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New diagnostic and therapeutic procedures applied in pediatric esophageal achalasia in a pediatric tertiary center: A case series

  • Authors:
    • Daniela Pop
    • Radu Samuel Pop
    • Teodora Surdea Blaga
    • Liliana David
    • Carmen Asavoaie
    • Marcel Tantau
    • Dan Lucian Dumitrascu
    • Dorin Farcau
  • View Affiliations / Copyright

    Affiliations: Third Pediatric Discipline, Mother and Child Department, ‘Iuliu Hațieganu’ University of Medicine and Pharmacy, 400394 Cluj‑Napoca, Romania, Second Medical Department, ‘Iuliu Hațieganu’ University of Medicine and Pharmacy, 400000 Cluj‑Napoca, Romania, Gastroenterology Department, Second Medical Clinic, Emergency Clinical County Hospital, 400000 Cluj‑Napoca, Romania, Department of Radiology, Clinical Emergency Hospital for Children, 400394 Cluj‑Napoca, Romania, Third Medical Department, ‘Iuliu Hațieganu’ University of Medicine and Pharmacy, 400162 Cluj‑Napoca, Romania, Third Pediatric Department, Clinical Emergency Hospital for Children, 400394 Cluj‑Napoca, Romania
    Copyright: © Pop et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 101
    |
    Published online on: January 17, 2023
       https://doi.org/10.3892/etm.2023.11800
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Abstract

Achalasia is an esophageal motor disorder that is rare in children. While the condition is uncommon, it is especially difficult to diagnose in pediatric patients; however, the ability to form a diagnosis has progressed markedly with the advent of esophageal high‑resolution manometry (HRM). The aim of the present study was to highlight particularities of the diagnosis, based on esophageal HRM, as well as the treatment of achalasia in children. The current study analyzed cases of achalasia from a single pediatric tertiary center, Clinical Emergency Hospital for Children (Cluj‑Napoca, Romania). The clinical data and the results of the investigations of seven children with achalasia, the first children to be evaluated using esophageal HRM in the center, were reported. The patients were aged between 11 and 18 years. All the patients were newly diagnosed with achalasia, except for one. The duration of symptoms was between 4 months and 2 years in the newly diagnosed patients. All the patients were assessed with conventional esophageal manometry and/or esophageal HRM. A multidisciplinary team contributed to the diagnosis and the management of achalasia. A total of 4 children diagnosed with type II achalasia were treated with peroral endoscopic myotomy (POEM) and 3 of the patients were treated with pneumatic dilations. Overall, achalasia is a rare but challenging condition in children. A diagnosis starts with a clinical suspicion based on swallowing disorders and upper digestive endoscopy, and is confirmed by esophageal HRM. Therapy should be adapted to the type of achalasia, the age of the children and the severity. In the present study, a relatively recent treatment option, POEM, was applied in pediatric patients with minor immediate adverse events. The report of these cases adds to the limited experience of using HRM and POEM in children with achalasia.
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Copy and paste a formatted citation
Spandidos Publications style
Pop D, Pop RS, Blaga TS, David L, Asavoaie C, Tantau M, Dumitrascu DL and Farcau D: New diagnostic and therapeutic procedures applied in pediatric esophageal achalasia in a pediatric tertiary center: A case series. Exp Ther Med 25: 101, 2023.
APA
Pop, D., Pop, R.S., Blaga, T.S., David, L., Asavoaie, C., Tantau, M. ... Farcau, D. (2023). New diagnostic and therapeutic procedures applied in pediatric esophageal achalasia in a pediatric tertiary center: A case series. Experimental and Therapeutic Medicine, 25, 101. https://doi.org/10.3892/etm.2023.11800
MLA
Pop, D., Pop, R. S., Blaga, T. S., David, L., Asavoaie, C., Tantau, M., Dumitrascu, D. L., Farcau, D."New diagnostic and therapeutic procedures applied in pediatric esophageal achalasia in a pediatric tertiary center: A case series". Experimental and Therapeutic Medicine 25.3 (2023): 101.
Chicago
Pop, D., Pop, R. S., Blaga, T. S., David, L., Asavoaie, C., Tantau, M., Dumitrascu, D. L., Farcau, D."New diagnostic and therapeutic procedures applied in pediatric esophageal achalasia in a pediatric tertiary center: A case series". Experimental and Therapeutic Medicine 25, no. 3 (2023): 101. https://doi.org/10.3892/etm.2023.11800
Copy and paste a formatted citation
x
Spandidos Publications style
Pop D, Pop RS, Blaga TS, David L, Asavoaie C, Tantau M, Dumitrascu DL and Farcau D: New diagnostic and therapeutic procedures applied in pediatric esophageal achalasia in a pediatric tertiary center: A case series. Exp Ther Med 25: 101, 2023.
APA
Pop, D., Pop, R.S., Blaga, T.S., David, L., Asavoaie, C., Tantau, M. ... Farcau, D. (2023). New diagnostic and therapeutic procedures applied in pediatric esophageal achalasia in a pediatric tertiary center: A case series. Experimental and Therapeutic Medicine, 25, 101. https://doi.org/10.3892/etm.2023.11800
MLA
Pop, D., Pop, R. S., Blaga, T. S., David, L., Asavoaie, C., Tantau, M., Dumitrascu, D. L., Farcau, D."New diagnostic and therapeutic procedures applied in pediatric esophageal achalasia in a pediatric tertiary center: A case series". Experimental and Therapeutic Medicine 25.3 (2023): 101.
Chicago
Pop, D., Pop, R. S., Blaga, T. S., David, L., Asavoaie, C., Tantau, M., Dumitrascu, D. L., Farcau, D."New diagnostic and therapeutic procedures applied in pediatric esophageal achalasia in a pediatric tertiary center: A case series". Experimental and Therapeutic Medicine 25, no. 3 (2023): 101. https://doi.org/10.3892/etm.2023.11800
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