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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2012 Volume 29 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Heme breakdown and ischemia/reperfusion injury in grafted liver during living donor liver transplantation

Junya Matsumi, Hiroshi Morimatsu, Takashi Matsusaki, Ryuji Kaku, Hiroko Shimizu, Toru Takahashi, Takahito Yagi, Masaki Matsumi, Kiyoshi Morita
Pages: 135-140
Published online on: 27 October 2011

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RNA-binding activity of the rat calmodulin-binding PEP-19 protein and of the long PEP-19 isoform

Patrizia Saladino, Carlo Maria Di Liegro, Patrizia Proia, Anna Sala, Gabriella Schiera, Alessandra Lo Cicero, Italia Di Liegro
Pages: 141-145
Published online on: 20 October 2011

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Article Open Access

Xenogeneic chondrocytes promote stable subcutaneous chondrogenesis of bone marrow-derived stromal cells

Ke Xue, Yueqian Zhu, Yingying Zhang, Chengan Chiang, Guangdong Zhou, Kai Liu
Pages: 146-152
Published online on: 07 November 2011

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Article

Structural property of soybean protein P34 and specific IgE response to recombinant P34 in patients with soybean allergy

Hideyuki Morita, Hideo Kaneko, Hidenori Ohnishi, Zenichiro Kato, Kazuo Kubota, Takahiro Yamamoto, Eiko Matsui, Takahide Teramoto, Toshiyuki Fukao, Kimiko Kasahara, Naomi Kondo
Pages: 153-158
Published online on: 16 November 2011

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Article

Emodin inhibits the differentiation and maturation of dendritic cells and increases the production of regulatory T cells

Wei Zhang, Hong Li, Heqi Bu, Hui Chen, Hongfei Tong, Dianlei Liu, Hongchun Guo, Sheng-Zhang Lin
Pages: 159-164
Published online on: 20 October 2011

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Article

Hsp40 regulates the amount of keratin proteins via ubiquitin-proteasome pathway in cultured human cells

Shota Yamazaki, Asato Uchiumi, Yohtaro Katagata
Pages: 165-168
Published online on: 07 November 2011

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Article

The inhibitory effect and the molecular mechanism of glabridin on RANKL-induced osteoclastogenesis in RAW264.7 cells

Hyun-Sook Kim, Kwang Sik Suh, Donggeun Sul, Byung-Jo Kim, Seung Kwan Lee, Woon-Won Jung
Pages: 169-177
Published online on: 31 October 2011

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Article

In vivo degradation behavior and biocompatibility of Mg-Nd-Zn-Zr alloy at early stage

Yongping Wang, Zhaojin Zhu, Yaohua He, Yao Jiang, Jian Zhang, Jialin Niu, Lin Mao, Guangyin Yuan
Pages: 178-184
Published online on: 20 October 2011

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Article

Delayed healing and induction of secretory leukocyte protease inhibitor in polycystic ovary syndrome rat skin wounds

Soon-Jeong Jeong, Sung-Shin Kim, Chun-Sik Bae, Jin-Ju Park, Baik-Dong Choi, Guanlin Wang, Myung-Ju Jung, Hyun-Sun Jang, Byung-Ock Kim, Do-Seon Lim, Young-Sik Cho, Moon-Jin Jeong
Pages: 185-194
Published online on: 20 October 2011

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Article

Adenosine stimulates growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles

Kyung-A Hwang, Yul-Lye Hwang, Min-Ho Lee, Na-Ri Kim, Seok-Seon Roh, Young Lee, Chang Deok Kim, Jeung-Hoon Lee, Kyung-Chul Choi
Pages: 195-201
Published online on: 20 October 2011

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Article

VSL#3 probiotics regulate the intestinal epithelial barrier in vivo and in vitro via the p38 and ERK signaling pathways

Cong Dai, De-Hui Zhao, Min Jiang
Pages: 202-208
Published online on: 15 November 2011

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Article

Mangosteen leaf extract increases melanogenesis in B16F1 melanoma cells by stimulating tyrosinase activity in vitro and by up-regulating tyrosinase gene expression

Mariani Abdul Hamid, Mohamad Roji Sarmidi, Chang Seo Park
Pages: 209-217
Published online on: 15 November 2011

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Article

Combination therapy of conditionally replicating adenovirus and histone deacetylase inhibitors

Dal Rae Kim, Mi-Young Park, Hyo-Jeong Lim, Jong Sun Park, Young Jae Cho, Sei-Won Lee, Ho-Il Yoon, Jae-Ho Lee, Yeon-Soo Kim, Choon-Taek Lee
Pages: 218-224
Published online on: 07 November 2011

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Article

Maspin increases Ku70 acetylation and Bax-mediated cell death in cancer cells

Sook-Ja Lee, Haerim Jang, Chaehwa Park
Pages: 225-230
Published online on: 10 November 2011

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Article

Reduced expression of FXYD domain containing ion transport regulator 5 in association with hypertension

Xiaoyan Huang, Benji Wang, Deye Yang, Xiangxiang Shi, Jian Hong, Suyun Wang, Xiaochun Dai, Xi Zhou, Yong-Jian Geng
Pages: 231-238
Published online on: 11 November 2011

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Article

The induction of rat spermatogonial stem cells into neuronal-like cells and behavioral recovery following transplantation in a rat Parkinson's disease model

Te Liu, Zhangbin Gong, Lengchen Hou, Yongyi Huang
Pages: 239-244
Published online on: 07 November 2011

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Article

Inhibitory effect of Trolox on the migration and invasion of human lung and cervical cancer cells

Ho Joong Sung, Yoonseo Kim, Hyereen Kang, Jae Woong Sull, Yoon Suk Kim, Sung-Wuk Jang, Jesang Ko
Pages: 245-251
Published online on: 07 November 2011

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Article

Evaluation of the anticancer activities of thioflavanone and thioflavone in human breast cancer cell lines

Eun Jeong Choi, Jae In Lee, Gun-Hee Kim
Pages: 252-256
Published online on: 10 November 2011

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Article

Parthenogenetic embryonic stem cells with H19 siRNA-mediated knockdown as a potential resource for cell therapy

Minhye Kwak, Su Hong, Seong-Lan Yu, Bo-Woong Sim, Jeong-Sun Seo, Jaeku Kang
Pages: 257-262
Published online on: 15 November 2011

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Article

Purification and characterization of a novel alkaline serine protease secreted by Vibrio metschnikovii

Jae Yeong Park, Jung Eun Park, Jong Woo Park, Seong Myeong Yoon, Jung Sup Lee
Pages: 263-268
Published online on: 13 October 2011

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Article

Losartan inhibits conventional dendritic cell maturation and Th1 and Th17 polarization responses: Νovel mechanisms of preventive effects on lipopolysaccharide-induced acute lung injury

Jun Liu, Peng-Shu Zhang, Qing Yu, Ling Liu, Yi Yang, Feng-Mei Guo, Hai-Bo Qiu
Pages: 269-276
Published online on: 20 October 2011

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Selective cell cycle arrest and induction of apoptosis in human prostate cancer cells by a polyphenol-rich extract of Solanum nigrum

Akbar Nawab, Vijay S. Thakur, Mohammad Yunus, Abbas Ali Mahdi, Sanjay Gupta
Pages: 277-284
Published online on: 10 November 2011

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The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. III. Secretory behaviour of isolated pancreatic islets

Zoheir Mellouk, Ying Zhang, Nurdan Bulur, Karim Louchami, Willy J. Malaisse, Dalila Ait Yahia, Abdullah Sener
Pages: 285-290
Published online on: 12 October 2011

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The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. IV. D-glucose metabolism by isolated pancreatic islets

Zoheir Mellouk, Ying Zhang, Nurdan Bulur, Karim Louchami, Abdullah Sener, Dalila Ait Yahia, Willy J. Malaisse
Pages: 291-293
Published online on: 07 November 2011

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Article

Synergistic effects of octylphenol and isobutyl paraben on the expression of calbindin-D9k in GH3 rat pituitary cells

Yeong Ri Kim, Eui-Man Jung, Kyung-Chul Choi, Eui-Bae Jeung
Pages: 294-302
Published online on: 07 November 2011

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Article

Ripe fruit of Rubus coreanus inhibits mast cell-mediated allergic inflammation

Hui-Hun Kim, Phil Hyung Choi, Jin-Su Yoo, Hoon Jeon, Byeong-Suk Chae, Jeong-Suk Park, Sang-Hyun Kim, Tae-Yong Shin
Pages: 303-310
Published online on: 07 November 2011

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Article

Dietary sardine protein lowers insulin resistance, leptin and TNF-α and beneficially affects adipose tissue oxidative stress in rats with fructose-induced metabolic syndrome

Zohra Madani, Karim Louchami, Abdullah Sener, Willy J. Malaisse, Dalila Ait Yahia
Pages: 311-318
Published online on: 11 November 2011

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Article

Correlation of PU.1 and signal regulatory protein α1 expression in PU.1 transgenic K562 cells

Yuko Iseki, Masako Nakahara, Makoto Kubo, Fumiya Obata, Hideo Harigae, Shinichiro Takahashi
Pages: 319-323
Published online on: 07 November 2011

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Article

Clobetasol down-regulates SLPI expression in U937 monocytoid cells

Naoko Okumura, Hitomi Yoshida, Yasuko Kitagishi, Yuri Nishimura, Satoru Matsuda
Pages: 324-326
Published online on: 07 November 2011

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

DUSP26: Unveiling a critical molecular mediator and therapeutic target in developmental dysplasia of the hip‑associated secondary osteoarthritis

Enbo Wang, Haixiang Zhang, Dechao Wu, Sadik Ali, Xianglu Ji
Article Number: 105
Published online on: 26 February 2026

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mTOR signaling pathway in primary Sjögren's syndrome: Pathogenesis and potential therapeutic targets (Review)

Rongxiu Huo, Yanting Yang, Chengcheng Wei, Yang Yang, Danli Meng, Jinying Lin, Xinxiang Huang
Article Number: 104
Published online on: 25 February 2026

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Bumetanide‑blocked SLC12A2 exerts a protective effect in experimental diabetic retinopathy

Yuting Zhang, Xiuli Wang, Qinyue Xie, Yue Huang, Dongjia Huang, Ziqing Liu, Tong Xu, Man Ni, Hongwei Yang
Article Number: 103
Published online on: 25 February 2026

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Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 102
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] A novel role for Livin in the response to ultraviolet B radiation and pterygium development

Shuang-Qing Wu, Qi-Bin Xu, Wen-Yan Sheng, Lin-Ya Su, Li-Wei Zhu
Article Number: 101
Published online on: 24 February 2026

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Endothelial UNC5B regulates blood‑retinal barrier homeostasis

Yujia Yao, Suyu Wang, Jiajun Li, Qianzi Jin, Ziyi Chen, Qin Jiang, Keran Li
Article Number: 100
Published online on: 20 February 2026

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Metabolic hubs in reproduction: The regulatory network of lipid droplets in gamete and embryo physiology (Review)

Liuzhu Pan, Zongzhuang Wen, Yi Jin
Article Number: 99
Published online on: 17 February 2026

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The role and mechanism of IL‑35 in myasthenia gravis (Review)

Jing Mao, Lin-Ming Zhang, Yan-Lin Zhu, Shu-Ji Gao, Ming-Wei Liu
Article Number: 98
Published online on: 17 February 2026

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miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways

Jing Wang, Yujia Zou, Yani Wang, Zheming Yang, Daoshen Liu, Xiaolin Su, Haixu Song, Kai Xu, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 97
Published online on: 16 February 2026

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Dysregulated post‑translational modifications in granulosa cells drive ovarian dysfunction and potential infertility applications (Review)

Yufei Zhong, Yunfei Zou, Zhuoyuan Yang, Junjun Wang, Zezheng Pan, Jiugeng Feng
Article Number: 96
Published online on: 16 February 2026

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Microglia‑mediated neuroinflammation in intracerebral hemorrhage: Pathological mechanisms and implications for therapeutic development (Review)

Xuehui Fan, Changzhi Pu, Luyi Zhong, Oucheng Wang, Binyi Zhao, Dongyi Liao, Xue Bai, Guiquan Chen, Guoqiang Yang
Article Number: 95
Published online on: 16 February 2026

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Correction Open Access

[Corrigendum] Silencing of Rac1 modifies lung cancer cell migration, invasion and actin cytoskeleton rearrangements and enhances chemosensitivity to antitumor drugs

Qing-Yong Chen, Li-Qun Xu, De-Min Jiao, Qing-Hua Yao, Yan-Yi Wang, Hui-Zhen Hu, Yu-Quan Wu, Jia Song, Jie Yan, Li-Jun Wu
Article Number: 94
Published online on: 12 February 2026

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Orcinol glucoside ameliorates pulmonary fibrosis by suppressing hyaluronic acid synthesis and macrophage M2 polarization via targeting hyaluronic acid synthase 2

Caizi Li, Xinglinzi Tang, Xiaoru Luo, Xin Lai, Jing Yang, Zheng Xu, Gulizeba Muhetaer, Yizi Xie, Xiufang Huang, Hang Li
Article Number: 93
Published online on: 10 February 2026

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Helicobacter pylori and hyperglycemia fuel gastric cancer glycolysis: Mechanisms and targeted intervention (Review)

Youjia Liu, Fang Wang, Ya Deng, Yanxia Hu, Feihong Shu, Jie Yu, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Qian Du, Jingyu Xu, Rui Xie
Article Number: 92
Published online on: 09 February 2026

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Targeting the gut‑bone axis through exercise: A novel approach to osteoporosis prevention and treatment (Review)

Jingjing Wu, Siqi Zhang, Junjie Wu, Yuhang Luan, Xingchen Yao, Boyan Xu, Yiting Wang, Yingyue Sheng, Yuzheng Xue, Yilin Ren
Article Number: 91
Published online on: 09 February 2026

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Chorus line in oral squamous cell carcinoma: How stromal and immune players orchestrate tumor progression (Review)

Eliano Cascardi, Mario Della Mura, Nicoletta Sgarro, Silvia Minei, Gerardo Cazzato, Eugenio Maiorano, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Fábio França Vieira E Silva, Eleonora Lo Muzio, Mario Dioguardi, Andrea Ballini
Article Number: 90
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] Hsa_circularRNA_0079201 suppresses chondrocyte proliferation and endochondral ossification by regulating the microRNA‑140‑3p/SMAD2 signaling pathway in idiopathic short stature 

Xijuan Liu, Chen Yan, Xueqiang Deng, Jingyu Jia
Article Number: 89
Published online on: 09 February 2026

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Post‑translational modifications in diabetic kidney disease (Review)

Mengfei He, Zihang Wang, Zhuang Miao, Yu Zhao, Lingling Wei, Lijie Zhang, Ruili Yin, Yan Wang, Longyan Yang
Article Number: 88
Published online on: 09 February 2026

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Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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May-2026 Volume 57 Issue 5

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Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

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Article Number: 108
Published online on: 02 March 2026

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Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)

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Article Number: 107
Published online on: 02 March 2026

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Correction Open Access

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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