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Pharmacology and ethnobotany of Vetiveria zizanioides and integration of its traditional uses with modern therapeutic applications: A scoping review

  • Authors:
    • Soham Apte
    • Zachary Dyer
    • Ashlyn Dull
    • Muhammad Nabeel Ghayur
  • View Affiliations / Copyright

    Affiliations: Kentucky College of Osteopathic Medicine, University of Pikeville, Pikeville, KY 41501, USA
    Copyright: © Apte et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 2
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    Published online on: March 12, 2026
       https://doi.org/10.3892/ijfn.2026.54
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Abstract

Vetiveria zizanioides (L.) Nash, commonly known as vetiver, is a plant with a rich history in ancient medicine, particularly in Ayurveda, where it continues to be used for its numerous medicinal properties. Traditionally, vetiver roots and leaves have been used to treat conditions such as burns, convulsions, urinary tract infections and gastrointestinal issues, while also serving as an aromatic component in various healing products. Despite thousands of years of extensive experimental trial‑and‑error and subsequent prolonged applications, modern scientific research has only recently begun to uncover the pharmacological potential of vetiver, revealing potential qualities such as its anticonvulsant, antioxidant, anti‑tuberculosis, antifungal, cytotoxic and antimicrobial activities. The present scoping review explores the numerous aspects of the traditional uses of vetiver with its emerging pharmaceutical applications, emphasizing the importance of integrating traditional, herbal medicinal knowledge with contemporary scientific methodologies. The understanding of the mechanisms underlying the effects of vetiver on inflammation and related diseases, and uncovering how it was utilized historically within Ayurvedic/traditional practices, can pave the way for its broader utilization in modern medicine.
View Figures

Figure 1

Image illustrating Vetiveria
zizanioides (L.) Nash, also known as vetiver and khus grass; a
perennial bunchgrass from Poaceae family (image taken by the
author, MNG).

Figure 2

Map of the Indian Subcontinent
illustrating the location of the Western Ghats Mountain Range, also
known as Sahyadri, where vetiver or khus grass abundantly grows.
The Western Ghats are spread over a number of provinces in India,
such as, Gujarat, Maharashtra, Goa, Karnataka, Kerala, and Tamil
Nadu (empty map obtained from a free internet resource, www.deviantart.com; then redesigned with text and
color by the author, MNG).

Figure 3

Chemical structures of some of the
bioactive compounds in Vetiveria zizanioides (chemical
structures taken from: https://webbook.nist.gov/chemistry/).
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Spandidos Publications style
Apte S, Dyer Z, Dull A and Ghayur MN: Pharmacology and ethnobotany of <em>Vetiveria zizanioides</em> and integration of its traditional uses with modern therapeutic applications: A scoping review. Int J Funct Nutr 7: 2, 2026.
APA
Apte, S., Dyer, Z., Dull, A., & Ghayur, M.N. (2026). Pharmacology and ethnobotany of <em>Vetiveria zizanioides</em> and integration of its traditional uses with modern therapeutic applications: A scoping review. International Journal of Functional Nutrition, 7, 2. https://doi.org/10.3892/ijfn.2026.54
MLA
Apte, S., Dyer, Z., Dull, A., Ghayur, M. N."Pharmacology and ethnobotany of <em>Vetiveria zizanioides</em> and integration of its traditional uses with modern therapeutic applications: A scoping review". International Journal of Functional Nutrition 7.1 (2026): 2.
Chicago
Apte, S., Dyer, Z., Dull, A., Ghayur, M. N."Pharmacology and ethnobotany of <em>Vetiveria zizanioides</em> and integration of its traditional uses with modern therapeutic applications: A scoping review". International Journal of Functional Nutrition 7, no. 1 (2026): 2. https://doi.org/10.3892/ijfn.2026.54
Copy and paste a formatted citation
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Spandidos Publications style
Apte S, Dyer Z, Dull A and Ghayur MN: Pharmacology and ethnobotany of <em>Vetiveria zizanioides</em> and integration of its traditional uses with modern therapeutic applications: A scoping review. Int J Funct Nutr 7: 2, 2026.
APA
Apte, S., Dyer, Z., Dull, A., & Ghayur, M.N. (2026). Pharmacology and ethnobotany of <em>Vetiveria zizanioides</em> and integration of its traditional uses with modern therapeutic applications: A scoping review. International Journal of Functional Nutrition, 7, 2. https://doi.org/10.3892/ijfn.2026.54
MLA
Apte, S., Dyer, Z., Dull, A., Ghayur, M. N."Pharmacology and ethnobotany of <em>Vetiveria zizanioides</em> and integration of its traditional uses with modern therapeutic applications: A scoping review". International Journal of Functional Nutrition 7.1 (2026): 2.
Chicago
Apte, S., Dyer, Z., Dull, A., Ghayur, M. N."Pharmacology and ethnobotany of <em>Vetiveria zizanioides</em> and integration of its traditional uses with modern therapeutic applications: A scoping review". International Journal of Functional Nutrition 7, no. 1 (2026): 2. https://doi.org/10.3892/ijfn.2026.54
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