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Case Report

Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report

  • Authors:
    • Jingxian Li
    • Fang Wang
    • Yuanshu Du
    • Yonghui Wang
  • View Affiliations / Copyright

    Affiliations: Department of Clinical Medicine, Weifang People's Hospital, Shandong Second Medical University, Weifang, Shandong 261041, P.R. China, Department of Thyroid Surgery, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China, Department of Thyroid Surgery, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China
  • Article Number: 87
    |
    Published online on: February 2, 2026
       https://doi.org/10.3892/etm.2026.13082
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Abstract

More than one‑tenth of the world's population is to some degree affected by goiters. Patients with thyroid nodules usually have no symptoms, but giant retrosternal goiters often causes symptoms such as difficulty breathing due to compression. Surgical operation is currently the main treatment for giant retrosternal goiters. However, retrosternal goiters usually require open chest surgery, which carries considerable risks, increases the rate of recurrence and increases the risk of intraoperative damage to important structures such as the large blood vessels and thoracic ducts. Thyroid artery embolization has been used in the treatment of Graves' disease and as a preoperative treatment prior to thyroidectomy. In March 2025, a 70‑year‑old female presented to Weifang People's Hospital (Shandong, China) with a neck mass and dyspnea. A neck CT scan demonstrated an enlarged left thyroid lobe measuring 7.7x13.0 cm, extending inferiorly into the anterior mediastinum and causing tracheal compression that resulted in rightward displacement and flattening of the trachea. The patient presented with dyspnoea at rest. Given the notable size of the mass, thyroid artery embolization was performed, followed by left thyroidectomy. The surgery was conducted without complications such as hoarseness or hypocalcemia and did not necessitate a thoracotomy. Thyroid artery embolization alleviated the tracheal compression symptoms of the patient, restored oxygen saturation to normal levels and rendered the patient suitable for general anesthesia. The mass was successfully removed through cervical surgery alone, thereby avoiding thoracotomy and minimizing iatrogenic trauma during treatment.

View Figures

Figure 1

(A) Thyroid B-mode ultrasound image of
the patient before thyroid artery embolization showing the mass
with a dimension of 99.3x87.3x50.3 mm. (B) Thyroid color Doppler
ultrasound blood flow signal image before embolization, noting the
marked hypervascularity in the mass. (C) Thyroid B-mode ultrasound
image of the patient after thyroid artery embolization showing the
mass with a dimension of 97.6x40.8 mm. (D) Thyroid color Doppler
ultrasound blood flow signal image after embolization showing that
there is almost no blood flow signal within the mass.

Figure 2

(A) CT images of the mass and trachea
before thyroid artery embolization in the patient. (B) CT images of
the mass and trachea after thyroid artery embolization.

Figure 3

(A) Image of the completely excised
mass. (B) Image when the mass was incised.

Figure 4

Histological analysis after H&E
staining showing that the specimen exhibits multiple nodules within
the mass, exhibiting heterogeneous dimensions, which is
pathognomonic of nodular goiter. Magnification, x100.
View References

1 

Carlé A, Krejbjerg A and Laurberg P: Epidemiology of nodular goitre. Influence of iodine intake. Best Pract Res Clin Endocrinol Metab. 28:465–479. 2014.PubMed/NCBI View Article : Google Scholar

2 

Tartaglia F, Salvatori FM, Pichelli D, Sgueglia M, Blasi S and Custureri F: Preoperative embolization of thyroid arteries in a patient with a large cervicomediastinal hyperfunctioning goiter. Thyroid. 17:787–792. 2007.PubMed/NCBI View Article : Google Scholar

3 

Ramos HE, Braga-Basaria M, Haquin C, Mesa CO, Noronha L, Sandrini R, Carvalho Gde A and Graf H: Preoperative embolization of thyroid arteries in a patient with large multinodular goiter and papillary carcinoma. Thyroid. 14:967–970. 2004.PubMed/NCBI View Article : Google Scholar

4 

Tartaglia F, Salvatori FM, Russo G, Blasi S, Sgueglia M, Tromba L and Berni A: Selective embolization of thyroid arteries for preresection or palliative treatment of large cervicomediastinal goiters. Surg Innov. 18:70–78. 2011.PubMed/NCBI View Article : Google Scholar

5 

Tartaglia F, Sorrenti S, Maturo A and Ulisse S: Selective embolization of the thyroid arteries (SETA): Ten years' experience. Asian J Surg. 42:847–848. 2019.PubMed/NCBI View Article : Google Scholar

6 

Kaushik H, Deshmukh M, Gupte S, Kanchankar N and Dongre A: A case report on primary pulmonary choriocarcinoma. Cureus. 16(e63466)2024.PubMed/NCBI View Article : Google Scholar

7 

Sahoo B, Pitchaimuthu A, Swain PK and Nayak M: Bleeding lymph node mass in a postoperative case of thyroid carcinoma: Transarterial embolization to the rescue. Cureus. 17(e86214)2025.PubMed/NCBI View Article : Google Scholar

8 

Dedecjus M, Tazbir J, Kaurzel Z, Strózyk G, Zygmunt A, Lewiński A and Brzeziński J: Evaluation of selective embolization of thyroid arteries (SETA) as a preresective treatment in selected cases of toxic goitre. Thyroid Res. 2(7)2009.PubMed/NCBI View Article : Google Scholar

9 

Mahzari MM, Alanazi MM, Alabdulkareem YM, Alharbi WA, Alzahrani AS, Alqahtani NA, Ajwah IM and Ardah HI: Efficacy of anti-thyroid medications in patients with Graves' disease. BMC Endocr Disord. 24(180)2024.PubMed/NCBI View Article : Google Scholar

10 

Zhao W, Gao BL, Yang HY, Li H, Song DP, Xiang ST and Shen J: Thyroid arterial embolization to treat Graves' disease. Acta Radiol. 48:186–192. 2007.PubMed/NCBI View Article : Google Scholar

11 

Xiao H, Zhuang W, Wang S, Yu B, Chen G, Zhou M and Wong NC: Arterial embolization: A novel approach to thyroid ablative therapy for Graves' disease. J Clin Endocrinol Metab. 87:3583–3589. 2002.PubMed/NCBI View Article : Google Scholar

12 

Bonnici M, Nevin C and Boo S: Thyroid ima artery embolization for the treatment of Graves' disease and thyroid storm. Radiol Case Rep. 18:2641–2644. 2023.PubMed/NCBI View Article : Google Scholar

13 

Wright CD: Tracheomalacia. Chest Surg Clin N Am. 13:349–357, viii. 2003.PubMed/NCBI View Article : Google Scholar

14 

Tikka T, Nixon IJ, Harrison-Phipps K and Simo R: Predictors of the need for an extracervical approach to intrathoracic goitre. BJS Open. 3:174–179. 2018.PubMed/NCBI View Article : Google Scholar

15 

Ducloux R, Sapoval M and Russ G: Embolization of thyroid arteries in a patient with compressive intrathoracic goiter ineligible to surgery or radioiodine therapy. Ann Endocrinol (Paris). 77:670–674. 2016.PubMed/NCBI View Article : Google Scholar

16 

Yilmaz S and Habibi HA: Safety of thyroidal artery embolization. J Vasc Interv Radiol. 33(200)2022.PubMed/NCBI View Article : Google Scholar

17 

Yilmaz S, Habibi HA, Yildiz A and Altunbas H: Thyroid embolization for nonsurgical treatment of nodular goiter: A single-center experience in 56 consecutive patients. J Vasc Interv Radiol. 32:1449–1456. 2021.PubMed/NCBI View Article : Google Scholar

18 

Meyer C, Anderson D, Dong Z, Riddick JB, Elrod M and Ayala M: Prediction of thyroid hormone replacement following thyroid lobectomy: A long-term retrospective study. OTO Open. 5(2473974x21992001)2021.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Li J, Wang F, Du Y and Wang Y: <p>Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report</p>. Exp Ther Med 31: 87, 2026.
APA
Li, J., Wang, F., Du, Y., & Wang, Y. (2026). <p>Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report</p>. Experimental and Therapeutic Medicine, 31, 87. https://doi.org/10.3892/etm.2026.13082
MLA
Li, J., Wang, F., Du, Y., Wang, Y."<p>Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report</p>". Experimental and Therapeutic Medicine 31.4 (2026): 87.
Chicago
Li, J., Wang, F., Du, Y., Wang, Y."<p>Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report</p>". Experimental and Therapeutic Medicine 31, no. 4 (2026): 87. https://doi.org/10.3892/etm.2026.13082
Copy and paste a formatted citation
x
Spandidos Publications style
Li J, Wang F, Du Y and Wang Y: <p>Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report</p>. Exp Ther Med 31: 87, 2026.
APA
Li, J., Wang, F., Du, Y., & Wang, Y. (2026). <p>Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report</p>. Experimental and Therapeutic Medicine, 31, 87. https://doi.org/10.3892/etm.2026.13082
MLA
Li, J., Wang, F., Du, Y., Wang, Y."<p>Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report</p>". Experimental and Therapeutic Medicine 31.4 (2026): 87.
Chicago
Li, J., Wang, F., Du, Y., Wang, Y."<p>Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report</p>". Experimental and Therapeutic Medicine 31, no. 4 (2026): 87. https://doi.org/10.3892/etm.2026.13082
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