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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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June 2006 Volume 17 Issue 6

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Medicine International

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Article

Urotensin-II and UII-receptor expression and function in the rat adrenal cortex

  • Authors:
    • Giovanna Albertin
    • Valentina Casale
    • Agnieszka Ziolkowska
    • Raffaella Spinazzi
    • Ludwik K. Malendowicz
    • Gian Paolo Rossi
    • Gastone G. Nussdorfer
  • View Affiliations / Copyright

    Affiliations: Department of Human Anatomy and Physiology, Section of Anatomy, School of Medicine, University of Padua, I-35121 Padua, Italy
  • Pages: 1111-1115
    |
    Published online on: June 1, 2006
       https://doi.org/10.3892/ijmm.17.6.1111
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Abstract

Urotensin-II (UII) is a potent hypertensive peptide, which has been recognized as an endogenous ligand of the G protein-coupled receptor (GPR)-14, now named UT-R. Real-time PCR demonstrated the expression of UII and UT-R mRNAs in both dispersed and in vitro cultured rat adrenocortical cells. UII concentration-dependently decreased basal, but not ACTH-stimulated, corticosterone secretion from cultured adrenocortical cells, and the effect was abolished by the UT-R antagonist Palosuran. UII did not affect the proliferation rate of cultured cells. Taken together, these findings suggest that UII may be included in the group of peptides (adrenomedullin, atrial natriuretic peptide, neurotensin and beacon), that, acting in an autocrine-paracrine manner, are involved in the inhibitory tuning of adrenocortical secretion.

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Copy and paste a formatted citation
Spandidos Publications style
Albertin G, Casale V, Ziolkowska A, Spinazzi R, Malendowicz LK, Rossi GP and Nussdorfer GG: Urotensin-II and UII-receptor expression and function in the rat adrenal cortex. Int J Mol Med 17: 1111-1115, 2006.
APA
Albertin, G., Casale, V., Ziolkowska, A., Spinazzi, R., Malendowicz, L.K., Rossi, G.P., & Nussdorfer, G.G. (2006). Urotensin-II and UII-receptor expression and function in the rat adrenal cortex. International Journal of Molecular Medicine, 17, 1111-1115. https://doi.org/10.3892/ijmm.17.6.1111
MLA
Albertin, G., Casale, V., Ziolkowska, A., Spinazzi, R., Malendowicz, L. K., Rossi, G. P., Nussdorfer, G. G."Urotensin-II and UII-receptor expression and function in the rat adrenal cortex". International Journal of Molecular Medicine 17.6 (2006): 1111-1115.
Chicago
Albertin, G., Casale, V., Ziolkowska, A., Spinazzi, R., Malendowicz, L. K., Rossi, G. P., Nussdorfer, G. G."Urotensin-II and UII-receptor expression and function in the rat adrenal cortex". International Journal of Molecular Medicine 17, no. 6 (2006): 1111-1115. https://doi.org/10.3892/ijmm.17.6.1111
Copy and paste a formatted citation
x
Spandidos Publications style
Albertin G, Casale V, Ziolkowska A, Spinazzi R, Malendowicz LK, Rossi GP and Nussdorfer GG: Urotensin-II and UII-receptor expression and function in the rat adrenal cortex. Int J Mol Med 17: 1111-1115, 2006.
APA
Albertin, G., Casale, V., Ziolkowska, A., Spinazzi, R., Malendowicz, L.K., Rossi, G.P., & Nussdorfer, G.G. (2006). Urotensin-II and UII-receptor expression and function in the rat adrenal cortex. International Journal of Molecular Medicine, 17, 1111-1115. https://doi.org/10.3892/ijmm.17.6.1111
MLA
Albertin, G., Casale, V., Ziolkowska, A., Spinazzi, R., Malendowicz, L. K., Rossi, G. P., Nussdorfer, G. G."Urotensin-II and UII-receptor expression and function in the rat adrenal cortex". International Journal of Molecular Medicine 17.6 (2006): 1111-1115.
Chicago
Albertin, G., Casale, V., Ziolkowska, A., Spinazzi, R., Malendowicz, L. K., Rossi, G. P., Nussdorfer, G. G."Urotensin-II and UII-receptor expression and function in the rat adrenal cortex". International Journal of Molecular Medicine 17, no. 6 (2006): 1111-1115. https://doi.org/10.3892/ijmm.17.6.1111
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