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Anti-diabetic effects of fenugreek (Trigonella foenum-graecum): A comparison between oral and intraperitoneal administration - an animal study

  • Authors:
    • Marine E. Baset
    • Tasneem I. Ali
    • Hanan Elshamy
    • Ahmed M. El Sadek
    • Diana G. Sami
    • Marwa T. Badawy
    • Sara S. Abou-Zekry
    • Hana H. Heiba
    • Mona K. Saadeldin
    • Ahmed Abdellatif
  • View Affiliations / Copyright

    Affiliations: Faculty of Biotechnology, October University for Modern Sciences and Arts, 6th October City 12573, Egypt, Department of Biology, School of Sciences and Engineering, American University in Cairo, New Cairo 11835, Egypt
    Copyright: © Baset et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 2
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    Published online on: May 12, 2020
       https://doi.org/10.3892/ijfn.2020.2
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Abstract

Herbal medicine is used by millions of diabetic patients due to economic and cultural factors. The current study investigates the antidiabetic potential of fenugreek (Trigonella foenum-graecum) seed extract at a dose of 100 mg/kg in a Streptozocin-induced diabetic model. Male Sprague-Dawley rats received either intraperitoneal fenugreek [daily (ED) or every other day (EOD)] or oral fenugreek supplement daily, for four weeks. Results show that fenugreek significantly reduced blood glucose. Urea levels were reduced after daily intraperitoneal injection, and creatinine levels dropped after oral treatment, respectively. AST and ALT levels were reduced following fenugreek treatment, while protein levels significantly increased. High-density lipoprotein (HDL) increased after daily injections, while triglycerides decreased significantly in all groups. Glutathione S-transferase and catalase increased with treatment, while peroxidase antioxidant enzyme levels were reduced. Glutathione peroxidase levels increased only after daily injection. Histologically, fenugreek mildly protected hepatic, renal, and pancreatic tissues. In conclusion, the current study shows some potential benefits of fenugreek use. Oral and injectable fenugreek showed improvement in blood glucose, renal and liver functions. Although triglyceride levels decreased significantly, no significant changes in cholesterol levels were seen after fenugreek use. Higher doses and longer fenugreek treatment duration are recommended for the optimum protection of the liver, kidneys, and pancreatic tissues.
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1 

Ota A and Ulrih NP: An overview of herbal products and secondary metabolites used for management of type two diabetes. Front Pharmacol. 8(436)2017.PubMed/NCBI View Article : Google Scholar

2 

Choudhury H, Pandey M, Hua CK, Mun CS, Jing JK, Kong L, Ern LY, Ashraf NA, Kit SW, Yee TS, et al: An update on natural compounds in the remedy of diabetes mellitus: A systematic review. J Tradit Complement Med. 8:361–376. 2017.PubMed/NCBI View Article : Google Scholar

3 

Essa R, El Sadek AM, Baset ME, Rawash MA, Sami DG, Badawy MT, Mansour ME, Attia H, Saadeldin MK and Abdellatif A: Effects of turmeric (Curcuma longa) extract in streptozocin-induced diabetic model. J Food Biochem. 43(e12988)2019.PubMed/NCBI View Article : Google Scholar

4 

Bi X, Lim J and Henry CJ: Spices in the management of diabetes mellitus. Food Chem. 217:281–293. 2017.PubMed/NCBI View Article : Google Scholar

5 

Governa P, Baini G, Borgonetti V, Cettolin G, Giachetti D, Magnano AR, Miraldi E and Biagi M: Phytotherapy in the management of diabetes: A Review. Molecules. 23(E105)2018.PubMed/NCBI View Article : Google Scholar

6 

Adam SH, Giribabu N, Kassim N, Kumar KE, Brahmayya M, Arya A and Salleh N: Protective effect of aqueous seed extract of Vitis Vinifera against oxidative stress, inflammation and apoptosis in the pancreas of adult male rats with diabetes mellitus. Biomed Pharmacother. 81:439–452. 2016.PubMed/NCBI View Article : Google Scholar

7 

Deng R: A review of the hypoglycemic effects of five commonly used herbal food supplements. Recent Pat Food Nutr Agric. 4:50–60. 2012.PubMed/NCBI View Article : Google Scholar

8 

Medagama AB and Bandara R: The use of complementary and alternative medicines (CAMs) in the treatment of diabetes mellitus: Is continued use safe and effective? Nutr J. 13(102)2014.PubMed/NCBI View Article : Google Scholar

9 

Basch E, Ulbricht C, Kuo G, Szapary P and Smith M: Therapeutic applications of fenugreek. Altern Med Rev. 8:20–27. 2003.PubMed/NCBI

10 

Nagulapalli Venkata KC, Swaroop A, Bagchi D and Bishayee A: A small plant with big benefits: Fenugreek (Trigonella foenum-graecum Linn.) for disease prevention and health promotion. Mol Nutr Food Res. 61(1600950)2017.PubMed/NCBI View Article : Google Scholar

11 

Naicker N, Nagiah S, Phulukdaree A and Chuturgoon A: Trigonella foenum-graecum seed extract, 4-hydroxyisoleucine, and metformin stimulate proximal insulin signaling and increase expression of glycogenic enzymes and GLUT2 in HepG2 cells. Metab Syndr Relat Disord. 14:114–120. 2016.PubMed/NCBI View Article : Google Scholar

12 

Kumar A, Aswal S, Chauhan A, Semwal RB, Kumar A and Semwal DK: Ethnomedicinal investigation of medicinal plants of Chakrata region (Uttarakhand) used in the traditional medicine for diabetes by Jaunsari tribe. Nat Prod Bioprospect. 9:175–200. 2019.PubMed/NCBI View Article : Google Scholar

13 

Pradeep SR and Srinivasan K: Amelioration of hyperglycemia and associated metabolic abnormalities by a combination of fenugreek (Trigonella foenum-graecum) seeds and onion (Allium cepa) in experimental diabetes. J Basic Clin Physiol Pharmacol. 28:493–505. 2017.PubMed/NCBI View Article : Google Scholar

14 

Verma N, Usman K, Patel N, Jain A, Dhakre S, Swaroop A, Bagchi M, Kumar P, Preuss HG and Bagchi D: A multicenter clinical study to determine the efficacy of a novel fenugreek seed (Trigonella foenum-graecum) extract (Fenfuro™) in patients with type 2 diabetes. Food Nutr Res. 60(32382)2016.PubMed/NCBI View Article : Google Scholar

15 

Tomcik KA, Smiles WJ, Camera DM, Hügel HM, Hawley JA and Watts R: Fenugreek increases insulin-stimulated creatine content in L6C11 muscle myotubes. Eur J Nutr. 56:973–979. 2017.PubMed/NCBI View Article : Google Scholar

16 

Maritim AC, Sanders RA and Watkins JB III: Effects of alpha-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats. J Nutr Biochem. 14:288–294. 2003.PubMed/NCBI View Article : Google Scholar

17 

Aebi H: Catalase in vitro. Methods Enzymol. 105:121–126. 1984.PubMed/NCBI View Article : Google Scholar

18 

Paglia DE and Valentine WN: Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med. 70:158–169. 1967.PubMed/NCBI

19 

Habig WH, Pabst MJ, Fleischner G, Gatmaitan Z, Arias IM and Jakoby WB: The identity of glutathione S-transferase B with ligandin, a major binding protein of liver. Proc Natl Acad Sci USA. 71:3879–3882. 1974.PubMed/NCBI View Article : Google Scholar

20 

Vetter HF and Vullers R: Effectiveness of enzyme substitution with pancynorm in chronic gastroduodenitis. Munch Med Wochenschr. 100:1786–1787. 1958.(In German). PubMed/NCBI

21 

Szkudelski T: The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Res. 50:537–546. 2001.PubMed/NCBI

22 

Lenzen S: The mechanisms of alloxan- and streptozotocin-induced diabetes. Diabetologia. 51:216–226. 2008.PubMed/NCBI View Article : Google Scholar

23 

Ozkol H, Tuluce Y, Dilsiz N and Koyuncu I: Therapeutic potential of some plant extracts used in Turkish traditional medicine on streptozocin-induced type 1 diabetes mellitus in rats. J Membr Biol. 246:47–55. 2013.PubMed/NCBI View Article : Google Scholar

24 

Little RR and Roberts WL: A review of variant hemoglobins interfering with hemoglobin A1c measurement. J Diabetes Sci Technol. 3:446–451. 2009.PubMed/NCBI View Article : Google Scholar

25 

Little RR and Sacks DB: HbA1c: How do we measure it and what does it mean? Curr Opin Endocrinol Diabetes Obes. 16:113–118. 2009.PubMed/NCBI View Article : Google Scholar

26 

Pundir CS and Chawla S: Determination of glycated hemoglobin with special emphasis on biosensing methods. Anal Biochem. 444:47–56. 2014.PubMed/NCBI View Article : Google Scholar

27 

Haeri MR, Limaki HK, White CJ and White KN: Non-insulin dependent anti-diabetic activity of (2S, 3R, 4S) 4-hydroxyisoleucine of fenugreek (Trigonella foenum graecum) in streptozotocin-induced type I diabetic rats. Phytomedicine. 19:571–574. 2012.PubMed/NCBI View Article : Google Scholar

28 

Puri D, Prabhu KM and Murthy PS: Mechanism of action of a hypoglycemic principle isolated from fenugreek seeds. Indian J Physiol Pharmacol. 46:457–462. 2002.PubMed/NCBI

29 

Murao K, Yu X, Imachi H, Cao WM, Chen K, Matsumoto K, Nishiuchi T, Wong NC and Ishida T: Hyperglycemia suppresses hepatic scavenger receptor class B type I expression. Am J Physiol Endocrinol Metab. 294:E78–E87. 2008.PubMed/NCBI View Article : Google Scholar

30 

Noor Mohamad Zin NS, Hashim N, Samsulrizal N and Azmi NS: The protective effect of Azadirachta excelsa leaves extract and quercetin treatment on the learning and memory impairments in relation with insulin and amylin levels in the brain of streptozotocin-induced diabetic rats. J King Saud Univ Sci. 31:299–307. 2019.https://doi.org/10.1016/j.jksus.2018.05.017.

31 

Kalailingam P, Kannaian B, Tamilmani E and Kaliaperumal R: Efficacy of natural diosgenin on cardiovascular risk, insulin secretion, and beta cells in streptozotocin (STZ)-induced diabetic rats. Phytomedicine. 21:1154–1161. 2014.PubMed/NCBI View Article : Google Scholar

32 

Hamden K, Jaouadi B, Carreau S, Aouidet A, El-Fazaa S, Gharbi N and Elfeki A: Potential protective effect on key steroidogenesis and metabolic enzymes and sperm abnormalities by fenugreek steroids in testis and epididymis of surviving diabetic rats. Arch Physiol Biochem. 116:146–155. 2010.PubMed/NCBI View Article : Google Scholar

33 

Jin Y, Shi Y, Zou Y, Miao C, Sun B and Li C: Fenugreek prevents the development of STZ-induced diabetic nephropathy in a rat model of diabetes. Evid Based Complement Alternat Med. 2014(259368)2014.PubMed/NCBI View Article : Google Scholar

34 

Xue WL, Li XS, Zhang J, Liu YH, Wang ZL and Zhang RJ: Effect of Trigonella foenum-graecum (fenugreek) extract on blood glucose, blood lipid and hemorheological properties in streptozotocin-induced diabetic rats. Asia Pac J Clin Nutr. 16 (Suppl 1):422–426. 2007.PubMed/NCBI

35 

Xue W, Lei J, Li X and Zhang R: Trigonella foenum graecum seed extract protects kidney function and morphology in diabetic rats via its antioxidant activity. Nutr Res. 31:555–562. 2011.PubMed/NCBI View Article : Google Scholar

36 

Jiang W, Gao L, Li P, Kan H, Qu J, Men L and Liu Z and Liu Z: Metabonomics study of the therapeutic mechanism of fenugreek galactomannan on diabetic hyperglycemia in rats, by ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 1044-1045:8–16. 2017.PubMed/NCBI View Article : Google Scholar

37 

Jiang W, Si L, Li P, Bai B, Qu J, Hou B, Zou H, Fan X, Liu Z, Liu Z, et al: Serum metabonomics study on antidiabetic effects of fenugreek flavonoids in streptozotocin-induced rats. J Chromatogr B Analyt Technol Biomed Life Sci. 1092:466–472. 2018.PubMed/NCBI View Article : Google Scholar

38 

Brent JA and Rumack BH: Role of free radicals in toxic hepatic injury. II. Are free radicals the cause of toxin-induced liver injury? J Toxicol Clin Toxicol. 31:173–196. 1993.PubMed/NCBI View Article : Google Scholar

39 

Elmnan A, Balgees A and Mangara JL: Effect of fenugreek (Trigonella foenm greacum) seed dietary levels on lipid profile and body weight gain of rats. Pak J Nutr. 11:1004–1008. 2012.

40 

Garcia TS, Rech TH and Leitão CB: Pancreatic volume in diabetes mellitus. Pancreas. 46(e51)2017.PubMed/NCBI View Article : Google Scholar

41 

Garcia TS, Rech TH and Leitão CB: Pancreatic size and fat content in diabetes: A systematic review and meta-analysis of imaging studies. PLoS One. 12(e0180911)2017.PubMed/NCBI View Article : Google Scholar

42 

Raju J and Bird RP: Alleviation of hepatic steatosis accompanied by modulation of plasma and liver TNF-alpha levels by Trigonella foenum graecum (fenugreek) seeds in Zucker obese (fa/fa) rats. Int J Obes. 30:1298–1307. 2006.PubMed/NCBI View Article : Google Scholar

43 

Sushma N and Devasena T: Aqueous extract of Trigonella foenum graecum (fenugreek) prevents cypermethrin-induced hepatotoxicity and nephrotoxicity. Hum Exp Toxicol. 29:311–319. 2010.PubMed/NCBI View Article : Google Scholar

44 

Sharma MS and Choudhary PR: Hypolipidemic effect of fenugreek seeds and its comparison with atorvastatin on experimentally induced hyperlipidemia. J Coll Physicians Surg Pak. 24:539–542. 2014.PubMed/NCBI

45 

Marzouk M, Soliman AM and Omar TY: Hypoglycemic and antioxidative effects of fenugreek and termis seeds powder in streptozotocin-diabetic rats. Eur Rev Med Pharmacol Sci. 17:559–565. 2013.PubMed/NCBI

46 

Shivakumar A, Jashmitha BG and Dhruvaraj MR: Role of peroxidase in clinical assays: A short review. J Clin Nutr Diet. 3(2)2017.https://doi.org/10.4172/2472-1921.100048.

47 

Gaddam A, Galla C, Thummisetti S, Marikanty RK, Palanisamy UD and Rao PV: Role of fenugreek in the prevention of type 2 diabetes mellitus in prediabetes. J Diabetes Metab Disord. 14(74)2015.PubMed/NCBI View Article : Google Scholar

48 

Herrera T, Navarro Del Hierro J, Fornari T, Reglero G and Martin D: Acid hydrolysis of saponin-rich extracts of quinoa, lentil, fenugreek and soybean to yield sapogenin-rich extracts and other bioactive compounds. J Sci Food Agric. 99:3157–3167. 2019.PubMed/NCBI View Article : Google Scholar

49 

Srinivasan K: Plant foods in the management of diabetes mellitus: Spices as beneficial antidiabetic food adjuncts. Int J Food Sci Nutr. 56:399–414. 2005.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Baset ME, Ali TI, Elshamy H, El Sadek AM, Sami DG, Badawy MT, Abou-Zekry SS, Heiba HH, Saadeldin MK, Abdellatif A, Abdellatif A, et al: Anti-diabetic effects of fenugreek (Trigonella foenum-graecum): A comparison between oral and intraperitoneal administration - an animal study. Int J Funct Nutr 1: 2, 2020.
APA
Baset, M.E., Ali, T.I., Elshamy, H., El Sadek, A.M., Sami, D.G., Badawy, M.T. ... Abdellatif, A. (2020). Anti-diabetic effects of fenugreek (Trigonella foenum-graecum): A comparison between oral and intraperitoneal administration - an animal study. International Journal of Functional Nutrition, 1, 2. https://doi.org/10.3892/ijfn.2020.2
MLA
Baset, M. E., Ali, T. I., Elshamy, H., El Sadek, A. M., Sami, D. G., Badawy, M. T., Abou-Zekry, S. S., Heiba, H. H., Saadeldin, M. K., Abdellatif, A."Anti-diabetic effects of fenugreek (Trigonella foenum-graecum): A comparison between oral and intraperitoneal administration - an animal study". International Journal of Functional Nutrition 1.1 (2020): 2.
Chicago
Baset, M. E., Ali, T. I., Elshamy, H., El Sadek, A. M., Sami, D. G., Badawy, M. T., Abou-Zekry, S. S., Heiba, H. H., Saadeldin, M. K., Abdellatif, A."Anti-diabetic effects of fenugreek (Trigonella foenum-graecum): A comparison between oral and intraperitoneal administration - an animal study". International Journal of Functional Nutrition 1, no. 1 (2020): 2. https://doi.org/10.3892/ijfn.2020.2
Copy and paste a formatted citation
x
Spandidos Publications style
Baset ME, Ali TI, Elshamy H, El Sadek AM, Sami DG, Badawy MT, Abou-Zekry SS, Heiba HH, Saadeldin MK, Abdellatif A, Abdellatif A, et al: Anti-diabetic effects of fenugreek (Trigonella foenum-graecum): A comparison between oral and intraperitoneal administration - an animal study. Int J Funct Nutr 1: 2, 2020.
APA
Baset, M.E., Ali, T.I., Elshamy, H., El Sadek, A.M., Sami, D.G., Badawy, M.T. ... Abdellatif, A. (2020). Anti-diabetic effects of fenugreek (Trigonella foenum-graecum): A comparison between oral and intraperitoneal administration - an animal study. International Journal of Functional Nutrition, 1, 2. https://doi.org/10.3892/ijfn.2020.2
MLA
Baset, M. E., Ali, T. I., Elshamy, H., El Sadek, A. M., Sami, D. G., Badawy, M. T., Abou-Zekry, S. S., Heiba, H. H., Saadeldin, M. K., Abdellatif, A."Anti-diabetic effects of fenugreek (Trigonella foenum-graecum): A comparison between oral and intraperitoneal administration - an animal study". International Journal of Functional Nutrition 1.1 (2020): 2.
Chicago
Baset, M. E., Ali, T. I., Elshamy, H., El Sadek, A. M., Sami, D. G., Badawy, M. T., Abou-Zekry, S. S., Heiba, H. H., Saadeldin, M. K., Abdellatif, A."Anti-diabetic effects of fenugreek (Trigonella foenum-graecum): A comparison between oral and intraperitoneal administration - an animal study". International Journal of Functional Nutrition 1, no. 1 (2020): 2. https://doi.org/10.3892/ijfn.2020.2
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