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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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March 2005 Volume 15 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

Protective effects of a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3F1 mice: Increased small intestinal crypt survival and prolongation of average time to animal death

  • Authors:
    • Nanami Kubo
    • Yuki Myojin
    • Fumio Shimamoto
    • Naoki Kashimoto
    • Eikai Kyo
    • Kenji Kamiya
    • Hiromitsu Watanabe

  • View Affiliations / Copyright

    Affiliations: Department of Health Science, Hiroshima Prefectural Women's University, Minami-ku, Hiroshima 734-8558, Japan
  • Pages: 401-406
    |
    Published online on: March 1, 2005
       https://doi.org/10.3892/ijmm.15.3.401
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Abstract

Radioprotective effects of a water-soluble extracts from cultured medium of Ganoderma lucidum (Rei-shi) mycelia (designed as MAK) and Agaricus blazei (Agaricus) against the shortening of survival time or the injury of crypt by X-irradiation were investigated in male B6C3F1 mice. MAK and Agaricus at three different doses were mixed into basal diet into biscuits at 5, 2.5 and 1.25% and administered from 1 week before irradiation. MAK (5% group) significantly prolonged animal survival as compared with basal diet group (control group) after 7 Gy of X-ray irradiation at a dose rate of 2 Gy min−1. At doses of 8, 10 and 12 Gy X-irradiation at a dose rate of 4 Gy min−1 MAK (5% group) significantly increased crypt survival as compared to other groups. These results suggest that MAK can act as a radioprotective agent.

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Copy and paste a formatted citation
Spandidos Publications style
Kubo N, Myojin Y, Shimamoto F, Kashimoto N, Kyo E, Kamiya K and Watanabe H: Protective effects of a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3F1 mice: Increased small intestinal crypt survival and prolongation of average time to animal death. Int J Mol Med 15: 401-406, 2005.
APA
Kubo, N., Myojin, Y., Shimamoto, F., Kashimoto, N., Kyo, E., Kamiya, K., & Watanabe, H. (2005). Protective effects of a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3F1 mice: Increased small intestinal crypt survival and prolongation of average time to animal death. International Journal of Molecular Medicine, 15, 401-406. https://doi.org/10.3892/ijmm.15.3.401
MLA
Kubo, N., Myojin, Y., Shimamoto, F., Kashimoto, N., Kyo, E., Kamiya, K., Watanabe, H."Protective effects of a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3F1 mice: Increased small intestinal crypt survival and prolongation of average time to animal death". International Journal of Molecular Medicine 15.3 (2005): 401-406.
Chicago
Kubo, N., Myojin, Y., Shimamoto, F., Kashimoto, N., Kyo, E., Kamiya, K., Watanabe, H."Protective effects of a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3F1 mice: Increased small intestinal crypt survival and prolongation of average time to animal death". International Journal of Molecular Medicine 15, no. 3 (2005): 401-406. https://doi.org/10.3892/ijmm.15.3.401
Copy and paste a formatted citation
x
Spandidos Publications style
Kubo N, Myojin Y, Shimamoto F, Kashimoto N, Kyo E, Kamiya K and Watanabe H: Protective effects of a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3F1 mice: Increased small intestinal crypt survival and prolongation of average time to animal death. Int J Mol Med 15: 401-406, 2005.
APA
Kubo, N., Myojin, Y., Shimamoto, F., Kashimoto, N., Kyo, E., Kamiya, K., & Watanabe, H. (2005). Protective effects of a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3F1 mice: Increased small intestinal crypt survival and prolongation of average time to animal death. International Journal of Molecular Medicine, 15, 401-406. https://doi.org/10.3892/ijmm.15.3.401
MLA
Kubo, N., Myojin, Y., Shimamoto, F., Kashimoto, N., Kyo, E., Kamiya, K., Watanabe, H."Protective effects of a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3F1 mice: Increased small intestinal crypt survival and prolongation of average time to animal death". International Journal of Molecular Medicine 15.3 (2005): 401-406.
Chicago
Kubo, N., Myojin, Y., Shimamoto, F., Kashimoto, N., Kyo, E., Kamiya, K., Watanabe, H."Protective effects of a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3F1 mice: Increased small intestinal crypt survival and prolongation of average time to animal death". International Journal of Molecular Medicine 15, no. 3 (2005): 401-406. https://doi.org/10.3892/ijmm.15.3.401
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