|
1
|
Gebler A, Zabel O and Seliger B: The
immunomodulatory capacity of mesenchymal stem cells. Trends Mol
Med. 18:128–134. 2012.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Kinnaird T, Stabile E, Burnett MS and
Epstein SE: Bone-marrow-derived cells for enhancing collateral
development: Mechanisms, animal data, and initial clinical
experiences. Circ Res. 95:354–363. 2004.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Kinnaird T, Stabile E, Burnett MS, Lee CW,
Barr S, Fuchs S and Epstein SE: Marrow-derived stromal cells
express genes encoding a broad spectrum of arteriogenic cytokines
and promote in vitro and in vivo arteriogenesis through paracrine
mechanisms. Circ Res. 94:678–685. 2004.PubMed/NCBI View Article : Google Scholar
|
|
4
|
van den Akker F, de Jager SC and Sluijter
JP: Mesenchymal stem cell therapy for cardiac inflammation:
Immunomodulatory properties and the influence of toll-like
receptors. Mediators Inflamm. 2013(181020)2013.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Kyurkchiev D, Bochev I, Ivanova-Todorova
E, Mourdjeva M, Oreshkova T, Belemezova K and Kyurkchve S:
Secretion of immunoregulatory cytokines by mesenchymal stem cells.
World J Stem Cells. 6:552–570. 2014.PubMed/NCBI View Article : Google Scholar
|
|
6
|
van Dijk A, Naaijkens BA, Jurgens WJ,
Nalliah K, Sairras S, van der Pijl RJ, Vo K, Vonk AB, van Rossum
AC, Paulus WJ, et al: Reduction of infarct size by intravenous
injection of uncultured adipose derived stromal cells in a rat
model is dependent on the time point of application. Stem Cell Res.
7:219–229. 2011.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Vela DC, Silva GV, Assad JA, Sousa AL,
Coulter S, Fernandes MR, Perin EC, Willerson JT and Buja LM:
Histopathological study of healing after allogenic mesenchymal stem
cell delivery in myocardial infarction in dogs. J Histochem
Cytochem. 57:167–176. 2009.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Perin EC, Tian M, Marini FC III, Silva GV,
Zhang Y, Baimbridge F, Quan X, Fernandes MR, Gahremanpour A, Young
D, et al: Imaging long-term fate of intramyocardially implanted
mesenchymal stem cells in a porcine myocardial infarction model.
PLoS One. 6(e22949)2011.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Williams AR and Hare JM: Mesenchymal stem
cells: Biology, pathophysiology, translational findings, and
therapeutic implications for cardiac disease. Circ Res.
109:923–940. 2011.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Kern S, Eichler H, Stoeve J, Klüter H and
Bieback K: Comparative analysis of mesenchymal stem cells from bone
marrow, umbilical cord blood, or adipose tissue. Stem Cells.
24:1294–1301. 2006.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Zhou S, Greenberger JS, Epperly MW, Goff
JP, Adler C, Leboff MS and Glowacki J: Age-related intrinsic
changes in human bonemarrow-derived mesenchymal stem cells and
their differentiation to osteoblasts. Aging Cell. 7:335–343.
2008.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Zhang L, Wei Y, Chi Y, Liu D, Yang S, Han
Z and Li Z: Two-step generation of mesenchymal stem/stromal cells
from human pluripotent stem cells with reinforced efficacy upon
osteoarthritis rabbits by HA hydrogel. Cell Biosci.
11(6)2021.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Katsuno Y and Derynck R: Epithelial
plasticity, epithelial-mesenchymal transition, and the TGF-β
family. Dev Cell. 56:726–746. 2021.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Nieto MA, Huang RY, Jackson RA and Thiery
JP: EMT: 2016. Cell. 166:21–45. 2016.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Tian XJ, Zhang H and Xing J: Coupled
reversible and irreversible bistable switches underlying
TGFβ-induced epithelial to mesenchymal transition. Biophys J.
105:1079–1089. 2013.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Bhatia S, Monkman J, Blick T, Pinto C,
Waltham M, Nagaraj SH and Thompson EW: Interrogation of phenotypic
plasticity between epithelial and mesenchymal states in breast
cancer. J Clin Med. 8(893)2019.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Tripathi S, Chakraborty P, Herbert L and
Jolly MK: A mechanism for epithelial-mesenchymal heterogeneity in a
population of cancer cells. PLoS Comput Biol.
16(e1007619)2020.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Fan X, Zhao Z, Wang D and Xiao J: Glycogen
synthase kinase-3 as a key regulator of cognitive function. Acta
Biochim Biophys Sin (Shanghai). 52:219–230. 2020.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Zhou BP, Deng J, Xia W, Xu J, Li YM,
Gunduz M and Hung MC: Dual regulation of snail by
GSK-3beta-mediated phosphorylation in control of
epithelial-mesenchymal transition. Nat Cell Biol. 6:931–940.
2004.PubMed/NCBI View
Article : Google Scholar
|
|
20
|
Vincent T, Neve EP, Johnson JR, Kukalev A,
Rojo F, Albanell J, Pietras K, Virtanen I, Philipson L, Leopold PL,
et al: A SNAIL1-SMAD3/4 transcriptional repressor complex promotes
TGF-beta mediated epithelial-mesenchymal transition. Nat Cell Biol.
11:943–950. 2009.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Nguyen TMX, Vegrichtova M, Tlapakova T,
Krulova M and Krylov V: Epithelial-mesenchymal transition promotes
the differentiation potential of xenopus tropicalis immature
sertoli cells. Stem Cells Int. 2019(8387478)2019.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Zanetti A, Grata M, Etling EB, Panday R,
Villanueva FS and Toma C: Suspension-expansion of bone marrow
results in small mesenchymal stem cells exhibiting increased
transpulmonary passage following intravenous administration. Tissue
Eng Part C Methods. 21:683–692. 2015.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Galipeau J and Sensébé L: Mesenchymal
stromal cells: Clinical challenges and therapeutic opportunities.
Cell Stem Cell. 22:824–833. 2018.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Bazhanov N, Ylostalo JH, Bartosh TJ,
Tiblow A, Mohammadipoor A, Foskett A and Prockop DJ:
Intraperitoneally infused human mesenchymal stem cells form
aggregates with mouse immune cells and attach to peritoneal organs.
Stem Cell Res Ther. 7(27)2016.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Lee RH, Pulin AA, Seo MJ, Kota DJ,
Ylostalo J, Larson BL, Semprun-Prieto L, Delafontaine P and Prockop
DJ: Intravenous hMSCs improve myocardial infarction in mice because
cells embolized in lung are activated to secrete the
anti-inflammatory protein TSG-6. Cell Stem Cell. 5:54–63.
2009.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Yousefi F, Ebtekar M, Soleimani M, Soudi S
and Hashemi SM: Comparison of in vivo immunomodulatory effects of
intravenous and intraperitoneal administration of adipose-tissue
mesenchymal stem cells in experimental autoimmune encephalomyelitis
(EAE). Int Immunopharmacol. 17:608–616. 2013.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Cheng K, Rai P, Plagov A, Lan X, Kumar D,
Salhan D, Rehman S, Malhotra A, Bhargava K, Palestro CJ, et al:
Transplantation of bone marrow-derived MSCs improves
cisplatinum-induced renal injury through paracrine mechanisms. Exp
Mol Pathol. 94:466–473. 2013.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Castelo-Branco MT, Soares ID, Lopes DV,
Buongusto F, Martinusso CA, do Rosario A Jr, Souza SA, Gutfilen B,
Fonseca LM, Elia C, et al: Intraperitoneal but not intravenous
cryopreserved mesenchymal stromal cells home to the inflamed colon
and ameliorate experimental colitis. PLoS One.
7(e33360)2012.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Roddy GW, Oh JY, Lee RH, Bartosh TJ,
Ylostalo J, Coble K, Rosa RH Jr and Prockop DJ: Action at a
distance: Systemically administered adult stem/progenitor cells
(MSCs) reduce inflammatory damage to the cornea without engraftment
and primarily by secretion of TNF-α stimulated gene/protein 6. Stem
Cells. 29:1572–1579. 2011.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Choi H, Lee RH, Bazhanov N, Oh JY and
Prockop DJ: Anti-inflammatory protein TSG-6 secreted by activated
MSCs attenuates zymosan-induced mouse peritonitis by decreasing
TLR2/NF-κB signaling in resident macrophages. Blood. 118:330–338.
2011.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Zhang J, Tian XJ, Zhang H, Teng Y, Li R,
Bai F, Elankumaran S and Xing J: TGF-β-induced
epithelial-to-mesenchymal transition proceeds through stepwise
activation of multiple feedback loops. Sci Signal.
7(ra91)2014.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Chen Q, Yang W, Wang X, Li X, Qi S, Zhang
Y and Gao MQ: TGF-β1 induces EMT in bovine mammary epithelial cells
through the TGFβ1/smad signaling pathway. Cell Physiol Biochem.
43:82–93. 2017.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Jin W, He Y, Li T, Long F, Qin X, Yuan Y,
Gao G, Shakhawat HM, Liu X, Jin G and Zhou Z: Zhou. Rapid and
robust derivation of mesenchymal stem cells from human pluripotent
stem cells via temporal induction of neuralized ectoderm. Cell
Biosci. 12(31)2022.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Kilkenny C, Browne W, Cuthill IC, Emerson
M and Altman DG: NC3Rs Reporting Guidelines Working Group. Animal
research: Reporting in vivo experiments: The ARRIVE guidelines. Br
J Pharmacol. 160:1577–1579. 2010.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Zhang S, Tang Z, Qing B, Tang R, Duan Q,
Ding S and Deng D: Valproic acid promotes the
epithelial-to-mesenchymal transition of breast cancer cells through
stabilization of Snail and transcriptional upregulation of Zeb1.
Eur J Pharmacol. 865(172745)2019.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Yang H, Wang L, Zhao J, Chen Y, Lei Z, Liu
X, Xia W, Guo L and Zhang HT: TGF-β-activated SMAD3/4 complex
transcriptionally upregulates N-cadherin expression in non-small
cell lung cancer. Lung Cancer. 87:249–257. 2015.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Rogel MR, Soni PN, Troken JR, Sitikov A,
Trejo HE and Ridge KM: Vimentin is sufficient and required for
wound repair and remodeling in alveolar epithelial cells. FASEB J.
25:3873–3883. 2011.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Dubon MJ, Yu JY, Choi S and Park KS:
Transforming growth factor β induces bone marrow mesenchymal stem
cell migration via noncanonical signals and N-cadherin. J Cell
Physiol. 233:201–213. 2018.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Setiawan M, Tan XW, Goh TW, Hin-Fai Yam G
and Mehta JS: Inhibiting glycogen synthase kinase-3 and
transforming growth factor-β signaling to promote epithelial
transition of human adipose mesenchymal stem cells. Biochem Biophys
Res Commun. 490:1381–1388. 2017.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Patel P and Woodgett JR: Glycogen synthase
kinase 3: A kinase for all pathways? Curr Top Dev Biol.
123:277–302. 2017.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Li CH, Liu CW, Tsai CH, Peng YJ, Yang YH,
Liao PL, Lee CC, Cheng YW and Kang JJ: Cytoplasmic aryl hydrocarbon
receptor regulates glycogen synthase kinase 3 beta, accelerates
vimentin degradation, and suppresses epithelial–mesenchymal
transition in non-small cell lung cancer cells. Arch Toxicol.
91:2165–2178. 2017.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Song J and Shi W: The concomitant
apoptosis and EMT underlie the fundamental functions of TGF-β. Acta
Biochim Biophys Sin (Shanghai). 50:91–97. 2018.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Guo S, Zhang Y, Zhang Y, Meng F, Li M, Yu
Z, Chen Y and Cui G: Multiple intravenous injections of valproic
acid-induced mesenchymal stem cell from human-induced pluripotent
stem cells improved cardiac function in an acute myocardial
infarction rat model. Biomed Res Int. 2020(2863501)2020.PubMed/NCBI View Article : Google Scholar
|
