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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2012 Volume 29 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Heme breakdown and ischemia/reperfusion injury in grafted liver during living donor liver transplantation

Junya Matsumi, Hiroshi Morimatsu, Takashi Matsusaki, Ryuji Kaku, Hiroko Shimizu, Toru Takahashi, Takahito Yagi, Masaki Matsumi, Kiyoshi Morita
Pages: 135-140
Published online on: 27 October 2011

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RNA-binding activity of the rat calmodulin-binding PEP-19 protein and of the long PEP-19 isoform

Patrizia Saladino, Carlo Maria Di Liegro, Patrizia Proia, Anna Sala, Gabriella Schiera, Alessandra Lo Cicero, Italia Di Liegro
Pages: 141-145
Published online on: 20 October 2011

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Xenogeneic chondrocytes promote stable subcutaneous chondrogenesis of bone marrow-derived stromal cells

Ke Xue, Yueqian Zhu, Yingying Zhang, Chengan Chiang, Guangdong Zhou, Kai Liu
Pages: 146-152
Published online on: 07 November 2011

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Article

Structural property of soybean protein P34 and specific IgE response to recombinant P34 in patients with soybean allergy

Hideyuki Morita, Hideo Kaneko, Hidenori Ohnishi, Zenichiro Kato, Kazuo Kubota, Takahiro Yamamoto, Eiko Matsui, Takahide Teramoto, Toshiyuki Fukao, Kimiko Kasahara, Naomi Kondo
Pages: 153-158
Published online on: 16 November 2011

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Emodin inhibits the differentiation and maturation of dendritic cells and increases the production of regulatory T cells

Wei Zhang, Hong Li, Heqi Bu, Hui Chen, Hongfei Tong, Dianlei Liu, Hongchun Guo, Sheng-Zhang Lin
Pages: 159-164
Published online on: 20 October 2011

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Hsp40 regulates the amount of keratin proteins via ubiquitin-proteasome pathway in cultured human cells

Shota Yamazaki, Asato Uchiumi, Yohtaro Katagata
Pages: 165-168
Published online on: 07 November 2011

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The inhibitory effect and the molecular mechanism of glabridin on RANKL-induced osteoclastogenesis in RAW264.7 cells

Hyun-Sook Kim, Kwang Sik Suh, Donggeun Sul, Byung-Jo Kim, Seung Kwan Lee, Woon-Won Jung
Pages: 169-177
Published online on: 31 October 2011

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In vivo degradation behavior and biocompatibility of Mg-Nd-Zn-Zr alloy at early stage

Yongping Wang, Zhaojin Zhu, Yaohua He, Yao Jiang, Jian Zhang, Jialin Niu, Lin Mao, Guangyin Yuan
Pages: 178-184
Published online on: 20 October 2011

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Delayed healing and induction of secretory leukocyte protease inhibitor in polycystic ovary syndrome rat skin wounds

Soon-Jeong Jeong, Sung-Shin Kim, Chun-Sik Bae, Jin-Ju Park, Baik-Dong Choi, Guanlin Wang, Myung-Ju Jung, Hyun-Sun Jang, Byung-Ock Kim, Do-Seon Lim, Young-Sik Cho, Moon-Jin Jeong
Pages: 185-194
Published online on: 20 October 2011

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Adenosine stimulates growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles

Kyung-A Hwang, Yul-Lye Hwang, Min-Ho Lee, Na-Ri Kim, Seok-Seon Roh, Young Lee, Chang Deok Kim, Jeung-Hoon Lee, Kyung-Chul Choi
Pages: 195-201
Published online on: 20 October 2011

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VSL#3 probiotics regulate the intestinal epithelial barrier in vivo and in vitro via the p38 and ERK signaling pathways

Cong Dai, De-Hui Zhao, Min Jiang
Pages: 202-208
Published online on: 15 November 2011

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Mangosteen leaf extract increases melanogenesis in B16F1 melanoma cells by stimulating tyrosinase activity in vitro and by up-regulating tyrosinase gene expression

Mariani Abdul Hamid, Mohamad Roji Sarmidi, Chang Seo Park
Pages: 209-217
Published online on: 15 November 2011

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Combination therapy of conditionally replicating adenovirus and histone deacetylase inhibitors

Dal Rae Kim, Mi-Young Park, Hyo-Jeong Lim, Jong Sun Park, Young Jae Cho, Sei-Won Lee, Ho-Il Yoon, Jae-Ho Lee, Yeon-Soo Kim, Choon-Taek Lee
Pages: 218-224
Published online on: 07 November 2011

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Maspin increases Ku70 acetylation and Bax-mediated cell death in cancer cells

Sook-Ja Lee, Haerim Jang, Chaehwa Park
Pages: 225-230
Published online on: 10 November 2011

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Article

Reduced expression of FXYD domain containing ion transport regulator 5 in association with hypertension

Xiaoyan Huang, Benji Wang, Deye Yang, Xiangxiang Shi, Jian Hong, Suyun Wang, Xiaochun Dai, Xi Zhou, Yong-Jian Geng
Pages: 231-238
Published online on: 11 November 2011

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The induction of rat spermatogonial stem cells into neuronal-like cells and behavioral recovery following transplantation in a rat Parkinson's disease model

Te Liu, Zhangbin Gong, Lengchen Hou, Yongyi Huang
Pages: 239-244
Published online on: 07 November 2011

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Inhibitory effect of Trolox on the migration and invasion of human lung and cervical cancer cells

Ho Joong Sung, Yoonseo Kim, Hyereen Kang, Jae Woong Sull, Yoon Suk Kim, Sung-Wuk Jang, Jesang Ko
Pages: 245-251
Published online on: 07 November 2011

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Evaluation of the anticancer activities of thioflavanone and thioflavone in human breast cancer cell lines

Eun Jeong Choi, Jae In Lee, Gun-Hee Kim
Pages: 252-256
Published online on: 10 November 2011

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Parthenogenetic embryonic stem cells with H19 siRNA-mediated knockdown as a potential resource for cell therapy

Minhye Kwak, Su Hong, Seong-Lan Yu, Bo-Woong Sim, Jeong-Sun Seo, Jaeku Kang
Pages: 257-262
Published online on: 15 November 2011

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Purification and characterization of a novel alkaline serine protease secreted by Vibrio metschnikovii

Jae Yeong Park, Jung Eun Park, Jong Woo Park, Seong Myeong Yoon, Jung Sup Lee
Pages: 263-268
Published online on: 13 October 2011

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Losartan inhibits conventional dendritic cell maturation and Th1 and Th17 polarization responses: Νovel mechanisms of preventive effects on lipopolysaccharide-induced acute lung injury

Jun Liu, Peng-Shu Zhang, Qing Yu, Ling Liu, Yi Yang, Feng-Mei Guo, Hai-Bo Qiu
Pages: 269-276
Published online on: 20 October 2011

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Selective cell cycle arrest and induction of apoptosis in human prostate cancer cells by a polyphenol-rich extract of Solanum nigrum

Akbar Nawab, Vijay S. Thakur, Mohammad Yunus, Abbas Ali Mahdi, Sanjay Gupta
Pages: 277-284
Published online on: 10 November 2011

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The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. III. Secretory behaviour of isolated pancreatic islets

Zoheir Mellouk, Ying Zhang, Nurdan Bulur, Karim Louchami, Willy J. Malaisse, Dalila Ait Yahia, Abdullah Sener
Pages: 285-290
Published online on: 12 October 2011

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The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. IV. D-glucose metabolism by isolated pancreatic islets

Zoheir Mellouk, Ying Zhang, Nurdan Bulur, Karim Louchami, Abdullah Sener, Dalila Ait Yahia, Willy J. Malaisse
Pages: 291-293
Published online on: 07 November 2011

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Synergistic effects of octylphenol and isobutyl paraben on the expression of calbindin-D9k in GH3 rat pituitary cells

Yeong Ri Kim, Eui-Man Jung, Kyung-Chul Choi, Eui-Bae Jeung
Pages: 294-302
Published online on: 07 November 2011

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Article

Ripe fruit of Rubus coreanus inhibits mast cell-mediated allergic inflammation

Hui-Hun Kim, Phil Hyung Choi, Jin-Su Yoo, Hoon Jeon, Byeong-Suk Chae, Jeong-Suk Park, Sang-Hyun Kim, Tae-Yong Shin
Pages: 303-310
Published online on: 07 November 2011

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Dietary sardine protein lowers insulin resistance, leptin and TNF-α and beneficially affects adipose tissue oxidative stress in rats with fructose-induced metabolic syndrome

Zohra Madani, Karim Louchami, Abdullah Sener, Willy J. Malaisse, Dalila Ait Yahia
Pages: 311-318
Published online on: 11 November 2011

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Article

Correlation of PU.1 and signal regulatory protein α1 expression in PU.1 transgenic K562 cells

Yuko Iseki, Masako Nakahara, Makoto Kubo, Fumiya Obata, Hideo Harigae, Shinichiro Takahashi
Pages: 319-323
Published online on: 07 November 2011

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Clobetasol down-regulates SLPI expression in U937 monocytoid cells

Naoko Okumura, Hitomi Yoshida, Yasuko Kitagishi, Yuri Nishimura, Satoru Matsuda
Pages: 324-326
Published online on: 07 November 2011

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

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miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam Martínez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

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Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

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Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

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Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

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Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

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A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

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Retraction Open Access

[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

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Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

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Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

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Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

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Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

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FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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