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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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August 2005 Volume 16 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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August 2005 Volume 16 Issue 2

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Article

A very short segment of the murine Ret promoter contains elements sensitive to in vitro neural cell differentiation

  • Authors:
    • Paola Zordan
    • Roberto Ravazzolo
    • Renata Bocciardi
  • View Affiliations / Copyright

    Affiliations: Laboratory of Molecular Genetics, G. Gaslini Institute, Largo G. Gaslini 5, 16147 Genova, Italy
  • Pages: 325-331
    |
    Published online on: August 1, 2005
       https://doi.org/10.3892/ijmm.16.2.325
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Abstract

Regulation of the murine Ret gene has only been partially studied, specifically cis-acting promoter elements and related transcription factors, although in vivo experiments have shown the ability of Ret 5' flanking sequences to drive expression of transgenic reporter genes. This work describes the characterization of a 387-bp fragment of the Ret 5' flanking sequence with the ability to activate expression of the LacZ gene in transfected cells, in which SP1 recognition elements played a fundamental role. Using P19 teratocarcinoma cells differentiated by retinoic acid treatment, we observed an induction of Ret mRNA accompanied by a decrease of SP1 binding due to its proteolytic cleavage.

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Copy and paste a formatted citation
Spandidos Publications style
Zordan P, Ravazzolo R and Bocciardi R: A very short segment of the murine Ret promoter contains elements sensitive to in vitro neural cell differentiation. Int J Mol Med 16: 325-331, 2005.
APA
Zordan, P., Ravazzolo, R., & Bocciardi, R. (2005). A very short segment of the murine Ret promoter contains elements sensitive to in vitro neural cell differentiation. International Journal of Molecular Medicine, 16, 325-331. https://doi.org/10.3892/ijmm.16.2.325
MLA
Zordan, P., Ravazzolo, R., Bocciardi, R."A very short segment of the murine Ret promoter contains elements sensitive to in vitro neural cell differentiation". International Journal of Molecular Medicine 16.2 (2005): 325-331.
Chicago
Zordan, P., Ravazzolo, R., Bocciardi, R."A very short segment of the murine Ret promoter contains elements sensitive to in vitro neural cell differentiation". International Journal of Molecular Medicine 16, no. 2 (2005): 325-331. https://doi.org/10.3892/ijmm.16.2.325
Copy and paste a formatted citation
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Spandidos Publications style
Zordan P, Ravazzolo R and Bocciardi R: A very short segment of the murine Ret promoter contains elements sensitive to in vitro neural cell differentiation. Int J Mol Med 16: 325-331, 2005.
APA
Zordan, P., Ravazzolo, R., & Bocciardi, R. (2005). A very short segment of the murine Ret promoter contains elements sensitive to in vitro neural cell differentiation. International Journal of Molecular Medicine, 16, 325-331. https://doi.org/10.3892/ijmm.16.2.325
MLA
Zordan, P., Ravazzolo, R., Bocciardi, R."A very short segment of the murine Ret promoter contains elements sensitive to in vitro neural cell differentiation". International Journal of Molecular Medicine 16.2 (2005): 325-331.
Chicago
Zordan, P., Ravazzolo, R., Bocciardi, R."A very short segment of the murine Ret promoter contains elements sensitive to in vitro neural cell differentiation". International Journal of Molecular Medicine 16, no. 2 (2005): 325-331. https://doi.org/10.3892/ijmm.16.2.325
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