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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2012 Volume 30 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

In vitro and in vivo properties of a fully human IgG1 monoclonal antibody that combats multidrug resistant Pseudomonas aeruginosa

Azmi Adawi, Carlo Bisignano, Tiziana Genovese, Angela Filocamo, Camellia Khouri-Assi, Anat Neville, Giora Z. Feuerstein, Salvatore Cuzzocrea, Lewis F. Neville
Pages: 455-464
Published online on: 20 June 2012

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Article Open Access

Targeting of the anti-apoptotic gene survivin in human thyroid carcinoma

Zhouxun Chen, Naxin Liu, Guanbao Zhu, Henning Dralle, Cuong Hoang-Vu
Pages: 465-472
Published online on: 28 June 2012

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Article Open Access

Silymarin suppresses hepatic stellate cell activation in a dietary rat model of non-alcoholic steatohepatitis: Αnalysis of isolated hepatic stellate cells

Mina Kim, Su-Geun Yang, Joon Mi Kim, Jin-Woo Lee, Young Soo Kim, Jung Il Lee
Pages: 473-479
Published online on: 14 June 2012

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Article Open Access

Establishment of immortalized Schwann cells derived from rat embryo dorsal root ganglia

Huajun Jiang, Wei Qu, Feng Han, Dazhuang Liu, Weiguo Zhang
Pages: 480-486
Published online on: 06 June 2012

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Article Open Access

A mechanism underlying the effects of polyunsaturated fatty acids on breast cancer

Hao Zhang, Lei Zhou, Wei Shi, Ning Song, Karu Yu, Yuchun Gu
Pages: 487-494
Published online on: 11 June 2012

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Article

The basic helix-loop-helix transcription factor DEC2 inhibits TGF-β-induced tumor progression in human pancreatic cancer BxPC-3 cells

Fuyuki Sato, Haruka Kawamura, Yunyan Wu, Hiroyasu Sato, Daiki Jin, Ujjal Kumar Bhawal, Takeshi Kawamoto, Katsumi Fujimoto, Mitsuhide Noshiro, Hiroko Seino, Satomo Morohashi, Yukio Kato, Hiroshi Kijima
Pages: 495-501
Published online on: 19 June 2012

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Article

Immunohistochemical analysis of TGF-β1 and VEGF in gingival and periodontal tissues: A role of these biomarkers in the pathogenesis of scleroderma and periodontal disease

Giovanni Matarese, Gaetano Isola, Giuseppe Pio Anastasi, Angelo Favaloro, Demetrio Milardi, Giovanna Vermiglio, Giuseppe Vita, Giancarlo Cordasco, Giuseppina Cutroneo
Pages: 502-508
Published online on: 11 June 2012

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Article

Temporal change in IL-6 mRNA and protein expression produced by cyclic stretching of human pulmonary artery endothelial cells

Kozue Kobayashi, Masumi Tanaka, Satoru Nebuya, Kenichi Kokubo, Yutaka Fukuoka, Yoshiteru Harada, Hirouske Kobayashi, Makoto Noshiro, Hidenori Inaoka
Pages: 509-513
Published online on: 11 June 2012

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Article

siRNA-based targeting of fractalkine overexpression suppresses inflammation development in a severe acute pancreatitis rat model

Liya Huang, Junwen Ma, Yuming Tang, Ping Chen, Shuxian Zhang, Yongping Zhang, Yao Zong Yuan
Pages: 514-520
Published online on: 29 June 2012

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Article

Mutation screening of TRPM1, GRM6, NYX and CACNA1F genes in patients with congenital stationary night blindness

Qin Wang, Yang Gao, Shiqiang Li, Xiangming Guo, Qingjiong Zhang
Pages: 521-526
Published online on: 20 June 2012

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Article

Therapeutic potential of bone marrow-derived mesenchymal stem cells producing pigment epithelium-derived factor in lung carcinoma

Qiaoling Chen, Ping Cheng, Tao Yin, Hong He, Li Yang, Yuquan Wei, Xiancheng Chen
Pages: 527-534
Published online on: 06 June 2012

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Article

Evaluation of the genetic variability of human papillomavirus type 52

Qiang Chen, Zhao-Yun Luo, Min Lin, Lin Yang, Li-Ye Yang, Gui-Zhi Ju
Pages: 535-544
Published online on: 06 June 2012

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Article

Interferon-γ deficiency reduces neointimal formation in a model of endoluminal endothelial injury combined with atherogenic diet

Nasim Nik Tavakoli, Angie K. Harris, David R. Sullivan, Brett D. Hambly, Shisan Bao
Pages: 545-552
Published online on: 15 June 2012

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Article

Interleukin-13 peptide kinoid vaccination attenuates allergic inflammation in a mouse model of asthma

Qiuping Jing, Tao Yin, Yang Wan, Huashan Shi, Shuntao Luo, Meng Li, Hailong Zhang, Hong He, Shijia Liu, Haoyu Li, Yuquan Wei, Li Yang
Pages: 553-560
Published online on: 19 June 2012

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Article

LPS-induced iNOS expression in N9 microglial cells is suppressed by geniposide via ERK, p38 and nuclear factor-κB signaling pathways

Gu Zhang, Jun-Lin He, Xiao-Yan Xie, Chao Yu
Pages: 561-568
Published online on: 14 June 2012

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Article

Reduction of protein kinase MARK4 in the brains of experimental scrapie rodents and human prion disease correlates with deposits of PrPSc

Han-Shi Gong, Yan Guo, Chan Tian, Wu-Ling Xie, Qi Shi, Jin Zhang, Yin Xu, Shao-Bin Wang, Bao-Yun Zhang, Cao Chen, Yong Liu, Xiao-Ping Dong
Pages: 569-578
Published online on: 12 June 2012

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Article

Damage of hair follicle stem cells and alteration of keratin expression in external radiation-induced acute alopecia

Naoki Nanashima, Koichi Ito, Takashi Ishikawa, Manabu Nakano, Toshiya Nakamura
Pages: 579-584
Published online on: 11 June 2012

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Article

A study of the anti-diabetic agents of camel milk

Ajamaluddin Malik, Abdulrahman Al-Senaidy, Ewa Skrzypczak-Jankun, Jerzy Jankun
Pages: 585-592
Published online on: 29 June 2012

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Article

Enhancing apoptotic cell clearance mitigates bacterial translocation and promotes tissue repair after gut ischemia-reperfusion injury

Rongqian Wu, Weifeng Dong, Zhimin Wang, Asha Jacob, Tianpen Cui, Ping Wang
Pages: 593-598
Published online on: 26 June 2012

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Article

Local delivery of recombinant adenovirus expressing hepatitis B virus X protein and interleukin-12 results in antitumor effects via inhibition of hepatoma cell growth and intervention of tumor microenvironment

Hong He, Ping Fan, Tao Yin, Qiaoling Chen, Huashan Shi, Sijia Liu, Haoyu Li, Qiuping  Jing, Yingying Yan, Hailong Zhang, Li Yang, Yanjun Wen, Yuhua Li, Ping Cheng
Pages: 599-605
Published online on: 12 June 2012

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Article

Grape skin and loquat leaf extracts and acai puree have potent anti-atherosclerotic and anti-diabetic activity in vitro and in vivo in hypercholesterolemic zebrafish

Jae-Yong Kim, Joo-Heon Hong, Hee Kyoung Jung, Yoo Seok Jeong, Kyung-Hyun Cho
Pages: 606-614
Published online on: 28 June 2012

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Characterization of IK cytokine expression in mouse endometrium during early pregnancy and its significance on implantation

Ruyue Shao, Xueqing Liu, Yubin Ding, Xuemei Chen, Rufei Gao, Junlin He, Yingxiong Wang
Pages: 615-621
Published online on: 11 June 2012

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Article

Effect of visfatin on the function of endothelial progenitor cells in high-fat-fed obese rats and investigation of its mechanism of action

Yang Sun, Shuchun Chen, Guangyao Song, Luping Ren, Limin Wei, Na Liu, Donemei Zhang, Xiuqin Lv
Pages: 622-628
Published online on: 14 June 2012

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Article

Hexavalent chromium targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent caspase-3 activation in L-02 hepatocytes

Fang Xiao, Yanhong Li, Lu Dai, Yuanyuan Deng, Yue Zou, Peng Li, Yuan Yang, Caigao Zhong
Pages: 629-635
Published online on: 14 June 2012

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Article

Wnt3a inhibits proliferation but promotes melanogenesis of melan-a cells

Haiying Guo, Ke Yang, Fang Deng, Yizhan Xing, Yuhong Li, Xiaohua Lian, Tian Yang
Pages: 636-642
Published online on: 14 June 2012

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Article

Curcumin ameliorates mitochondrial dysfunction associated with inhibition of gluconeogenesis in free fatty acid-mediated hepatic lipoapoptosis

Jong-Jen Kuo, Hen-Hong Chang, Tung-Hu Tsai, Tzung-Yan Lee
Pages: 643-649
Published online on: 11 June 2012

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Article

Effect of the IGF-1/PTEN/Akt/FoxO signaling pathway on the development and healing of water immersion and restraint stress-induced gastric ulcers in rats

Pan Huang, Zhengrong Zhou, Hao Wang, Quanwei Wei, Liang Zhang, Xin Zhou, Reinhold J. Hutz, Fangxiong Shi
Pages: 650-658
Published online on: 20 June 2012

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Article

Lentivirus-mediated expression of Drosophila melanogaster deoxyribonucleoside kinase driven by the hTERT promoter combined with gemcitabine: A potential strategy for cancer therapy

Nianqu Zhang, Lei Zhao, Shuai Ma, Ming Gu, Xinyu Zheng
Pages: 659-665
Published online on: 14 June 2012

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Article

TGF-β1 and IGF-1 influence the re-differentiation capacity of human chondrocytes in 3D pellet cultures in relation to different oxygen concentrations

Anika Jonitz, Katrin Lochner, Thomas Tischer, Doris Hansmann, Rainer Bader
Pages: 666-672
Published online on: 25 June 2012

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Article

Positive effect of curcumin on inflammation and mitochondrial dysfunction in obese mice with liver steatosis

Jong-Jen Kuo, Hen-Hong Chang, Tung-Hu Tsai, Tzung-Yan Lee
Pages: 673-679
Published online on: 29 June 2012

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Article

Decreased serum miR-181a is a potential new tool for breast cancer screening

Li-Juan Guo, Qing-Yun Zhang
Pages: 680-686
Published online on: 11 June 2012

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Article

Effects of chronic cocaine in rat C6 astroglial cells

Ramesh B. Badisa, Carl B. Goodman
Pages: 687-692
Published online on: 20 June 2012

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Article

Identification of ankylosing spondylitis-associated genes by expression profiling

Hui Ma, Dabo Xu, Qiang Fu
Pages: 693-696
Published online on: 28 June 2012

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Article

Role of NLRP3 and CARD8 in the regulation of TNF-α induced IL-1β release in vascular smooth muscle cells

Tebeng Nixon Tangi, Ali Ateia Elmabsout, Torbjörn Bengtsson, Allan Sirsjö, Karin Fransén
Pages: 697-702
Published online on: 12 June 2012

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Article

Effects on inflammatory responses by the sphingoid base 4,8-sphingadienine

Evelien Rozema, Markus Binder, Murty Bulusu, Valery Bochkov, Georg Krupitza, Brigitte Kopp
Pages: 703-707
Published online on: 15 June 2012

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Article

The bone anabolic carotenoid p-hydroxycinnamic acid promotes osteoblast mineralization and suppresses osteoclast differentiation by antagonizing NF-κB activation

Masayoshi Yamaguchi, M. Neale Weitzmann
Pages: 708-712
Published online on: 26 June 2012

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Article

A novel mutation of exon 7 in growth hormone receptor mRNA in a patient with growth hormone insensitivity syndrome and neurofibromatosis type I

Ju-Hyung Kang, Ok-Soon Kim, Ja-Hyun Kim, Seong-Kyu Lee, Youn-Jong Park, Haing-Woon Baik
Pages: 713-717
Published online on: 28 June 2012

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

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