|
1
|
Parker RG and Berry HC: Late effects of
therapeutic irradiation on the skeleton and bone marrow. Cancer.
37(Suppl 2): 1162–1171. 1976. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Baxter NN, Habermann EB, Tepper JE, Durham
SB and Virnig BA: Risk of pelvic fractures in older women following
pelvic irradiation. JAMA. 294:2587–2593. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Brown SA and Guise TA: Cancer
treatment-related bone disease. Crit Rev Eukaryot Gene Expr.
19:47–60. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Guise TA: Bone loss and fracture risk
associated with cancer therapy. Oncologist. 11:1121–1131. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Florin TA, Fryer GE, Miyoshi T, Weitzman
M, Mertens AC, Hudson MM, Sklar CA, Emmons K, Hinkle A, Whitton J,
Stovall M, Robison LL and Oeffinger KC: Physical inactivity in
adult survivors of childhood acute lymphoblastic leukemia: a report
from the childhood cancer survivor study. Cancer Epidemiol
Biomarkers Prev. 16:1356–1363. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Oeffinger KC, Mertens AC, Sklar CA,
Kawashima T, Hudson MM, Meadows AT, Friedman DL, Marina N, Hobbie
W, Kadan-Lottick NS, Schwartz CL, Leisenring W and Robison LL:
Childhood Cancer Survivor Study: chronic health conditions in adult
survivors of childhood cancer. N Engl J Med. 355:1572–1582. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Ergün H and Howland WJ: Postradiation
atrophy of mature bone. CRC Crit Rev Diagn Imaging. 12:225–243.
1980.
|
|
8
|
Hopewell JW: Radiation-therapy effects on
bone density. Med Pediatr Oncol. 41:208–211. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Howland WJ, Loeffler RK, Starchman DE and
Johnson RG: Postirradiation atrophic changes of bone and related
complications. Radiology. 117:677–685. 1975. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Mitchell MJ and Logan PM:
Radiation-induced changes in bone. Radiographics. 18:1125–1136.
1998. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Sams A: The effect of 2000 r of X-rays on
the internal structure of the mouse tibia. Int J Radiat Biol Relat
Stud Phys Chem Med. 11:51–68. 1966. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Dudziak ME, Saadeh PB, Mehrara BJ,
Steinbrech DS, Greenwald JA, Gittes GK and Longaker MT: The effects
of ionizing radiation on osteoblast-like cells in vitro. Plast
Reconstr Surg. 106:1049–1061. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Gal TJ, Munoz-Antonia T, Muro-Cacho CA and
Klotch DW: Radiation effects on osteoblasts in vitro: a potential
role in osteoradionecrosis. Arch Otolaryngol Head Neck Surg.
126:1124–1128. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Szymczyk KH, Shapiro IM and Adams CS:
Ionizing radiation sensitizes bone cells to apoptosis. Bone.
34:148–156. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Sakurai T, Sawada Y, Yoshimoto M, Kawai M
and Miyakoshi J: Radiation-induced reduction of osteoblast
differentiation in C2C12 cells. J Radiat Res. 48:515–521. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Geblinger D, Zink C, Spencer ND, Addadi L
and Geiger B: Effects of surface microtopography on the assembly of
the osteoclast resorption apparatus. J R Soc Interface.
9:1599–1608. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Willey JS, Lloyd SA, Nelson GA and Bateman
TA: Space radiation and bone loss. Gravit Space Biol Bull.
25:14–21. 2011.
|
|
18
|
Canalis E, Giustina A and Bilezikian JP:
Mechanisms of anabolic therapies for osteoporosis. N Engl J Med.
357:905–916. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Deregowski V, Gazzerro E, Priest L,
Rydziel S and Canalis E: Notch 1 overexpression inhibits
osteoblastogenesis by suppressing Wnt/beta-catenin but not bone
morphogenetic protein signaling. J Biol Chem. 281:6203–6210. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Gazzerro E and Canalis E: Bone
morphogenetic proteins and their antagonists. Rev Endocr Metab
Disord. 7:51–65. 2006. View Article : Google Scholar
|
|
21
|
Krishnan V, Bryant HU and Macdougald OA:
Regulation of bone mass by Wnt signaling. J Clin Invest.
116:1202–1209. 2006. View
Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wong BR, Rho J, Arron J, Robinson E,
Orlinick J, Chao M, Kalachikov S, Cayani E, Bartlett FS III,
Frankel WN, Lee SY and Choi Y: TRANCE is a novel ligand of the
tumor necrosis factor receptor family that activates c-Jun
N-terminal kinase in T cells. J Biol Chem. 272:25190–25194. 1997.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Caetano-Lopes J, Canhão H and Fonseca JE:
Osteoblasts and bone formation. Acta Reumatol Port. 32:103–110.
2007.
|
|
24
|
Zanotti S and Canalis E: Notch regulation
of bone development and remodeling and related skeletal disorders.
Calcif Tissue Int. 90:69–75. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Hori K, Sen A, Kirchhausen T and
Artavanis-Tsakonas S: Regulation of ligand-independent Notch signal
through intra-cellular trafficking. Commun Integr Biol. 5:374–376.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Schroeter EH, Kisslinger JA and Kopan R:
Notch-1 signalling requires ligand-induced proteolytic release of
intracellular domain. Nature. 393:382–386. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Iso T, Kedes L and Hamamori Y: HES and
HERP families: multiple effectors of the Notch signaling pathway. J
Cell Physiol. 194:237–255. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Zanotti S and Canalis E: Notch and the
skeleton. Mol Cell Biol. 30:886–896. 2010. View Article : Google Scholar
|
|
29
|
Quarles LD, Yohay DA, Lever LW, Caton R
and Wenstrup RJ: Distinct proliferative and differentiated stages
of murine MC3T3-E1 cells in culture: an in vitro model of
osteoblast development. J Bone Miner Res. 7:683–692. 1992.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Murshed M, Harmey D, Millán JL, McKee MD
and Karsenty G: Unique coexpression in osteoblasts of broadly
expressed genes accounts for the spatial restriction of ECM
mineralization to bone. Genes Dev. 19:1093–1104. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Sciaudone M, Gazzerro E, Priest L, Delany
AM and Canalis E: Notch 1 impairs osteoblastic cell
differentiation. Endocrinology. 144:5631–5639. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Kalajzic I, Kalajzic Z, Kaliterna M,
Gronowicz G, Clark SH, Lichtler AC and Rowe D: Use of type I
collagen green fluorescent protein transgenes to identify
subpopulations of cells at different stages of the osteoblast
lineage. J Bone Miner Res. 17:15–25. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Zanotti S, Smerdel-Ramoya A, Stadmeyer L,
Durant D, Radtke F and Canalis E: Notch inhibits osteoblast
differentiation and causes osteopenia. Endocrinology.
149:3890–3899. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Tao J, Chen S, Yang T, Dawson B, Munivez
E, Bertin T and Lee B: Osteosclerosis owing to Notch gain of
function is solely Rbpj-dependent. J Bone Miner Res. 25:2175–2183.
2010. View
Article : Google Scholar : PubMed/NCBI
|
|
35
|
Engin F, Yao Z, Yang T, Zhou G, Bertin T,
Jiang MM, Chen Y, Wang L, Zheng H, Sutton RE, Boyce BF and Lee B:
Dimorphic effects of Notch signaling in bone homeostasis. Nat Med.
14:299–305. 2008. View
Article : Google Scholar : PubMed/NCBI
|
|
36
|
Calvi LM, Adams GB, Weibrecht KW, Weber
JM, Olson DP, Knight MC, Martin RP, Schipani E, Divieti P,
Bringhurst FR, Milner LA, Kronenberg HM and Scadden DT:
Osteoblastic cells regulate the haematopoietic stem cell niche.
Nature. 425:841–846. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Pereira RM, Delany AM, Durant D and
Canalis E: Cortisol regulates the expression of Notch in
osteoblasts. J Cell Biochem. 85:252–258. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Schnabel M, Fichtel I, Gotzen L and
Schlegel J: Differential expression of Notch genes in human
osteoblastic cells. Int J Mol Med. 9:229–232. 2002.PubMed/NCBI
|
|
39
|
Luo B, Aster JC, Hasserjian RP, Kuo F and
Sklar J: Isolation and functional analysis of a cDNA for human
Jagged2, a gene encoding a ligand for the Notch1 receptor. Mol Cell
Biol. 17:6057–6067. 1997.PubMed/NCBI
|
|
40
|
Dallas DJ, Genever PG, Patton AJ,
Millichip MI, McKie N and Skerry TM: Localization of ADAM10 and
Notch receptors in bone. Bone. 25:9–15. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Nobta M, Tsukazaki T, Shibata Y, Xin C,
Moriishi T, Sakano S, Shindo H and Yamaguchi A: Critical regulation
of bone morphogenetic protein-induced osteoblastic differentiation
by Delta1/Jagged1-activated Notch1 signaling. J Biol Chem.
280:15842–15848. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Sethi N, Dai X, Winter CG and Kang Y:
Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast
cancer by engaging notch signaling in bone cells. Cancer Cell.
19:192–205. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Bai S, Kopan R, Zou W, Hilton MJ, Ong CT,
Long F, Ross FP and Teitelbaum SL: NOTCH1 regulates
osteoclastogenesis directly in osteoclast precursors and indirectly
via osteoblast lineage cells. J Biol Chem. 283:6509–6518. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Zhang J, Niu C, Ye L, Huang H, He X, Tong
WG, Ross J, Haug J, Johnson T, Feng JQ, Harris S, Wiedemann LM,
Mishina Y and Li L: Identification of the haematopoietic stem cell
niche and control of the niche size. Nature. 425:836–841. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Mancini SJ, Mantei N, Dumortier A, Suter
U, MacDonald HR and Radtke F: Jagged1-dependent Notch signaling is
dispensable for hematopoietic stem cell self-renewal and
differentiation. Blood. 105:2340–2342. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Zanotti S, Smerdel-Ramoya A and Canalis E:
HES1 (hairy and enhancer of split 1) is a determinant of bone mass.
J Biol Chem. 286:2648–2657. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Zhang Y, Lian JB, Stein JL, van Wijnen AJ
and Stein GS: The Notch-responsive transcription factor Hes-1
attenuates osteocalcin promoter activity in osteoblastic cells. J
Cell Biochem. 108:651–659. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Ito Y: Oncogenic potential of the RUNX
gene family: ‘overview’. Oncogene. 23:4198–4208. 2004.
|
|
49
|
Levanon D, Negreanu V, Bernstein Y, Bar-Am
I, Avivi L and Groner Y: AML1, AML2, and AML3, the human members of
the runt domain gene-family: cDNA structure, expression, and
chromosomal localization. Genomics. 23:425–432. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Banerjee C, McCabe LR, Choi JY, Hiebert
SW, Stein JL, Stein GS and Lian JB: Runt homology domain proteins
in osteoblast differentiation: AML3/CBFA1 is a major component of a
bone-specific complex. J Cell Biochem. 66:1–8. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Ducy P, Zhang R, Geoffroy V, Ridall AL and
Karsenty G: Osf2/Cbfa1: a transcriptional activator of osteoblast
differentiation. Cell. 89:747–754. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Harada H, Tagashira S, Fujiwara M, Ogawa
S, Katsumata T, Yamaguchi A, Komori T and Nakatsuka M: Cbfa1
isoforms exert functional differences in osteoblast
differentiation. J Biol Chem. 274:6972–6978. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Ann EJ, Kim HY, Choi YH, Kim MY, Mo JS,
Jung J, Yoon JH, Kim SM, Moon JS, Seo MS, Hong JA, Jang WG, Shore
P, Komori T, Koh JT and Park HS: Inhibition of Notch1 signaling by
Runx2 during osteoblast differentiation. J Bone Miner Res.
26:317–330. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Yoshida H, Hayashi S, Kunisada T, Ogawa M
and Nishikawa S, Okamura H, Sudo T, Shultz LD and Nishikawa S: The
murine mutation osteopetrosis is in the coding region of the
macrophage colony stimulating factor gene. Nature. 345:442–444.
1990. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Lagasse E and Weissman IL: Enforced
expression of Bcl-2 in monocytes rescues macrophages and partially
reverses osteopetrosis in op/op mice. Cell. 89:1021–1031. 1997.
View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Takahashi N, Udagawa N, Akatsu T, Tanaka
H, Isogai Y and Suda T: Deficiency of osteoclasts in osteopetrotic
mice is due to a defect in the local microenvironment provided by
osteoblastic cells. Endocrinology. 128:1792–1796. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Hattersley G, Owens J, Flanagan AM and
Chambers TJ: Macrophage colony stimulating factor (M-CSF) is
essential for osteoclast formation in vitro. Biochem Biophys Res
Commun. 177:526–531. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Tanaka S, Takahashi N, Udagawa N, Tamura
T, Akatsu T, Stanley ER, Kurokawa T and Suda T: Macrophage
colony-stimulating factor is indispensable for both proliferation
and differentiation of osteoclast progenitors. J Clin Invest.
91:257–263. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Yasuda H, Shima N, Nakagawa N, Yamaguchi
K, Kinosaki M, Mochizuki S, Tomoyasu A, Yano K, Goto M, Murakami A,
Tsuda E, Morinaga T, Higashio K, Udagawa N, Takahashi N and Suda T:
Osteoclast differentiation factor is a ligand for
osteoprotegerin/osteoclastogenesis-inhibitory factor and is
identical to TRANCE/RANKL. Proc Natl Acad Sci USA. 95:3597–3602.
1998. View Article : Google Scholar
|
|
60
|
Lacey DL, Timms E, Tan HL, Kelley MJ,
Dunstan CR, Burgess T, Elliott R, Colombero A, Elliott G, Scully S,
Hsu H, Sullivan J, Hawkins N, Davy E, Capparelli C, Eli A, Qian YX,
Kaufman S, Sarosi I, Shalhoub V, Senaldi G, Guo J, Delaney J and
Boyle WJ: Osteoprotegerin ligand is a cytokine that regulates
osteoclast differentiation and activation. Cell. 93:165–176. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Anderson DM, Maraskovsky E, Billingsley
WL, Dougall WC, Tometsko ME, Roux ER, Teepe MC, DuBose RF, Cosman D
and Galibert L: A homologue of the TNF receptor and its ligand
enhance T-cell growth and dendritic-cell function. Nature.
390:175–179. 1997. View
Article : Google Scholar : PubMed/NCBI
|
