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Bartholin's gland cyst with markedly elevated CA19‑9 level: A case report

  • Authors:
    • Weihua Zhao
    • Tongyan Zhang
  • View Affiliations / Copyright

    Affiliations: Laboratory Department, Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, P.R. China, Department of Infectious Diseases, Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, P.R. China
    Copyright: © Zhao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 226
    |
    Published online on: September 18, 2025
       https://doi.org/10.3892/etm.2025.12976
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Abstract

This case report describes a 43‑year‑old woman who presented with a symptomatic left Bartholin's gland cyst accompanied by a markedly elevated serum CA19‑9 levels (>1,000 U/ml). Despite initial concerns for malignancy, comprehensive evaluation, including contrast‑enhanced CT and serial biomarker monitoring, revealed rapid CA19‑9 normalization (83% reduction within 24 h post‑marsupialization), reaching the normal range by day 59 post‑drainage, suggesting an inflammatory etiology. This case underscores two key clinical insights: CA19‑9 elevations exceeding 1,000 U/ml may occur in benign mucinous cysts and short‑interval biomarker reassessment aids in differential diagnosis. These findings expand the current understanding of tumor marker dynamics in benign gynecological pathology.
View Figures

Figure 1

Changes in the serum CA19-9 level.
CA19-9, carbohydrate antigen 19-9.
View References

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Copy and paste a formatted citation
Spandidos Publications style
Zhao W and Zhang T: Bartholin's gland cyst with markedly elevated CA19‑9 level: A case report. Exp Ther Med 30: 226, 2025.
APA
Zhao, W., & Zhang, T. (2025). Bartholin's gland cyst with markedly elevated CA19‑9 level: A case report. Experimental and Therapeutic Medicine, 30, 226. https://doi.org/10.3892/etm.2025.12976
MLA
Zhao, W., Zhang, T."Bartholin's gland cyst with markedly elevated CA19‑9 level: A case report". Experimental and Therapeutic Medicine 30.6 (2025): 226.
Chicago
Zhao, W., Zhang, T."Bartholin's gland cyst with markedly elevated CA19‑9 level: A case report". Experimental and Therapeutic Medicine 30, no. 6 (2025): 226. https://doi.org/10.3892/etm.2025.12976
Copy and paste a formatted citation
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Spandidos Publications style
Zhao W and Zhang T: Bartholin's gland cyst with markedly elevated CA19‑9 level: A case report. Exp Ther Med 30: 226, 2025.
APA
Zhao, W., & Zhang, T. (2025). Bartholin's gland cyst with markedly elevated CA19‑9 level: A case report. Experimental and Therapeutic Medicine, 30, 226. https://doi.org/10.3892/etm.2025.12976
MLA
Zhao, W., Zhang, T."Bartholin's gland cyst with markedly elevated CA19‑9 level: A case report". Experimental and Therapeutic Medicine 30.6 (2025): 226.
Chicago
Zhao, W., Zhang, T."Bartholin's gland cyst with markedly elevated CA19‑9 level: A case report". Experimental and Therapeutic Medicine 30, no. 6 (2025): 226. https://doi.org/10.3892/etm.2025.12976
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