An overview and update of CO<sub>2</sub> laser‑assisted sclerectomy surgery in primary open angle glaucoma (Review)

Huang,Chunlian; Shen,Xiao; Chen,Min; Wang,Kaijun

doi:10.3892/etm.2023.11969

An overview and update of CO₂ laser‑assisted sclerectomy surgery in primary open angle glaucoma (Review)

Authors:
- Chunlian Huang
- Xiao Shen
- Min Chen
- Kaijun Wang
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Affiliations: Department of Ophthalmology, Taizhou Central Hospital, Taizhou University Hospital, Taizhou, Zhejiang 318000, P.R. China, Eye Center of the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310009, P.R. China
Published online on: April 20, 2023 https://doi.org/10.3892/etm.2023.11969
Article Number: 270

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Abstract

Glaucoma is the second leading cause of blindness worldwide. The proportion of cases of primary open‑angle glaucoma (POAG) in China is gradually increasing. Glaucoma surgery has become more effective, safer, minimally invasive and personalized over the years. CO₂ laser‑assisted sclerectomy surgery (CLASS) is a minimally invasive glaucoma treatment. CLASS has recently been used to gradually lower intraocular pressure (IOP) in patients with POAG, pseudocapsular detachment syndrome and secondary glaucoma. In this operation, precise ablation of dry tissue followed by photocoagulation and effective absorption of water and percolating aqueous humor using CO₂ laser are performed, and the IOP is lowered by the laser ablation of the deep sclera and the outer wall of the Schlemm's canal, facilitating the drainage of the aqueous humor. Compared with other filtering surgeries, CLASS has a shorter learning curve, lower technical difficulty and higher safety. The present study reviews the clinical application progress, safety and effectiveness of CLASS.

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