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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
March-2026 Volume 31 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Review

Exploring the roots of schizophrenia: Current research and future directions (Review)

  • Authors:
    • Shuang Lv
    • Chunxia Luo
  • View Affiliations / Copyright

    Affiliations: Department of Psychiatry, Guangzhou Kangning Hospital (The Psychiatric Hospital of Guangzhou Civil Administration Bureau), Guangzhou, Guangdong 510430, P.R. China
  • Article Number: 82
    |
    Published online on: January 28, 2026
       https://doi.org/10.3892/etm.2026.13078
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Abstract

Mental health holds critical global significance. However, mental illness remains insufficiently acknowledged worldwide. The prevalence and economic impact of mental disorders continue to rise, contributing notably to increased disability rates. Schizophrenia, with a global lifetime prevalence of ~0.4%, is a leading cause of disability. Currently, revealing the pathological mechanisms of schizophrenia, exploring early objective diagnosis and individualized treatment prediction indicators, and developing more effective treatment technologies are still hotspots in research. Several studies highlight schizophrenia as a severe, multifactorial disorder that directly disrupts brain function and profoundly impacts daily life. This review provides an overview of recent advances in schizophrenia research, summarising current research on the mechanisms of its pathogenesis; both genetic and environmental factors exert a significant influence on schizophrenia. Furthermore, investigations into animal models for schizophrenia research aim to establish more precise models, which will facilitate further exploration of the disease's pathogenesis and therapeutic approaches.

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Copy and paste a formatted citation
Spandidos Publications style
Lv S and Luo C: <p>Exploring the roots of schizophrenia: Current research and future directions (Review)</p>. Exp Ther Med 31: 82, 2026.
APA
Lv, S., & Luo, C. (2026). <p>Exploring the roots of schizophrenia: Current research and future directions (Review)</p>. Experimental and Therapeutic Medicine, 31, 82. https://doi.org/10.3892/etm.2026.13078
MLA
Lv, S., Luo, C."<p>Exploring the roots of schizophrenia: Current research and future directions (Review)</p>". Experimental and Therapeutic Medicine 31.3 (2026): 82.
Chicago
Lv, S., Luo, C."<p>Exploring the roots of schizophrenia: Current research and future directions (Review)</p>". Experimental and Therapeutic Medicine 31, no. 3 (2026): 82. https://doi.org/10.3892/etm.2026.13078
Copy and paste a formatted citation
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Spandidos Publications style
Lv S and Luo C: <p>Exploring the roots of schizophrenia: Current research and future directions (Review)</p>. Exp Ther Med 31: 82, 2026.
APA
Lv, S., & Luo, C. (2026). <p>Exploring the roots of schizophrenia: Current research and future directions (Review)</p>. Experimental and Therapeutic Medicine, 31, 82. https://doi.org/10.3892/etm.2026.13078
MLA
Lv, S., Luo, C."<p>Exploring the roots of schizophrenia: Current research and future directions (Review)</p>". Experimental and Therapeutic Medicine 31.3 (2026): 82.
Chicago
Lv, S., Luo, C."<p>Exploring the roots of schizophrenia: Current research and future directions (Review)</p>". Experimental and Therapeutic Medicine 31, no. 3 (2026): 82. https://doi.org/10.3892/etm.2026.13078
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