Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
International Journal of Molecular Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1107-3756 Online ISSN: 1791-244X
Journal Cover
November 2012 Volume 30 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
November 2012 Volume 30 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Review

Contribution of endothelial progenitor cells to neovascularization (Review)

  • Authors:
    • Da-Wei Li
    • Zhi-Qiang Liu
    • Jun Wei
    • Ying Liu
    • Lin-Sen Hu
  • View Affiliations / Copyright

    Affiliations: Department of Neurology, The First Hospital of Jilin University, Changchun, P.R. China, Department of Neurology, Yichang Central People's Hospital, Yichang, P.R. China
  • Pages: 1000-1006
    |
    Published online on: August 23, 2012
       https://doi.org/10.3892/ijmm.2012.1108
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Endothelial progenitor cells (EPCs) are a cell population mobilized from bone marrow into the peripheral circulation and recruited into sites of vessel injury to participate in blood vessel formation in both physiological and pathological conditions. Due to the lack of unique surface markers and different isolation methods, EPCs represent heterogeneous cell populations including cells of myeloid or endothelial origin. Evidence suggests that EPCs play a critical role in postnatal blood vessel formation and vascular homeostasis and provide a promising therapy for vascular disease. However, the mechanisms by which EPCs participate in new vessel formation are still incompletely understood. We review the process of EPCs in neovascularization including EPC mobilization, migration, adhesion and effect on new vessel formation, in an attempt to better understand the underlying mechanisms and to provide potential effective management for the treatment of patients with vascular disease.
View Figures

Figure 1

Figure 2

Figure 3

View References

1. 

T AsaharaT MuroharaA Sulli vanIsolation of putative progenitor endothelial cells for angiogenesisScience275964967199710.1126/science.275.5302.9649020076

2. 

J RehmanJ LiCM OrschellKL MarchPeripheral blood ‘endothelial progenitor cells’ are derived from monocyte/macrophages and secrete angiogenic growth factorsCirculation107116411692003

3. 

MC YoderLE MeadD PraterRedefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principalsBlood10918011809200710.1182/blood-2006-08-04347117053059

4. 

J HurCH YoonHS KimCharacterization of two types of endothelial progenitor cells and their different contributions to neovasculogenesisArterioscler Thromb Vasc Biol24288293200410.1161/01.ATV.0000114236.77009.0614699017

5. 

JM HillG ZalosJPJ HalcoxCirculating endothelial progenitor cells, vascular function, and cardiovascular riskN Engl J Med348593600200310.1056/NEJMoa02228712584367

6. 

H ItoII RoviraML BloomEndothelial progenitor cells as putative targets for angiostatinCancer Res5958755877199910606226

7. 

C KalkaH MasudaT TakahashiTransplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularizationProc Natl Acad Sci USA9734223427200010.1073/pnas.97.7.342210725398

8. 

E GunsiliusHC DubaAL PetzerEvidence from a leukaemia model for maintenance of vascular endothelium by bone-marrow-derived endothelial cellsLancet35516881691200010.1016/S0140-6736(00)02241-810905245

9. 

CH YoonJ HurKW ParkSynergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinasesCirculation11216181627200510.1161/CIRCULATIONAHA.104.503433

10. 

M VasaS FichtlschererA AicherNumber and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery diseaseCirc Res89E1E7200110.1161/hh1301.09395311440984

11. 

S DimmelerA AicherM VasaHMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathwayJ Clin Invest108391397200110.1172/JCI20011315211489932

12. 

DA IngramLE MeadH TanakaV MeadeA FenoglioK MortellIdentification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord bloodBlood10427522760200410.1182/blood-2004-04-139615226175

13. 

Y LinDJ WeisdorfA SoloveyRP HebbelOrigins of circulating endothelial cells and endothelial outgrowth from bloodJ Clin Invest1057177200010.1172/JCI807110619863

14. 

DA IngramLE MeadDB MooreW WoodardA FenoglioMC YoderVessel wall-derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cellsBlood10527832786200510.1182/blood-2004-08-3057

15. 

JM Melero-MartinZA KhanA PicardIn vivo vasculogenic potential of human blood-derived endothelial progenitor cellsBlood10947614768200710.1182/blood-2006-12-06247117327403

16. 

T LapidotI PetitCurrent understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cellsExp Hematol30973981200210.1016/S0301-472X(02)00883-412225788

17. 

T LapidotA DarO KolletHow do stem cells find their way home?Blood10619011910200510.1182/blood-2005-04-141715890683

18. 

N FerraraWJ HenzelPituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cellsBiochem Biophys Res Commun161851858198910.1016/0006-291X(89)92678-8

19. 

A YoshidaB Anand-ApteBR ZetterDifferential endothelial migration and proliferation to basic fibroblast growth factor and vascular endothelial growth factorGrowth Factors135764199610.3109/089771996090345668962720

20. 

A BrkovicMG SiroisVascular permeability induced by VEGF family members in vivo: role of endogenous PAF and NO synthesisJ Cell Biochem100727737200710.1002/jcb.2112417115409

21. 

N FerraraMolecular and biological properties of vascular endothelial growth factorJ Mol Med77527543199910.1007/s00109990001910494799

22. 

J GavardJS GutkindVEGF controls endothelial cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherinNat Cell Biol812231234200610.1038/ncb148617060906

23. 

T AsaharaT TakahashiH MasudaVEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cellsEMBO J1839643972199910.1093/emboj/18.14.396410406801

24. 

C KalkaH MasudaT TakahashiVascular endothelial growth factor (165) gene transfer augments circulating endothelial progenitor cells in human subjectsCirc Res8611981202200010.1161/01.RES.86.12.1198

25. 

M GillS DiasK HattoriML RiveraD HicklinL WitteL GirardiR YurtH HimelS RafiiVascular trauma induces rapid but transient mobilization of VEGFR2(+)AC133(+) endothelial precursor cellsCirc Res88167174200111157668

26. 

F BautzS RafiiL KanzR MohleExpression and secretion of vascular endothelial growth factor-A by cytokine stimulated hematopoietic progenitor cells: possible role in the hematopoietic microenvironmentExp Hematol28700706200010.1016/S0301-472X(00)00168-5

27. 

TM PowellJD PaulJM HillGranulocyte colony-stimulating factor mobilizes functional endothelial progenitor cells in patients with coronary artery diseaseArterioscler Thromb Vasc Biol25296301200510.1161/01.ATV.0000151690.43777.e4

28. 

B HeissigK HattoriS DiasM FriedrichB FerrisNR HackettRecruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligandCell109625637200210.1016/S0092-8674(02)00754-712062105

29. 

DJ CeradiniAR KulkarniMJ CallaghanOM TepperN BastidasME KleinmanProgenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1Nat Med10858864200410.1038/nm107515235597

30. 

E De FalcoD PorcelliAR TorellaS StrainoMG IachininotoA OrlandiS TruffaP BiglioliM NapolitanoMC CapogrossiM PesceSDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cellsBlood10434723482200415284120

31. 

K HattoriB HeissigK TashiroPlasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cellsBlood9733543360200110.1182/blood.V97.11.335411369624

32. 

DH WalterJ HaendelerJ ReinholdU RochwalskyF SeegerJ HonoldJ HoffmannC UrbichR LehmannF Arenzana-SeisdesdosImpaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery diseaseCirc Res9711421151200510.1161/01.RES.0000193596.94936.2c

33. 

T AsaharaJM IsnerEndothelial progenitor cells for vascular regenerationJ Hematother Stem Cell Res11171178200210.1089/15258160275365838511983091

34. 

O KolletS ShivtielYQ ChenJ SuriawinataSN ThungMD DabevaHGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liverJ Clin Invest112160169200310.1172/JCI1790212865405

35. 

AT AskariS UnzekZB PopovicCK GoldmanF ForudiM KiedrowskiEffect of stromal-cell-derived factor 1 on stem cell homing and tissue regeneration in ischaemic cardiomyopathyLancet362697703200310.1016/S0140-6736(03)14232-812957092

36. 

H LangerAE MayK DaubU HeinzmannP LangM SchummD VestweberS MassbergT SchonbergerI PfistererAdherent platelets recruit and induce differentiation of murine embryonic endothelial progenitor cells to mature endothelial cells in vitroCirc Res98e2e10200610.1161/01.RES.0000201285.87524.9e

37. 

C UrbichA AicherC HeeschenE DernbachWK HofmannAM ZeiherS DimmelerSoluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cellsJ Mol Cell Cardiol39733742200510.1016/j.yjmcc.2005.07.00316199052

38. 

J ChenJA LopezInteractions of platelets with subendothelium and endotheliumMicrocirculation12235246200510.1080/1073968059092548415814433

39. 

ZM RuggeriMechanisms initiating platelet thrombus formationThromb Haemost7861161619979198225

40. 

S MassbergM GawazS GrunerV SchulteI KonradD ZohlnhoferA crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivoJ Exp Med1974149200310.1084/jem.2002094512515812

41. 

S MassbergK SchurzingerM LorenzI KonradC SchulzN PlesnilaE KennerknechtM RudeliusS SauerS BraunPlatelet adhesion via glycoprotein IIb integrin is critical for atheroprogression and focal cerebral ischemia: an in vivo study in mice lacking glycoprotein IIbCirculation11211801188200510.1161/CIRCULATIONAHA.105.53922116103235

42. 

S MassbergI KonradK SchurzingerM LorenzS SchneiderD ZohlnhoeferPlatelets secrete stromal cell-derived factor1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivoJ Exp Med20312211233200610.1084/jem.2005177216618794

43. 

K HiasaM IshibashiK OhtaniS InoueQ ZhaoS KitamotoGene transfer of stromal cell-derived factor-1alpha enhances ischemic vasculogenesis and angiogenesis via vascular endothelial growth factor/endothelial nitric oxide synthase related pathway: next-generation chemokine therapy for therapeutic neovascularizationCirculation109245424612004

44. 

A AicherC HeeschenC Mildner-RihmC UrbichC IhlingK Technau-IhlingAM ZeiherS DimmelerEssential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cellsNat Med913701376200310.1038/nm94814556003

45. 

L LaterveerIJ LindleyMS HamiltonR WillemzeWE FibbeInterleukin-8 induces rapid mobilization of hematopoietic stem cells with radioprotective capacity and long term myelolymphoid repopulating abilityBlood852269227519957718900

46. 

L LaterveerJM ZijlemansIJ LindleyMS HamiltonR WillemzeWE FibbeImproved survival of lethally irradiated recipient mice transplanted with circulating progenitor cells mobilized by IL-8 after pretreatment with stem cell factorExp Hematol241387139319968913284

47. 

RM PalmerAG FerrigeS MoncadaNitric oxide release accounts for the biological activity of endothelium-derived relaxing factorNature327524526198710.1038/327524a03495737

48. 

JA WareDD HeistadSeminars in medicine of the Beth Israel Hospital, Boston. Platelet-endothelium interactionsN Engl J Med328628635199310.1056/NEJM1993030432809078429855

49. 

LJ GoldsteinKA GallagherSM BauerRJ BauerV BaireddyZJ LiuDG BuerkSR ThomOC VelazquezEndothelial progenitor cell release into circulation is triggered by hyperoxia-induced increases in bone marrow nitric oxideStem Cells2423092318200610.1634/stemcells.2006-001016794267

50. 

SR ThomVM BhopaleOC VelazquezLJ GoldsteinLH ThomDG BuerkStem cell mobilization by hyperbaric oxygenAm J Physiol Heart Circ Physiol290H1378H1386200610.1152/ajpheart.00888.200516299259

51. 

OW GriffithDJ StuehrNitric oxide synthases: properties and catalytic mechanismAnnu Rev Physiol57707736199510.1146/annurev.ph.57.030195.0034237539994

52. 

MA MarlettaAR HurshmanKM RuscheCatalysis by nitric oxide synthaseCurr Opin Chem Biol2656663199810.1016/S1367-5931(98)80098-7

53. 

Z LaczaM PuskarJP FigueroaJ ZhangN RajapakseDW BusijaMitochondrial nitric oxide synthase is constitutively active and is functionally upregulated in hypoxiaFree Radic Biol Med3116091615200110.1016/S0891-5849(01)00754-711744335

54. 

KA GallagherZL LiuM XiaoH ChenDiabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1αJ Clin Invest11712491259200717476357

55. 

SK GuptaPG LyskoK PillarisettiE OhlsteinJM StadelChemokine receptors in human endothelial cells. Functional expression of CXCR4 and its transcriptional regulation by inflammatory cytokinesJ Biol Chem27342824287199810.1074/jbc.273.7.42829461627

56. 

S BhaktaP HongO KocThe surface adhesion molecule CXCR4 stimulates mesenchymal stem cell migration to stromal cell-derived factor-1 in vitro but does not decrease apoptosis under serum deprivationCardiovasc Revasc Med71924200610.1016/j.carrev.2005.10.008

57. 

M KuciaR RecaK MiekusJ WanzeckW WojakowskiA Janowska-WieczorekJ RatajczakMZ RatajczakTrafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axisStem Cells23879894200510.1634/stemcells.2004-034215888687

58. 

T LapidotMechanism of human stem cell migration and repopulation of NOD/SCID and B2m Null NOD/SCID mouse: the role of SDF-1/CXCR4 interactionsAnn NY Acad Sci9388395200110.1111/j.1749-6632.2001.tb03577.x11458529

59. 

H ZhengG FuT DaiH HuangMigration of endothelial progenitor cells mediated by stromal cell-derived factor-1alpha/CXCR4 via PI3K/Akt/eNOS signal transduction pathwayJ Cardiovasc Pharmacol50274280200710.1097/FJC.0b013e318093ec8f17878755

60. 

S AkiraT TagaT KishimotoInterleukin-6 in biology and medicineAdv Immunol54178199310.1016/S0065-2776(08)60532-5

61. 

M HibiK NakajimaT HiranoIL-6 cytokine family and signal transduction: a model of the cytokine systemJ Mol Med74112199610.1007/BF002020688834766

62. 

D KamimuraK IshiharaT HiranoTransduction and its physiological roles: the signal orchestration modelRev Physiol Biochem Pharmacol149138200310.1007/s10254-003-0012-212687404

63. 

MB NilssonRR LangleyIJ FidlerInterleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokineCancer Res651079410800200510.1158/0008-5472.CAN-05-062316322225

64. 

Z WangWH NewmanSmooth muscle cell migration stimulated by interleukin-6 is associated with cytoskeletal reorganizationJ Surg Res111261266200310.1016/S0022-4804(03)00087-812850472

65. 

JS YaoW ZhaiWL YoungGY YangInterleukin-6 triggers human cerebral endothelial cells proliferation and migration: the role for KDR and MMP-9Biochem Biophys Res Commun34213961404200610.1016/j.bbrc.2006.02.10016516857

66. 

Y FanY YeF ShenInterleukin-6 stimulates circulating blood-derived endothelial progenitor cell angiogenesis in vitroJ Cereb Blood Flow Metab289098200810.1038/sj.jcbfm.960050917519976

67. 

M BartoliD PlattT LemtalsiX GuSE BrooksMB MarreroRB CaldwellVEGF differentially activates STAT3 in microvascular endothelial cellsFASEB J1715621564200312824281

68. 

DD DeoTW AxelradEG RobertV MarcheselliNG BazanJD HuntPhosphorylation of STAT-3 in response to basic fibroblast growth factor occurs through a mechanism involving platelet-activating factor, JAK-2, and Src in human umbilical vein endothelial cells. Evidence for a dual kinase mechanismJ Biol Chem2772123721245200210.1074/jbc.M110955200

69. 

IU SchraufstatterJ ChungM BurgerIL-8 activates endothelial cell CXCR1 and CXCR2 through Rho and Rac signaling pathwaysAm J Physiol Lung Cell Mol Physiol280L1094L1103200111350788

70. 

C HeissML WongWI BlockD LaoMW RealY YeghiazariansRL LeeML SpringerPleiotrophin induces nitric oxide dependent migration of endothelial progenitor cellsJ Cell Physiol215366373200810.1002/jcp.2131317960557

71. 

TD PollardGG BorisyCellular motility driven by assembly and disassembly of actin filamentsCell112453465200310.1016/S0092-8674(03)00120-X12600310

72. 

C RevenuR AthmanS RobineD LouvardThe coworkers of actin filaments: from cell structures to signalsNat Rev Mol Cell Biol5635646200410.1038/nrm143715366707

73. 

J WeiY LiuM ChangCL SunDW LiZQ LiuLS HuProteomic analysis of oxidative modification in endothelial colony-forming cells treated by hydrogen peroxideInt J Mol Med2910991105201222446847

74. 

N WernerJ PrillerU LaufsM EndresM BohmU DirnaglG NickenigBone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitionArterioscler Thromb Vasc Biol2215671572200210.1161/01.ATV.0000036417.43987.D8

75. 

M SataA SaiuraA KunisatoA TojoS OkadaT TokuhisaH HiraiM MakuuchiY HirataR NagaiHematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosisNat Med8403409200210.1038/nm0402-40311927948

76. 

D SimperPG StalboergerCL PanettaS WangNM CapliceSmooth muscle progenitor cells in human bloodCirculation10611991204200210.1161/01.CIR.0000031525.61826.A812208793

77. 

K ShimizuS SugiyamaM AikawaY FukumotoE RabkinP LibbyRN MitchellHost bone-marrow cells are a source of donor intimal smooth-muscle-like cells in murine aortic transplant arteriopathyNat Med7738741200111385513

78. 

JD AbbottY HuangD LiuR HickeyDS KrauseFJ GiordanoStromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injuryCirculation11033003305200410.1161/01.CIR.0000147780.30124.CF15533866

79. 

A SchoberS KnarrenM LietzEA LinC WeberCrucial role of stromal cell-derived factor-1alpha in neointima formation after vascular injury in apolipoprotein E deficient miceCirculation10824912497200310.1161/01.CIR.0000099508.76665.9A14581398

80. 

A ZerneckeA SchoberI BotP von HundelshausenEA LiehnB MoppsM MericskayP GierschikEA BiessenC WeberSDF-1alpha/CXCR4 axis is instrumental in neointimal hyperplasia and recruitment of smooth muscle progenitor cellsCirc Res96784791200510.1161/01.RES.0000162100.52009.3815761195

81. 

E ChavakisA AicherC HeeschenRole of beta2-integrins for homing and neovascularization capacity of endothelial progenitor cellsJ Exp Med2016372200510.1084/jem.2004140215623573

82. 

E ChavakisA HainM VinciG CarmonaME BianchiP VajkoczyHigh mobility group box1 activates integrin dependent homing of endothelial progenitor cellsCirc Res100204212200710.1161/01.RES.0000257774.55970.f417218606

83. 

B DelormeA BasireC GentileF SabatierF MonsonisC DesouchesPresence of endothelial progenitor cells, distinct from mature endothelial cells, within human CD146+ blood cellsThromb Haemost9412701279200516411405

84. 

T BombeliBR SchwartzJM HarlanAdhesion of activated platelets to endothelial cells: evidence for a GPIIbIIIa-dependent bridging mechanism and novel roles for endothelial intercellular adhesion molecule 1 (ICAM-1), alphavbeta3 integrin, and GPIbalphaJ Exp Med187329339199810.1084/jem.187.3.329

85. 

H JinA AiyerJ SuP BorgstromD StupackM FriedlanderJ VarnerA homing mechanism for bone marrow-derived progenitor cell recruitment to the neovasculatureJ Clin Invest116652662200610.1172/JCI2475116498499

86. 

G QinM IiM SilverA WeckerE BordH MaFunctional disruption of alpha4 integrin mobilizes bone marrow derived endothelial progenitors and augments ischemic neovascularizationJ Exp Med203153163200610.1084/jem.20050459

87. 

A KawamotoHC GwonH IwaguroJI YamaguchiS UchidaH MasudaM SilverH MaM KearneyJM IsnerT AsaharaTherapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemiaCirculation103634637200110.1161/01.CIR.103.5.63411156872

88. 

C UrbichC HeeschenA AicherE DernbachAM ZeiherS DimmelerRelevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cellsCirculation10825112516200310.1161/01.CIR.0000096483.29777.5014581410

89. 

A KawamotoT TkebuchavaJ YamaguchiH NishimuraYS YoonC MillikenS UchidaO MasuoH IwaguroH MaIntramyocardial transplantation of autologous endothelial progenitor cells for therapeutic neovascularization of myocardial ischemiaCirculation107461468200310.1161/01.CIR.0000046450.89986.50

90. 

T MuroharaH IkedaJ DuanS ShintaniK SasakiH EguchiI OnitsukaK MatsuiT ImaizumiTransplanted cord blood derived endothelial precursor cells augment postnatal neovascularizationJ Clin Invest10515271536200010.1172/JCI829610841511

91. 

E Tateishi-YuyamaH MatsubaraT MuroharaU IkedaS ShintaniH MasakiK AmanoY KishimotoK YoshimotoH AkashiTherapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trialLancet360427435200210.1016/S0140-6736(02)09670-8

92. 

B AssmusV SchächingerC TeupeM BrittenR LehmannN DöbertF GrünwaldA AicherC UrbichH MartinD HoelzerS DimmelerAM ZeiherTransplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI)Circulation10630093017200210.1161/01.CIR.0000043246.74879.CD

93. 

JC KovacicJ MooreA HerbertD MaM BoehmRM GrahamEndothelial progenitor cells, angioblasts, and angiogenesis: old terms reconsidered from a current perspectiveTrends Cardiovasc Med184551200810.1016/j.tcm.2007.12.00218308194

94. 

KK HirschiDA IngramMC YoderAssessing identity, phenotype, and fate of endothelial progenitor cellsArterioscler Thromb Vasc Biol2815841595200810.1161/ATVBAHA.107.15596018669889

95. 

CE MurryMH SoonpaaH ReineckeHaematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarctsNature428664668200410.1038/nature0244615034593

96. 

LB BalsamAJ WagersJL ChristensenT KofidisIL WeissmanRC RobbinsHaematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardiumNature428668673200410.1038/nature0246015034594

97. 

E KamoshitaY IkedaM FujitaH AmanoA OikawaRecruitment of a prostaglandin E receptor subtype, EP3-expressing bone marrow cells is crucial in wound-induced angiogenesisAm J Pathol16914581472200610.2353/ajpath.2006.05135817003499

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Li D, Liu Z, Wei J, Liu Y and Hu L: Contribution of endothelial progenitor cells to neovascularization (Review). Int J Mol Med 30: 1000-1006, 2012.
APA
Li, D., Liu, Z., Wei, J., Liu, Y., & Hu, L. (2012). Contribution of endothelial progenitor cells to neovascularization (Review). International Journal of Molecular Medicine, 30, 1000-1006. https://doi.org/10.3892/ijmm.2012.1108
MLA
Li, D., Liu, Z., Wei, J., Liu, Y., Hu, L."Contribution of endothelial progenitor cells to neovascularization (Review)". International Journal of Molecular Medicine 30.5 (2012): 1000-1006.
Chicago
Li, D., Liu, Z., Wei, J., Liu, Y., Hu, L."Contribution of endothelial progenitor cells to neovascularization (Review)". International Journal of Molecular Medicine 30, no. 5 (2012): 1000-1006. https://doi.org/10.3892/ijmm.2012.1108
Copy and paste a formatted citation
x
Spandidos Publications style
Li D, Liu Z, Wei J, Liu Y and Hu L: Contribution of endothelial progenitor cells to neovascularization (Review). Int J Mol Med 30: 1000-1006, 2012.
APA
Li, D., Liu, Z., Wei, J., Liu, Y., & Hu, L. (2012). Contribution of endothelial progenitor cells to neovascularization (Review). International Journal of Molecular Medicine, 30, 1000-1006. https://doi.org/10.3892/ijmm.2012.1108
MLA
Li, D., Liu, Z., Wei, J., Liu, Y., Hu, L."Contribution of endothelial progenitor cells to neovascularization (Review)". International Journal of Molecular Medicine 30.5 (2012): 1000-1006.
Chicago
Li, D., Liu, Z., Wei, J., Liu, Y., Hu, L."Contribution of endothelial progenitor cells to neovascularization (Review)". International Journal of Molecular Medicine 30, no. 5 (2012): 1000-1006. https://doi.org/10.3892/ijmm.2012.1108
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team