw-Yuan Wang
Article Number: 90
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] lncRNA MIAT promote cell invasion and migration in esophageal cancer

Weiguo Zhang, Qiang Chen, Caipeng Lei
Article Number: 89
Published online on: 02 February 2026

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Review Open Access

Mitochondria‑driven ferroptosis in intervertebral disc degeneration: A novel target in age‑related spinal diseases (Review)

Yang Hou, Xiaolei Yang, Duorun Qiu, Lei Liu, Jiangang Shi, Yongfei Guo
Article Number: 88
Published online on: 02 February 2026

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Case Report

Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report

Jingxian Li, Fang Wang, Yuanshu Du, Yonghui Wang
Article Number: 87
Published online on: 02 February 2026

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Case Report Open Access

Gastric wall thickening and gastric outlet obstruction due to peritoneal metastasis in breast cancer: A case report

Bin He, Lin Ling Li, Ting Yu, Yu Tan, Ling Zhang
Article Number: 86
Published online on: 29 January 2026

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Article Open Access

Myrrh ameliorates endometriosis by enhancing ER stress‑related apoptotic cell death

Bo-Sung Kim, Minkyoung Cho, Jung Ho Han, Jung-Sook Jin, Sung-Jin Bae, Yunju Jo, Dongryeol Ryu, Yerim Joo, Seon Beom Kim, Jongkil Joo, Inhye Kim, Ki-Tae Ha
Article Number: 85
Published online on: 29 January 2026

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