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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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February 2012 Volume 29 Issue 2

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Article

The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. IV. D-glucose metabolism by isolated pancreatic islets

  • Authors:
    • Zoheir Mellouk
    • Ying Zhang
    • Nurdan Bulur
    • Karim Louchami
    • Abdullah Sener
    • Dalila Ait Yahia
    • Willy J. Malaisse
  • View Affiliations / Copyright

    Affiliations: Department of Biology, Es-Sénia University, Oran, Algeria, Laboratory of Experimental Hormonology, Université Libre de Bruxelles, 808 Route de Lennik, B-1070 Brussels, Belgium
  • Pages: 291-293
    |
    Published online on: November 7, 2011
       https://doi.org/10.3892/ijmm.2011.824
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Abstract

The major aim of the present study was to search for changes of D-glucose metabolism in isolated pancreatic islets possibly involved in the alteration of their secretory response to the hexose, as observed when comparing rats exposed for 8 weeks to diets containing either starch and sunflower oil or fructose and sunflower oil, as well as rats exposed to diets containing fructose, sunflower oil and either salmon oil or safflower oil. The substitution of starch by fructose in the diet affected unfavourably D-glucose phosphorylation by the isolated islets. In the fructose-fed rats, there was a close parallelism between D-[5-3H]glucose utilization and the dietary ω3/ω6 fatty acid ratio. There was little to distinguish, however, between the four groups of rats in terms of D-[U-14C]glucose oxidation. The paired ratio between D-[U-14C]glucose oxidation and D-[5-3H]glucose utilization, which always increased as the concentration of the hexose was raised from 2.8 to 8.3 and 16.7 mM, was tightly related, in the fructose-fed rats, to the HOMA index for insulin resistance.

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Copy and paste a formatted citation
Spandidos Publications style
Mellouk Z, Zhang Y, Bulur N, Louchami K, Sener A, Ait Yahia D and Malaisse W : The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. IV. D-glucose metabolism by isolated pancreatic islets. Int J Mol Med 29: 291-293, 2012.
APA
Mellouk, Z., Zhang, Y., Bulur, N., Louchami, K., Sener, A., Ait Yahia, D., & Malaisse, W. . (2012). The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. IV. D-glucose metabolism by isolated pancreatic islets. International Journal of Molecular Medicine, 29, 291-293. https://doi.org/10.3892/ijmm.2011.824
MLA
Mellouk, Z., Zhang, Y., Bulur, N., Louchami, K., Sener, A., Ait Yahia, D., Malaisse, W. ."The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. IV. D-glucose metabolism by isolated pancreatic islets". International Journal of Molecular Medicine 29.2 (2012): 291-293.
Chicago
Mellouk, Z., Zhang, Y., Bulur, N., Louchami, K., Sener, A., Ait Yahia, D., Malaisse, W. ."The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. IV. D-glucose metabolism by isolated pancreatic islets". International Journal of Molecular Medicine 29, no. 2 (2012): 291-293. https://doi.org/10.3892/ijmm.2011.824
Copy and paste a formatted citation
x
Spandidos Publications style
Mellouk Z, Zhang Y, Bulur N, Louchami K, Sener A, Ait Yahia D and Malaisse W : The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. IV. D-glucose metabolism by isolated pancreatic islets. Int J Mol Med 29: 291-293, 2012.
APA
Mellouk, Z., Zhang, Y., Bulur, N., Louchami, K., Sener, A., Ait Yahia, D., & Malaisse, W. . (2012). The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. IV. D-glucose metabolism by isolated pancreatic islets. International Journal of Molecular Medicine, 29, 291-293. https://doi.org/10.3892/ijmm.2011.824
MLA
Mellouk, Z., Zhang, Y., Bulur, N., Louchami, K., Sener, A., Ait Yahia, D., Malaisse, W. ."The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. IV. D-glucose metabolism by isolated pancreatic islets". International Journal of Molecular Medicine 29.2 (2012): 291-293.
Chicago
Mellouk, Z., Zhang, Y., Bulur, N., Louchami, K., Sener, A., Ait Yahia, D., Malaisse, W. ."The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. IV. D-glucose metabolism by isolated pancreatic islets". International Journal of Molecular Medicine 29, no. 2 (2012): 291-293. https://doi.org/10.3892/ijmm.2011.824
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