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Case Report Open Access

Ectopic retroperitoneal bronchogenic cyst mimicking an adrenal hematoma: A case report

  • Authors:
    • Mi Meng
    • Yufan Nie
    • Ye He
    • Bo Yu
    • Ni Fu
    • Cheng Yang
    • Di Wu
    • Haoyi Li
    • Lin Lu
    • Xiangyu Xie
    • Qiang Xu
  • View Affiliations / Copyright

    Affiliations: Department of Thoracic Oncology, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563000, P.R. China, Department of Clinical School, Zunyi Medical University, Zunyi, Guizhou 563000, P.R. China, Department of Urology, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563000, P.R. China, Department of Urology, The People's Hospital of Tongliang District, Chongqing 402560, P.R. China
    Copyright: © Meng et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 242
    |
    Published online on: October 10, 2025
       https://doi.org/10.3892/etm.2025.12992
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Abstract

A bronchogenic cyst (BC) is a rare congenital bronchopulmonary malformation, typically found in the thoracic cavity and rarely found in the retroperitoneum. Due to its anatomical location, BCs are often misdiagnosed as adrenal or pancreatic solid tumors on radiological evaluation. The present study reports a case of an ectopic BC (EBC) in a patient who presented with left‑sided lumbar pain and fever. Initial imaging suggested a cyst in the adrenal region, complicated by hemorrhage and infection. However, after posterior laparoscopic surgery, pathological analysis confirmed the diagnosis of an EBC. The present case report highlights the importance of considering BCs as a potential diagnosis in cystic hemorrhagic lesions located in the retroperitoneum, thereby preventing misdiagnosis and providing valuable insight for clinical management.
View Figures

Figure 1

CT scan showing a thin-walled,
sheet-like, soft tissue-like-density shadow in the left
retroperitoneal region, with no enhancement on contrast scan (red
lines indicate the diameter of the cyst). (A) Non-contrast CT scan.
(B) Contrast-enhanced transverse CT scan. CT, computed
tomography.

Figure 2

Gross appearance of the surgically
resected ectopic bronchogenic cyst. (A) Inner wall of the cyst,
which contains a brownish fluid. (B) The cyst is connected to the
adrenal gland (as indicated by the red lines).

Figure 3

Pathological images of the
bronchogenic cyst (H&E staining). (A) Cyst wall lined with
pseudostratified ciliated columnar epithelium, with fibrous
connective tissue visible in the stroma. (B) Presence of hyaline
cartilage was observed in the inner epithelial lining (H&E
stain; magnification, x100).

Figure 4

Postoperative immunohistochemical
analysis of the bronchogenic cyst revealed positive expression of
(A) CK7, (B) TTF-1 and (C) p63 in the epithelial cells, while (D)
Napsin A, (E) Pax8 and (F) ER were negative. CK7 and Napsin A
showed cytoplasmic localization, whereas TTF-1, P63, Pax8 and ER
were localized in the nucleus (magnification, x400). CK,
cytokeratin; TTF-1, thyroid transcription factor 1; ER, estrogen
receptor; Pax8, paired box 8.
View References

1 

Pederiva F, Rothenberg SS, Hall N, Ijsselstijn H, Wong KKY, von der Thüsen J, Ciet P, Achiron R, Pio d'Adamo A and Schnater JM: Congenital lung malformations. Nat Rev Dis Primers. 9(60)2023.PubMed/NCBI View Article : Google Scholar

2 

Xie W, Huang Z, Huang Z, Chen Z, Zhang B, Xie L, Zhu L, Lian K and Lin D: Retroperitoneal bronchogenic cyst with fluid-fluid level: A case report and literature review. Exp Ther Med. 25(5)2022.PubMed/NCBI View Article : Google Scholar

3 

Miller RF, Graub M and Pashuck ET: Bronchogenic cysts; anomalies resulting from maldevelopment of the primitive foregut and midgut. Am J Roentgenol Radium Ther Nucl Med. 70:771–785. 1953.PubMed/NCBI

4 

Weissferdt A: Non-neoplastic thoracic cysts: A clinicopathologic study of 136 cases. Am J Surg Pathol. 47:1349–1363. 2023.PubMed/NCBI View Article : Google Scholar

5 

Matsumoto H, Hasegawa S, Maezawa Y, Okauchi S, Ohara G, Iguchi K, Kawai H, Takayashiki N and Satoh H: An atypical presentation of bronchogenic cyst. Klin Onkol. 39:463–466. 2024.PubMed/NCBI View Article : Google Scholar

6 

Sumiyoshi K, Shimizu S, Enjoji M, Iwashita A and Kawakami K: Bronchogenic cyst in the abdomen. Virchows Arch A Pathol Anat Histopathol. 408:93–98. 1985.PubMed/NCBI View Article : Google Scholar

7 

Hernandorena González M, Joudanin Seijo JR, Sanchís García JM and Pina Pallín M: Unusual location of a bronchogenic cyst simulating a pancreatic tumor. Radiologia. 52:465–468. 2010.PubMed/NCBI View Article : Google Scholar : (In Spanish).

8 

Obando J, Merkle E and Bean SM: A retroperitoneal bronchogenic cyst. Clin Gastroenterol Hepatol. 7:A24–e21. 2009.PubMed/NCBI View Article : Google Scholar

9 

Govaerts K, Van Eyken P, Verswijvel G and Van der Speeten K: A bronchogenic cyst, presenting as a retroperitoneal cystic mass. Rare Tumors. 4(e13)2012.PubMed/NCBI View Article : Google Scholar

10 

Jiang B, Xie T, Hu J, Xu Y and Zhang H: Retroperitoneal bronchogenic cyst: A case report and literature review. Front Oncol. 14(1406270)2024.PubMed/NCBI View Article : Google Scholar

11 

Fu GS, Wang SF, Wang YN, Han FG, Xu Y, Wei YY, Zhang F, Duan QC and Zhang J: Clinical analysis of 21 cases of children with ectopic bronchogenic cyst. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 59:941–946. 2024.PubMed/NCBI View Article : Google Scholar : (In Chinese).

12 

Gu X, Zhu L, Li Y, Yin B and Wang Z: Imaging findings and misdiagnosis of bronchogenic cysts: A study of 83 cases. J Belg Soc Radiol. 107(81)2023.PubMed/NCBI View Article : Google Scholar

13 

Topal U: Bronchogenic cysts: Radiologic findings. Tani Girisim Radyol. 9:333–338. 2003.PubMed/NCBI(In Turkish).

14 

Park JW, Jeong WG, Lee JE, Lee HJ, Ki SY, Lee BC, Kim HO, Kim SK, Heo SH, Lim HS, et al: Pictorial review of mediastinal masses with an emphasis on magnetic resonance imaging. Korean J Radiol. 22:139–154. 2021.PubMed/NCBI View Article : Google Scholar

15 

Gostomczyk K, Borowczak J, Zdrenka M and Szylberg Ł: Atypical presentation of bronchogenic cyst in the retroperitoneal space. Cureus. 16(e55029)2024.PubMed/NCBI View Article : Google Scholar

16 

Moez R, Ouanes Y, Sahnoun W, Mokhtar B, Dali KM, Sellami A, Ben Rhouma S and Nouira Y: Retroperitoneal cystic mass: A rare form of adrenal pheochromocytoma. J Surg Case Rep. 2021(rjab169)2021.PubMed/NCBI View Article : Google Scholar

17 

Mokhtari M and ZeraatianNejadDavani S: Primary adrenal hydatid cyst presenting with arterial hypertension. Arch Iran Med. 15:328–330. 2012.PubMed/NCBI

18 

Cao DH, Zheng S, Lv X, Yin R, Liu LR, Yang L, Huang Y and Wei Q: Multilocular bronchogenic cyst of the bilateral adrenal: Report of a rare case and review of literature. Int J Clin Exp Pathol. 7:3418–3422. 2014.PubMed/NCBI

19 

Wang M, He X, Qiu X, Tian C, Li J and Lv M: Retroperitoneal bronchogenic cyst resembling an adrenal tumor with high levels of serum carbohydrate antigen 19-9: A case report. Medicine (Baltimore). 96(e7678)2017.PubMed/NCBI View Article : Google Scholar

20 

Wen Y, Chen W, Chen J and He X: Retroperitoneal bronchogenic cyst resembling an adrenal tumor: Two case reports and literature review. J Int Med Res. 48(300060520925673)2020.PubMed/NCBI View Article : Google Scholar

21 

Elhassan YS, Ronchi CL, Wijewickrama P and Baldeweg SE: Approach to the patient with adrenal hemorrhage. J Clin Endocrinol Metab. 108:995–1006. 2023.PubMed/NCBI View Article : Google Scholar

22 

Arslan S, Sarıkaya Y, Akata D, Özmen MN, Karçaaltıncaba M and Karaosmanoğlu AD: Imaging findings of spontaneous intraabdominal hemorrhage: Neoplastic and non-neoplastic causes. Abdom Radiol (NY). 47:1473–1502. 2022.PubMed/NCBI View Article : Google Scholar

23 

Piskunowicz M, Stefanowicz J, Batko T, Hwang M, Świętoń D, Szarmach A, Back S and Kosiak W: Contrast-enhanced ultrasound of adrenal hemorrhage: A helpful problem solving tool. Med Ultrason. 24:284–289. 2022.PubMed/NCBI View Article : Google Scholar

24 

Singh AK, Neyaz Z, Verma R, Gupta A, Mishra R and Mishra P: Diagnostic yield and safety of percutaneous CT-guided biopsy of retroperitoneal lesions and analysis of imaging features. Acta Radiol. 63:149–158. 2022.PubMed/NCBI View Article : Google Scholar

25 

Al-Jawad M, Yehya B, Katbi E, Abousaadah M and Danial AK: Right-sided retroperitoneal bronchogenic cyst: A case report. Int J Surg Case Rep. 126(110671)2025.PubMed/NCBI View Article : Google Scholar

26 

Yuan K, Shu M, Ma Y, Feng W, Ye J and Yuan Y: Ectopic bronchogenic cyst in the retroperitoneal region: A case report and literature review of adult patients. BMC Surg. 21(347)2021.PubMed/NCBI View Article : Google Scholar

27 

Murakami R, Machida M, Kobayashi Y, Ogura J, Ichikawa T and Kumazaki T: Retroperitoneal bronchogenic cyst: CT and MR imaging. Abdom Imaging. 25:444–447. 2000.PubMed/NCBI View Article : Google Scholar

28 

Qureshi M, Wawryk S and Yap Z: Retroperitoneal bronchogenic cyst: A rare diagnosis of a retroperitoneal mass. Cureus. 17(e76922)2025.PubMed/NCBI View Article : Google Scholar

29 

Runge T, Blank A, Schäfer SC, Candinas D, Gloor B and Angst E: A retroperitoneal bronchogenic cyst mimicking a pancreatic or adrenal mass. Case Rep Gastroenterol. 7:428–432. 2013.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Meng M, Nie Y, He Y, Yu B, Fu N, Yang C, Wu D, Li H, Lu L, Xie X, Xie X, et al: Ectopic retroperitoneal bronchogenic cyst mimicking an adrenal hematoma: A case report. Exp Ther Med 30: 242, 2025.
APA
Meng, M., Nie, Y., He, Y., Yu, B., Fu, N., Yang, C. ... Xu, Q. (2025). Ectopic retroperitoneal bronchogenic cyst mimicking an adrenal hematoma: A case report. Experimental and Therapeutic Medicine, 30, 242. https://doi.org/10.3892/etm.2025.12992
MLA
Meng, M., Nie, Y., He, Y., Yu, B., Fu, N., Yang, C., Wu, D., Li, H., Lu, L., Xie, X., Xu, Q."Ectopic retroperitoneal bronchogenic cyst mimicking an adrenal hematoma: A case report". Experimental and Therapeutic Medicine 30.6 (2025): 242.
Chicago
Meng, M., Nie, Y., He, Y., Yu, B., Fu, N., Yang, C., Wu, D., Li, H., Lu, L., Xie, X., Xu, Q."Ectopic retroperitoneal bronchogenic cyst mimicking an adrenal hematoma: A case report". Experimental and Therapeutic Medicine 30, no. 6 (2025): 242. https://doi.org/10.3892/etm.2025.12992
Copy and paste a formatted citation
x
Spandidos Publications style
Meng M, Nie Y, He Y, Yu B, Fu N, Yang C, Wu D, Li H, Lu L, Xie X, Xie X, et al: Ectopic retroperitoneal bronchogenic cyst mimicking an adrenal hematoma: A case report. Exp Ther Med 30: 242, 2025.
APA
Meng, M., Nie, Y., He, Y., Yu, B., Fu, N., Yang, C. ... Xu, Q. (2025). Ectopic retroperitoneal bronchogenic cyst mimicking an adrenal hematoma: A case report. Experimental and Therapeutic Medicine, 30, 242. https://doi.org/10.3892/etm.2025.12992
MLA
Meng, M., Nie, Y., He, Y., Yu, B., Fu, N., Yang, C., Wu, D., Li, H., Lu, L., Xie, X., Xu, Q."Ectopic retroperitoneal bronchogenic cyst mimicking an adrenal hematoma: A case report". Experimental and Therapeutic Medicine 30.6 (2025): 242.
Chicago
Meng, M., Nie, Y., He, Y., Yu, B., Fu, N., Yang, C., Wu, D., Li, H., Lu, L., Xie, X., Xu, Q."Ectopic retroperitoneal bronchogenic cyst mimicking an adrenal hematoma: A case report". Experimental and Therapeutic Medicine 30, no. 6 (2025): 242. https://doi.org/10.3892/etm.2025.12992
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