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Early 3‑day course of remdesivir for the prevention of the progression to severe COVID‑19 in the elderly: A single‑centre, real‑life cohort study

  • Authors:
    • Vasiliki Epameinondas Georgakopoulou
    • Aikaterini Gkoufa
    • Sotiria Makrodimitri
    • Dimitrios Basoulis
    • Aristeidis Tsakanikas
    • Georgios Karamanakos
    • Elpida Mastrogianni
    • Pantazis M. Voutsinas
    • Demetrios A. Spandidos
    • Chrysovalantis V. Papageorgiou
    • Maria N. Gamaletsou
    • Nikolaos V. Sipsas
  • View Affiliations / Copyright

    Affiliations: Department of Infectious Diseases and COVID‑19 Unit, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece, Emergency Department, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece, Department of Pathophysiology, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece, Laboratory of Clinical Virology, School of Medicine, University of Crete, 71003 Heraklion, Greece
    Copyright: © Georgakopoulou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 462
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    Published online on: August 9, 2023
       https://doi.org/10.3892/etm.2023.12161
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Abstract

Remdesivir, a viral RNA polymerase inhibitor, has constituted a key component of therapeutic regimens against the pandemic caused by severe acute respiratory syndrome coronavirus‑2 (SARS‑CoV‑2). Originally approved for administration in hospitalized patients, remdesivir leads to improved outcomes in patients with moderate to severe coronavirus disease 2019 (COVID‑19). After proving to be effective in hospitalized patients, its use gained approval in early‑stage disease for symptomatic outpatients who are at a high risk of progression to severe disease. The present study is a real‑life prospective cohort study involving 143 elderly non‑hospitalized patients with SARS‑CoV‑2 (≥65 years of age) who attended the emergency department of the authors' hospital seeking care for COVID‑19 symptoms appearing within the prior 7 days. Eligible patients received intravenous remdesivir at a dose of 200 mg on the first day and 100 mg on days 2 and 3. The efficacy endpoints were set as the need for COVID‑19‑related hospitalization and all‑cause mortality in the following 28 days. A total of 143 patients participated in the study. Of these patients, 118 (82.5%) patients were vaccinated with at least two doses. All patients enrolled completed the 3‑day course, with a total of 6 out of 143 patients (4.2%) having a COVID‑19‑related hospitalization by day 28, and 5 patients (3.5%) succumbing to the disease within the study period. In the univariate Cox regression analysis, the neutrophil‑to‑lymphocyte ratio and haematological malignancy were identified as predictors of progression to severe disease, and albumin levels, the C‑reactive protein‑to‑albumin ratio (CAR) and haematological malignancy were identified as predictors of 28‑day mortality. On the whole, the findings of the present study demonstrated that among the elderly outpatients, a 3‑day course of intravenous remdesivir was associated with favourable outcomes.
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1 

Manciulli T, Spinicci M, Rossetti B, Antonello RM, Lagi F, Barbiero A, Chechi F, Formica G, Francalanci E, Alesi M, et al: Safety and efficacy of outpatient treatments for COVID-19: Real-life data from a regionwide cohort of high-risk patients in Tuscany, Italy (the FEDERATE cohort). Viruses. 15(438)2023.PubMed/NCBI View Article : Google Scholar

2 

Bhimraj A, Morgan RL, Shumaker AH, Baden L, Cheng VCC, Edwards KM, Gallagher JC, Gandhi RT, Muller WJ, Nakamura MM, et al: Infectious diseases society of America guidelines on the treatment and management of patients with COVID-19. Clin Infect Dis: Apr 27, 2020 (Epub ahead of print).

3 

Terkes V, Lisica K, Marusic M, Verunica N, Tolic A and Morovic M: Remdesivir treatment in moderately Ill COVID-19 patients: A retrospective single center study. J Clin Med. 11(5066)2022.PubMed/NCBI View Article : Google Scholar

4 

Frediansyah A, Nainu F, Dhama K, Mudatsir M and Harapan H: Remdesivir and its antiviral activity against COVID-19: A systematic review. Clin Epidemiol Glob Health. 9:123–127. 2021.PubMed/NCBI View Article : Google Scholar

5 

Liang C, Tian L, Liu Y, Hui N, Qiao G, Li H, Shi Z, Tang Y, Zhang D, Xie X and Zhao X: A promising antiviral candidate drug for the COVID-19 pandemic: A mini-review of remdesivir. Eur J Med Chem. 201(112527)2020.PubMed/NCBI View Article : Google Scholar

6 

Beigel JH, Tomashek KM, Dodd LE, Mehta AK, Zingman BS, Kalil AC, Hohmann E, Chu HY, Luetkemeyer A, Kline S, et al: Remdesivir for the treatment of covid-19-final report. N Engl J Med. 383:1813–1826. 2020.PubMed/NCBI View Article : Google Scholar

7 

Goldman JD, Lye DCB, Hui DS, Marks KM, Bruno R, Montejano R, Spinner CD, Galli M, Ahn MY, Nahass RG, et al: Remdesivir for 5 or 10 days in patients with severe covid-19. N Engl J Med. 383:1827–1837. 2020.PubMed/NCBI View Article : Google Scholar

8 

Angamo MT, Mohammed MA and Peterson GM: Efficacy and safety of remdesivir in hospitalised COVID-19 patients: a systematic review and meta-analysis. Infection. 50:27–41. 2022.PubMed/NCBI View Article : Google Scholar

9 

Georgakopoulou VE, Papalexis P, Sanos C, Bitsani A, Garmpi A, Damaskos C, Garmpis N, Gkoufa A, Chlapoutakis S, Sklapani P, et al: Asymptomatic SARS-CoV-2 infection in an unvaccinated 97-year-old woman: A case report. Biomed Rep. 15(107)2021.PubMed/NCBI View Article : Google Scholar

10 

Georgakopoulou VE, Basoulis D, Voutsinas PM, Makrodimitri S, Samara S, Triantafyllou M, Eliadi I, Karamanakos G, Papageorgiou CV, Anastasopoulou A, et al: Factors predicting poor outcomes of patients treated with tocilizumab for COVID-19-associated pneumonia: A retrospective study. Exp Ther Med. 24(724)2022.PubMed/NCBI View Article : Google Scholar

11 

Kokkoris S, Gkoufa A, Maneta E, Doumas G, Mizi E, Georgakopoulou VE, Sigala I, Dima E, Papachatzakis I, Ntaidou TK, et al: Older adults with severe coronavirus disease 2019 admitted to intensive care unit: prevalence, characteristics and risk factors for mortality. Minerva Anestesiol. 88:803–814. 2022.PubMed/NCBI View Article : Google Scholar

12 

Gkoufa A, Maneta E, Ntoumas GN, Georgakopoulou VE, Mantelou A, Kokkoris S and Routsi C: Elderly adults with COVID-19 admitted to intensive care unit: A narrative review. World J Crit Care Med. 10:278–289. 2021.PubMed/NCBI View Article : Google Scholar

13 

Gottlieb RL, Vaca CE, Paredes R, Mera J, Webb BJ, Perez G, Oguchi G, Ryan P, Nielsen BU, Brown M, et al: Early Remdesivir to prevent progression to severe covid-19 in outpatients. N Engl J Med. 386:305–315. 2022.PubMed/NCBI View Article : Google Scholar

14 

Kintrilis N and Galinos I: Outpatient intravenous remdesivir to prevent progression to severe COVID-19: An observational study from a Greek hospital. Recent Adv Antiinfect Drug Discov: Mar 31, 2023 (Epub ahead of print).

15 

Aye TT, Myat K, Tun HP, Thiha P, Han TM, Win YY and Han AMM: Early initiation of remdesivir and its effect on oxygen desaturation: A clinical review study among high-risk COVID-19 patients in Myanmar. J Family Med Prim Care. 11:4644–4649. 2022.PubMed/NCBI View Article : Google Scholar

16 

Gáspár Z, Szabó BG, Ábrahám A, Várnai Z, Kiss-Dala N, Szlávik J, Sinkó J, Vályi-Nagy I and Lakatos B: Outcomes of high-risk adult outpatients treated with early remdesivir therapy during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron era: Experiences from the national centre of Hungary. Naunyn Schmiedebergs Arch Pharmacol. 396:1857–1862. 2023.PubMed/NCBI View Article : Google Scholar

17 

Mazzitelli M, Trunfio M, Sasset L, Scaglione V, Ferrari A, Mengato D, Gardin S, Bonadiman N, Calandrino L, Agostini E and Cattelan AM: Risk of hospitalization and sequelae in patients with COVID-19 treated with 3-day early remdesivir vs. controls in the vaccine and Omicron era: A real-life cohort study. J Med Virol. 95(e28660)2023.PubMed/NCBI View Article : Google Scholar

18 

Rajme-López S, Martinez-Guerra BA, Zalapa-Soto J, Román-Montes CM, Tamez-Torres KM, González-Lara MF, Hernandez-Gilosul T, Kershenobich-Stalnikowitz D, Sifuentes-Osornio J, Ponce-de-León A and Ruíz-Palacios GM: Early outpatient treatment with remdesivir in patients at high risk for severe COVID-19: A prospective cohort study. Open Forum Infect Dis. 9(ofac502)2022.PubMed/NCBI View Article : Google Scholar

19 

Panagopoulos P, Petrakis V, Trypsianis G and Papazoglou D: Early 3-day course of remdesivir in vaccinated outpatients with SARS-CoV-2 infection. A success story. J Chemother. 34:550–553. 2022.PubMed/NCBI View Article : Google Scholar

20 

Meini S, Bracalente I, Bontempo G, Longo B, De Martino M and Tascini C: Early 3-day course of remdesivir to prevent progression to severe Covid-19 in high-risk patients with hospital-acquired SARS-CoV-2 infection: Preliminary results from two Italian outbreaks. New Microbiol. 45:304–307. 2022.PubMed/NCBI

21 

Takahashi Y, Wakita H, Ishihara T, Okazaki H, Ito A, Iwata M, Sonoda S and Doi Y: Short-course remdesivir for healthcare-associated COVID-19: Case series from a non-acute care hospital. J Infect Chemother. 29:95–97. 2023.PubMed/NCBI View Article : Google Scholar

22 

Adjei S, Hong K, Molinari NM, Bull-Otterson L, Ajani UA, Gundlapalli AV, Harris AM, Hsu J, Kadri SS, Starnes J, et al: Mortality risk among patients hospitalized primarily for COVID-19 during the omicron and delta variant pandemic periods-United States, April 2020-June 2022. MMWR Morb Mortal Wkly Rep. 71:1182–1189. 2022.PubMed/NCBI View Article : Google Scholar

23 

Colaneri M, Amarasinghe N, Rezzonico L, Pieri TC, Segalini E, Sambo M, Roda S, Meloni F, Gregorini M, Rampino T, et al: Early remdesivir to prevent severe COVID-19 in recipients of solid organ transplant: A real-life study from Northern Italy. Int J Infect Dis. 121:157–160. 2022.PubMed/NCBI View Article : Google Scholar

24 

Belli LS, Fondevila C, Cortesi PA, Conti S, Karam V, Adam R, Coilly A, Ericzon BG, Loinaz C, Cuervas-Mons V, et al: Protective role of Tacrolimus, deleterious role of age and comorbidities in liver transplant recipients with covid-19: Results from the ELITA/ELTR multi-center european study. Gastroenterology. 160:1151–1163.e3. 2021.PubMed/NCBI View Article : Google Scholar

25 

Gatti M, Rinaldi M, Bussini L, Bonazzetti C, Pascale R, Pasquini Z, Faní F, Pinho Guedes MN, Azzini AM, Carrara E, et al: Clinical outcome in solid organ transplant recipients affected by COVID-19 compared to general population: a systematic review and meta-analysis. Clin Microbiol Infect. 28:1057–1065. 2022.PubMed/NCBI View Article : Google Scholar

26 

Mikulska M, Testi D, Russo C, Balletto E, Sepulcri C, Bussini L, Dentone C, Magne F, Policarpo S, Campoli C, et al: Outcome of early treatment of SARS-CoV-2 infection in patients with haematological disorders. Br J Haematol. 20:628–639. 2023.PubMed/NCBI View Article : Google Scholar

27 

Passamonti F, Cattaneo C, Arcaini L, Bruna R, Cavo M, Merli F, Angelucci E, Krampera M, Cairoli R, Della Porta MG, et al: Clinical characteristics and risk factors associated with COVID-19 severity in patients with haematological malignancies in Italy: A retrospective, multicentre, cohort study. Lancet Haematol. 7:e737–e745. 2020.PubMed/NCBI View Article : Google Scholar

28 

D'Abramo A, Vita S, Maffongelli G, Beccacece A, Agrati C, Cimini E, Colavita F, Giancola ML, Cavasio A and Nicastri E: Spallanzani COVID-19 Case Investigation Team. Clinical management of patients with B-cell depletion agents to treat or prevent prolonged and severe SARS-COV-2 infection: Defining a treatment pathway. Front Immunol. 13(911339)2022.PubMed/NCBI View Article : Google Scholar

29 

Liu Y, Du X, Chen J, Jin Y, Peng L, Wang HHX, Luo M, Chen L and Zhao Y: Neutrophil-to-lymphocyte ratio as an independent risk factor for mortality in hospitalized patients with COVID-19. J Infect. 81:e6–e12. 2020.PubMed/NCBI View Article : Google Scholar

30 

Mathioudakis N, Zachiotis M, Papadakos S, Triantafyllou M, Karapanou A, Samara S, Karamanakos G, Spandidos DA, Papalexis P, Damaskos C, et al: Onodera's prognostic nutritional index: Comparison of its role in the severity and outcomes of patients with COVID-19 during the periods of alpha, delta and omicron variant predominance. Exp Ther Med. 24(675)2022.PubMed/NCBI View Article : Google Scholar

31 

Karakoyun I, Colak A, Turken M, Altin Z, Arslan FD, Iyilikci V, Yilmaz N and Kose S: Diagnostic utility of C-reactive protein to albumin ratio as an early warning sign in hospitalized severe COVID-19 patients. Int Immunopharmacol. 91(107285)2021.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Georgakopoulou VE, Gkoufa A, Makrodimitri S, Basoulis D, Tsakanikas A, Karamanakos G, Mastrogianni E, Voutsinas PM, Spandidos DA, Papageorgiou CV, Papageorgiou CV, et al: Early 3‑day course of remdesivir for the prevention of the progression to severe COVID‑19 in the elderly: A single‑centre, real‑life cohort study. Exp Ther Med 26: 462, 2023.
APA
Georgakopoulou, V.E., Gkoufa, A., Makrodimitri, S., Basoulis, D., Tsakanikas, A., Karamanakos, G. ... Sipsas, N.V. (2023). Early 3‑day course of remdesivir for the prevention of the progression to severe COVID‑19 in the elderly: A single‑centre, real‑life cohort study. Experimental and Therapeutic Medicine, 26, 462. https://doi.org/10.3892/etm.2023.12161
MLA
Georgakopoulou, V. E., Gkoufa, A., Makrodimitri, S., Basoulis, D., Tsakanikas, A., Karamanakos, G., Mastrogianni, E., Voutsinas, P. M., Spandidos, D. A., Papageorgiou, C. V., Gamaletsou, M. N., Sipsas, N. V."Early 3‑day course of remdesivir for the prevention of the progression to severe COVID‑19 in the elderly: A single‑centre, real‑life cohort study". Experimental and Therapeutic Medicine 26.4 (2023): 462.
Chicago
Georgakopoulou, V. E., Gkoufa, A., Makrodimitri, S., Basoulis, D., Tsakanikas, A., Karamanakos, G., Mastrogianni, E., Voutsinas, P. M., Spandidos, D. A., Papageorgiou, C. V., Gamaletsou, M. N., Sipsas, N. V."Early 3‑day course of remdesivir for the prevention of the progression to severe COVID‑19 in the elderly: A single‑centre, real‑life cohort study". Experimental and Therapeutic Medicine 26, no. 4 (2023): 462. https://doi.org/10.3892/etm.2023.12161
Copy and paste a formatted citation
x
Spandidos Publications style
Georgakopoulou VE, Gkoufa A, Makrodimitri S, Basoulis D, Tsakanikas A, Karamanakos G, Mastrogianni E, Voutsinas PM, Spandidos DA, Papageorgiou CV, Papageorgiou CV, et al: Early 3‑day course of remdesivir for the prevention of the progression to severe COVID‑19 in the elderly: A single‑centre, real‑life cohort study. Exp Ther Med 26: 462, 2023.
APA
Georgakopoulou, V.E., Gkoufa, A., Makrodimitri, S., Basoulis, D., Tsakanikas, A., Karamanakos, G. ... Sipsas, N.V. (2023). Early 3‑day course of remdesivir for the prevention of the progression to severe COVID‑19 in the elderly: A single‑centre, real‑life cohort study. Experimental and Therapeutic Medicine, 26, 462. https://doi.org/10.3892/etm.2023.12161
MLA
Georgakopoulou, V. E., Gkoufa, A., Makrodimitri, S., Basoulis, D., Tsakanikas, A., Karamanakos, G., Mastrogianni, E., Voutsinas, P. M., Spandidos, D. A., Papageorgiou, C. V., Gamaletsou, M. N., Sipsas, N. V."Early 3‑day course of remdesivir for the prevention of the progression to severe COVID‑19 in the elderly: A single‑centre, real‑life cohort study". Experimental and Therapeutic Medicine 26.4 (2023): 462.
Chicago
Georgakopoulou, V. E., Gkoufa, A., Makrodimitri, S., Basoulis, D., Tsakanikas, A., Karamanakos, G., Mastrogianni, E., Voutsinas, P. M., Spandidos, D. A., Papageorgiou, C. V., Gamaletsou, M. N., Sipsas, N. V."Early 3‑day course of remdesivir for the prevention of the progression to severe COVID‑19 in the elderly: A single‑centre, real‑life cohort study". Experimental and Therapeutic Medicine 26, no. 4 (2023): 462. https://doi.org/10.3892/etm.2023.12161
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