Spinal gout with intervertebral foramen infiltration: A rare case perfectly mimicking degenerative lumbar disc disease

Hu,Fangke; Xue,Lu; Zhao,Dong; Chen,Chao; Liu,Gang; Yang,Qiang

doi:10.3892/etm.2023.12354

February-2024 Volume 27 Issue 2

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February-2024 Volume 27 Issue 2

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Case Report Open Access

Spinal gout with intervertebral foramen infiltration: A rare case perfectly mimicking degenerative lumbar disc disease

Authors:
- Fangke Hu
- Lu Xue
- Dong Zhao
- Chao Chen
- Gang Liu
- Qiang Yang
View Affiliations / Copyright

Affiliations: Department of Spine Surgery, Tianjin Hospital, Tianjin University, Tianjin 300000, P.R. China

Copyright: © Hu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 66
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Published online on: December 18, 2023

https://doi.org/10.3892/etm.2023.12354
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Abstract

Spinal gout is a relatively rare disease characterized by significant clinical symptoms. In the current study, the first case of spinal gout with tophus in the intervertebral foramen, which perfectly mimicked degenerative lumbar disc disorders, was presented. The patient was a 57‑year‑old man with a medical history of gout who had suffered from progressive neurological deterioration for the last 12 months. Imaging examination revealed bilateral stenosis in the L5/S1 intervertebral foramen, mimicking degenerative lumbar disc disease. Nerve root radiculography and blocking were performed and the neurological symptoms were completely relieved. Open surgery was further performed and unexpectedly, the intra‑operative findings were amorphous chalky white lesions. Histopathology confirmed the diagnosis of spinal gout. After surgery, the patient was prescribed a medication and achieved complete remission of clinical symptoms. No deterioration was found at the 1‑year follow‑up. To the best of our knowledge, this is the first report of spinal gout tophus in intervertebral foramen in the literature. It was concluded that, although intraspinal tophaceous gout is relatively rare, orthopedic surgeons should take it into consideration as a differential diagnosis, particularly if the patient has a medical history of gout. Early diagnosis and timely medical management may possibly be able to avoid neurological compromise and the need for surgery.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Spinal gout with intervertebral foramen infiltration: A rare case perfectly mimicking degenerative lumbar disc disease

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