Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
April-2026 Volume 31 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
April-2026 Volume 31 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Sagittal sinus thrombosis in pregnancy: A case report

  • Authors:
    • Zaheera Saadia
    • Misbah Ilyas
    • Jayd Saud Althwiny
    • Fai Alaqel
    • Alanoud Abdullah Alsufayri
    • Lujain Husain Almutairi
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, College of Medicine, Qassim University, Buraydah, Al‑Qassim 52571, Saudi Arabia, Department of Obstetrics and Gynecology, Maternity and Children Hospital, Buraydah, Al‑Qassim 52384, Saudi Arabia, College of Medicine, Qassim University, Buraydah, Al‑Qassim 52571, Saudi Arabia
  • Article Number: 100
    |
    Published online on: February 5, 2026
       https://doi.org/10.3892/etm.2026.13095
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:


Abstract

Cerebral venous sinus thrombosis (CVST) is a rare but serious cause of maternal morbidity. It most frequently occurs during late pregnancy and puerperium, and occurs due to pregnancy‑induced hypercoagulability. The present report documents a 37‑year‑old multiparous woman diagnosed with acute superior sagittal sinus thrombosis involving multiple dural sinuses at 6 weeks gestation. The patient was managed with therapeutic low‑molecular‑weight heparin (enoxaparin 100 mg twice daily) under multidisciplinary supervision throughout pregnancy; at 33 weeks, recurrent headaches and vomiting occurred, but imaging showed no new thrombosis. Delivery by elective cesarean section at 38 weeks resulted in a healthy neonate. Postpartum anticoagulation was transitioned to apixaban for 3 months with complete neurological recovery. Early diagnosis, appropriate anticoagulation and multidisciplinary management are key to favorable maternal and fetal outcomes in CVST during pregnancy. The present case report contributes to the literature that sagittal sinus thrombosis can present in early pregnancy with symptoms, such as headache and vomiting, which overlap with the normal symptoms of pregnancy; therefore, a high index of suspicion should be kept in mind.

View Figures

Figure 1

MRI T1-weighted mid sagittal section.
The arrow shows high intensity in the superior sagittal sinus.
Image was obtained in June 2023.

Figure 2

MRI FLAIR sequence axial section. The
arrow shows loss of normal flow void. Image was obtained in June
2023.

Figure 3

MRI T2-weighted coronal section. The
arrow shows loss of flow void in the superior sagittal sinus. Image
was obtained in June 2023.

Figure 4

MRI T1-weighted sagittal view of the
brain. The arrow shows normal flow voids in the superior sagittal
sinus. Image was obtained in November 2023.

Figure 5

MRI T2-weighted axial section at the
level of the pons. The arrow shows normal flow void of the terminal
superior sagittal sinus and transverse sinuses. Image was obtained
in November 2023.

Figure 6

Follow-up image. MRI T1-weighted
sagittal view of the brain. The arrow shows normal flow voids in
the superior sagittal sinus. Image was obtained in June 2024.
View References

1 

Saposnik G, Barinagarrementeria F, Brown RD Tr, Bushnell CD, Cucchiara B, Cushman M, deVeber G, Ferro JM and Tsai FY: American heart association stroke council and the council on epidemiology and prevention. Diagnosis and management of cerebral venous thrombosis: A statement for healthcare professionals from the American heart association/American stroke association. Stroke. 42:1158–1192. 2011.PubMed/NCBI View Article : Google Scholar

2 

Algahtani H, Bazaid A, Shirah B and Bouges RN: Cerebral venous sinus thrombosis in pregnancy and puerperium: A comprehensive review. Brain Circ. 8:180–187. 2022.PubMed/NCBI View Article : Google Scholar

3 

Cantú C and Barinagarrementeria F: Cerebral venous thrombosis associated with pregnancy and puerperium. Review of 67 cases. Stroke. 24:1880–1884. 1993.PubMed/NCBI View Article : Google Scholar

4 

Coutinho JM: Cerebral venous thrombosis. J Thromb Haemost. 13 (Suppl 1):S238–S244. 2015.PubMed/NCBI View Article : Google Scholar

5 

Silvis SM, de Sousa DA, Ferro JM and Coutinho JM: Cerebral venous thrombosis. Nat Rev Neurol. 13:555–565. 2017.PubMed/NCBI View Article : Google Scholar

6 

James AH: Pregnancy-associated thrombosis. Hematology Am Soc Hematol Educ Program. 2009:277–285. 2009.PubMed/NCBI View Article : Google Scholar

7 

Leach JL, Fortuna RB, Jones BV and Gaskill-Shipley MF: Imaging of cerebral venous thrombosis: Current techniques, spectrum of findings, and diagnostic pitfalls. Radiographics. 26 (Suppl 1):S19–S43. 2006.PubMed/NCBI View Article : Google Scholar

8 

MacGregor EA: Headache in pregnancy. Neurol Clin. 30:835–866. 2012.PubMed/NCBI View Article : Google Scholar

9 

Gestational hypertension and preeclampsia. ACOG practice bulletin number 222. Obstet Gynecol. 135:e237–e260. 2020.PubMed/NCBI View Article : Google Scholar

10 

Swartz RH, Cayley ML, Foley N, Ladhani NNN, Leffert L, Bushnell C, McClure JA and Lindsay MP: The incidence of pregnancy-related stroke: A systematic review and meta-analysis. Int J Stroke. 12:687–697. 2017.PubMed/NCBI View Article : Google Scholar

11 

Tunkel AR, Hasbun R, Bhimraj A, Byers K, Kaplan SL, Scheld WM, van de Beek D, Bleck TP, Garton HJL and Zunt JR: 2017 infectious diseases society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis. 64:e34–e65. 2017.PubMed/NCBI View Article : Google Scholar

12 

Goodwin TM: Hyperemesis gravidarum. Obstet Gynecol Clin North Am. 35:401–417. 2008.PubMed/NCBI View Article : Google Scholar

13 

Ferro JM, Canhão P, Stam J, Bousser MG and Barinagarrementeria F: ISCVT Investigators. Prognosis of cerebral vein and dural sinus thrombosis: Results of the international study on cerebral vein and dural sinus thrombosis. Stroke. 35:664–670. 2004.PubMed/NCBI View Article : Google Scholar

14 

Saposnik G, Bushnell C, Coutinho JM, Field TS, Furie KL, Galadanci N, Kam W, Kirkham FC, McNair ND, Singhal AB, et al: Diagnosis and management of cerebral venous thrombosis: A scientific statement from the American heart association. Stroke. 55:e77–e90. 2024.PubMed/NCBI View Article : Google Scholar

15 

Ferro JM, Bousser MG, Canhão P, Coutinho JM, Crassard I, Dentali F, di Minno M, Maino A, Martinelli I, Masuhr F, et al: European stroke organization guideline for the diagnosis and treatment of cerebral venous thrombosis - endorsed by the European academy of neurology. Eur J Neurol. 24:1203–1213. 2017.PubMed/NCBI View Article : Google Scholar

16 

Bates SM, Greer IA, Middeldorp S, Veenstra DL, Prabulos AM and Vandvik PO: VTE, thrombophilia, antithrombotic therapy, and pregnancy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 141 (2 Suppl):e691S–e736S. 2012.PubMed/NCBI View Article : Google Scholar

17 

Mehraein S, Ortwein H, Busch M, Weih M, Einhäupl K and Masuhr F: Risk of recurrence of cerebral venous and sinus thrombosis during subsequent pregnancy and puerperium. J Neurol Neurosurg Psychiatry. 74:814–816. 2003.PubMed/NCBI View Article : Google Scholar

18 

Aguiar de Sousa D, Canhão P, Crassard I, Coutinho J, Arauz A, Conforto A, Béjot Y, Giroud M and Ferro JM: ISCVT-2-PREGNANCY Investigators. Safety of pregnancy after cerebral venous thrombosis: Results of the ISCVT (international study on cerebral vein and dural sinus thrombosis)-2 PREGNANCY study. Stroke. 48:3130–3133. 2017.PubMed/NCBI View Article : Google Scholar

19 

Zhou B, Huang SS, Huang C and Liu SY: Cerebral venous sinus thrombosis in pregnancy: A case report. World J Clin Cases. 10:309–315. 2022.PubMed/NCBI View Article : Google Scholar

20 

Khan YM, Al Yaqoubi HN and Fatema N: Complete superior sagittal sinus thrombosis along with subarachnoid hemorrhage during early postpartum period: A rare case report. J Neurol Res. 7:89–93. 2017.

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Saadia Z, Ilyas M, Althwiny JS, Alaqel F, Alsufayri AA and Almutairi LH: <p>Sagittal sinus thrombosis in pregnancy: A case report</p>. Exp Ther Med 31: 100, 2026.
APA
Saadia, Z., Ilyas, M., Althwiny, J.S., Alaqel, F., Alsufayri, A.A., & Almutairi, L.H. (2026). <p>Sagittal sinus thrombosis in pregnancy: A case report</p>. Experimental and Therapeutic Medicine, 31, 100. https://doi.org/10.3892/etm.2026.13095
MLA
Saadia, Z., Ilyas, M., Althwiny, J. S., Alaqel, F., Alsufayri, A. A., Almutairi, L. H."<p>Sagittal sinus thrombosis in pregnancy: A case report</p>". Experimental and Therapeutic Medicine 31.4 (2026): 100.
Chicago
Saadia, Z., Ilyas, M., Althwiny, J. S., Alaqel, F., Alsufayri, A. A., Almutairi, L. H."<p>Sagittal sinus thrombosis in pregnancy: A case report</p>". Experimental and Therapeutic Medicine 31, no. 4 (2026): 100. https://doi.org/10.3892/etm.2026.13095
Copy and paste a formatted citation
x
Spandidos Publications style
Saadia Z, Ilyas M, Althwiny JS, Alaqel F, Alsufayri AA and Almutairi LH: <p>Sagittal sinus thrombosis in pregnancy: A case report</p>. Exp Ther Med 31: 100, 2026.
APA
Saadia, Z., Ilyas, M., Althwiny, J.S., Alaqel, F., Alsufayri, A.A., & Almutairi, L.H. (2026). <p>Sagittal sinus thrombosis in pregnancy: A case report</p>. Experimental and Therapeutic Medicine, 31, 100. https://doi.org/10.3892/etm.2026.13095
MLA
Saadia, Z., Ilyas, M., Althwiny, J. S., Alaqel, F., Alsufayri, A. A., Almutairi, L. H."<p>Sagittal sinus thrombosis in pregnancy: A case report</p>". Experimental and Therapeutic Medicine 31.4 (2026): 100.
Chicago
Saadia, Z., Ilyas, M., Althwiny, J. S., Alaqel, F., Alsufayri, A. A., Almutairi, L. H."<p>Sagittal sinus thrombosis in pregnancy: A case report</p>". Experimental and Therapeutic Medicine 31, no. 4 (2026): 100. https://doi.org/10.3892/etm.2026.13095
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team