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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2012 Volume 30 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

microRNAs and thyroid cancer: Biological and clinical significance (Review)

Giulia Costanza Leonardi, Saverio Candido, Maurizio Carbone, Valeria Colaianni, Sebastiano F. Garozzo, Diana Cinà, Massimo Libra
Pages: 991-999
Published online on: 08 August 2012

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Review

Contribution of endothelial progenitor cells to neovascularization (Review)

Da-Wei Li, Zhi-Qiang Liu, Jun Wei, Ying Liu, Lin-Sen Hu
Pages: 1000-1006
Published online on: 23 August 2012

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Article Open Access

Oxidative stress caused by a low concentration of hydrogen peroxide induces senescence-like changes in mouse gingival fibroblasts

Tamotsu Kiyoshima, Norio Enoki, Ieyoshi Kobayashi, Takako Sakai, Kengo Nagata, Hiroko Wada, Hiroaki Fujiwara, Yukiko Ookuma, Hidetaka Sakai
Pages: 1007-1012
Published online on: 20 August 2012

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Article Open Access

miR-183 inhibits the metastasis of osteosarcoma via downregulation of the expression of Ezrin in F5M2 cells

Haien Zhao, Mingjun Guo, Guangyi Zhao, Qiong Ma, Baoan Ma, Xiuchun Qiu, Qingyu Fan
Pages: 1013-1020
Published online on: 24 August 2012

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Article Open Access

Curcumin inhibits HCV replication by induction of heme oxygenase-1 and suppression of AKT

Ming-Ho Chen, Ming-Yang Lee, Jing-Jing Chuang, Yi-Zhen Li, Sin-Tzu Ning, Jung-Chou Chen, Yi-Wen Liu
Pages: 1021-1028
Published online on: 20 August 2012

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Article Open Access

ERG is specifically associated with ETS-2 and ETV-4, but not with ETS-1, in prostate cancer

David Adler, Jacqueline Ochsenfahrt, Kerstin Fuchs, Glen Kristiansen, Sven Perner, Nicolas Wernert
Pages: 1029-1033
Published online on: 20 August 2012

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Article Open Access

Gastrodin inhibits cell proliferation in vascular smooth muscle cells and attenuates neointima formation in vivo

Lihua Zhu, Hongjing Guan, Changping Cui, Song Tian, Da Yang, Xinan Wang, Shuming Zhang, Lang Wang, Hong Jiang
Pages: 1034-1040
Published online on: 20 August 2012

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Article Open Access

A novel double antibody sandwich-lateral flow immunoassay for the rapid and simple detection of hepatitis C virus

Tingxiu Xiang, Zheng Jiang, Jian Zheng, Chaoyu Lo, Harry Tsou, Guosheng Ren, Jun Zhang, Ailong Huang, Guoqi Lai
Pages: 1041-1047
Published online on: 06 September 2012

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Article

Mutations in non-structural 5A and rapid viral response to pegylated interferon-α-2b plus ribavirin therapy are associated with therapeutic efficacy in patients with genotype 1b chronic hepatitis C

Yoshihiko Yano, Yasushi Seo, Akira Miki, Masaya Saito, Hirotaka Kato, Ken-Ichi Hamano, Manabu Oya, Sachiko Ouchi, Takashi Fujisawa, Hajime Yamada, Yukimasa Yamashita, Satoshi Tani, Shigeya Hirohata, Seitetsu Yoon, Naoto Kitajima, Kazunari Kitagaki, Akira Kawara, Takatoshi Nakashima, Hosai Yu, Tetsuo Maeda, Takeshi Azuma, Ahmed El-Shamy, Hak Hotta, Yoshitake Hayashi, Kobe Hepatitis Therapeutic Group
Pages: 1048-1052
Published online on: 09 August 2012

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Article

Evaluation of the interactions of HIV-1 integrase with small ubiquitin-like modifiers and their conjugation enzyme Ubc9

Zhihui Li, Shuwen Wu, Jingjing Wang, Wenjuan Li, Yun Lin, Chaoneng Ji, Jinglun Xue, Jinzhong Chen
Pages: 1053-1060
Published online on: 08 August 2012

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Article

Evaluation of serum diagnosis of pancreatic cancer by using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry

Hongjun Gao, Zhaoxu Zheng, Zhigang Yue, Fang Liu, Lanping Zhou, Xiaohang Zhao
Pages: 1061-1068
Published online on: 30 August 2012

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Article

Insulin-like growth factor-1 protects against prion peptide-induced cell death in neuronal cells via inhibition of Bax translocation

Yang-Gyu Park, Jae-Kyo Jeong, Myung-Hee Moon, Ju-Hee Lee, You-Jin Lee, Jae-Won Seol, Shang-Jin Kim, Seog-Jin Kang, Sang-Youel Park
Pages: 1069-1074
Published online on: 08 August 2012

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Article

Glycosaminoglycan chains of biglycan promote bone morphogenetic protein-4-induced osteoblast differentiation

Yaping Ye, Weihua Hu, Fengjing Guo, Weikai Zhang, Jiang Wang, Anmin Chen
Pages: 1075-1080
Published online on: 09 August 2012

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Article

Genistein demethylates the promoter of CHD5 and inhibits neuroblastoma growth in vivo

Hui Li, Weijue Xu, Yimin Huang, Xiong Huang, Lingcang Xu, Zhibao Lv
Pages: 1081-1086
Published online on: 06 September 2012

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Article

The synergistic effects of low-dose irinotecan and TRAIL on TRAIL-resistant HT-29 colon carcinoma in vitro and in vivo

Hong Zhu, Fen Zhao, Shuijing Yu, Jianping He, Licong Deng, Cheng Yi, Ying Huang
Pages: 1087-1094
Published online on: 21 August 2012

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Article

microRNA expression profiling of the developing mouse heart

Li Cao, Li-Ping Kong, Zhang-Bin Yu, Shu-Ping Han, Yun-Fei Bai, Jingai Zhu, Xiaoshan Hu, Chun Zhu, Shasha Zhu, Xi-Rong Guo
Pages: 1095-1104
Published online on: 09 August 2012

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Article

Sage weed (Salvia plebeia) extract antagonizes foam cell formation and promotes cholesterol efflux in murine macrophages

Sin-Hye Park, Jung-Lye Kim, Min-Kyung Kang, Ju-Hyun Gong, Seon-Young Han, Jae-Hoon Shim, Soon Sung Lim, Young-Hee Kang
Pages: 1105-1112
Published online on: 20 August 2012

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Article

PDGF-AA and bFGF mediate B104CM-induced proliferation of oligodendrocyte precursor cells

Jian-Guo Hu, Xing-Jun Wu, Yi-Fan Feng, Gang-Ming Xi, Zhen-Huan Wang, Jian-Sheng Zhou, He-Zuo Lü
Pages: 1113-1118
Published online on: 24 August 2012

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Article

RhoA/Rho kinase signaling regulates transforming growth factor-β1-induced chondrogenesis and actin organization of synovium-derived mesenchymal stem cells through interaction with the Smad pathway

Ting Xu, Mengjie Wu, Jianying Feng, Xinping Lin, Zhiyuan Gu
Pages: 1119-1125
Published online on: 23 August 2012

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Article

Hydrogen sulfide protects PC12 cells against reactive oxygen species and extracellular signal-regulated kinase 1/2-mediated downregulation of glutamate transporter-1 expression induced by chemical hypoxia

Liangcan Xiao, Aiping Lan, Liqiu Mo, Wenming Xu, Nan Jiang, Fen Hu, Jianqiang Feng, Changran Zhang
Pages: 1126-1132
Published online on: 08 August 2012

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Article

Fragments of SLIT3 inhibit cellular migration

Thomas Schubert, Alexandra E. Denk, Anke Ruedel, Simone Kaufmann, Elisabeth Hustert, Patrizia Bastone, Anja K. Bosserhoff
Pages: 1133-1137
Published online on: 20 August 2012

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Article

Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation Expression of Concern in /10.3892/ijmm.2026.5821

Keng Wu, Wenming Xu, Qiong You, Runmin Guo, Jianqiang Feng, Changran Zhang, Wen Wu
Pages: 1138-1144
Published online on: 20 August 2012

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Article

Decreased levels of Ca2+-calmodulin-dependent protein kinase IV in the testis as a contributing factor to reduced fertility in male Crybb2-/- mice

Fenfen Xiang, Bei Cui, Qian Gao, Jianrong Zhang, Junjie Zhang, Wenjie Li
Pages: 1145-1151
Published online on: 03 September 2012

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Article

Tacrolimus (FK506) suppresses TNF-α-induced CCL2 (MCP-1) and CXCL10 (IP-10) expression via the inhibition of p38 MAP kinase activation in human colonic myofibroblasts

Tomoki Aomatsu, Hirotsugu Imaeda, Kenichiro Takahashi, Takehide Fujimoto, Eiji  Kasumi, Atsushi Yoden, Hiroshi Tamai, Yoshihide Fujiyama, Akira Andoh
Pages: 1152-1158
Published online on: 10 August 2012

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Article

Protective effect of 7-difluoromethoxy-5,4'-Di-hydroxyl isoflavone against the damage induced by glutamate in PC12 cells

Xing Feng, Qin Zhou, Chong Liu, Mei-Ling Tao, Jian-Guo Cao, Zhi-Hong Zhong
Pages: 1159-1165
Published online on: 23 August 2012

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Article

Radiosensitization effects of berberine on human breast cancer cells

Jing Wang, Qiao Liu, Qifeng Yang
Pages: 1166-1172
Published online on: 10 August 2012

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Article

Hypoxia-regulated neurotrophin-3 expression by multicopy hypoxia response elements reduces apoptosis in PC12 cells

Junfeng Zhang, Qindong Shi, Xinlin Chen, Pengbo Yang, Cunfang Qi, Jianshui Zhang, Haixia Lu, Jianxin Liu, Qian Jiao, Lingyu Zhao, Bingqiao Zhao, Ping Zheng, Yong Liu
Pages: 1173-1179
Published online on: 06 September 2012

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Article

The hypoxia-mimetic agent cobalt chloride induces cell cycle arrest and alters gene expression in U266 multiple myeloma cells

Seunghee Bae, Hye-Jung Jeong, Hwa Jun Cha, Karam Kim, Yeong Min Choi, In-Sook An, Hyea Jung Koh, Dae Jin Lim, Su-Jae Lee, Sungkwan An
Pages: 1180-1186
Published online on: 31 August 2012

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Article

Chondrogenic ATDC5 cells: An optimised model for rapid and physiological matrix mineralisation

P. T. Newton, K. A. Staines, L. Spevak, A. L. Boskey, C. C. Teixeira, V. E. Macrae, A. E. Canfield, C. Farquharson
Pages: 1187-1193
Published online on: 31 August 2012

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Article

Titrated extract of Centella asiatica provides a UVB protective effect by altering microRNA expression profiles in human dermal fibroblasts

In-Sook An, Sungkwan An, Sang-Mo Kang, Tae-Boo Choe, Sung Nae Lee, Hyun Hee Jang, Seunghee Bae
Pages: 1194-1202
Published online on: 04 September 2012

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Article

Silk fibroin hydrolysate inhibits osteoclastogenesis and induces apoptosis of osteoclasts derived from RAW 264.7 cells

Jeon-Woo Chon, Hyeryeon Kim, Ha-Na Jeon, Kyungho Park, Kwang-Gill Lee, Joo-Hong Yeo, Haeyong Kweon, Heui-Sam Lee, You-Young Jo, Yoo Kyoung Park
Pages: 1203-1210
Published online on: 06 September 2012

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Article

Antiproliferative and apoptotic effect of epigallocatechin-3-gallate on Ishikawa cells is accompanied by sex steroid receptor downregulation

Seung Bin Park, Jong Woon Bae, Jong Min Kim, Seung Gee Lee, Myoungseok Han
Pages: 1211-1218
Published online on: 20 August 2012

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Article

Anti-adipogenic effects of 1,25-dihydroxyvitamin D3 are mediated by the maintenance of the wingless-type MMTV integration site/β-catenin pathway

Haeyong Lee, Sungmin Bae, Yoosik Yoon
Pages: 1219-1224
Published online on: 20 August 2012

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Article

Single impact cartilage trauma and TNF-α: Interactive effects do not increase early cell death and indicate the need for bi-/multidirectional therapeutic approaches

Cathrin Hogrefe, Helga Joos, Vennila Maheswaran, Lutz Dürselen, Anita Ignatius, Rolf E. Brenner
Pages: 1225-1232
Published online on: 24 August 2012

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Article

Calbindin-D9k as a sensitive molecular biomarker for evaluating the synergistic impact of estrogenic chemicals on GH3 rat pituitary cells

Thuy T.B. Vo, Beum-Soo An, Hyun Yang, Eui-Man Jung, Inho Hwang, Eui-Bae Jeung
Pages: 1233-1240
Published online on: 06 September 2012

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Article

Isoform-specific alanine aminotransferase measurement can distinguish hepatic from extrahepatic injury in humans

Ingalill Rafter, Truls Gråberg, Anna Kotronen, Lovisa Strömmer, C. Mikael Mattson, Ray W. Kim, Ewa Ehrenborg, Håkan B. Andersson, Hannele Yki-Järvinen, Ina Schuppe-Koistinen, Björn Ekblom, Ian Cotgreave, Björn Glinghammar
Pages: 1241-1249
Published online on: 23 August 2012

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Journal Cover
November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Spatial multi‑omics identifies an SPP1+ macrophage‑driven anti‑apoptotic niche in osteoarthritis synovium via the SPP1‑CD44 axis

Han Gong, Hao Shen, Feng Zhang, Wei Wang, Sheng Zhou, Lei Wang, Yu Sun
Article Number: 334
Published online on: 29 September 2026

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Review Open Access

Novel insights into the role of the renal interstitial microenvironment in Randall's plaque formation (Review)

Jialiang Wang, Zhangcheng Liao, Minghui Liu, Yizhou Wang, Yu Cui, Hequn Chen, Feng Zeng, Zewu Zhu
Article Number: 333
Published online on: 29 September 2026

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Correction Open Access

[Corrigendum] Alteration of the Wnt/GSK3β/β‑catenin signalling pathway by rapamycin ameliorates pathology in an Alzheimer's disease model

Jingfei Chen, Zhimin Long, Yanzhen Li, Min  Luo, Shifang  Luo, Guiqiong He
Article Number: 332
Published online on: 28 September 2026

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Article Open Access

miR‑222‑3p inhibits diabetic skin wound healing by targeting APLN

Ruyan Jie, Ying Tang, Tingting Wu, Chenfan Zhang, Man Song, Xiaotong Zhao, Mingwei Chen
Article Number: 331
Published online on: 25 September 2026

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Correction Open Access

[Corrigendum] Adjudin delays cellular senescence through Sirt3‑mediated attenuation of ROS production

Keyi Geng, Ningzhen Fu, Xiao Yang, Weiliang Xia
Article Number: 330
Published online on: 23 September 2026

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Article Open Access

Salidroside attenuates myocardial ischemia‑reperfusion‑induced oxidative stress and ferroptosis by promoting USP11‑mediated  deubiquitination of PRDX2

Zhi-Cong Qiu, Jian-Nan Li, Yi-Zhou Li, Zi-Ming Wu, Xu-Dong Luo, Rui-Yuan Zeng, Song-Qing Lai, Shi-Tao Zhao, Li Wan
Article Number: 329
Published online on: 23 September 2026

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Review Open Access

Reprogramming of cell death in gastric cancer: From molecular mechanisms to therapeutic potential (Review)

Mengru Liu, Zhujun Wu, Qiao Chen, Weiguo Ni, Ying Chen, Yixin Zhu, Yu Chen, Haifeng Ma, Yan Lin
Article Number: 328
Published online on: 23 September 2026

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Article Open Access

Remimazolam attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis involving the AKT/SLC7A11/GPX4 axis

Xiyuan Chen, Jianghong Zhao, Xingtong He, Yuqi Zhang, Jiao Wu, Chao Jiang, Yi Yang, Ji Xiao
Article Number: 327
Published online on: 22 September 2026

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Review Open Access

Tumor‑immune spatiotemporal co‑evolution: A new paradigm for understanding and overcoming therapy resistance in metastatic castration‑resistant prostate cancer (Review)

Li Yan, Xiaoke Sun, Pengxiao Su
Article Number: 326
Published online on: 21 September 2026

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Review Open Access

Research progress on the role of IL‑37 in gynecological and obstetrics‑related diseases (Review)

Hongjing Wang, Renukha Arjune, Weiyu Gan, Na Guo, Nan Yu, Ting Xiong
Article Number: 325
Published online on: 21 September 2026

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Expression of Concern Open Access

[Expression of Concern] PAT protein mRNA expression in primary rat hepatocytes: Effects of exposure to fatty acids

Elena Grasselli, Adriana Voci, Carlo Pesce, Laura Canesi, Emilia Fugassa, Gabriella Gallo, Laura Vergani
Article Number: 324
Published online on: 21 September 2026

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Review Open Access

Neutrophil extracellular traps in cardiovascular disease: Mechanisms and therapeutic implications (Review)

Zhao Wang, Mingde Chang, Wenyu Shang, Yunfeng Jia, Xiaoyu Shan, Xinnong Chen, Yingxi Yang, Junping Zhang
Article Number: 323
Published online on: 18 September 2026

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Article Open Access

Sirt1 attenuates calcific aortic valve disease by inhibiting ferroptosis and enhancing mitochondrial function via the activation of the Nrf2/HO‑1/FTH1 axis

Fei Yan, Lei Shi, Yuechan Wang, Ying Zhao, Yuanyuan Wu, Dubiao Xian, Yunheng Liang, Ning Wang, Hongwang Cui, Minni Zhang
Article Number: 322
Published online on: 18 September 2026

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Article Open Access

Ketogenic diet attenuates Müller cell activation and retinal neuroinflammation in autoimmune glaucoma through acetylation‑mediated FOXO signalling

Sisi Tan, Xiaochen Wang, Yunfan Zheng, Zhenni Mou, Lihong Zeng, Jingchang Yuan, Xiao Fan, Miao Wei, Yujia Huo, Ruotong Ouyang, Yanyu Pu, Junqin Lei, Xi Gao, Dangdang Wang, Yang Peng, Hong Li
Article Number: 321
Published online on: 17 September 2026

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Review Open Access

ILC3s as central regulators of mucosal homeostasis and disease pathogenesis (Review)

Jingwen Zhang, Lili Bao, Jiaxi Li, Xia Li, Lu Qiao, Jiaxian Cui, Xiaoxia He, Mingyu Zhang, Jingkun Lu, Xuan Zhang, Jing Dong, Gesi Tao, Yaoqing Feng, Yun Peng Tian, Pengwei Zhao, Ya Tuo
Article Number: 320
Published online on: 17 September 2026

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Review Open Access

Small extracellular vesicles in osteoarthritis: A double‑edged sword regulating inflammation and cartilage homeostasis (Review)

Yifan Yang, Jiachen Liang, Xiangyu Shi, Anqi Niu, Ruifang Gao, Xiuping Wu, Xiaojuan Guo, Xiaotong Shi, Kejie Cao, Bing Li, Ran Li
Article Number: 319
Published online on: 17 September 2026

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Review Open Access

Exosomal circular RNAs in the tumor immune microenvironment: From regulatory mechanisms to therapeutic opportunities and translational hurdles (Review)

Wenlong Zhang, Nuo Chen, Liya Gong, Yu Dong, Hui Shen, Xin Liu, Jie Sun, Luxuan Liu, Zhe Jin, Liaoyuan Wang, Xue Han, Bin Zhang, Shuixing Zhang
Article Number: 318
Published online on: 17 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ginsenoside Rg1 protects against H2O2‑induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro

Tan-Zhen Xu, Xiao-Yan Shen, Ling-Ling Sun, Ya-Li Chen, Bi-Qiong Zhang, Da-Ke Huang, Wei-Zu Li
Article Number: 317
Published online on: 16 September 2026

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Review Open Access

tRNA‑derived RNAs in hepatic diseases: From biological functions to clinical translation (Review)

Yaotian Cai, Yifei Chen, Fuji Yang, Yongmin Yan, Ting Jiang
Article Number: 316
Published online on: 15 September 2026

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Review Open Access

Monocytes in pneumonia: Functional plasticity and innate memory (Review) 

Run-Ze Li, Zhi-Han Xie, Li Chen, Yun-Xiao Shang, Fei Wang, Wan-Jie Huang, Qi Cheng
Article Number: 315
Published online on: 15 September 2026

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Correction Open Access

[Corrigendum] Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis

Hao Lin, Xinran Cheng, Yangyang Ren, Yongmei Zhang, Weixu Chen, Qingyan Lu, Yiqing Tian
Article Number: 314
Published online on: 14 September 2026

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Review Open Access

Ferroptosis in heatstroke: Mechanisms and therapeutic perspectives (Review)

Hongguang Gao, Yang Chen, Tianshan Zhang, Yujun Shi, Rong Yao
Article Number: 313
Published online on: 10 September 2026

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Correction Open Access

[Corrigendum] Inactivation of von Hippel‑Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR‑210/VMP1 signaling pathway

Ting Liu, Le Zhao, Wei Chen, Zhen Li, Huilian Hou, Lu Ding, Xu Li
Article Number: 312
Published online on: 10 September 2026

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Review Open Access

Interferon regulatory factors orchestrate CD8+ T cell function (Review)

Fa-Xi Wang, Chun-Liang Yang, Shan-Jie Rong, Qi-Jie Chen, Xiong-Tao Yue, Fei Sun
Article Number: 311
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Rapamycin‑induced miR‑30a downregulation inhibits senescence of VSMCs by targeting Beclin1

Pan Tan, Haiqin Wang, Junkun Zhan, Xinyu Ma, Xingjun Cui, Yanjiao Wang, Yi Wang, Jiayu Zhong, Youshuo Liu
Article Number: 310
Published online on: 07 September 2026

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Review Open Access

Deciphering the function and mechanism of extracorporeal shock wave therapy in knee osteoarthritis (Review)

Yixuan Chen, Siqi Song, Yuchen Zhu, Shiqi Wang, Jieyuan Hu, Chenxu Liu, Yuchen Cai, Yushi Hu
Article Number: 309
Published online on: 04 September 2026

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Review Open Access

Multi‑omics integration in osteoarthritis: Unraveling cell‑type‑specific gene‑metabolite networks for precision medicine (Review)

Ying Yang, Ruichen Zheng, Yun Zhang, Dongmei Ye, Jiale Xie, Changliang Zhu
Article Number: 308
Published online on: 03 September 2026

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Review Open Access

Autophagy determines the fate of immune cells by regulating metabolic remodeling and PANoptosis (Review)

Yanan Guo, Xinyue Zhou, Yixiao Tian, Dan Chen, Xiaofeng Xie, Bin Zhou, Yingxia Tian, Yaqing Zhang
Article Number: 307
Published online on: 03 September 2026

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Review Open Access

Programmed cell death in metabolic syndrome: From molecular mechanisms to therapeutic strategies (Review)

Jialin Zhong, Maofu Zhang, Yafang Zheng, Cuicui Gong, Yasheng Deng, Lisha Sun, Dongqi Zhou, Qian Zhou, Qiu Chen
Article Number: 306
Published online on: 03 September 2026

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Review Open Access

Research progress on lysine acetylation (Review)

Minghui Zhang, Yuqi Zhang, Haoxin Yin, Junyuan Yan, Yingling Dong, Xin Zhao, Tianyi Cui, Bin Lv, Xiumei Gao
Article Number: 305
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Human ether‑à‑go‑go‑related gene mutation L539fs/47‑hERG leads to cell apoptosis through the endoplasmic reticulum stress pathway

Shuting Ma, Yun Zhao, Miaomiao Cao, Chaofeng Sun
Article Number: 304
Published online on: 02 September 2026

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Review Open Access

Targeting integrated cell death networks in sepsis‑associated acute kidney injury: Shared regulatory nodes and diet‑related small molecule modulation (Review)

Lin Song, Aifeng He, Wei Jiang, Keran Shi, Jing Wang, Lu Xu, Jiangquan Yu, Ruiqiang Zheng
Article Number: 303
Published online on: 31 August 2026

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Article Open Access

Effect of MALT1 inhibition by MI‑2 on the microglial phenotype switch, inflammatory cytokine secretion, neuronal loss and oxidative stress in Alzheimer's disease

Yuanlong Li, Hua Fan, Xiong Han, Ming Ni, Xiaodan Hou, Hailan Xia, Yinzhu Shi, Lin Zhang, Jun Sun
Article Number: 302
Published online on: 31 August 2026

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Review Open Access

Salvianolic acid monomers against metastasis: Decoding the multilayered interception of EMT, angiogenesis and immune evasion (Review)

Shiting Jiang, Dan Liu, Tingting Wei, Qiwei Shi, Haowen Wang, Yidan Gao, Pingsu Mao, Wenli Yang
Article Number: 301
Published online on: 31 August 2026

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Retraction Open Access

[Retracted] Silencing of decoy receptor 3 (DcR3) expression by siRNA in pancreatic carcinoma cells induces Fas ligand‑mediated apoptosis in vitro and in vivo

Jian Zhou, Shiduo Song, Songbin He, Zhenxin Wang, Bing Zhang, Dechun Li, Dongming Zhu
Article Number: 300
Published online on: 31 August 2026

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Review Open Access

Research progress on BTG2 in non‑tumor diseases (Review)

Shuling Li, Xiaomei Liu, Zheng Zhang, Ling Yang, Yuxuan Li, Qiongdan Hu
Article Number: 299
Published online on: 28 August 2026

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Review Open Access

Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Review Open Access

Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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December-2026 Volume 58 Issue 6

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Anesthetics and cancer biology: Translational evidence from perioperative modulation to drug repurposing (Review)

Ting Yang, Jiao Tang, Muhammad Saqib Mudabbar, Huan Hu, Qiang Fu, Chunlan Pu
Article Number: 336
Published online on: 05 October 2026

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Expression of Concern Open Access

[Expression of Concern] Multiple roles of SOCS proteins: Differential expression of SOCS1 and SOCS3 in atherosclerosis

Xiao Liang, Ming He, Tao Chen, Yan Liu, Yu-Ling Tian, Yu-Liang Wu, Yan Zhao, Yan Shen, Zu-Yi Yuan
Article Number: 335
Published online on: 30 September 2026

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