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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2023 Volume 26 Issue 4

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Impact Factor: 2.3

Article Open Access

Prognostic biomarker SYK and its correlation with immune infiltrates in glioma

Changxin Wang, Pei Liu, Yu Sun, Ting Liu, Xiaoxiao Xu, Jiamin Guo, Zheng Gong, Haixin Sun, Rui Xu
Article Number: 499
Published online on: 07 September 2023

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Article

Comparison of the clinical efficacy of three cannulated screws with parallel distribution and inverted triangular distribution in the treatment of femoral neck fractures in the elderly

Jiuxiang Liu, Qiang Zuo, Hao Zhou, Xiaowen Huang
Article Number: 498
Published online on: 06 September 2023

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Article Open Access

Morphometric study in thyroid tumors

Iuliana Mohorea, Bogdan Socea, Alexandru Constantin Carâp, Dragoș Șerban, Zenaida Ceaușu, Mihail Ceaușu
Article Number: 497
Published online on: 06 September 2023

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Article Open Access

T‑tube versus internal drainage tube in laparoscopic common bile duct exploration

Hanzhang Dong, Shaobiao Ke, Jiulin Zhan, Mingjian Luo, Xi Liu, Zhiwei Li
Article Number: 496
Published online on: 06 September 2023

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Review Open Access

Clinical treatment for persistent inflammation, immunosuppression and catabolism syndrome in patients with severe acute pancreatitis (Review)

Bo Zhang, Qigui Xiao, Qingyong Ma, Liang Han
Article Number: 495
Published online on: 06 September 2023

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Article Open Access

Effects of Niaoduqing granules on inflammatory response of diabetic kidney disease: A meta‑analysis

Peipei Zhou, Zhenning Hao, Weilong Xu, Jiangyi Yu
Article Number: 494
Published online on: 06 September 2023

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Article

Hedysarum polybotrys polysaccharide attenuates renal inflammatory infiltration and fibrosis in diabetic mice by inhibiting the HMGB1/RAGE/TLR4 pathway

Changqing Xu, Yanxu Chen, Zongmei Liu, Xiaoyan Fu
Article Number: 493
Published online on: 06 September 2023

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Article Open Access

Meta‑analysis of the autophagy‑associated protein LC3 as a prognostic marker in colorectal cancer

Ning Shen, Lijuan Wang, Jingjing Wu, Xuefang Chen, Fengchao Hu, Yi Su
Article Number: 492
Published online on: 06 September 2023

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Case Report

Abnormal brain changes in a patient with vegetarian diet‑induced subacute combined degeneration: A case report

Xiaozhong Li, Huiting Lin, Xuyang Xiang
Article Number: 491
Published online on: 05 September 2023

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Case Report

A giant, rapidly growing intra‑abdominal desmoid tumor of mesenteric origin in an adolescent male: A case report and literature review

Sun Jung Kim, Jung Woo Han, Taehan Yoon, Hyungwook Choi, Yoon Dae Han
Article Number: 490
Published online on: 05 September 2023

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Article Open Access

Association between the presence and genotype of Helicobacter pylori and periodontitis

Rong Li, Yuxiao Luo, Qin Dong, Yuqing Yin, Yiwei Ma, Jiayu Pan, Yaping Pan, Dongmei Zhang
Article Number: 489
Published online on: 04 September 2023

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Article Open Access

Biphasic function of GSK3β in gefitinib‑resistant NSCLC with or without EGFR mutations

Junzhe Li, Xiayu Wu, Xiang-Bo Ji, Changhao He, Shijie Xu, Xianhua Xu
Article Number: 488
Published online on: 04 September 2023

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Article Open Access

lncRNA TINCR promotes the development of cervical cancer via the miRNA‑7/mTOR axis in vitro

Xuan Liu, Cui Xia Wang, Qin Feng, Tao Zhang
Article Number: 487
Published online on: 04 September 2023

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Review Open Access

Role of the tumor microenvironment in the lymphatic metastasis of cervical cancer (Review)

Lufang Wang, Shuyan Yi, Yun Teng, Wenhan Li, Jing Cai
Article Number: 486
Published online on: 01 September 2023

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Article Open Access

Potential inflammatory targets in the integrative health care of patients with sickle cell disease

Shahida A Khan, Saeed H Halawani, Torki Al Zughaibi, Sarah A Khan
Article Number: 485
Published online on: 01 September 2023

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Article Open Access

Cucurbitacin B induces apoptosis in colorectal cells through reactive oxygen species generation and endoplasmic reticulum stress pathways

Jian-Lan Huang, Li Liang, Pei-En Xie, Wei-Liang Sun, Li Wang, Zheng-Wen Cai
Article Number: 484
Published online on: 01 September 2023

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Article

Angiogenic systemic response to the hypoxic microenvironment in prostate tumorigenesis: A pilot study

Cosmin Ene, Ilinca Nicolae, Corina Daniela Ene
Article Number: 483
Published online on: 01 September 2023

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Review Special Issue Open Access

Molecular consideration relevant to the mechanism of the comorbidity between psoriasis and systemic lupus erythematosus (Review)

Yuying Qu, Dongmei Li, Weida Liu, Dongmei Shi
Article Number: 482
Published online on: 29 August 2023

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Review Open Access

Knee osteoarthritis: Current status and research progress in treatment (Review)

Ruizhi Geng, Jiayi Li, Chen Yu, Chaoqun Zhang, Fei Chen, Jie Chen, Haonan Ni, Jiaxu Wang, Kaiqiang Kang, Ziqi Wei, Yongqing Xu, Tao Jin
Article Number: 481
Published online on: 25 August 2023

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Article Open Access

Integrated bioinformatics analysis and experimental validation reveals hub genes of rheumatoid arthritis

Kun Luo, Yumei Zhong, Yanding Guo, Jingwei Nie, Yimei Xu, Haiyan Zhou
Article Number: 480
Published online on: 25 August 2023

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Article Open Access

Spinal‑pelvic sagittal imbalance and paraspinal muscle degeneration in patients with degenerative lumbar spinal stenosis: A monocentric, prospective and observational study

Keyu Zhao, Tianlian Bao, Wupeng Yang, Chunmei Wang, Yongjiang Wang, Tiantian Wang, Bin Xiao, Qingxin Zhang, Feng Gao, Hao Liu, Xiaoyang Tao, Gang Gao, Tinxin Zhang
Article Number: 479
Published online on: 25 August 2023

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Article Open Access

Detection of N‑glycoprotein associated with IgA nephropathy in urine as a potential diagnostic biomarker using glycosylated proteomic analysis

Junjie Liu, Liuguo Wu, Hongjing Gu, Miaomiao Lu, Jiong Zhang, Hongli Zhou
Article Number: 478
Published online on: 23 August 2023

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Case Report Open Access

A rare form of hyperthyroidism leading to the diagnosis of acromegaly: A case report

Iulia-Ștefania Plotuna, Melania Balaș, Ioana Golu, Daniela Amzăr, Mărioara Cornianu, Flore Vărcus, Adrian Vlad, Mihaela Vlad
Article Number: 477
Published online on: 22 August 2023

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Case Report Open Access

Treatment with sivelestat sodium of acute respiratory distress syndrome induced by chemical pneumonitis: A report of three cases

Liang Jing, Xi Peng, Dayong Li, Yusen Qin, Yaqin Song, Wei Zhu
Article Number: 476
Published online on: 22 August 2023

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Article Open Access

Efficacy and safety of flurbiprofen‑axetil combined with nalbuphine pretreatment on remifentanil‑induced postoperative hyperalgesia: A randomized clinical trial

Ying Zhao, Hailing Mu, Jingjing Zhang, Yao Lu
Article Number: 475
Published online on: 22 August 2023

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Article Open Access

Regulation of the stem‑like properties of estrogen receptor‑positive breast cancer cells through NR2E3/NR2C2 signaling

Shanglun Xie, Yaru Hu, Jiacheng Jin, Lingzhi Fu, Cong Zhang, Qing Yang, Yaxin Niu, Zhiyong Sheng
Article Number: 474
Published online on: 22 August 2023

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Article Open Access

Effects and mechanism of Rictor interference in podocyte injury induced by high glucose

Yan Zeng, Changbin Xiong, Yinxiang Chen, Chunyun Yang, Qiuyue Li
Article Number: 473
Published online on: 22 August 2023

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Article Open Access

27‑Gauge vitrectomy vs. 25‑gauge vitrectomy in the management of proliferative diabetic retinopathy with preoperative intravitreal injection of conbercept

Wu Xiang, Dong Fang, Xintong Jiang, Zhaotian Zhang, Chuqi Xiang, Shaofen Huang, Shaochong Zhang, Yantao Wei
Article Number: 472
Published online on: 17 August 2023

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Article Open Access

Anti‑BCMA CAR‑T cell immunotherapy for relapsed or refractory multiple myeloma

Xiaohui Zhang, Chenxi Ouyang, Guofeng Sun, Hongfeng Liu, Junyuan Qi, Xiaohui Suo
Article Number: 471
Published online on: 17 August 2023

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Review Open Access

Long non‑coding RNAs, lipid metabolism and cancer (Review)

Zhen-Dong Zhang, Xin-Rui Hou, Xiao-Lan Cao, Xiao-Ping Wang
Article Number: 470
Published online on: 17 August 2023

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Article Open Access

FOXA2 attenuates lipopolysaccharide‑induced pneumonia by inhibiting the inflammatory response, oxidative stress and apoptosis through blocking of p38/STAT3 signaling

Zhibin Xue, Yinglin Li, Shiji Xiao, Hanqing Zhang, Jianzhang Xu
Article Number: 469
Published online on: 17 August 2023

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Article Open Access

Effect of thymosin β4 on lipopolysaccharide‑stimulated brain microvascular endothelial cell remodeling: A possible role in blood‑brain barrier injury

William Stewart, Christina Hejl, Rakeshwar S. Guleria, Sudhiranjan Gupta
Article Number: 468
Published online on: 17 August 2023

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Article Open Access

Dynamic observation of circRNA and mRNA profiles in a rat model of deep vein thrombosis

Baolan Sun, Xi Cheng, Mu Zhang, Qin Shi, Xinxin Zhao, Xudong Wang, Yuquan Zhang
Article Number: 467
Published online on: 14 August 2023

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Retraction Open Access

[Retracted] Anti‑Semaphorin‑7A single chain antibody demonstrates beneficial effects on pulmonary inflammation during acute lung injury

Xiao Chen, Hailing Wang, Kui Jia, Hao Wang, Tao Ren
Article Number: 466
Published online on: 14 August 2023

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Review Open Access

Protective effects of ginseng and ginsenosides in the development of osteoarthritis (Review)

Jincai Chen, Lin Huang, Xiaofei Liao
Article Number: 465
Published online on: 11 August 2023

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Case Report Open Access

MRI diagnosis of tumor‑like IgG4 masses in bilateral distal ureters: A case report

Jianghui Cao, Anna Gong, Peng An, Ran Chen, Hong Chen, Yong Wang, Ping Gao
Article Number: 464
Published online on: 11 August 2023

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Article Open Access

Effects of DJ‑1 on apoptosis and mitophagy of glomerular podocytes

Jing Xiao, Junjie Tan, Li Yu, Guosheng Liu, Shengyou Yu
Article Number: 463
Published online on: 11 August 2023

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Article Open Access

Early 3‑day course of remdesivir for the prevention of the progression to severe COVID‑19 in the elderly: A single‑centre, real‑life cohort study

Vasiliki Epameinondas Georgakopoulou, Aikaterini Gkoufa, Sotiria Makrodimitri, Dimitrios Basoulis, Aristeidis Tsakanikas, Georgios Karamanakos, Elpida Mastrogianni, Pantazis M. Voutsinas, Demetrios A. Spandidos, Chrysovalantis V. Papageorgiou, Maria N. Gamaletsou, Nikolaos V. Sipsas
Article Number: 462
Published online on: 09 August 2023

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Article

Methylation haplotypes of the insulin gene promoter in children and adolescents with type 1 diabetes: Can a dimensionality reduction approach predict the disease?

Eleni P. Kotanidou, Alexandra Kosvyra, Konstantina Mouzaki, Styliani Giza, Vasiliki Rengina Tsinopoulou, Anastasios Serbis, Ioanna Chouvarda, Assimina Galli‑Tsinopoulou
Article Number: 461
Published online on: 08 August 2023

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Correction Open Access

[Corrigendum] Inhibition of human oral squamous cell carcinoma proliferation and migration by prodrug‑activating suicide gene therapies

Naining Xu, Honglei Tian, Chun Po Fung, Yuntao Lin, Yuling Chen, Guang Zhu, Yuehong Shen, Chuanbin Guo, Hongyu Yang
Article Number: 460
Published online on: 07 August 2023

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Journal Cover
January-2026 Volume 31 Issue 1

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Journal Metrics

Impact Factor: 2.3

Article Open Access

Adiposity indices and bone health amongst Malaysian adults: Evidence from a cross‑sectional study

Wenjian Zhao, Weizheng Zhang, Kok-Yong Chin, Xiaodong Ma, Hashwin Singh Tejpal Singh, Sophia Ogechi Ekeuku, Yuanzhong Wang, Xia Ji, Yang Guo, Sok Kuan Wong, Norliza Muhammad, Teh Rohaila Jamil, Saharuddin Ahmad
Article Number: 28
Published online on: 21 November 2025

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Article Open Access

Ginsenoside Re attenuates homocysteine‑induced endothelial cell ferroptosis through upregulation of GPX4/xCT signaling

Shaolin Li, Chenge Zhao, Shengqin Yu, Kaijing Yang, Shuying Zhang, Sixu Liu
Article Number: 27
Published online on: 21 November 2025

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Case Report Open Access

Intussusception of the initial jejunum secondary to adenoma in the third and fourth portions of the duodenum: A case report

Lingbo Huo, Lixing Ma
Article Number: 26
Published online on: 21 November 2025

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Correction Open Access

[Corrigendum] Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/β‑catenin signaling pathway

Yun Yi, Bing Liao, Ziwen Zheng, Xiaorong Yang, Yunsheng Yang, Yanfang Zhou, Buzhen Tan, Xinfeng Yang
Article Number: 25
Published online on: 19 November 2025

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Article Open Access

Identification of early diagnostic biomarkers in venous thromboembolism: A bioinformatic analysis based on crosstalk between pyroptosis and venous thromboembolism

Shengbin Han, Jingzhe Xu, Chenchen Yu, Hongxi Guan, Shun Ding
Article Number: 24
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 23
Published online on: 17 November 2025

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Article Open Access

Atorvastatin ameliorates chronic subdural hematomas by interrupting the ‘chronic subdural hematoma cycle’ via inhibition of the inflammatory response

Jinqi Yan, Xiaohu Wang, Chen Liang
Article Number: 22
Published online on: 14 November 2025

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Review Open Access

Diagnosis and treatment of invasive fungal disease in children with hematological malignancies after chemotherapy: Challenges and strategies (Review)

Mingxin He, Feng Chen, Xiaomin Xian, Zhi Guo
Article Number: 21
Published online on: 14 November 2025

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Article Open Access

Venetoclax combined with azacitidine for treatment of a blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

Yunching Lai, Xiaolei Chen, Hebing Zhou
Article Number: 20
Published online on: 10 November 2025

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Case Report Open Access

Diagnostic challenge of aneurysmal dermatofibroma mimicking cutaneous metastasis in a patient with lung cancer: A case report

Jong Yun Choi, Heeyang Park, Jangyoun Choi
Article Number: 19
Published online on: 10 November 2025

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Retraction Open Access

[Retracted] miRNA‑30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene

Shan Muhammad, Qingchao Tang, Liu Wei, Qian Zhang, Guiyu Wang, Bilal Umar Muhammad, Kavanjit Kaur, Tatiana Kamchedalova, Zhao Gang, Zheng Jiang, Zheng Liu, Xishan Wang
Article Number: 18
Published online on: 10 November 2025

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Article

Leucine supplementation modulates lipid metabolism and metabolic pathways in mice with type 1 diabetes: A metabolomics study

Jeng-Yuan Yao, De-Tian-Yu Tzeng, Cai-Hong Feng, Gong-Man Xiao, Tian-Ni You, Ru-Yu Zheng
Article Number: 17
Published online on: 06 November 2025

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Case Report Open Access

Chronic maxillary sinusitis masquerading as a maxillary sinus neoplasm: A case report

Ji-Hyeon Oh, Seong-Gon Kim, Su-Young Kim
Article Number: 16
Published online on: 04 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑490‑3p regulates cell proliferation and apoptosis in gastric cancer via direct targeting of AKT1

Hong Yu, Jianying Sun, Shaochang Jiang, Ying Xu
Article Number: 15
Published online on: 04 November 2025

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Article Open Access

A comparison of bridging external fixation vs. combined external fixation for preventing radial height loss in older patients with distal radius fractures

Jingqiao Li, Yipeng Yang, Xu Zhang, Dandan Zhang, Yadong Yu, Rong Chen, Wei Du
Article Number: 14
Published online on: 30 October 2025

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Case Report Open Access

Primary epithelioid angiomatous nodule of the vocal cord: A case report and literature review

Keda Li, Bin Huang, Lubing Cai, Mingqi Huang, Jianping Shi, Mingdi Jin, Ning Qian, Yongkang Guo
Article Number: 13
Published online on: 29 October 2025

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Case Report Open Access

Hepatic perivascular epithelioid cell tumor: A rare mesenchymal tumor with epithelioid features: A case report

Mahmoud Abbas, Benjamin Strücker, Mehmet Haluk Morgül, Andreas Pascher, Wolfgang Hartmann, Eva Wardelmann
Article Number: 12
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Changes in the interstitial cells of Cajal in the gallbladder of guinea pigs fed a lithogenic diet

Lei Huang, Chao Ding, Xinmin Si
Article Number: 11
Published online on: 29 October 2025

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Article

Evaluation of total oxidant status/total antioxidant capacity and DNA damage in neonates with high lactate levels in umbilical cord blood gases

Burcu Cebeci, Aydemir Yalvaç, Derya Büyükkayhan, Dilek Kurnaz, Hakan Çakir, Murat Elevli
Article Number: 10
Published online on: 29 October 2025

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Case Report

Treatment of a mandibular molar with primary failure of eruption: A case report

Ming Guo, Weisheng Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

Effect of the water‑soluble matrix of nanometer pearl powder on the osteogenic differentiation of hFOB1.19 cells

Xinghuanyu Xu, Lin Liu, Wenbai Zhang, Pu Xu
Article Number: 8
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3‑kinase/protein kinase B signaling pathway

Bin Yan, Aikepaer Wubuli, Yidong Liu, Xin Wang
Article Number: 7
Published online on: 27 October 2025

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Article Open Access

Diagnostic significance of the checkpoint kinase 1 gene in high‑grade gastroenteropancreatic neuroendocrine neoplasms

Na Li, Jianduo An, Yanping Hu
Article Number: 6
Published online on: 24 October 2025

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Retraction Open Access

[Retracted] Establishment of ApoE‑knockout mouse model of preeclampsia and relevant mechanisms

Wenjuan Sun, Baoxia Cui, Fanzhen Hong, Yongping Xu
Article Number: 5
Published online on: 23 October 2025

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Investigating the association between uterine fibroids and weight‑bearing joint osteoarthritis based on a bidirectional Mendelian randomization study

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Published online on: 21 October 2025

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Published online on: 21 October 2025

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Published online on: 16 October 2025

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February-2026 Volume 31 Issue 2

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Case Report Open Access

Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

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Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

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Published online on: 05 December 2025

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Published online on: 01 December 2025

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The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

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Article Number: 39
Published online on: 01 December 2025

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[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

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Article Number: 38
Published online on: 01 December 2025

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Published online on: 01 December 2025

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Published online on: 01 December 2025

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Published online on: 28 November 2025

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Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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Published online on: 28 November 2025

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Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
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Published online on: 28 November 2025

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Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

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Article Number: 31
Published online on: 25 November 2025

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Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

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Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

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Published online on: 24 November 2025

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