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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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June-2023 Volume 25 Issue 6

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Article Open Access

Titanium‑coated polyetheretherketone cages vs. polyetheretherketone cages in lumbar interbody fusion: A systematic review and meta‑analysis

Songfeng Li, Xiyong Li, Xiaohui Bai, Yunlu Wang, Pengfei Han, Hongzhuo Li
Article Number: 305
Published online on: 09 May 2023

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Article Open Access

Role of the TPX2/NCOA5 axis in regulating proliferation, migration, invasion and angiogenesis of breast cancer cells

Tian Wang, Fulin Zhang, Peirong Zhang
Article Number: 304
Published online on: 09 May 2023

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Article Open Access

CKLF1 interference alleviates IL‑1β‑induced inflammation, apoptosis and degradation of the extracellular matrix in chondrocytes via CCR5

Haoran Wang, Zhongqing Wu, Kanna Xu
Article Number: 303
Published online on: 09 May 2023

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Article Open Access

Roflumilast reduces myocardial ischemia reperfusion injury in vivo and in vitro by activating the AMPK signaling pathway

Bo Liao, Zhongyuan Han
Article Number: 302
Published online on: 09 May 2023

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Article Open Access

High‑dose aflibercept injection has striking effects on myopic choroidal neovascularization

Wei Zhu, Yanlei Hao, Zhongfang Yuan, Chunmei Huang
Article Number: 301
Published online on: 09 May 2023

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Review Open Access

Proanthocyanidins: A novel approach to Henoch‑Schonlein purpura through balancing immunity and arresting oxidative stress via TLR4/MyD88/NF‑κB signaling pathway (Review)

Yuxin Xie, Qiyan Deng, Menglu Guo, Xiaolong Li, Deihai Xian, Jianqiao Zhong
Article Number: 300
Published online on: 09 May 2023

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Article Open Access

Age‑adjusted Charlson comorbidity index and in‑hospital mortality in critically ill patients with cardiogenic shock: A retrospective cohort study

Dongmei Wei, Yang Sun, Rongtao Chen, Yuanting Meng, Wei Wu
Article Number: 299
Published online on: 05 May 2023

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Article Open Access

Efficacy and safety of vedolizumab in the treatment of patients with inflammatory bowel disease: A systematic review and meta‑analysis of randomized controlled trials

Hui-Jun Tang, Cai-Qun Bie, Li-Liangzi Guo, Li-Xian Zhong, Shao-Hui Tang
Article Number: 298
Published online on: 05 May 2023

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Article Open Access

Efficacy and safety of covered versus uncovered self‑expandable metal stents for the palliative treatment of malignant distal biliary stricture: A long‑term retrospective study

Liang Zhu, Zhenwen Wang, Zhiquan Huang, Xueping Yang, Zhengping Yu, Ronglai Cao, Youxiang Chen
Article Number: 297
Published online on: 05 May 2023

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Article Open Access

An updated systematic review and meta‑analysis comparing deltoid‑split approach with deltopectoral approach for proximal humerus fractures

Zhe Wu, Wenting Shen
Article Number: 296
Published online on: 05 May 2023

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Article Open Access

Oxidation‑reduction potential parameters worsen following intraarterial therapy in patients with reduced collateral circulation and middle cerebral artery occlusions

Benjamin Atchie, Stephanie Jarvis, Richard Bellon, Trevor Barton, Lauren Disalvo, Kristin Salottolo, Raphael Bar-Or, David Bar-Or
Article Number: 295
Published online on: 05 May 2023

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Article Open Access

miR‑424‑5p is downregulated in the placentas of patients with preeclampsia and affects trophoblast migration and invasion

Weimin Zhu, Xing Chen
Article Number: 294
Published online on: 05 May 2023

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Article Open Access

Outcomes in meningitis‑ventriculitis treated with intravenous or intrathecal plus intravenous colistin: A meta‑analysis

Vasiliki Epameinondas Georgakopoulou, Demetrios A. Spandidos, Petros Papalexis, Aikaterini Gkoufa, Aikaterini Aravantinou‑Fatorou, Efthalia Angelopoulou, Ilias Trakas, Nikolaos Trakas, George Fotakopoulos
Article Number: 293
Published online on: 04 May 2023

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Article Open Access

A combination of Sophora flavescens alkaloids and Panax quinquefolium saponins attenuates coxsackievirus B3‑induced acute myocarditis in mice via NF‑κB signaling

Menghui Liu, Meiling Fan, Huibo Xu, Bo Liu, Xin Wang, Fuchun Wen, Fenglan Ji, Tao Ding
Article Number: 292
Published online on: 04 May 2023

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Review Open Access

COVID‑19 vaccination in liver transplant recipients (Review)

Aikaterini Gkoufa, Maria Saridaki, Vasiliki Epameinondas Georgakopoulou, Demetrios A. Spandidos, Evangelos Cholongitas
Article Number: 291
Published online on: 03 May 2023

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Article Open Access

Effects of norepinephrine‑induced activation of rat vascular adventitial fibroblasts on proliferation and migration of BMSCs involved in vascular remodeling

Jun Gao, Li Li, Dongli Zhou, Xuhong Sun, Lilu Cui, Donglin Yang, Xiaohui Wang, Pengchao Du, Wendan Yuan
Article Number: 290
Published online on: 03 May 2023

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Article Open Access

IL‑37 suppresses macrophage ferroptosis to attenuate diabetic atherosclerosis via the NRF2 pathway

Jinmei Xu, Xu Han, Nan Xia, Qingsong Zhao, Zhifeng Cheng
Article Number: 289
Published online on: 03 May 2023

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Article Open Access

Profile analysis of differentially expressed long non‑coding RNAs in metabolic memory induced by high glucose in human umbilical vein endothelial cells

Jingya Cheng, Anqi Huang, Ji Cheng, Xiaoyan Pei, Lei Yu, Guoxi Jin, Erqin Xu
Article Number: 288
Published online on: 02 May 2023

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Article Open Access

Novel SCN5A frame‑shift mutation underlying in patient with idiopathic ventricular fibrillation manifested with J wave in inferior lead and prolonged S‑wave in precordial lead

Xiaoqian Zhou, Lan Ren, Jian Huang, Yinhui Zhang, Ying Cai, Jielin Pu
Article Number: 287
Published online on: 02 May 2023

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Article Open Access

Effect of dexmedetomidine on preventing perioperative respiratory adverse events in children: A systematic review and meta‑analysis of randomized controlled trials

Junli Zhang, Jing Yin, Yuanyuan Li, Yu Zhang, Yaowu Bai, Hongyuan Yang
Article Number: 286
Published online on: 28 April 2023

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Case Report Open Access

Multilocular thymic cyst detected during COVID‑19 treatment in an HIV‑positive adult man: A case report and literature review

Hiroto Hatano, Ryusuke Sumiya, Kento Misumi, Hideki Miyazaki, Takeshi Ikeda, Satoshi Nagasaka
Article Number: 285
Published online on: 28 April 2023

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Case Report Open Access

Ultrasound diagnosis of a retroperitoneal fetus in fetu: A case report

Wentong Peng, Shaoqin Zeng, Mei Dong
Article Number: 284
Published online on: 27 April 2023

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Case Report

Malignant behavior of a well‑differentiated digestive neuroendocrine tumor with peritoneal carcinomatosis: A case report

Klara Wyffels, Charlotte De Wilde, Jacques Van Huysse, Vincent De Wilde
Article Number: 283
Published online on: 26 April 2023

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Article Open Access

Expression of S100A9 in adamantinomatous craniopharyngioma and its association with wet keratin formation

Chuan Zhao, Wenxin Hu, Ning Luo, Xingfu Wang, Da Lin, Zhixiong Lin
Article Number: 282
Published online on: 26 April 2023

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Article Open Access

Intermittent physical recovery has similar benefits to continuous physical recovery in patients in the acute and early sub‑acute stages following a stroke

Alexandra Maria Poenaru, George Cioroianu, Adrian Tudor Balseanu, Simona Covei Banicioiu, Otilia Constantina Rogoveanu
Article Number: 281
Published online on: 25 April 2023

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Article Open Access

Clinical value of anterior segment optical coherence tomography‑assisted Wuerzburg bleb classification system for bleb assessment following trabeculectomy

Yi Sun, Jing Zhu, Juan Guo, Yuanxu He, Zhanfeng Wang
Article Number: 280
Published online on: 25 April 2023

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Review Open Access

Clinicopathological characteristics, molecular features and novel diagnostic strategies for the detection of malignant transformation of endometriosis (Review)

Hiroshi Kobayashi
Article Number: 279
Published online on: 24 April 2023

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Article Open Access

Study of dietary‑induced progression of psoriasis‑like mice based on gut macrophage polarization

Wucheng Zeng, Yihan Wang, Yi Cao, Fengling Xing, Xiaohong Yang
Article Number: 278
Published online on: 24 April 2023

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Article Open Access

SPTBN2 regulates endometroid ovarian cancer cell proliferation, invasion and migration via ITGB4‑mediated focal adhesion and ECM receptor signalling pathway

La Yang, Yuanyuan Gu
Article Number: 277
Published online on: 24 April 2023

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Article Open Access

ZBTB16 eases lipopolysaccharide‑elicited inflammation, apoptosis and degradation of extracellular matrix in chondrocytes during osteoarthritis by suppressing GRK2 transcription

Bo Xiong, Lihua Chen, Yue Huang, Guanyu Lu, Cai Chen, Jiao Nong, Haida Pan
Article Number: 276
Published online on: 24 April 2023

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Review Open Access

New insights on IL‑36 in intestinal inflammation and colorectal cancer (Review)

Minghui Li, Wei Jiang, Zehui Wang, Yihan Lu, Jun Zhang
Article Number: 275
Published online on: 21 April 2023

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Article Open Access

SETDB1 induces lenalidomide resistance in multiple myeloma cells via epithelial‑mesenchymal transition and PI3K/AKT pathway activation

Xiaoli Qian, Yang Yang, Yingfen Deng, Yali Liu, Yuwen Zhou, Fang Han, Yue Xu, Hongjian Yuan
Article Number: 274
Published online on: 21 April 2023

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Article Open Access

Efficacy and safety of proton pump inhibitors and H2 receptor antagonists in the initial non‑eradication treatment of duodenal ulcer: A network meta‑analysis

Xiangbo Meng, Xiuying Zhu, Baixue Li, Jibin Liu, Jiawei Zhao, Hua Wang, Quansheng Feng, Yue Su
Article Number: 273
Published online on: 21 April 2023

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Article Open Access

CD73 blockade alleviates intestinal inflammatory responses by regulating macrophage differentiation in ulcerative colitis

Ru Wang, Yan Wang, Chao Wu, Guiyuan Jin, Fengqin Zhu, Yonghong Yang, Yibo Wang, Guangxi Zhou
Article Number: 272
Published online on: 21 April 2023

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Article Open Access

Changes in the balance of Th17/Treg cells and oxidative stress markers in patients with HIV‑associated pulmonary tuberculosis who develop IRIS

Long Wen, Lei Shi, Shan-Shan Wan, Tao Xu, Lei Zhang, Zhi-Guo Zhou
Article Number: 271
Published online on: 21 April 2023

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Review

An overview and update of CO2 laser‑assisted sclerectomy surgery in primary open angle glaucoma (Review)

Chunlian Huang, Xiao Shen, Min Chen, Kaijun Wang
Article Number: 270
Published online on: 20 April 2023

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Case Report Open Access

Multicentric Castleman disease of hyaline‑vascular variant with paraneoplastic pemphigus results in abnormal lung function: Report of 3 cases

Jiemei Cen, Wen Zeng, Mianluan Pan, Ye Qiu, Jianquan Zhang
Article Number: 269
Published online on: 20 April 2023

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Review Open Access

Autophagy in the pharmacological activities of celastrol (Review)

Caixia Zhang, Weiyan Wang, Chenhui Du, Huifang Li, Kun Zhou, Zhihua Luan, Yinxia Chang, Shan Liu, Yanming Wei
Article Number: 268
Published online on: 20 April 2023

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Article Open Access

Sequencing and bioinformatics analysis of miRNA from rat endplate chondrogenic exosomes

Xue-Wu Chen, Qiu-Wei Li, Hong Wang
Article Number: 267
Published online on: 20 April 2023

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Article Open Access

Clinical analysis of tumescent anesthesia technique combined with superficial fascia rotational atherectomy in axillary bromhidrosis

Yong-Ping Shi, Ju-Hong Li, Yu Wang, Yanfei Wu
Article Number: 266
Published online on: 20 April 2023

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Article Open Access

Sulforaphane alleviates lung ischemia‑reperfusion injury through activating Nrf‑2/HO‑1 signaling

Liang Zhang, Shuxian Wang, Ying Zhang, Fenghuan Li, Chaoxiao Yu
Article Number: 265
Published online on: 20 April 2023

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Article Open Access

PRMT5 inhibition ameliorates inflammation and promotes the osteogenic differentiation of LPS‑induced periodontal stem cells via STAT3/NF‑κB signaling

Kun Zhang, Changshun Li, Jian Sun, Xiaobei Tian
Article Number: 264
Published online on: 19 April 2023

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Article Open Access

Evaluation of clinical efficacy of tumor necrosis factor‑α inhibitors in treatment of distal extremity swelling with pitting edema in psoriatic arthritis of inadequate response to conventional therapy: A 10‑year retrospective study

Chenyang Zhao, Bingqian Liu, Yuan Yao, Kevin Yang, Bo Zang, Bin Liu
Article Number: 263
Published online on: 19 April 2023

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Case Report Open Access

Appendiceal perforation secondary to endometriosis with intestinal metaplasia: A case report

Minghua Wang, Jing Liu, Boxin Hu, Simin Wang, Ping Xie, Ping Li
Article Number: 262
Published online on: 19 April 2023

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Article Open Access

Axons of retinal ganglion cells on the optic nerve disc following vessel density correction at different IOP values

Ján Lešták, Martin Fůs, Jakub Král
Article Number: 261
Published online on: 19 April 2023

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Article Open Access

ADAM metallopeptidase domain 10 knockdown enables podocytes to resist high glucose stimulation by inhibiting pyroptosis via MAPK pathway

Chunjie Sui, Dan Zhou
Article Number: 260
Published online on: 18 April 2023

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Article Open Access

Diosgenin alleviates the inflammatory damage and insulin resistance in high glucose‑induced podocyte cells via the AMPK/SIRT1/NF‑κB signaling pathway

Haoyu Yuan, Huacheng Sui, Saimei Li
Article Number: 259
Published online on: 18 April 2023

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Case Report Open Access

Growth restriction and congenital heart disease caused by a novel TAB2 mutation: A case report

Qian Deng, Xin Wang, Jian Gao, Xiaowei Xia, Yungong Wang, Yin Zhang, Yuqing Chen
Article Number: 258
Published online on: 18 April 2023

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Case Report

Laparoscopy and ureteroscopy cooperative surgery for high burden stones in solitary kidney and ureter in one stage: A case report

Kejia Zhu, Yao Chang, Delong Zhao, Yong Guan, Sentai Ding
Article Number: 257
Published online on: 18 April 2023

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Article

A biomechanical analysis of the effect of hydroxyapatite augmentation for trochanteric femoral fractures

Takuya Usami, Naoya Takada, Hidetoshi Iwata, Hiroaki Sakai, Yusuke Hattori, Isato Sekiya, Yoshino Ueki, Yuko Nagaya, Hideki Murakami, Gen Kuroyanagi
Article Number: 256
Published online on: 18 April 2023

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Article Open Access

Estrogen alleviates acute and chronic itch in mice

Jinhua Jin, Li Li, Yuhui Wang, Keyan Li, Aihua Qian, Weiou Li, Qing Liu, Chao Wen, Quanle Liu, Guanghai Yan, Fushan Xue
Article Number: 255
Published online on: 18 April 2023

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Article Open Access

COVID-19 association with multidrug-resistant bacteria superinfections: Lessons for future challenges

Monica Susan, Razvan Susan, Viorica Lazar, Iulia-Cristina Bagiu, Alin Gabriel Mihu, Radu Vasile Bagiu, Alin Ionescu, Andreea Narcisa Iana, Cristina Adriana Dehelean, Daniel Lighezan, Daniela Teodora Marti
Article Number: 254
Published online on: 18 April 2023

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Article Open Access

Decreased SPTBN2 expression regulated by the ceRNA network is associated with poor prognosis and immune infiltration in low‑grade glioma

Guo-Rong Chen, Yi-Bin Zhang, Shu-Fa Zheng, Ya-Wen Xu, Peng Lin, Huang-Cheng Shang‑Guan, Yuan-Xiang Lin, De-Zhi Kang, Pei-Sen Yao
Article Number: 253
Published online on: 18 April 2023

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Article

Endovascular and open repair of visceral aneurysms: A retrospective single‑center analysis

Artur Rebelo, Ulrich Ronellenfitsch, Jumber Partsakhaschwilli, Jörg Kleeff, Endres John, Jörg Ukkat
Article Number: 252
Published online on: 18 April 2023

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Article Open Access

INSR and ISR‑1 gene polymorphisms and the susceptibility of essential hypertension: A meta‑analysis

Yan Wang, Jianming Li, Qin Xiang, Liang Tang
Article Number: 251
Published online on: 13 April 2023

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Case Report Open Access

Extracorporeal membrane oxygenation combined with minimally invasive surgery for acute respiratory failure and sudden cardiac arrest: A case report

Da-Wei Guo, Jun Gao, Heng-Lan Wu, Cheng Wu, Jian-Xiang Wu, Qiang Rui, Yi Bao, Zhong-Hua Liu, Xi-Yong Wang, Li-Dong Xu, Xun Hu, Jun Zhang
Article Number: 250
Published online on: 13 April 2023

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Article Open Access

Effect of liraglutide on atherosclerosis in patients with impaired glucose tolerance: A double‑blind, randomized controlled clinical trial

Liping Sun, Yuhong Yuan, Yongmei Li, Xiaopang Rao
Article Number: 249
Published online on: 13 April 2023

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Article Open Access

Role of p53 in promoting BMP9‑induced osteogenic differentiation of mesenchymal stem cells through TGF‑β1

Xintong Yao, Peipei Li, Yixuan Deng, Yuanyuan Yang, Honghong Luo, Baicheng He
Article Number: 248
Published online on: 13 April 2023

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Article Open Access

Knockdown of KAT5/KIF11 induces autophagy and promotes apoptosis in anaplastic thyroid cancer cells

Lei Fu, Lina Zhao, Chunyan Liao, Pengzhen Wang, Ying Gu, Sha Li, Liying Shi, Qiaorong Wang, Jin Xie, Lixin Zhang, Xiaoming Liu, Bei Zhang
Article Number: 247
Published online on: 12 April 2023

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Article

Acrylamide induces human chondrocyte cell death by initiating autophagy‑dependent ferroptosis

Hui Wang, Zizheng Tang, Shasha Liu, Kangqi Xie, Hua Zhang
Article Number: 246
Published online on: 12 April 2023

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Article

Targeted RASSF1A expression inhibits proliferation of HER2‑positive breast cancer cells in vitro

Sai He, Yanni Hou, Leina Hou, Nan Chen, Xiaomin Yang, Huxia Wang, Pihua Han, Yongguo Fan, Jing Zhao, Jingyuan Zhang, Jie Geng
Article Number: 245
Published online on: 11 April 2023

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Article

Polymorphisms in microRNA binding site of SET8 regulate the risk of rheumatoid arthritis

Chenxing Peng, Yufei Zhao, Xiaoyun Zhang, Jingjing Zhang, Ziyue Sha, Shasha Zhang
Article Number: 244
Published online on: 11 April 2023

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Article Open Access

Alisertib exerts KRAS allele‑specific anticancer effects on colorectal cancer cell lines

Baojun Ren, Yan Geng, Shuxiang Chen, Zhuowei Gao, Kehong Zheng, Yong Yang, Qimei Luo, Jing Feng, Zhentao Luo, Yongle Ju, Zonghai Huang
Article Number: 243
Published online on: 11 April 2023

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Article Open Access

Downregulation of microRNA‑494 inhibits cell proliferation in lung squamous cell carcinoma via the induction of PUMA‑α‑mediated apoptosis

Xinyuan Gao, Xiaohua Yang, Fengzhen He, Xue Liu, Ding Liu, Xiaomei Yuan
Article Number: 242
Published online on: 11 April 2023

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Article Open Access

Alleviating effect of lycorine on CFA‑induced arthritic pain via inhibition of spinal inflammation and oxidative stress

Yin-Di Hu, Yuan-Fen Yue, Tao Chen, Zhao-Di Wang, Jie-Qing Ding, Min Xie, Dai Li, Hai-Li Zhu, Meng-Lin Cheng
Article Number: 241
Published online on: 11 April 2023

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March-2026 Volume 31 Issue 3

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Impact Factor: 2.3

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Effect of SGLT2 inhibitors on heart failure outcomes in patients with and without diabetes: A systematic review and meta‑analysis of randomized controlled trials

Duaa Abdullah Bafail, Noura Hamdi Alhalees
Article Number: 84
Published online on: 28 January 2026

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Exploring the protective mechanisms and therapeutic potential of carnosic acid against acute respiratory distress syndrome through molecular docking, molecular dynamics and experimental verification

Quan Li, Lili Ding, Haijun Sun, Weichao Ding, Mengmeng Wang, Zhaorui Sun, Congxue Ma
Article Number: 83
Published online on: 28 January 2026

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Review

Exploring the roots of schizophrenia: Current research and future directions (Review)

Shuang Lv, Chunxia Luo
Article Number: 82
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] miR‑146a‑5p protects against renal injury in MRL/lpr mice via improvement of the Treg/Th17 imbalance by targeting the TRAF6/NF‑κB axis

Jiajia Teng, Feng Yang, Xiaoling Li
Article Number: 81
Published online on: 28 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑24‑3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl‑2‑like protein 11

Huanxin Zhang, Shizhen Xue, Yi Feng, Jun Shen, Jixian Zhao
Article Number: 80
Published online on: 26 January 2026

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Efficacy and safety of unilateral biportal endoscopy vs. percutaneous endoscopic interlaminar approach in lumbar disc herniation: A meta‑analysis​

Yuhao Gao, Fangzheng He, Ji Wen, Shilei Qin, Pengfei Han, Yunfeng Xu
Article Number: 79
Published online on: 23 January 2026

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Case Report Open Access

Intralobar pulmonary sequestration coexisting with pulmonary cryptococcosis: A case report and literature review

Dan Cheng, Yue Wang, Jun Li, Dan Yu, Yunyun Wang, Jinbo Fan, Jiankun Wang, Liqun He
Article Number: 78
Published online on: 23 January 2026

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Tumor‑associated macrophages suppress estrogen receptor‑β expression in triple‑negative breast cancer through the PI3K/AKT pathway

Qiulei Zhang, Di Guo, Gaoran Xu, Rong Xie, Yuqing Deng, Peng Fu, Jinnan Wan
Article Number: 77
Published online on: 21 January 2026

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Development of a diagnostic model for esophageal achalasia assessed by esophageal high‑resolution manometry using artificial intelligence

Maiko Tabuchi, Yasuhiko Nakao, Hitomi Minami, Hiroko Inomata, Junya Shiota, Taro Akashi, Keiichi Hashiguchi, Moto Kitayama, Kayoko Matsushima, Naoyuki Yamaguchi, Yuko Akazawa, Hisamitsu Miyaaki
Article Number: 76
Published online on: 21 January 2026

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Case Report

Use of metagenomic next‑generation sequencing to diagnose Tropheryma whipplei infection‑related pneumonia: A case report

Yutu Luo, Haibing Ding, Jiahua Pan, Guangyang Xu
Article Number: 75
Published online on: 21 January 2026

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Effect of rivaroxaban on DNA damage in an ischemia-reperfusion model: Evaluation of 8‑OHdG levels

Ceren Sayarer, Abidin Cenk Erdal, Tuğra Gençpinar, Özlem Gürsoy Doruk, Tuncay Küme
Article Number: 74
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Hepatoprotective activity of chrysin is mediated through TNF‑α in chemically‑induced acute liver damage: An in vivo study and molecular modeling 

Anca Hermenean, Teodora Mariasiu, Inmaculada Navarro-González, Josefina Vegara-Meseguer, Eftimie Miuțescu, Sandipan Chakraborty, Horacio Pérez-Sánchez
Article Number: 73
Published online on: 21 January 2026

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Retraction Open Access

[Retracted] Gambogic acid suppresses colon cancer cell activity in vitro

Zailong Zhou, Jian Ma
Article Number: 72
Published online on: 19 January 2026

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Case Report

Identification of a novel KISS1R (GPR54) gene variant (c.505+2T>G) in a patient with congenital hypogonadotropic hypogonadism: A case report and literature review

Burak Menekse, Enes Ucgul, Abdullatif Bakir, Sema Hepsen, Ilknur Ozturk Unsal, Muhammed Kizilgul, Takako Araki, Erman Cakal
Article Number: 71
Published online on: 16 January 2026

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Postoperative hypofractionated intensity-modulated proton therapy to control recurrent paraganglioma at the jugular foramen: A case report and literature review

Wei Wang, Yingxia Yuan, Jiwei Bai, Yue Zou, Dongxue Zhou, Jun Zhao, Shuyan Zhang, Zishen Wang, Jie Wang, Jingjing Kong, Lu Yang, Masashi Mizumoto, Hideyuki Sakurai, Shosei Shimizu
Article Number: 70
Published online on: 16 January 2026

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Article

Serum antithrombin III level predicts acute kidney injury in patients with traumatic brain injury

Ruoran Wang, Min He, Jianguo Xu
Article Number: 69
Published online on: 16 January 2026

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Retraction Open Access

[Retracted] β‑asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal‑regulated kinase signaling pathway

Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong Li
Article Number: 68
Published online on: 12 January 2026

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Case Report Open Access

Rare co‑occurrence of gastrointestinal stromal tumors and leiomyomas: A case report and review of the literature

Yu Zhang, Xiaoqiong Shi, Wenfu Xie, Meilin He, Shan Zhang, Xue Peng, Hao Lei, Xulei Li, Haiying Liu, Qiao Shu, Fangyuan Zou, Mingyong Wei
Article Number: 67
Published online on: 09 January 2026

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No increased risk of hepatic enzyme abnormalities with non‑peptidic thrombopoietin receptor agonists in immune thrombocytopenia: A meta‑analysis of randomized controlled trials

Nan Shen, Rang Wu, Tiantian Lu, Song Liu, Yazhou Jiang, Jingjing Yan, Tao Ning, Chang Dong, Jianqin Li, Suyue Zhu
Article Number: 66
Published online on: 09 January 2026

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Case Report

Submucosal colonic fecalith mimicking a submucosal malignant tumor at the anastomotic site after colon cancer: A case report

Motoaki Yuhi, Masatsugu Hiraki, Shin Takesue, Mariko Hashiguchi, Megumi Nishiyama, Yoshiaki Egashira, Tatsuya Manabe, Hirokazu Noshiro
Article Number: 65
Published online on: 08 January 2026

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Clinical characteristics of acute primary angle closure following COVID‑19 during the Omicron outbreak in China

Jianhui Zhang, Yingying Xue, Liu Zhang, Yuhong Wang, Shancheng Si
Article Number: 64
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Aberrant expression and mechanism of miR‑130b‑3p/phosphatase and tensin homolog in nephroblastoma in children

Yifeng Hu, Jingtie Yan
Article Number: 63
Published online on: 05 January 2026

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Case Report Open Access

Novel variants in STAG2 and PKD1 associate with multiple congenital malformations and autosomal dominant polycystic kidney disease in a Chinese family: A case report and literature review

Qi Yang, Qiang Zhang, Sheng Yi, Xunzhao Zhou, Yiyan Ruan, Shujie Zhang, Shang Yi, Qinle Zhang, Zailng Qin, Jingsi Luo
Article Number: 62
Published online on: 30 December 2025

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April-2026 Volume 31 Issue 4

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Impact Factor: 2.3

Case Report

Sagittal sinus thrombosis in pregnancy: A case report

Zaheera Saadia, Misbah Ilyas, Jayd Saud Althwiny, Fai Alaqel, Alanoud Abdullah Alsufayri, Lujain Husain Almutairi
Article Number: 100
Published online on: 05 February 2026

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Article

Elevated PGE2 and COX‑2 expression in villous adenoma: Implications for electrolyte depletion syndrome

Shiki Fujino, Hiroyuki Fukuda, Katsuki Danno, Takashi Takeda, Masaya Higashiguchi, Kozo Noguchi, Takefumi Hirao, Aya Ito, Norikatsu Miyoshi, Yoshio Oka
Article Number: 99
Published online on: 04 February 2026

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Wogonin as a potential therapeutic agent for psoriasis: Core target identification and validation

Yu Lu, Xiaomei Zhou, Yiyu Guo, Fengrui Zhang, Jirong Wang, Jinhong Ge, Yan Xiao, Dengke Yang
Article Number: 98
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Glibenclamide exacerbates adriamycin‑induced cardiotoxicity by activating oxidative stress‑induced endoplasmic reticulum stress in rats

Meng-Lin Liu, Meng-Long Wang, Jing-Jun Lv, Jie Wei, Jun Wan
Article Number: 97
Published online on: 04 February 2026

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Review

Key role of the autonomic nervous system in breast cancer (Review)

Min Wu, Zhiwu Zhang, Lu Zhou, Shiqi Liu, Qing Chen, Cui Guo, Shasha Zhao, Xuedan Chen
Article Number: 96
Published online on: 04 February 2026

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Senescent hepatic stellate cells drive inflammation and disease progression in MASH (Review)

Zhiqi Han, Yiran She, Di Wu, Nuo Zhang, Zheyuan Liu, Zhongyuan Wang, Xiaoying Zhou, Shuo Li
Article Number: 95
Published online on: 04 February 2026

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PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells

Zilong Zhang, Hangyu Zhou, Diliyaer Adili, Wei Zhu, Yong Liu, Wenzheng Zhou, Zhao Wang, Jie Li
Article Number: 94
Published online on: 04 February 2026

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Case Report

A novel human papillomavirus‑induced ‘doughnut wart’ lesion treated with 5‑aminolevulinic acid photodynamic therapy: A case report

Ke Li, Yitao Qian, Wenjing Zha, Lei Shi
Article Number: 93
Published online on: 04 February 2026

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Comprehensive diagnosis and individualized treatment of multiple primary lung cancer: A case report

Guoxiong Zeng, Yunyan Zhou, Wang Wan, Biao Deng, Chunyuan Chen, Zhu Liang
Article Number: 92
Published online on: 03 February 2026

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Pathophysiological mechanisms of fatigue and multidisciplinary management strategies (Review)

Hong Zhou, Wenwen Yu, Jiaming Lei, Runzhi Chang, Yingjia Cheng, Guorui Wang, Li Lin
Article Number: 91
Published online on: 03 February 2026

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Case Report Open Access

A rare upstream regulatory region mutation in APC presenting as classical familial adenomatous polyposis: A case report and literature review

Chi-Han Yang, Yen-Cheng Chen, Tsung-Kun Chang, Wei-Chih Su, Ching-Wen Huang, Hsiang-Lin Tsai, Jaw-Yuan Wang
Article Number: 90
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] lncRNA MIAT promote cell invasion and migration in esophageal cancer

Weiguo Zhang, Qiang Chen, Caipeng Lei
Article Number: 89
Published online on: 02 February 2026

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Review Open Access

Mitochondria‑driven ferroptosis in intervertebral disc degeneration: A novel target in age‑related spinal diseases (Review)

Yang Hou, Xiaolei Yang, Duorun Qiu, Lei Liu, Jiangang Shi, Yongfei Guo
Article Number: 88
Published online on: 02 February 2026

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Case Report

Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report

Jingxian Li, Fang Wang, Yuanshu Du, Yonghui Wang
Article Number: 87
Published online on: 02 February 2026

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Case Report Open Access

Gastric wall thickening and gastric outlet obstruction due to peritoneal metastasis in breast cancer: A case report

Bin He, Lin Ling Li, Ting Yu, Yu Tan, Ling Zhang
Article Number: 86
Published online on: 29 January 2026

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Article Open Access

Myrrh ameliorates endometriosis by enhancing ER stress‑related apoptotic cell death

Bo-Sung Kim, Minkyoung Cho, Jung Ho Han, Jung-Sook Jin, Sung-Jin Bae, Yunju Jo, Dongryeol Ryu, Yerim Joo, Seon Beom Kim, Jongkil Joo, Inhye Kim, Ki-Tae Ha
Article Number: 85
Published online on: 29 January 2026

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