|
1
|
Caruso G, Weroha SJ and Cliby W: Ovarian
cancer: A review. JAMA. 334:1278–1291. 2025.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Nie DY, Zhang H, Wang H, Song W, Yuan D,
Zhu D, Mao G, Guo T and Lin M: Artesunate triggers ferroptosis in
ovarian cancer via GP130-mediated IL-6/STAT3/OTUB1/SLC711 axis
disruption. Phytomedicine. 148(157269)2025.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Chen G, Yuan D, Li J, Mao G, Zhang Y, Guo
T and Lin M: Polyphyllin H inhibits malignant progression of
ovarian cancer in patient-derived xenograft mouse models by
regulating CGN/RhoA/Rock2 axis: An experimental research. Int J
Surg. 111:7842–7856. 2025.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Wu F, Liu Y, Luo GQ, Huang DH, Liang WL,
Cao SX, Niu J, Kurihara H, Zhang XH, Li YF, et al: Chaihu Shugan
San formula alleviates psychological stress-induced ovarian cancer
susceptibility by inhibiting ubiquitin degradation of TLR2 in
macrophages. Phytomedicine. 145(156967)2025.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Lajarín-Cuesta R, Arribas RL, Nanclares C,
García-Frutos EM, Gandía L and de Los Ríos C: Design and synthesis
of multipotent 3-aminomethylindoles and 7-azaindoles with enhanced
protein phosphatase 2A-activating profile and neuroprotection. Eur
J Med Chem. 157:294–309. 2018.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Hong Y, Hu HY, Xie X, Sakoda A, Sagehashi
M and Li FM: Gramine-induced growth inhibition, oxidative damage
and antioxidant responses in freshwater cyanobacterium Microcystis
aeruginosa. Aquat Toxicol. 91:262–269. 2009.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Zhang XH, Guo Q, Wang HY, Li YH, Khamis
MY, Ma LY, Wang B and Liu HM: Gramine-based structure optimization
to enhance anti-gastric cancer activity. Bioorg Chem.
107(104549)2021.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Ramu A, Kathiresan S and Ali Ahmed B:
Gramine inhibits angiogenesis and induces apoptosis via modulation
of TGF-β signalling in 7,12 dimethylbenz[a]anthracene (DMBA)
induced hamster buccal pouch carcinoma. Phytomedicine. 33:69–76.
2017.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Ramu A, Kathiresan S, Ramadoss H, Nallu A,
Kaliyan R and Azamuthu T: Gramine attenuates EGFR-mediated
inflammation and cell proliferation in oral carcinogenesis via
regulation of NF-κB and STAT3 signaling. Biomed Pharmacother.
98:523–530. 2017.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Bayascas JR: PDK1: The major transducer of
PI 3-kinase actions. Curr Top Microbiol Immunol. 346:9–29.
2010.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Zheng NN, Wei JQ, Wu DP, Xu Y and Guo JP:
Master kinase PDK1 in tumorigenesis. Biochim Biophys Acta Rev
Cancer. 1878(188971)2023.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Wang JJ, Siu MK, Jiang YX, Leung TH, Chan
DW, Cheng RR, Cheung AN, Ngan HY and Chan KK: Aberrant upregulation
of PDK1 in ovarian cancer cells impairs CD8+ T cell
function and survival through elevation of PD-L1. Oncoimmunology.
8(e1659092)2019.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Zhang M, Cong Q, Zhang XY, Zhang MX, Lu YY
and Xu CJ: Pyruvate dehydrogenase kinase 1 contributes to cisplatin
resistance of ovarian cancer through EGFR activation. J Cell
Physiol. 234:6361–6370. 2019.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Altintas DM, Cerqua M, Comoglio PM and
Chaveroux C: The Janus framework of the integrated stress response:
From homeostasis to maladaptation. Life Sci Alliance.
9(e202503523)2025.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Lac V, Verhoef L, Aguirre-Hernandez R,
Nazeran TM, Tessier-Cloutier B, Praetorius T, Orr NL, Noga H, Lum
A, Khattra J, et al: Iatrogenic endometriosis harbors somatic
cancer-driver mutations. Hum Reprod. 34:69–78. 2019.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Cousin S, Grellety T, Toulmonde M,
Auzanneau C, Khalifa E, Laizet Y, Tran K, Le Moulec S, Floquet A,
Garbay D, et al: Clinical impact of extensive molecular profiling
in advanced cancer patients. J Hematol Oncol. 10(45)2017.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Yan T, Ma X, Guo L and Lu R: Targeting
endoplasmic reticulum stress signaling in ovarian cancer therapy.
Cancer Biol Med. 20:748–764. 2023.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Scheid MP, Marignani PA and Woodgett JR:
Multiple phosphoinositide 3-kinase-dependent steps in activation of
protein kinase B. Mol Cell Biol. 22:6247–6260. 2002.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Sarbassov DD, Guertin DA, Ali SM and
Sabatini DM: Phosphorylation and regulation of Akt/PKB by the
rictor-mTOR complex. Science. 307:1098–1101. 2005.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Liao Y and Hung MC: Physiological
regulation of Akt activity and stability. Am J Transl Res. 2:19–42.
2010.PubMed/NCBI
|
|
21
|
Duan J, Zhang Z, Du J, Zhang J, Li M and
Li C: Esomeprazole alleviates cisplatin resistance by inhibiting
the AKT/mTOR pathway in ovarian cancer cells. Onco Targets Ther.
16:425–440. 2023.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Zhang J, Jia Q, Li N, Gu L, Dan W and Dai
J: Recent developments of gramine: Chemistry and biological
activity. Molecules. 28(5695)2023.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Torri V, Harper PG, Colombo N, Sandercock
J and Parmar MK: Paclitaxel and cisplatin in ovarian cancer. J Clin
Oncol. 18:2349–2351. 2000.PubMed/NCBI
|
|
24
|
Skinner KT, Palkar AM and Hong AL:
Genetics of ABCB1 in cancer. Cancers (Basel).
15(4236)2023.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Yan X, Fraser M, Qiu Q and Tsang BK:
Over-expression of PTEN sensitizes human ovarian cancer cells to
cisplatin-induced apoptosis in a p53-dependent manner. Gynecol
Oncol. 102:348–355. 2006.PubMed/NCBI View Article : Google Scholar
|