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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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April-2026 Volume 31 Issue 4

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International Journal of Molecular Medicine

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report Open Access

Endodontic re‑treatment of the mandibular first molar with six root canals: A case report

  • Authors:
    • Chen Wang
    • Mengyu Liu
  • View Affiliations / Copyright

    Affiliations: Department of Stomatology, Chengdu Third People's Hospital, Qingyang, Chengdu, Sichuan 610031, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 104
    |
    Published online on: February 9, 2026
       https://doi.org/10.3892/etm.2026.13099
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Abstract

Root canal anatomy of the mandibular first molar typically encompasses 3‑4 canals. However, mandibular first molars may contain >4 root canals, emphasizing the need for heightened diligence among clinicians when conducting root canal therapy (RCT) on these teeth. Within the present case report, a 40‑year‑old Chinese female patient presented to The Third People's Hospital of Chengdu (Chengdu, China) in November 2023 with masticatory pain for 2 months in the lower right posterior region, after previous therapy at the People's Hospital of Wenjiang District (Sichuan, China) in July 2008. Examination using angulated radiographs and magnification instruments demonstrated six root canal systems in the mandibular first molar. Root canal re‑treatment was performed and follow‑up at 6 and 24 months was conducted following sealer extrusion. The patient was asymptomatic with decreased periapical radiolucency and area of extruded sealer. The present report highlights the importance of exploration and meticulous interpretation of canal morphology in the absence of advanced imaging techniques, also underscoring the efficient management of intricate root canal anatomy by conventional methods. By documenting this rare six‑canal structure, the present report augments anatomical knowledge of mandibular first molars and reminds clinicians to anticipate unexpected variations during RCT.

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Copy and paste a formatted citation
Spandidos Publications style
Wang C and Liu M: <p>Endodontic re‑treatment of the mandibular first molar with six root canals: A case report</p>. Exp Ther Med 31: 104, 2026.
APA
Wang, C., & Liu, M. (2026). <p>Endodontic re‑treatment of the mandibular first molar with six root canals: A case report</p>. Experimental and Therapeutic Medicine, 31, 104. https://doi.org/10.3892/etm.2026.13099
MLA
Wang, C., Liu, M."<p>Endodontic re‑treatment of the mandibular first molar with six root canals: A case report</p>". Experimental and Therapeutic Medicine 31.4 (2026): 104.
Chicago
Wang, C., Liu, M."<p>Endodontic re‑treatment of the mandibular first molar with six root canals: A case report</p>". Experimental and Therapeutic Medicine 31, no. 4 (2026): 104. https://doi.org/10.3892/etm.2026.13099
Copy and paste a formatted citation
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Spandidos Publications style
Wang C and Liu M: <p>Endodontic re‑treatment of the mandibular first molar with six root canals: A case report</p>. Exp Ther Med 31: 104, 2026.
APA
Wang, C., & Liu, M. (2026). <p>Endodontic re‑treatment of the mandibular first molar with six root canals: A case report</p>. Experimental and Therapeutic Medicine, 31, 104. https://doi.org/10.3892/etm.2026.13099
MLA
Wang, C., Liu, M."<p>Endodontic re‑treatment of the mandibular first molar with six root canals: A case report</p>". Experimental and Therapeutic Medicine 31.4 (2026): 104.
Chicago
Wang, C., Liu, M."<p>Endodontic re‑treatment of the mandibular first molar with six root canals: A case report</p>". Experimental and Therapeutic Medicine 31, no. 4 (2026): 104. https://doi.org/10.3892/etm.2026.13099
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