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International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.
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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.
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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.
International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.
Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.
Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.
Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.
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Parlati ALM, Nardi E, Marzano F, Madaudo C, Di Santo M, Cotticelli C, Agizza S, Abbellito GM, Perrone Filardi F, Del Giudice M, et al: Advancing cardiovascular diagnostics: The expanding role of CMR in heart failure and cardiomyopathies. J Clin Med. 14(865)2025.PubMed/NCBI View Article : Google Scholar | |
|
Bai Y, Zheng JP, Lu F, Zhang XL, Sun CP, Guo WH, Zou YX, Lip GYH and Shi XB: Prevalence, incidence and mortality of hypertrophic cardiomyopathy based on a population cohort of 21.9 million in China. Sci Rep. 12(18799)2022.PubMed/NCBI View Article : Google Scholar | |
|
Wexler RK, Elton T, Pleister A and Feldman D: Cardiomyopathy: An overview. Am Fam Physician. 79:778–784. 2009.PubMed/NCBI | |
|
Li T, Wang N, Yi D, Xiao Y, Li X, Shao B, Wu Z, Bai J, Shi X, Wu C, et al: ROS-mediated ferroptosis and pyroptosis in cardiomyocytes: An update. Life Sci. 370(123565)2025.PubMed/NCBI View Article : Google Scholar | |
|
Wang Y, Zhou T, Zhao J, Zhu H, Tan X, Chen J, Zhang Z, Shen L and Lu S: Calcium handling remodeling in dilated cardiomyopathy: From molecular mechanisms to targeted therapies. Channels (Austin). 19(2519545)2025.PubMed/NCBI View Article : Google Scholar | |
|
Hoskins AC, Jacques A, Bardswell SC, McKenna WJ, Tsang V, dos Remedios CG, Ehler E, Adams K, Jalilzadeh S, Avkiran M, et al: Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy. J Mol Cell Cardiol. 49:737–745. 2010.PubMed/NCBI View Article : Google Scholar | |
|
Tanaka A, Yuasa S, Mearini G, Egashira T, Seki T, Kodaira M, Kusumoto D, Kuroda Y, Okata S, Suzuki T, et al: Endothelin-1 induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell-derived cardiomyocytes. J Am Heart Assoc. 3(e001263)2014.PubMed/NCBI View Article : Google Scholar | |
|
Viola H, Johnstone V, Cserne Szappanos H, Richman T, Tsoutsman T, Filipovska A, Semsarian C and Hool L: The L-type Ca(2+) channel facilitates abnormal metabolic activity in the cTnI-G203S mouse model of hypertrophic cardiomyopathy. J Physiol. 594:4051–4070. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Castillero E, Akashi H, Pendrak K, Yerebakan H, Najjar M, Wang C, Naka Y, Mancini D, Sweeney HL, D Armiento J, et al: Attenuation of the unfolded protein response and endoplasmic reticulum stress after mechanical unloading in dilated cardiomyopathy. Am J Physiol Heart Circ Physiol. 309:H459–H470. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Fan G, Liu T, Chen X, Guo Y, Li X, He Y, Hua P, Lin X, Lin D, Yan X, et al: Astaxanthin prevented acute alcoholic cardiomyopathy by maintenance of mitophagy-mediated mitochondrial homeostasis. J Cell Mol Med. 29(e70714)2025.PubMed/NCBI View Article : Google Scholar | |
|
Zhao T, Jin K, Wang X, Su X, Wang Y, Gao M, Luo W, Yang H and Yang Z: GPAT4 sustains endoplasmic reticulum homeostasis in endocardial cells and safeguards heart development. Nat Commun. 16(3345)2025.PubMed/NCBI View Article : Google Scholar | |
|
Wang J, Pu X, Zhuang H, Guo Z, Wang M, Yang H, Li C and Chang X: Astragaloside IV alleviates septic myocardial injury through DUSP1-Prohibitin 2 mediated mitochondrial quality control and ER-autophagy. J Adv Res. 75:561–580. 2025.PubMed/NCBI View Article : Google Scholar | |
|
Brinkman K, Smeitink JA, Romijn JA and Reiss P: Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy. Lancet. 354:1112–1115. 1999.PubMed/NCBI View Article : Google Scholar | |
|
Liu ZW, Zhu HT, Chen KL, Dong X, Wei J, Qiu C and Xue JH: Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy. Cardiovasc Diabetol. 12(158)2013.PubMed/NCBI View Article : Google Scholar | |
|
Tarazon E, Rosello-Lleti E, Ortega A, Gil-Cayuela C, González-Juanatey JR, Lago F, Martínez-Dolz L, Portolés M and Rivera M: Changes in human Golgi apparatus reflect new left ventricular dimensions and function in dilated cardiomyopathy patients. Eur J Heart Fail. 19:280–282. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Zhang J, Cui J, Zhao F, Yang L, Xu X, Shi Y and Wei B: Cardioprotective effect of MLN4924 on ameliorating autophagic flux impairment in myocardial ischemia-reperfusion injury by Sirt1. Redox Biol. 46(102114)2021.PubMed/NCBI View Article : Google Scholar | |
|
Kaur N, Raja R, Ruiz-Velasco A and Liu W: Cellular protein quality control in diabetic cardiomyopathy: From bench to bedside. Front Cardiovasc Med. 7(585309)2020.PubMed/NCBI View Article : Google Scholar | |
|
Bresilla D, Tawfik I, Hirtl M, Gabrijelčič S, Ostaku J, Mossegger F, Wurzer L, Lederer S, Kalinova K, Malle E, et al: Enhancing late-life survival and mobility via mitohormesis by reducing mitochondrial calcium levels. Aging Cell. 24(e70247)2025.PubMed/NCBI View Article : Google Scholar | |
|
Xu X, Pang Y and Fan X: Mitochondria in oxidative stress, inflammation and aging: From mechanisms to therapeutic advances. Signal Transduct Target Ther. 10(190)2025.PubMed/NCBI View Article : Google Scholar | |
|
Chen X, Yuan T, Zheng D, Li F, Xu H, Ye M, Liu S and Li J: Cardiomyocyte mitochondrial mono-ADP-ribosylation dictates cardiac tolerance to sepsis by configuring bioenergetic reserve in male mice. Nat Commun. 16(8119)2025.PubMed/NCBI View Article : Google Scholar | |
|
Huang J, Meng P, Liang Y, Li X, Zhou S, Li J, Wang X, Miao J, Shen W and Zhou L: Tubular CD44 plays a key role in aggravating AKI through NF-ĸB p65-mediated mitochondrial dysfunction. Cell Death Dis. 16(119)2025.PubMed/NCBI View Article : Google Scholar | |
|
Elbatarny M, Lu YT, Hu M, Coles J, Mital S, Ross-White A, Honjo O, Barron DJ and Gramolini AO: Systems biology approaches investigating mitochondrial dysfunction in cyanotic heart disease: A systematic review. EBioMedicine. 118(105839)2025.PubMed/NCBI View Article : Google Scholar | |
|
Tran DH and Wang ZV: Glucose metabolism in cardiac hypertrophy and heart failure. J Am Heart Assoc. 8(e012673)2019.PubMed/NCBI View Article : Google Scholar | |
|
Xu Y, Zhang X, Tang X, Zhang C, Cahoon JG, Wang Y, Li H, Lv X, Wang Y, Wang Z, et al: Dexmedetomidine post-treatment exacerbates metabolic disturbances in septic cardiomyopathy via α2A-adrenoceptor. Biomed Pharmacother. 170(115993)2024.PubMed/NCBI View Article : Google Scholar | |
|
Gallo G, Rubattu S and Volpe M: Mitochondrial dysfunction in heart failure: From pathophysiological mechanisms to therapeutic opportunities. Int J Mol Sci. 25(2667)2024.PubMed/NCBI View Article : Google Scholar | |
|
Wu M, Tan J, Cao Z, Cai Y, Huang Z, Chen Z, He W, Liu X, Jiang Y, Gao Q, et al: Sirt5 improves cardiomyocytes fatty acid metabolism and ameliorates cardiac lipotoxicity in diabetic cardiomyopathy via CPT2 de-succinylation. Redox Biol. 73(103184)2024.PubMed/NCBI View Article : Google Scholar | |
|
Guo Y, Zhang Z, Wen Z, Kang X, Wang D, Zhang L, Cheng M, Yuan G and Ren H: Mitochondrial SIRT2-mediated CPT2 deacetylation prevents diabetic cardiomyopathy by impeding cardiac fatty acid oxidation. Int J Biol Sci. 21:725–744. 2025.PubMed/NCBI View Article : Google Scholar | |
|
Hu Y, Zheng Y, Liu C, You Y, Wu Y, Wang P, Wu Y, Ba H, Lu J, Yuan Y, et al: Mitochondrial MOF regulates energy metabolism in heart failure via ATP5B hyperacetylation. Cell Rep. 43(114839)2024.PubMed/NCBI View Article : Google Scholar | |
|
Bonora M, Wieckowski MR, Sinclair DA, Kroemer G, Pinton P and Galluzzi L: Targeting mitochondria for cardiovascular disorders: Therapeutic potential and obstacles. Nat Rev Cardiol. 16:33–55. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Wang P, Xu S, Xu J, Xin Y, Lu Y, Zhang H, Zhou B, Xu H, Sheu SS, Tian R and Wang W: Elevated MCU expression by CaMKIIdeltaB limits pathological cardiac remodeling. Circulation. 145:1067–1083. 2022.PubMed/NCBI View Article : Google Scholar | |
|
Garcia-Pena LM, Abel ED and Pereira RO: Mitochondrial dynamics, diabetes, and cardiovascular disease. Diabetes. 73:151–161. 2024.PubMed/NCBI View Article : Google Scholar | |
|
Alves-Figueiredo H, Silva-Platas C, Estrada M, Oropeza-Almazán Y, Ramos-González M, Bernal-Ramírez J, Vázquez-Garza E, Tellez A, Salazar-Ramírez F, Méndez-Fernández A, et al: Mitochondrial Ca(2+) uniporter-dependent energetic dysfunction drives hypertrophy in heart failure. JACC Basic Transl Sci. 9:496–518. 2024.PubMed/NCBI View Article : Google Scholar | |
|
Niu W, Liu X, Deng B, Hong T, Wang C, Yan Y, Liu J, Jiang Y and Li J: Piezo1 deletion mitigates diabetic cardiomyopathy by maintaining mitochondrial dynamics via ERK/Drp1 pathway. Cardiovasc Diabetol. 24(127)2025.PubMed/NCBI View Article : Google Scholar | |
|
Tokuyama T, Uosaki H, Sugiura A, Nishitai G, Takeda K, Nagashima S, Shiiba I, Ito N, Amo T, Mohri S, et al: Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation. iScience. 25(104582)2022.PubMed/NCBI View Article : Google Scholar | |
|
Thakkar C, Alikunju S, Venkatasubramanian A, D'Mello D, Abbas H, Yang Z, Andreas I, Sayed N, Abdellatif M and Sayed D: Constitutive expression of cardiomyocyte Klf9 precipitates metabolic dysfunction and spontaneous cardiomyopathy. Cell Signal. 136(112146)2025.PubMed/NCBI View Article : Google Scholar | |
|
Lazarou M, Sliter DA, Kane LA, Sarraf SA, Wang C, Burman JL, Sideris DP, Fogel AI and Youle RJ: The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy. Nature. 524:309–314. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Kubli DA, Zhang X, Lee Y, Hanna RA, Quinsay MN, Nguyen CK, Jimenez R, Petrosyan S, Murphy AN and Gustafsson AB: Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction. J Biol Chem. 288:915–926. 2013.PubMed/NCBI View Article : Google Scholar | |
|
Vujic A, Koo ANM, Prag HA and Krieg T: Mitochondrial redox and TCA cycle metabolite signaling in the heart. Free Radic Biol Med. 166:287–296. 2021.PubMed/NCBI View Article : Google Scholar | |
|
Wang X, Li J, Zhang Y, Huang M, Yang P, Huang T and Cheng Q: HIF1A/BNIP3 pathway affects ferroptosis in sepsis-induced cardiomyopathy through binding to BCL-2. Redox Rep. 30(2544412)2025.PubMed/NCBI View Article : Google Scholar | |
|
Chen W, Zhao Z, Geng Z, Zhang H and Fu X: Advances in mitochondria-nucleus crosstalk in septic cardiomyopathy. Cell Biol Toxicol. 41(136)2025.PubMed/NCBI View Article : Google Scholar | |
|
Liu H, Liu X, Zhou J and Li T: Mitochondrial DNA Is a vital driving force in ischemia-reperfusion injury in cardiovascular diseases. Oxid Med Cell Longev. 2022(6235747)2022.PubMed/NCBI View Article : Google Scholar | |
|
Lopes LR, Macken WL, Preez SD, Kotwal H, Savvatis K, Sekhri N, Mohiddin SA, Kabiljo R and Pitceathly RDS: An analysis of mitochondrial variation in cardiomyopathy patients from the 100,000 genomes cohort: m.4300A>G as a cause of genetically elusive hypertrophic cardiomyopathy. Hum Genomics. 18(136)2024.PubMed/NCBI View Article : Google Scholar | |
|
Constante AD, Abreu SM and Trigo C: Mitochondrial cardiomyopathy: A puzzle for the final diagnosis. Cardiol Young. 34:1393–1396. 2024.PubMed/NCBI View Article : Google Scholar | |
|
Tragni V, Primiano G, Tummolo A, Cafferati Beltrame L, La Piana G, Sgobba MN, Cavalluzzi MM, Paterno G, Gorgoglione R, Volpicella M, et al: Personalized medicine in mitochondrial health and disease: Molecular basis of therapeutic approaches based on nutritional supplements and their analogs. Molecules. 27(3494)2022.PubMed/NCBI View Article : Google Scholar | |
|
Luppi E, De Luise M, Bini C, Pelletti G, Tioli G, Kurelac I, Iommarini L, Pelotti S and Gasparre G: The landscape of rare mitochondrial DNA variants in sudden cardiac death: A potential role for ATP synthase. Heliyon. 11(e41592)2024.PubMed/NCBI View Article : Google Scholar | |
|
Lee JS, Ko YG, Shin KJ, Kim SK, Park JH, Hwang KC and Pak HN: Mitochondrial DNA 4977bp deletion mutation in peripheral blood reflects atrial remodeling in patients with non-valvular atrial fibrillation. Yonsei Med J. 56:53–61. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Zhang Y, Sun X, Jin Y, Chen K, Zhang L, Gao X, Li M, Yuan Z, Jia J, Sun A and Ge J: Mitochondrial transplantation augments the reparative capacity of macrophages following myocardial injury. Adv Sci (Weinh). 12(e06337)2025.PubMed/NCBI View Article : Google Scholar | |
|
Lin H, Xiong W, Fu L, Yi J and Yang J: Damage-associated molecular patterns (DAMPs) in diseases: Implications for therapy. Mol Biomed. 6(60)2025.PubMed/NCBI View Article : Google Scholar | |
|
Yu H, Ren K, Jin Y, Zhang L, Liu H, Huang Z, Zhang Z, Chen X, Yang Y and Wei Z: Mitochondrial DAMPs: Key mediators in neuroinflammation and neurodegenerative disease pathogenesis. Neuropharmacology. 264(110217)2025.PubMed/NCBI View Article : Google Scholar | |
|
Oka T, Hikoso S, Yamaguchi O, Taneike M, Takeda T, Tamai T, Oyabu J, Murakawa T, Nakayama H, Nishida K, et al: Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure. Nature. 485:251–255. 2012.PubMed/NCBI View Article : Google Scholar | |
|
He B, Yu H, Liu S, Wan H, Fu S, Liu S, Yang J, Zhang Z, Huang H, Li Q, et al: Mitochondrial cristae architecture protects against mtDNA release and inflammation. Cell Rep. 41(111774)2022.PubMed/NCBI View Article : Google Scholar | |
|
Mweene BC, Hatwiko H, Povia JP and Masenga SK: The role of mitochondrial dysfunction and dynamics in hypertensive heart disease: Mechanisms and recent advances. Biology (Basel). 14(1212)2025.PubMed/NCBI View Article : Google Scholar | |
|
Yan J, Cao J, Pan W and Chen L: Insights into golgi apparatus and centrosome: Implications for ciliogenesis. Mol Biol Rep. 52(716)2025.PubMed/NCBI View Article : Google Scholar | |
|
Ferrer MF, Rozes-Salvador V, Tomatis C, Thomas P, Aquila S, Aguiar MCAM, Carrera Silva EA, Alvarez C and Gómez RM: Yellow fever virus induces golgi stress and CREB3L1 nuclear translocation in human A549 cells. J Med Virol. 97(e70490)2025.PubMed/NCBI View Article : Google Scholar | |
|
Cui C, Sun C, Yuan P, Tian S, Xie H, Xu F and Li H: The golgi apparatus as a strategic target in cancer: Mechanisms, diagnosis and therapeutic opportunities. J Drug Target. 33:1773–1787. 2025.PubMed/NCBI View Article : Google Scholar | |
|
Wijaya CS and Xu S: Reevaluating Golgi fragmentation and its implications in wound repair. Cell Regen. 13(4)2024.PubMed/NCBI View Article : Google Scholar | |
|
Gonzalez-Torrent I, Gimenez-Escamilla I, Perez-Carrillo L, Delgado-Arija M, Portolés M, Tarazón E and Roselló-Lletí E: Alteration in Golgi apparatus fragmentation related genes in human dilated cardiomyopathy. Sci Rep. 15(7704)2025.PubMed/NCBI View Article : Google Scholar | |
|
Jungk L, Franke H, Salameh A and Dhein S: Golgi fragmentation in human patients with chronic atrial fibrillation: A new aspect of remodeling. Thorac Cardiovasc Surg. 67:98–106. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Zemet R, Hope KD, Edmondson AC, Shah R, Patino M, Yesso AM, Berger JH, Sarafoglou K, Larson A, Lam C, et al: Cardiomyopathy, an uncommon phenotype of congenital disorders of glycosylation: Recommendations for baseline screening and follow-up evaluation. Mol Genet Metab. 142(108513)2024.PubMed/NCBI View Article : Google Scholar | |
|
Raja R, Fonseka O, Ganenthiran H, Andrea-Ruiz-Velasco and Liu W: The multifaceted roles of ER and Golgi in metabolic cardiomyopathy. Front Cardiovasc Med. 9(999044)2022.PubMed/NCBI View Article : Google Scholar | |
|
Chatham JC and Patel RP: Protein glycosylation in cardiovascular health and disease. Nat Rev Cardiol. 21:525–544. 2024.PubMed/NCBI View Article : Google Scholar | |
|
Yu P, Hu L, Xie J, Chen S, Huang L, Xu Z, Liu X, Zhou Q, Yuan P, Yan X, et al: O-GlcNAcylation of cardiac Nav1.5 contributes to the development of arrhythmias in diabetic hearts. Int J Cardiol. 260:74–81. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Fang R, Jiang Q, Jia X and Jiang Z: ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING. Immunity. 56:500–515 e6. 2023.PubMed/NCBI View Article : Google Scholar | |
|
Brandizzi F and Barlowe C: Organization of the ER-Golgi interface for membrane traffic control. Nat Rev Mol Cell Biol. 14:382–392. 2013.PubMed/NCBI View Article : Google Scholar | |
|
Sikder K, Phillips E, Zhong Z, Wang N, Saunders J, Mothy D, Kossenkov A, Schneider T, Nichtova Z, Csordas G, et al: Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy. Sci Adv. 10(eadh0798)2024.PubMed/NCBI View Article : Google Scholar | |
|
Lu LQ, Tang MZ, Qi ZH, Huang SF, He YQ, Li DK, Li LF and Chen LX: Regulation of the Golgi apparatus via GOLPH3-mediated new selective autophagy. Life Sci. 253(117700)2020.PubMed/NCBI View Article : Google Scholar | |
|
Chen Y, Wu Y, Tian X, Shao G, Lin Q and Sun A: Golgiphagy: A novel selective autophagy to the fore. Cell Biosci. 14(130)2024.PubMed/NCBI View Article : Google Scholar | |
|
Kitta S, Kaminishi T, Higashi M, Shima T, Nishino K, Nakamura N, Kosako H, Yoshimori T and Kuma A: YIPF3 and YIPF4 regulate autophagic turnover of the Golgi apparatus. EMBO J. 43:2954–2978. 2024.PubMed/NCBI View Article : Google Scholar | |
|
Huang Y and Klionsky DJ: Identification of the YIPF3-YIPF4 heterodimer as a novel Golgiphagy receptor. Autophagy. 20:1211–1212. 2024.PubMed/NCBI View Article : Google Scholar | |
|
Kang J, Li CM, Kim N, Baek J and Jung YK: Non-autophagic Golgi-LC3 lipidation facilitates TFE3 stress response against Golgi dysfunction. EMBO J. 43:5085–5113. 2024.PubMed/NCBI View Article : Google Scholar | |
|
Li A, Liu Y, Labapuchi Chen Z, Li S, Zhong R, Cheng D, Chen L and He L: Development of a Golgi-targeted fluorescent chemosensor for detecting ferrous ions overload under Golgi stress. Spectrochim Acta A Mol Biomol Spectrosc. 294(122560)2023.PubMed/NCBI View Article : Google Scholar | |
|
Reiling JH, Olive AJ, Sanyal S, Carette JE, Brummelkamp TR, Ploegh HL, Starnbach MN and Sabatini DM: A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens. Nat Cell Biol. 15:1473–1485. 2013.PubMed/NCBI View Article : Google Scholar | |
|
Prola A, Nichtova Z, Pires Da Silva J, Piquereau J, Monceaux K, Guilbert A, Gressette M, Ventura-Clapier R, Garnier A, Zahradnik I, et al: Endoplasmic reticulum stress induces cardiac dysfunction through architectural modifications and alteration of mitochondrial function in cardiomyocytes. Cardiovasc Res. 115:328–342. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Borbein W, Dahmlos L, Saleem U, Reinsch M, Braren I, Schulze T, Klampe B, Cuello F, Stenzig J, Eschenhagen T and Hansen A: Altered endoplasmic reticulum calcium loading in human PLN-R14del cardiomyopathy. Front Cell Dev Biol. 13(1627985)2025.PubMed/NCBI View Article : Google Scholar | |
|
Tandra V, Zhang L, Lee CM, Wu Y, Yue G, Li H, Su H and Li J: ufmylation suppresses unfolded protein response to prevent peripartum cardiomyopathy. JACC Basic Transl Sci. 10(101293)2025.PubMed/NCBI View Article : Google Scholar | |
|
Chen J, Yang X, Li W, Lin Y, Lin R, Cai X, Yan B, Xie B and Li J: Endoplasmic reticulum stress-related gene expression causes the progression of dilated cardiomyopathy by inducing apoptosis. Front Genet. 15(1366087)2024.PubMed/NCBI View Article : Google Scholar | |
|
Bhattarai KR, Chaudhary M, Kim HR and Chae HJ: Endoplasmic reticulum (ER) stress response failure in diseases. Trends Cell Biol. 30:672–675. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Bond Newton SE, Shi X, Beratan NR, Perhacs J, Arya JK, Bond MK, Gidalevitz T, Akay-Espinoza C, Brady DC and Jordan-Sciutto KL: ER stress tolerance is regulated by copper-dependent PERK kinase activity. Cell Rep. 44(116318)2025.PubMed/NCBI View Article : Google Scholar | |
|
Wang S, Binder P, Fang Q, Wang Z, Xiao W, Liu W and Wang X: Endoplasmic reticulum stress in the heart: insights into mechanisms and drug targets. Br J Pharmacol. 175:1293–1304. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Qiu Y, Chen Z, He P and Wang Z: Endoplasmic reticulum stress in cardiomyopathies: From the unfolded protein response to therapeutic opportunities. Front Cardiovasc Med. 12(1577186)2025.PubMed/NCBI View Article : Google Scholar | |
|
Bertolotti A, Zhang Y, Hendershot LM, Harding HP and Ron D: Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat Cell Biol. 2:326–332. 2000.PubMed/NCBI View Article : Google Scholar | |
|
Han J, Back SH, Hur J, Lin YH, Gildersleeve R, Shan J, Yuan CL, Krokowski D, Wang S, Hatzoglou M, et al: ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. Nat Cell Biol. 15:481–490. 2013.PubMed/NCBI View Article : Google Scholar | |
|
Fu F and Doroudgar S: IRE1/XBP1 and endoplasmic reticulum signaling - from basic to translational research for cardiovascular disease. Curr Opin Physiol. 28(100552)2022.PubMed/NCBI View Article : Google Scholar | |
|
Nakatsukasa K, Huyer G, Michaelis S and Brodsky JL: Dissecting the ER-associated degradation of a misfolded polytopic membrane protein. Cell. 132:101–112. 2008.PubMed/NCBI View Article : Google Scholar | |
|
Zhu Z, Pu J, Li Y, Chen J, Ding H, Zhou A and Zhang X: RBM25 regulates hypoxic cardiomyocyte apoptosis through CHOP-associated endoplasmic reticulum stress. Cell Stress Chaperones. 28:861–876. 2023.PubMed/NCBI View Article : Google Scholar | |
|
Schiattarella GG, Altamirano F, Kim SY, Tong D, Ferdous A, Piristine H, Dasgupta S, Wang X, French KM, Villalobos E, et al: Xbp1s-FoxO1 axis governs lipid accumulation and contractile performance in heart failure with preserved ejection fraction. Nat Commun. 12(1684)2021.PubMed/NCBI View Article : Google Scholar | |
|
Li C, Qian T, He R, Wan C, Liu Y and Yu H: Endoplasmic reticulum-plasma membrane contact sites: Regulators, mechanisms, and physiological functions. Front Cell Dev Biol. 9(627700)2021.PubMed/NCBI View Article : Google Scholar | |
|
Chen C, Dai G, Fan M, Wang X, Niu K and Gao W: Mitochondria-associated endoplasmic reticulum membranes and myocardial ischemia: from molecular mechanisms to therapeutic strategies. J Transl Med. 23(277)2025.PubMed/NCBI View Article : Google Scholar | |
|
Feno S, Rizzuto R, Raffaello A and Vecellio Reane D: The molecular complexity of the mitochondrial calcium uniporter. Cell Calcium. 93(102322)2021.PubMed/NCBI View Article : Google Scholar | |
|
Bai X, Zhang Z, Li X, Yang Y and Ding S: FUNDC1: An emerging mitochondrial and MAMs protein for mitochondrial quality control in heart diseases. Int J Mol Sci. 24(9151)2023.PubMed/NCBI View Article : Google Scholar | |
|
Szabadkai G, Bianchi K, Varnai P, De Stefani D, Wieckowski MR, Cavagna D, Nagy AI, Balla T and Rizzuto R: Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels. J Cell Biol. 175:901–911. 2006.PubMed/NCBI View Article : Google Scholar | |
|
Ong SB, Samangouei P, Kalkhoran SB and Hausenloy DJ: The mitochondrial permeability transition pore and its role in myocardial ischemia reperfusion injury. J Mol Cell Cardiol. 78:23–34. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Zhihao L, Jingyu N, Lan L, Michael S, Rui G, Xiyun B, Xiaozhi L and Guanwei F: SERCA2a: A key protein in the Ca(2+) cycle of the heart failure. Heart Fail Rev. 25:523–535. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Zsebo K, Yaroshinsky A, Rudy JJ, Wagner K, Greenberg B, Jessup M and Hajjar RJ: Long-term effects of AAV1/SERCA2a gene transfer in patients with severe heart failure: analysis of recurrent cardiovascular events and mortality. Circ Res. 114:101–108. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Lyon AR, Babalis D, Morley-Smith AC, Hedger M, Suarez Barrientos A, Foldes G, Couch LS, Chowdhury RA, Tzortzis KN, Peters NS, et al: Investigation of the safety and feasibility of AAV1/SERCA2a gene transfer in patients with chronic heart failure supported with a left ventricular assist device - the SERCA-LVAD TRIAL. Gene Ther. 27:579–590. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Nakagama S, Maejima Y, Fan Q, Shiheido-Watanabe Y, Tamura N, Ihara K and Sasano T: Endoplasmic reticulum selective autophagy alleviates anthracycline-induced cardiotoxicity. JACC CardioOncol. 5:656–670. 2023.PubMed/NCBI View Article : Google Scholar | |
|
Kuijpers M, Kochlamazashvili G, Stumpf A, Puchkov D, Swaminathan A, Lucht MT, Krause E, Maritzen T, Schmitz D and Haucke V: Neuronal autophagy regulates presynaptic neurotransmission by controlling the axonal endoplasmic reticulum. Neuron. 109:299–313 e9. 2021.PubMed/NCBI View Article : Google Scholar | |
|
Stolz A, Ernst A and Dikic I: Cargo recognition and trafficking in selective autophagy. Nat Cell Biol. 16:495–501. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Wang H, Liu L, Gong H and Li H: Upregulation of FAM134B inhibits endoplasmic reticulum stress-related degradation protein expression and promotes hepatocellular carcinogenesis. J Cell Mol Med. 28(e17964)2024.PubMed/NCBI View Article : Google Scholar | |
|
Qu Y, Gao R, Wei X, Sun X, Yang K, Shi H, Gao Y, Hu S, Wang Y, Yang J, et al: Gasdermin D mediates endoplasmic reticulum stress via FAM134B to regulate cardiomyocyte autophagy and apoptosis in doxorubicin-induced cardiotoxicity. Cell Death Dis. 13(901)2022.PubMed/NCBI View Article : Google Scholar | |
|
Wiersma M, Meijering RAM, Qi XY, Zhang D, Liu T, Hoogstra-Berends F, Sibon OCM, Henning RH, Nattel S and Brundel BJJM: Endoplasmic reticulum stress is associated with autophagy and cardiomyocyte remodeling in experimental and human atrial fibrillation. J Am Heart Assoc. 6(e006458)2017.PubMed/NCBI View Article : Google Scholar | |
|
Pires Da Silva J, Monceaux K, Guilbert A, Gressette M, Piquereau J, Novotova M, Ventura-Clapier R, Garnier A and Lemaire C: SIRT1 protects the heart from ER stress-induced injury by promoting eEF2K/eEF2-dependent autophagy. Cells. 9(426)2020.PubMed/NCBI View Article : Google Scholar | |
|
Karwi QG, Ho KL, Pherwani S, Ketema EB, Sun Q and Lopaschuk GD: Concurrent diabetes and heart failure: Interplay and novel therapeutic approaches. Cardiovasc Res. 118:686–715. 2022.PubMed/NCBI View Article : Google Scholar | |
|
Wang T, Wei Q, Liang L, Tang X, Yao J, Lu Y, Qu Y, Chen Z, Xing G and Cao X: OSBPL2 is required for the binding of COPB1 to ATGL and the regulation of lipid droplet lipolysis. iScience. 23(101252)2020.PubMed/NCBI View Article : Google Scholar | |
|
Kaur N, Ruiz-Velasco A, Raja R, Howell G, Miller JM, Abouleisa RRE, Ou Q, Mace K, Hille SS, Frey N, et al: Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy. iScience. 25(103973)2022.PubMed/NCBI View Article : Google Scholar | |
|
Fonseka O, Raja R, Ross C, Gare SR, Zhang J, Hille SS, King K, Ruiz-Velasco A, Kaur N, Chen X, et al: XBP1s-EDEM2 prevents the onset and development of HFpEF by ameliorating cardiac lipotoxicity. Circulation. 151:1583–1605. 2025.PubMed/NCBI View Article : Google Scholar | |
|
Yu L, Chen Y and Tooze SA: Autophagy pathway: Cellular and molecular mechanisms. Autophagy. 14:207–215. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Zhou R, Zhang Z, Li X, Duan Q, Miao Y, Zhang T, Wang M, Li J, Zhang W, Wang L, et al: Autophagy in high-fat diet and streptozotocin-induced metabolic cardiomyopathy: Mechanisms and therapeutic implications. Int J Mol Sci. 26(1668)2025.PubMed/NCBI View Article : Google Scholar | |
|
Gu S, Tan J, Li Q, Liu S, Ma J, Zheng Y, Liu J, Bi W, Sha P, Li X, et al: Downregulation of LAPTM4B contributes to the impairment of the autophagic flux via unopposed activation of mTORC1 signaling during myocardial ischemia/reperfusion injury. Circ Res. 127:e148–e165. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Qiao L, Hu J, Qiu X, Wang C, Peng J, Zhang C, Zhang M, Lu H and Chen W: LAMP2A, LAMP2B and LAMP2C: Similar structures, divergent roles. Autophagy. 19:2837–2852. 2023.PubMed/NCBI View Article : Google Scholar | |
|
Ma X, Liu H, Foyil SR, Godar RJ, Weinheimer CJ, Hill JA and Diwan A: Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia/reperfusion injury. Circulation. 125:3170–3181. 2012.PubMed/NCBI View Article : Google Scholar | |
|
Zhao YT, Cao XQ and Mu XL: Hypertrophic cardiomyopathy secondary to deficiency in lysosome-associated membrane protein-2: A case report. World J Cardiol. 15:609–614. 2023.PubMed/NCBI View Article : Google Scholar | |
|
Pan B, Zhang H, Cui T and Wang X: TFEB activation protects against cardiac proteotoxicity via increasing autophagic flux. J Mol Cell Cardiol. 113:51–62. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Ma X, Godar RJ, Liu H and Diwan A: Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death. Autophagy. 8:297–309. 2012.PubMed/NCBI View Article : Google Scholar | |
|
Patel S, Radhakrishnan D, Kumari D, Bhansali P and Setty SRG: Restoration of β-GC trafficking improves the lysosome function in Gaucher disease. Traffic. 24:489–503. 2023.PubMed/NCBI View Article : Google Scholar | |
|
Beyer JN, Serebrenik YV, Toy K, Najar MA, Feierman E, Raniszewski NR, Korb E, Shalem O and Burslem GM: Intracellular protein editing enables incorporation of noncanonical residues in endogenous proteins. Science. 388(eadr5499)2025.PubMed/NCBI View Article : Google Scholar | |
|
Azevedo O, Cordeiro F, Gago MF, Miltenberger-Miltenyi G, Ferreira C, Sousa N and Cunha D: Fabry disease and the heart: A comprehensive review. Int J Mol Sci. 22(4434)2021.PubMed/NCBI View Article : Google Scholar | |
|
Huang W, Zhou R, Jiang C, Wang J, Zhou Y, Xu X, Wang T, Li A and Zhang Y: Mitochondrial dysfunction is associated with hypertrophic cardiomyopathy in Pompe disease-specific induced pluripotent stem cell-derived cardiomyocytes. Cell Prolif. 57(e13573)2024.PubMed/NCBI View Article : Google Scholar | |
|
Chen YY, Liu CX, Liu HX and Wen SY: The emerging roles of vacuolar-type ATPase-dependent lysosomal acidification in cardiovascular disease. Biomolecules. 15(525)2025.PubMed/NCBI View Article : Google Scholar | |
|
Kim YC, Park HW, Sciarretta S, Mo JS, Jewell JL, Russell RC, Wu X, Sadoshima J and Guan KL: Rag GTPases are cardioprotective by regulating lysosomal function. Nat Commun. 5(4241)2014.PubMed/NCBI View Article : Google Scholar | |
|
Kinouchi K, Ichihara A, Sano M, Sun-Wada GH, Wada Y, Kurauchi-Mito A, Bokuda K, Narita T, Oshima Y, Sakoda M, et al: The (pro)renin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes. Circ Res. 107:30–34. 2010.PubMed/NCBI View Article : Google Scholar | |
|
Qi J, Li Q, Xin T, Lu Q, Lin J, Zhang Y, Luo H, Zhang F, Xing Y, Wang W, et al: MCOLN1/TRPML1 in the lysosome: A promising target for autophagy modulation in diverse diseases. Autophagy. 20:1712–1722. 2024.PubMed/NCBI View Article : Google Scholar | |
|
Medina DL and Ballabio A: Lysosomal calcium regulates autophagy. Autophagy. 11:970–971. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Scotto Rosato A, Montefusco S, Soldati C, Di Paola S, Capuozzo A, Monfregola J, Polishchuk E, Amabile A, Grimm C, Lombardo A, et al: TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway. Nat Commun. 10(5630)2019.PubMed/NCBI View Article : Google Scholar | |
|
Xing Y, Sui Z, Liu Y, Wang MM, Wei X, Lu Q, Wang X, Liu N, Lu C, Chen R, et al: Blunting TRPML1 channels protects myocardial ischemia/reperfusion injury by restoring impaired cardiomyocyte autophagy. Basic Res Cardiol. 117(20)2022.PubMed/NCBI View Article : Google Scholar | |
|
McGirr T, Onar O and Jafarnejad SM: Dysregulated ribosome quality control in human diseases. FEBS J. 292:936–959. 2025.PubMed/NCBI View Article : Google Scholar | |
|
Gobet C and Naef F: Ribosome profiling and dynamic regulation of translation in mammals. Curr Opin Genet Dev. 43:120–127. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Ganapathi M, Argyriou L, Martinez-Azorin F, Morlot S, Yigit G, Lee TM, Auber B, von Gise A, Petrey DS, Thiele H, et al: Bi-allelic missense disease-causing variants in RPL3L associate neonatal dilated cardiomyopathy with muscle-specific ribosome biogenesis. Hum Genet. 139:1443–1454. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Liu WY, Wang HQ and Shao ZH: Research progress on pathogenesis of congenital pure red cell aplasia-review. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 29:1654–1657. 2021.PubMed/NCBI View Article : Google Scholar : (In Chinese). | |
|
Desai N, Yang H, Chandrasekaran V, Kazi R, Minczuk M and Ramakrishnan V: Elongational stalling activates mitoribosome-associated quality control. Science. 370:1105–1110. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Balch WE, Morimoto RI, Dillin A and Kelly JW: Adapting proteostasis for disease intervention. Science. 319:916–919. 2008.PubMed/NCBI View Article : Google Scholar | |
|
Juszkiewicz S, Chandrasekaran V, Lin Z, Kraatz S, Ramakrishnan V and Hegde RS: ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol Cell. 72:469–481 e7. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Douglas T, Zhang J, Wu Z, Abdallah K, McReynolds M, Gilbert WV, Iwai K, Peng J, Young LH and Crews CM: An atypical E3 ligase safeguards the ribosome during nutrient stress bioRxiv [Preprint] 2024.10.10.617692, 2024. | |
|
Wang Y, Tu J, Wu W, Xu Y, Li Y, Pan X, Liu B, Lu T, Han Q, Zhang H, et al: The orchestration of cell-cycle reentry and ribosome biogenesis network is critical for cardiac repair. Theranostics. 14:3927–3944. 2024.PubMed/NCBI View Article : Google Scholar | |
|
Qu JH, Tarasov KV, Chakir K, Tarasova YS, Riordon DR and Lakatta EG: Proteomic landscape and deduced functions of the cardiac 14-3-3 protein interactome. Cells. 11(3496)2022.PubMed/NCBI View Article : Google Scholar | |
|
Sciarretta S, Forte M, Frati G and Sadoshima J: The complex network of mTOR signalling in the heart. Cardiovasc Res. 118:424–439. 2022.PubMed/NCBI View Article : Google Scholar | |
|
Yano T, Ferlito M, Aponte A, Kuno A, Miura T, Murphy E and Steenbergen C: Pivotal role of mTORC2 and involvement of ribosomal protein S6 in cardioprotective signaling. Circ Res. 114:1268–1280. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Ye T, Yan Z, Chen C, Wang D, Wang A, Li T, Yang B, Ding X and Shen C: Lactoferrin attenuates cardiac fibrosis and cardiac remodeling after myocardial infarction via inhibiting mTORC1/S6K signaling pathway. Theranostics. 13:3419–3433. 2023.PubMed/NCBI View Article : Google Scholar | |
|
Zhang G, Wang X, Li C, Li Q, An YA, Luo X, Deng Y, Gillette TG, Scherer PE and Wang ZV: Integrated stress response couples mitochondrial protein translation with oxidative stress control. Circulation. 144:1500–1515. 2021.PubMed/NCBI View Article : Google Scholar | |
|
Wang Z, Wu J, Lv Z, Liang P, Li Q, Li Y and Guo Y: LMNA-related cardiomyopathy: From molecular pathology to cardiac gene therapy. J Adv Res. 77:443–464. 2025.PubMed/NCBI View Article : Google Scholar | |
|
Chen SN, Lombardi R, Karmouch J, Tsai JY, Czernuszewicz G, Taylor MRG, Mestroni L, Coarfa C, Gurha P and Marian AJ: DNA damage response/TP53 pathway is activated and contributes to the pathogenesis of dilated cardiomyopathy associated with LMNA (Lamin A/C) mutations. Circ Res. 124:856–873. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Veltrop RJA, Kukk MM, Topouzidou K, Didden L, Muchir A, van Steenbeek FG, Schurgers LJ and Harakalova M: From gene to mechanics: A comprehensive insight into the mechanobiology of LMNA mutations in cardiomyopathy. Cell Commun Signal. 22(197)2024.PubMed/NCBI View Article : Google Scholar | |
|
Cenni V, Evangelisti C, Santi S, Sabatelli P, Neri S, Cavallo M, Lattanzi G and Mattioli E: Desmin and plectin recruitment to the nucleus and nuclei orientation are lost in emery-dreifuss muscular dystrophy myoblasts subjected to mechanical stimulation. Cells. 13(162)2024.PubMed/NCBI View Article : Google Scholar | |
|
Bulmer L, Ljungman C, Hallin J, Dahlberg P, Polte CL, Hedberg-Oldfors C, Oldfors A and Gummesson A: EMD missense variant causes X-linked isolated dilated cardiomyopathy with myocardial emerin deficiency. Eur J Hum Genet. 33:775–783. 2025.PubMed/NCBI View Article : Google Scholar | |
|
Nielsen MS, van Opbergen CJM, van Veen TAB and Delmar M: The intercalated disc: A unique organelle for electromechanical synchrony in cardiomyocytes. Physiol Rev. 103:2271–2319. 2023.PubMed/NCBI View Article : Google Scholar | |
|
Yeruva S and Waschke J: Structure and regulation of desmosomes in intercalated discs: Lessons from epithelia. J Anat. 242:81–90. 2023.PubMed/NCBI View Article : Google Scholar | |
|
Zhao G, Qiu Y, Zhang HM and Yang D: Intercalated discs: Cellular adhesion and signaling in heart health and diseases. Heart Fail Rev. 24:115–132. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Sheikh F, Ross RS and Chen J: Cell-cell connection to cardiac disease. Trends Cardiovasc Med. 19:182–190. 2009.PubMed/NCBI View Article : Google Scholar | |
|
Wang L, Liu S, Zhang H, Hu S and Wei Y: Arrhythmogenic cardiomyopathy: Identification of desmosomal gene variations and desmosomal protein expression in variation carriers. Exp Ther Med. 15:2255–2262. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Pruna M and Ehler E: The intercalated disc: A mechanosensing signalling node in cardiomyopathy. Biophys Rev. 12:931–946. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Rickelt S and Pieperhoff S: Mutations with pathogenic potential in proteins located in or at the composite junctions of the intercalated disk connecting mammalian cardiomyocytes: A reference thesaurus for arrhythmogenic cardiomyopathies and for Naxos and Carvajal diseases. Cell Tissue Res. 348:325–333. 2012.PubMed/NCBI View Article : Google Scholar | |
|
Mishra Y, Kumar A and Kaundal RK: Mitochondrial Dysfunction is a Crucial Immune Checkpoint for Neuroinflammation and Neurodegeneration: mtDAMPs in Focus. Mol Neurobiol. 62:6715–6747. 2025.PubMed/NCBI View Article : Google Scholar | |
|
Zhang G, Wei H, Zhao A, Yan X, Zhang X, Gan J, Guo M, Wang J, Zhang F, Jiang Y, et al: Mitochondrial DNA leakage: underlying mechanisms and therapeutic implications in neurological disorders. J Neuroinflammation. 22(34)2025.PubMed/NCBI View Article : Google Scholar | |
|
Guan X, Li H, Zhang L and Zhi H: Mechanisms of mitochondrial damage-associated molecular patterns associated with inflammatory response in cardiovascular diseases. Inflamm Res. 74(18)2025.PubMed/NCBI View Article : Google Scholar | |
|
Du Q, Ning N, Zhao X, Liu F, Zhang S, Xia Y, Li F, Yuan S, Xie X, Zhu M, et al: Acylglycerol kinase inhibits macrophage anti-tumor activity via limiting mtDNA release and cGAS-STING-type I IFN response. Theranostics. 15:1304–1319. 2025.PubMed/NCBI View Article : Google Scholar | |
|
Rabinowitz J, Vila IK, Luchsinger C, Bertelli C, Schüssler M, Taffoni C, Cui B, Dai AZ, Rashid MM, Cisneros WJ, et al: The ability of SAMHD1-deficient monocytes to trigger the type I IFN response depends on cGAS and mitochondrial DNA. J Biol Chem. 301(110430)2025.PubMed/NCBI View Article : Google Scholar | |
|
Calixto A, Moen KE and Moreno SNJ: The contribution of the Golgi and the endoplasmic reticulum to calcium and pH homeostasis in Toxoplasma gondii. J Biol Chem. 301(108372)2025.PubMed/NCBI View Article : Google Scholar | |
|
Sun W, Zhang J, Li S, Fu W, Liu Y, Liu M, Dong J, Zhao X and Li X: TAB2 deficiency induces dilated cardiomyopathy by promoting mitochondrial calcium overload in human iPSC-derived cardiomyocytes. Mol Med. 31(42)2025.PubMed/NCBI View Article : Google Scholar | |
|
He P, Chang H, Qiu Y and Wang Z: Mitochondria associated membranes in dilated cardiomyopathy: Connecting pathogenesis and cellular dysfunction. Front Cardiovasc Med. 12(1571998)2025.PubMed/NCBI View Article : Google Scholar | |
|
Zhao WB and Sheng R: The correlation between mitochondria-associated endoplasmic reticulum membranes (MAMs) and Ca(2+) transport in the pathogenesis of diseases. Acta Pharmacol Sin. 46:271–291. 2025.PubMed/NCBI View Article : Google Scholar | |
|
Benyair R, Eisenberg-Lerner A and Merbl Y: Maintaining Golgi homeostasis: A balancing act of two proteolytic pathways. Cells. 11(780)2022.PubMed/NCBI View Article : Google Scholar | |
|
Liu J, Huang Y, Li T, Jiang Z, Zeng L and Hu Z: The role of the Golgi apparatus in disease (Review). Int J Mol Med. 47(38)2021.PubMed/NCBI View Article : Google Scholar | |
|
Raval KK, Tao R, White BE, De Lange WJ, Koonce CH, Yu J, Kishnani PS, Thomson JA, Mosher DF, Ralphe JC and Kamp TJ: Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes. J Biol Chem. 290:3121–3136. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Lu L, Zhou Q, Chen Z and Chen L: The significant role of the Golgi apparatus in cardiovascular diseases. J Cell Physiol. 233:2911–2919. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Sun Z and Brodsky JL: Protein quality control in the secretory pathway. J Cell Biol. 218:3171–3187. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Gallagher CM and Walter P: Ceapins inhibit ATF6alpha signaling by selectively preventing transport of ATF6α to the Golgi apparatus during ER stress. Elife. 5(e11880)2016.PubMed/NCBI View Article : Google Scholar | |
|
Wang L, Xu Y, Yun S, Yuan Q, Satpute-Krishnan P and Ye Y: SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum. Cell Rep. 42(112028)2023.PubMed/NCBI View Article : Google Scholar | |
|
Izawa T, Park SH, Zhao L, Hartl FU and Neupert W: Cytosolic protein vms1 links ribosome quality control to mitochondrial and cellular homeostasis. Cell. 171:890–903 e18. 2017.PubMed/NCBI View Article : Google Scholar |