Reduction of protein kinase MARK4 in the brains of experimental scrapie rodents and human prion disease correlates with deposits of PrPSc

SB PrusinerPrionsProc Natl Acad Sci USA951336313383199810.1073/pnas.95.23.133639811807

B CaugheyB ChesebroPrion protein and the transmissible spongiform encephalopathiesTrends Cell Biol75662199710.1016/S0962-8924(96)10054-417708907

J CastillaP SaaC HetzC SotoIn vitro generation of infectious scrapie prionsCell121195206200510.1016/j.cell.2005.02.01115851027

G LegnameIV BaskakovHO NguyenSynthetic mammalian prionsScience305673676200410.1126/science.1100195

MP McKinleyDC BoltonSB PrusinerA protease-resistant protein is a structural component of the scrapie prionCell355762198310.1016/0092-8674(83)90207-66414721

A DesaiTJ MitchisonMicrotubule polymerization dynamicsAnnu Rev Cell Dev Biol1383117199710.1146/annurev.cellbio.13.1.83

GG GundersenEvolutionary conservation of microtubule-capture mechanismsNat Rev Mol Cell Biol3296304200210.1038/nrm77711994749

GR WangS ShiC GaoChanges of tau profiles in brains of the hamsters infected with scrapie strains 263 K or 139 A possibly associated with the alteration of phosphate kinasesBMC Infect Dis1086201010.1186/1471-2334-10-8620356412

CF DongS ShiXF WangThe N-terminus of PrP is responsible for interacting with tubulin and fCJD related PrP mutants possess stronger inhibitive effect on microtubule assembly in vitroArch Biochem Biophys4708392200810.1016/j.abb.2007.11.00718037369

XL LiGR WangYY JingCytosolic PrP induces apoptosis of cell by disrupting microtubule assemblyJ Mol Neurosci43316325201110.1007/s12031-010-9443-920838930

B TrinczekM BrajenovicA EbnethG DrewesMARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomesJ Biol Chem27959155923200410.1074/jbc.M304528200

T KatoS SatohH OkabeIsolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesisNeoplasia349200110.1038/sj.neo.790013211326310

A SchneiderR LaageO von AhsenIdentification of regulated genes during permanent focal cerebral ischaemia: characterization of the protein kinase 9b5/MARKL1/MARK4J Neurochem8811141126200410.1046/j.1471-4159.2003.02228.x

A BeghiniI MagnaniG RoversiThe neural progenitor-restricted isoform of the MARK4 gene in 19q13.2 is upregulated in human gliomas and overexpressed in a subset of glioblastoma cell linesOncogene2225812591200310.1038/sj.onc.120633612735302

M HasegawaM Morishima-KawashimaK TakioM SuzukiK TitaniY IharaProtein sequence and mass spectrometric analyses of tau in the Alzheimer’s disease brainJ Biol Chem26717047170541992

EM MandelkowE ThiesB TrinczekJ BiernatE MandelkowMARK/PAR1 kinase is a regulator of microtubule-dependent transport in axonsJ Cell Biol16799110200410.1083/jcb.20040108515466480

J ZhangL ChenBY ZhangComparison study on clinical and neuropathological characteristics of hamsters inoculated with scrapie strain 263K in different challenging pathwaysBiomed Environ Sci1765782004

YS KimRI CarpSM CallahanHM WisniewskiIncubation periods and survival times for mice injected stereotaxically with three scrapie strains in different brain regionsJ Gen Virol68695702198710.1099/0022-1317-68-3-6953546594

J YeJ HanQ ShiHuman prion disease with a G114V mutation and epidemiological studies in a Chinese family: a case seriesJ Med Case Rep2331200810.1186/1752-1947-2-33118925969

Q ShiBY ZhangC GaoJ HanGR WangC ChenC TianXP DongThe pathological and pathogenic characteristics in various brain regions from a Chinese patient with G114V genetic CJDNeuropathology325159201210.1111/j.1440-1789.2011.01237.x21732990

XH ShiJ HanJ ZhangClinical, histopathological and genetic studies in a family with fatal familial insomniaInfect Genet Evol10292297201010.1016/j.meegid.2010.01.00720096809

JM ChenC GaoQ ShiDifferent expression patterns of CK2 subunits in the brains of experimental animals and patients with transmissible spongiform encephalopathiesArch Virol15310131020200810.1007/s00705-008-0084-z

G ForloniN AngerettiR ChiesaNeurotoxicity of a prion protein fragmentNature362543546199310.1038/362543a08464494

T FlorioS ThellungC AmicoPrion protein fragment 106–126 induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell lineJ Neurosci Res543413521998

M EttaicheR PichotJP VincentJ ChabryIn vivo cytotoxicity of the prion protein fragment 106–126J Biol Chem27536487364902000

G DrewesB TrinczekS IllenbergerMicrotubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262J Biol Chem270767976881995

G ManningDB WhyteR MartinezT HunterS SudarsanamThe protein kinase complement of the human genomeScience29819121934200210.1126/science.107576212471243

RF MoroniS De BiasiP ColapietroL LarizzaA BeghiniDistinct expression pattern of microtubule-associated protein/microtubule affinity-regulating kinase 4 in differentiated neuronsNeuroscience1438394200610.1016/j.neuroscience.2006.07.052

F TagliaviniF PrelliL VergaSynthetic peptides homologous to prion protein residues 106–147 form amyloid-like fibrils in vitroProc Natl Acad Sci USA90967896821993

YH LiuYL HanJ SongHeat shock protein 104 inhibited the fibrillization of prion peptide 106–126 and disassembled prion peptide 106–126 fibrils in vitroInt J Biochem Cell Biol43768774201121296677

I MagnaniC NovielliM BelliniG RoversiL BelloL LarizzaMultiple localization of endogenous MARK4L protein in human gliomaCell Oncol31357370200919759416

RD TerryThe pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesisJ Neuropathol Exp Neurol5510231025199610.1097/00005072-199655100-000018857998

EM MandelkowJ BiernatG DrewesN GustkeB TrinczekE MandelkowTau domains, phosphorylation, and interactions with microtubulesNeurobiol Aging16355363199510.1016/0197-4580(95)00025-A7566345

M ZunguJC SchislerMF EssopC McCuddenC PattersonMS WillisRegulation of AMPK by the ubiquitin proteasome systemAm J Pathol178411201110.1016/j.ajpath.2010.11.03021224036

AK Al-HakimA ZagorskaL ChapmanM DeakM PeggieDR AlessiControl of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chainsBiochem J411249260200810.1042/BJ2008006718254724

J SatohS ObayashiT MisawaK SumiyoshiK OosumiH TabunokiProtein microarray analysis identifies human cellular prion protein interactorsNeuropathol Appl Neurobiol351635200910.1111/j.1365-2990.2008.00947.x18482256

K StamerR VogelE ThiesE MandelkowEM MandelkowTau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stressJ Cell Biol15610511063200210.1083/jcb.20010805711901170

A EbnethR GodemannK StamerS IllenbergerB TrinczekE MandelkowOverexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer’s diseaseJ Cell Biol14377779419989813097