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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2006 Volume 17 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Current bioinformatics tools in genomic biomedical research (Review)

Andreas Teufel, Markus Krupp, Arndt Weinmann, Peter R. Galle
Pages: 967-973
Published online on: 01 June 2006

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Article

Adiponectin receptor expression in the human adrenal cortex and aldosterone-producing adenomas

Gian Paolo Rossi, Daniele Sticchi, Luisa Giuliani, Paolo Bernante, Silvia Zavattiero, Achille C. Pessina, Gastone G. Nussdorfer
Pages: 975-980
Published online on: 01 June 2006

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Article

An image analysis of the spatial distribution of perivascular mast cells in human melanoma

Diego Guidolin, Enrico Crivellato, Beatrice Nico, Paola G. Andreis, Gastone G. Nussdorfer, Domenico Ribatti
Pages: 981-987
Published online on: 01 June 2006

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Article

Expression of thioredoxin and thioredoxin-binding protein-2 in the liver of patients with chronic hepatitis C as a predictor of response to interferon therapy

Kenichi Hamano, Yasushi Seo, Hirotaka Kato, Miyuki Kato, Yoshihiko Yano, Toshiaki Ninomiya, Masato Kasuga
Pages: 989-995
Published online on: 01 June 2006

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Article

Rosuvastatin, a new HMG-CoA reductase inhibitor, reduces the colonic inflammatory response in dextran sulfate sodium-induced colitis in mice

Yuji Naito, Kazuhiro Katada, Tomohisa Takagi, Hisato Tsuboi, Yutaka Isozaki, Osamu Handa, Satoshi Kokura, Norimasa Yoshida, Hiroshi Ichikawa, Toshikazu Yoshikawa
Pages: 997-1004
Published online on: 01 June 2006

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Article

Polysiphonia japonica extract suppresses the Wnt/β-catenin pathway in colon cancer cells by activation of NF-κB

Jungsug Gwak, Seoyoung Park, Munju Cho, Taeyun Song, Seon-Heui Cha, Dong-Eun Kim, You-Jin Jeon, Jae-Gook Shin, Sangtaek Oh
Pages: 1005-1010
Published online on: 01 June 2006

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Article

Method for efficient transfection of in vitro-transcribed mRNA into SK-N-AS and HEK293 cells: Difference in the toxicity of nuclear EGFP compared to cytoplasmic EGFP

Katarina Ejeskär, Susanne Fransson, Faten Zaibak, Panayiotis A. Ioannou
Pages: 1011-1016
Published online on: 01 June 2006

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Article

Growth promoting in vitro effect of synthetic cyclic RGD-peptides on human osteoblast-like cells attached to cancellous bone

Ursula Magdolen, Jörg Auernheimer, Claudia Dahmen, Johannes Schauwecker, Hans Gollwitzer, Jutta Tübel, Reiner Gradinger, Horst Kessler, Manfred Schmitt, Peter Diehl
Pages: 1017-1021
Published online on: 01 June 2006

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Article

A novel MLH1 mutation harbored as a germ line aberration by a young woman of an HNPCC-like family and exhibited by a CML patient when occurring prior to the initiation of the blast phase concomitant with a c-MYC amplification

Dorit Amikam, Lucy Leshanski, Michal Sagi
Pages: 1023-1026
Published online on: 01 June 2006

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Article

The differential expression of SPARC in esophageal squamous cell carcinoma

Yiqun Che, Aiping Luo, Hai Wang, Jun Qi, Jian Guo, Zhihua Liu
Pages: 1027-1033
Published online on: 01 June 2006

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Article

Altered calcium handling is an early sign of streptozotocin-induced diabetic cardiomyopathy

László Ligeti, Orsolya Szenczi, Christina M. Prestia, Csaba Szabó, Katalin Horváth, Zoltán L. Marcsek, Ruud G.P.M. Van Stiphout, Natal A.W. Van Riel, Jorn Op Den Buijs, Ger J. Van der Vusse, Tamás Ivanics
Pages: 1035-1043
Published online on: 01 June 2006

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Article

Evaluating strategies to enhance the anti-tumor immune response to a carbohydrate mimetic peptide vaccine

Behjatolah Monzavi-Karbassi, Anastas Pashov, Fariba Jousheghany, Cecile Artaud, Thomas Kieber-Emmons
Pages: 1045-1052
Published online on: 01 June 2006

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Article

57Arg in the bHLH transcription factor DEC2 is essential for the suppression of CLOCK/BMAL2-mediated transactivation

Jun Kondo, Fuyuki Sato, Katsumi Fujimoto, Tomomi Kusumi, Tadanobu Imanaka, Takeshi Kawamoto, Bhawal Uk, Mitsuhide Noshiro, Yukio Kato, Tatsusuke Sato, Hiroshi Kijima
Pages: 1053-1056
Published online on: 01 June 2006

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Article

hCAR-EGFP fusion receptor in human follicular lymphoma B cells - A model for adenoviral gene therapy for B cell malignancies

Mikko Mättö, Ulla-Maija Nuutinen, Tanja Hakkarainen, Tiziano Tallone, Jarmo Wahlfors, Jukka Pelkonen
Pages: 1057-1062
Published online on: 01 June 2006

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Article

Hepatocyte ‘priming’ and increase in transforming growth factor-β1 mRNA expression are delayed in hypothyroid versus euthyroid rats during liver regeneration

Loredana Moro, Elda Perlino, Ersilia Marra, Margherita Greco
Pages: 1063-1068
Published online on: 01 June 2006

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Article

Resveratrol inhibits inducible nitric oxide synthase and cyclooxygenase-2 expression in β-amyloid-treated C6 glioma cells

Young Ae Kim, Sun-Young Lim, Sook-Hee Rhee, Kun Young Park, Cheorl-Ho Kim, Byung Tae Choi, Su Jae Lee, Yeong-Min Park, Yung Hyun Choi
Pages: 1069-1075
Published online on: 01 June 2006

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Article

Creatine supplementation increases soleus muscle creatine content and lowers the insulinogenic index in an animal model of inherited type 2 diabetes

Bert Op't Eijnde, Hassan Jijakli, Peter Hespel, Willy J. Malaisse
Pages: 1077-1084
Published online on: 01 June 2006

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Article

Molecular basis for the involvement of thymidine phosphorylase in cancer invasion

Takenari Gotanda, Misako Haraguchi, Tokushi Tachiwada, Reiko Shinkura, Chihaya Koriyama, Suminori Akiba, Motoshi Kawahara, Kenryu Nishiyama, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Hiromitsu Mimata, Yoshio Nomura, Shin-ichi Akiyama, Masayuki Nakagawa
Pages: 1085-1091
Published online on: 01 June 2006

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Article

Human membrane protein Tim-3 facilitates hepatitis A virus entry into target cells

Lili Sui, Nan Li, Wenyuan Zhang, Yong Chen, Yuanyuan Zheng, Tao Wan, Weiping Zhang, Yadong Yang, Guojian Fang, Jiangsen Mao, Xuetao Cao
Pages: 1093-1099
Published online on: 01 June 2006

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Article

In vitro culture on Matrigel favors the long-term maintenance of rat zona glomerulosa-cell differentiated phenotype

Raffaella Spinazzi, Lucia Petrelli, Diego Guidolin, Gianni Carraro, Valentina Casale, Cinzia Tortorella, Giuliano Neri, Giovanna Albertin, Paola G. Andreis, Gastone G. Nussdorfer
Pages: 1101-1110
Published online on: 01 June 2006

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Article

Urotensin-II and UII-receptor expression and function in the rat adrenal cortex

Giovanna Albertin, Valentina Casale, Agnieszka Ziolkowska, Raffaella Spinazzi, Ludwik K. Malendowicz, Gian Paolo Rossi, Gastone G. Nussdorfer
Pages: 1111-1115
Published online on: 01 June 2006

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Article

Characterization of a novel human protein phosphatase 2C family member, PP2Cκ

Jianfeng Dai, Jiyuan Zhang, Yaqiong Sun, Qihan Wu, Liyun Sun, Chaoneng Ji, Shaohua Gu, Congjing Feng, Yi Xie, Yumin Mao
Pages: 1117-1123
Published online on: 01 June 2006

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Article

The expression profile of PKC isoforms during MC3T3-E1 differentiation

J. D. Lampasso, Wen Chen, N. Marzec
Pages: 1125-1131
Published online on: 01 June 2006

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Article

Effect of GLP-1 on D-glucose transport, lipolysis and lipogenesis in adipocytes of obese subjects

Verónica Sancho, María V. Trigo, Antonio Martín-Duce, Nieves González, Alicia Acitores, Luis Arnés, Isabel Valverde, Willy J. Malaisse, María L. Villanueva-Peñacarrillo
Pages: 1133-1137
Published online on: 01 June 2006

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Article

Desflurane differentially affects the release of proinflammatory cytokines in plasma and bronchoalveolar fluid of endotoxemic rats

Kim A. Boost, Christian Hofstetter, Michael Flondor, Christian Betz, Markus Homann, Josef Pfeilschifter, Heiko Muehl, Bernhard Zwissler
Pages: 1139-1144
Published online on: 01 June 2006

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Article

Comparative integromics on Angiopoietin family members

Yuriko Katoh, Masaru Katoh
Pages: 1145-1149
Published online on: 01 June 2006

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Article

Evidence of circulating donor genetic material in bone allotransplantation

T. Partsalis, L. Y.S. Chan, M. Hurworth, C. Willers, N. Pavlos, N. Kumta, D. Wood, J. Xu, S. Kumta, Y. M.D. Lo, M. H. Zheng
Pages: 1151-1155
Published online on: 01 June 2006

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Article

Cytoprotective effects of Lycium barbarum against reducing stress on endoplasmic reticulum

Man-Shan Yu, Yuen-Shan Ho, Kwok-Fai So, Wai-Hung Yuen, Raymond Chuen-Chung Chang
Pages: 1157-1161
Published online on: 01 June 2006

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Article

Canonical WNT signaling pathway and human AREG

Yuriko Katoh, Masaru Katoh
Pages: 1163-1166
Published online on: 01 June 2006

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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