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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2013 Volume 31 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Plasminogen activator inhibitor-1 in kidney pathology (Review)

Sylwia Małgorzewicz, Ewa Skrzypczak-Jankun, Jerzy Jankun
Pages: 503-510
Published online on: 10 January 2013

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Review

Redox regulation of tumor suppressor PTEN in cancer and aging (Review)

Yasuko Kitagishi, Satoru Matsuda
Pages: 511-515
Published online on: 10 January 2013

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Article Open Access

Non-conventional apoptotic response to ionising radiation mediated by N-methyl D-aspartate receptors in immature neuronal cells

Nada Samari, Louis De Saint-Georges, Giuseppe Pani, Sarah Baatout, Luc Leyns, Mohammed Abderrafi Benotmane
Pages: 516-524
Published online on: 15 January 2013

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Article

Newcastle disease virus Malaysian strain AF2240 induces apoptosis in MCF-7 human breast carcinoma cells at an early stage of the virus life cycle

Mohamed Ghrici, Mohamed El Zowalaty, Abdul Rahman Omar, Aini Ideris
Pages: 525-532
Published online on: 15 January 2013

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Article

Clinical relevance of plasma miR-106b levels in patients with chronic obstructive pulmonary disease

Seiko Soeda, Junko H. Ohyashiki, Kazushige Ohtsuki, Tomohiro Umezu, Yasuhiro Setoguchi, Kazuma Ohyashiki
Pages: 533-539
Published online on: 21 January 2013

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Article

p53 protein subcellular localization and apoptosis in rodent corneal epithelium cell culture following ultraviolet irradiation

Yevgeny Tendler, Russell Pokroy, Alex Panshin, Gary Weisinger
Pages: 540-546
Published online on: 16 January 2013

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Article

Analysis of differentially expressed genes and microRNAs in alcoholic liver disease

Ying Liu, Shao-Hua Chen, Xi Jin, You-Ming Li
Pages: 547-554
Published online on: 15 January 2013

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Article

Toll-like receptor 2 in promoting angiogenesis after acute ischemic injury

Yifei Xu, Ying Zhou, Haiyan Lin, Haiyang Hu, Yuxing Wang, Geng Xu
Pages: 555-560
Published online on: 11 January 2013

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Article

Involvement of N-cadherin in the protective effect of glial cell line-derived neurotrophic factor on dopaminergic neuron damage

Tao Zuo, Jane Yuxia Qin, Jing Chen, Zixiao Shi, Meiying Liu, Xiuxian Gao, Dianshuai Gao
Pages: 561-568
Published online on: 03 January 2013

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Article

The role of FoxO4 in the relationship between alcohol-induced intestinal barrier dysfunction and liver injury

Bing Chang, Lixuan Sang, Ying Wang, Jing Tong, Bingyuan Wang
Pages: 569-576
Published online on: 04 January 2013

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Article

Hypercholesterolemia accelerates amyloid β-induced cognitive deficits

Sun Haeng Park, Ji Hyun Kim, Kyung Ha Choi, Young Jung Jang, Sun Sik Bae, Byung Tae Choi, Hwa Kyoung Shin
Pages: 577-582
Published online on: 08 January 2013

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Article

The Wnt5a/Ror2 pathway is associated with determination of the differentiation fate of bone marrow mesenchymal stem cells in vascular calcification

Huaping Xin, Fang Xin, Shaoqiong Zhou, Siming Guan
Pages: 583-588
Published online on: 15 January 2013

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Article

Decreased cardiac mitochondrial tetrahydrobiopterin in a rat model of pressure overload

Shunichi Shimizu, Masaaki Ishibashi, Sumito Kumagai, Teruaki Wajima, Toshihito Hiroi, Tatsuya Kurihara, Masakazu Ishii, Yuji Kiuchi
Pages: 589-596
Published online on: 10 January 2013

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Article

Hydrogen-rich saline attenuates vascular smooth muscle cell proliferation and neointimal hyperplasia by inhibiting reactive oxygen species production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways

Yali Chen, Jinyao Jiang, Huibing Miao, Xingjuan Chen, Xuejun Sun, Yongjun Li
Pages: 597-606
Published online on: 22 January 2013

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Article

Role of glucagon-like peptide-1 in the pathogenesis of experimental irritable bowel syndrome rat models

Yan Chen, Zhengyang Li, Yan Yang, Lin Lin, Hongjie Zhang
Pages: 607-613
Published online on: 22 January 2013

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Article

Osteogenic potential of bone marrow stromal cells derived from streptozotocin-induced diabetic rats

Yan-Fang Zhao, De-Liang Zeng, Lun-Guo Xia, Song-Mei Zhang, Lian-Yi Xu, Xin-Quan Jiang, Fu-Qiang Zhang
Pages: 614-620
Published online on: 03 January 2013

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Article

Resveratrol inhibits human nasopharyngeal carcinoma cell growth via blocking pAkt/p70S6K signaling pathways

Meihong Zhang, Xin Zhou, Keyuan Zhou
Pages: 621-627
Published online on: 10 January 2013

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Article

Autophagy and apoptosis in tubular cells following unilateral ureteral obstruction are associated with mitochondrial oxidative stress

Yanfang Xu, Shiwei Ruan, Xiaonan Wu, Hong Chen, Ke Zheng, Binbin Fu
Pages: 628-636
Published online on: 08 January 2013

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Article

Aquaporin 1 plays an important role in myocardial edema caused by cardiopulmonary bypass surgery in goat

Yumei Yan, Jianbin Huang, Fangbao Ding, Ju Mei, Jiaquan Zhu, Hao Liu, Kun Sun
Pages: 637-643
Published online on: 03 January 2013

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Article

Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibition of the p38 MAPK pathway in H9c2 cells

Runmin Guo, Jiancong Lin, Wenming Xu, Ning Shen, Liqiu Mo, Changran Zhang, Jianqiang Feng
Pages: 644-650
Published online on: 15 January 2013

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Article

Lentiviral-mediated RNA interference of lipoprotein-associated phospholipase A2 ameliorates inflammation and atherosclerosis in apolipoprotein E-deficient mice

Hui Zhang, Jinying Zhang, Deliang Shen, Li Zhang, Fei He, Yuhua Dang, Ling Li
Pages: 651-659
Published online on: 16 January 2013

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Article

Thrombin-induced TGF-β1 pathway: A cause of communicating hydrocephalus post subarachnoid hemorrhage

Tong Li, Peng Zhang, Bin Yuan, Dongliang Zhao, Yueqin Chen, Xinzhong Zhang
Pages: 660-666
Published online on: 22 January 2013

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Article

Serum from hepatectomized rats induces the differentiation of adipose tissue mesenchymal stem cells into hepatocyte-like cells and upregulates the expression of hepatocyte growth factor and interleukin-6 in vitro

Jiangyang Sun, Yufeng Yuan, Haiquan Qin, Chengcheng Ying, Weijun Liu, Jin Zhang, Yueming He, Zhisu Liu
Pages: 667-675
Published online on: 23 January 2013

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Article

Global transcriptional profiling of the postmortem brain of a patient with G114V genetic Creutzfeldt-Jakob disease

Chan Tian, Di Liu, Chen Chen, Yin Xu, Han-Shi Gong, Cao Chen, Qi Shi, Bao-Yun Zhang, Jun Han, Xiao-Ping Dong
Pages: 676-688
Published online on: 10 January 2013

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Article

The bone tissue compatibility of a new Ti35Nb2Ta3Zr alloy with a low Young's modulus

Yongyuan Guo, Desheng Chen, Mengqi Cheng, Weijie Lu, Liqiang Wang, Xianlong Zhang
Pages: 689-697
Published online on: 16 January 2013

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Article

Effect of radiation on the Notch signaling pathway in osteoblasts

Bing Yang, Quan Tang, Janine Post, Hui Zhou, Xiao-Bin Huang, Xiao-Dong Zhang, Qin Wang, Yuan-Ming Sun, Fei-Yue Fan
Pages: 698-706
Published online on: 22 January 2013

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Article

Apolipoprotein A-IV as a novel gene associated with polycystic ovary syndrome

Yong-Soo Kim, Bon-Hee Gu, Bum-Chae Choi, Myung-Sun Kim, Sangjin Song, Ji-Hyun Yun, Mi Kyung Chung, Cheol-Hee Choi, Kwang-Hyun Baek
Pages: 707-716
Published online on: 17 January 2013

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Article

Correlation between erythropoietin receptor(s) and estrogen and progesterone receptor expression in different breast cancer cell lines

Nina Trošt, Neli Hevir, Tea Lanišnik Rižner, Nataša Debeljak
Pages: 717-725
Published online on: 08 January 2013

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Article

Anticancer effects of O-desmethylangolensin are mediated through cell cycle arrest at the G2/M phase and mitochondrial-dependent apoptosis in Hep3B human hepatocellular carcinoma cells

Eun Jeong Choi, Jae-In Lee, Gun-Hee Kim
Pages: 726-730
Published online on: 08 January 2013

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Article

Identification and analysis of expressed genes using a cDNA library from rat thymus during regeneration following cyclophosphamide-induced T cell depletion

Tae-Deuk Yoon, Hee-Woo Lee, Yong-Sik Kim, Hee Jung Choi, Jeon-Ok Moon, Sik Yoon
Pages: 731-739
Published online on: 10 January 2013

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Article Open Access

Nitric oxide activates intradomain disulfide bond formation in the kinase loop of Akt1/PKBα after burn injury

X.-M. Lu, R. G. Tompkins, A. J. Fischman
Pages: 740-750
Published online on: 11 January 2013

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Article

Generation of Mycobacterium tuberculosis-specific recombinant antigens and evaluation of the clinical value of antibody detection for serological diagnosis of pulmonary tuberculosis

Xia Zhang, Zhonglan Su, Xiangrong Zhang, Chunmei Hu, Jun Yu, Qian Gao, Hongwei Wang
Pages: 751-757
Published online on: 22 January 2013

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Journal Cover
June-2026 Volume 57 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Gilteritinib overcomes second‑generation TKIs resistance in ALK‑rearranged non‑small‑cell lung cancer by inhibiting PD‑L1 and CD8 co‑expression

Hang Guo, Yaoji Li, Chengyan Jin, Xiao Qi, Jincheng Wang, Baofeng Li, Chunguang Wang
Article Number: 168
Published online on: 28 April 2026

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Retraction Open Access

[Retracted] Metformin‑induced activation of AMPK inhibits the proliferation and migration of human aortic smooth muscle cells through upregulation of p53 and IFI16

Biao Hao, Yan Xiao, Fang Song, Xiangshu Long, Jing Huang, Maobo Tian, Shiyan Deng, Qiang Wu
Article Number: 167
Published online on: 22 April 2026

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Review Open Access

Dysregulation of the DNA repair‑immune axis: Targeted therapeutic strategies for autoimmune diseases (Review)

Ke Wan, Miao Wang, Qingqing Xia, Hui Fang, Ying Chen, Tongsheng Zhou, Xue Yang, Lu Wang, Jianwen Ye, Han Shu, Xiao-Feng Li, Jun Li
Article Number: 166
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Puerarin attenuates glucocorticoid‑induced apoptosis of hFOB1.19 cells through the JNK‑ and Akt‑mediated mitochondrial apoptotic pathways

Dongdong Yu, Shuai Mu, Danyang Zhao, Guangbin Wang, Zhiguang Chen, Hongfei Ren, Qin Fu
Article Number: 165
Published online on: 20 April 2026

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Review Open Access

High‑altitude polycythemia: Unveiling the molecular landscape beyond erythropoietin (Review)

Haiyan Li, Hongjuan Zhang, Hujun Zhang, Yujie Li, Yigang He, Jia Luan
Article Number: 164
Published online on: 17 April 2026

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Review

Mechanistic roles of interleukin‑18 in colonic immunity across infection, inflammatory bowel disease, and colorectal cancer (Review)

Jingwen Zhang, Lili Bao, Xia Li, Jiaxi Li, Jiaxian Cui, Lu Qiao, Xiaoxia He, Mingyu Zhang, Jingkun Lu, Xuan Zhang, Jing Dong, Gesi Tao, Tuya Bai, Yun Peng Tian, Pengwei Zhao, Ya Tuo
Article Number: 163
Published online on: 17 April 2026

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Article Open Access

IDH2 lactylation regulates mitochondrial dysfunction injury induced by myocardial ischemia‑reperfusion via the AMPK signaling pathway

Changsen Wang, Siman Shen, Suyun Chen, Jinda Lin, Simeng Li, Jianning Chen, Shuyun Cai, Xiaodong Yuan, Ziqiang Yang, Kun Ding, Li Xu, Liangqing Zhang
Article Number: 162
Published online on: 17 April 2026

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Review Open Access

Context‑dependent duality of the apelin/elabela‑APJ system in diabetes and its complications (Review)

Zhenyuan Han, Jiale Zhang, Min Shi, Juan Chen, Anni Li, Yuxuan Ye, Hong Zhang
Article Number: 161
Published online on: 17 April 2026

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Review Open Access

Glycolytic lactylation modulates cell death decisions in diabetic kidney disease: Metabolic‑epigenetic interplay between ferroptosis and autophagy in fibrotic remodeling (Review)

Taimin Zhang, Xizhe Zhang, Yaru Xie, Yue Liu, Siyu Xia, Xiaodie Yin, Tian Li, Libin Liao
Article Number: 160
Published online on: 16 April 2026

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Retraction Open Access

[Retracted] Quercetin promotes the apoptosis of fibroblast‑like synoviocytes in rheumatoid arthritis by upregulating lncRNA MALAT1

Fang Pan, Lihua Zhu, Haozhe Lv, Chunpeng Pei
Article Number: 159
Published online on: 15 April 2026

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Article Open Access

Triptolide exerts antiviral effects and alleviates influenza A‑induced pneumonia by inhibiting the overactivation of absent in melanoma 2 signaling in immune cells

Yeyang Chen, Hua Wu, Xiangjian Wu, Likun Che, Xiaoyan Fu, Ruihan Qi, Dan Jia, Minfang Li, Wei Xie, Wenxiang Zhu
Article Number: 158
Published online on: 15 April 2026

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Review Open Access

ETS‑1/ETS‑2 transcription factors in CVD (Review)

Shasha Yang, Jing Zhang, Ying Yang, Yunbo Lv, Jian Yang, Huibo Wang
Article Number: 157
Published online on: 15 April 2026

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Review Open Access

RNA‑binding proteins as epithelial transcriptome orchestrators in gastric cancer: Immune‑metabolic crosstalk and therapeutic vulnerability (Review)

Shuhui Liu, Zhiyuan Ma, Bei Ji, Jiaxing Zhu, Shun Yao, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 156
Published online on: 14 April 2026

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Retraction Open Access

[Retracted] Role of miR‑146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitro  

Lei Jin, Jian Zhao, Wensen Jing, Shiju Yan, Xin Wang, Chun Xiao, Baoan Ma
Article Number: 155
Published online on: 07 April 2026

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Review Open Access

A tale of dual role: HECT‑type E3 ubiquitin ligase mechanisms in liver diseases (Review)

Tongxi Li, Hao Chen, Peng Zhao, Chuanzheng Yin, Zifang Song
Article Number: 154
Published online on: 07 April 2026

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Correction Open Access

[Corrigendum] Macrophage‑derived foam cells impair endothelial barrier function by inducing endothelial‑mesenchymal transition via CCL‑4 

Ying Yang, Nian-Sang Luo, Ru Ying, Yong Xie, Jia-Yuan Chen, Xiao-Qiao Wang, Zhen-Jie Gu, Jing-Ting Mai, Wen-Hao Liu, Mao-Xiong Wu, Zhi-Teng Chen, Yong-Biao Fang, Hai-Feng Zhang, Zhi-Yi Zuo, Jing-Feng Wang, Yang-Xin Chen
Article Number: 153
Published online on: 03 April 2026

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Review Open Access

Macrophage metabolism reprogramming in sepsis: Pathogenesis and therapeutic implications (Review)

Tong Zhao, Wenzhe Zhang, Zixuan Ren, Xiujing Feng
Article Number: 152
Published online on: 03 April 2026

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Article Open Access

Astragaloside IV targets TUBB4B to inhibit proliferation and promote apoptosis of pituitary tumor cells via the STMN1/ERK pathway

Jiale Li, Yufei Qu, Wenge Zhang, Zexu Yang, Yangdong Zeng, Jisheng Xu, Kuncen Xie, Qi Liu
Article Number: 151
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation

Keng Wu, Wenming Xu, Qiong You, Runmin Guo, Jianqiang Feng, Changran Zhang, Wen Wu
Article Number: 150
Published online on: 01 April 2026

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Review Open Access

Animal models accurately representing acute liver failure (Review)

Sang Luo, Fang Wu, Yiran Jin, Xiaofen Huang, Dan Liu, Bingren Tian
Article Number: 149
Published online on: 01 April 2026

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Correction Open Access

[Corrigendum] Influence of aspirin on the CX3CL1/CX3CR1 signaling pathway in acute pulmonary embolism 

Zhirong Zhang, Weiji Yang, Rongbiao Ying, Ying Shi, Huifang Jiang, Danli Cai, Jing Kuang, Ruhui Yang, Lingcong Wang
Article Number: 148
Published online on: 31 March 2026

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Review Open Access

Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review)

Jing Mao, Mandi Luo, Lei Ruan, Cuntai Zhang
Article Number: 147
Published online on: 31 March 2026

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Review Open Access

Role of aging‑related cytokines in neurodegenerative disease (Review)

Xinke Dai, Xinran Rao, Yuandi Wang, Weijiang Zhao
Article Number: 146
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] DTX3L is upregulated in glioma and is associated with glioma progression

Peng Xu, Xuelei Tao, Chengjin Zhao, Qingfeng Huang, Hao Chang, Na Ban, Yuanqi Bei, Xiaojie Xia, Chaoyan Shen, Kun Wang, Li Xu, Peizhang Wu, Jianbing Ren, Donglin Wang
Article Number: 145
Published online on: 30 March 2026

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Review Open Access

Role of itaconate in intestinal disease (Review)

Xin Li, Qian Liu, Jiajia Li, Li Zhang, Shun Yao, Lulu Tang, Bingqi Yang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 144
Published online on: 27 March 2026

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Review Open Access

Unveiling lactylation: A novel frontier in the pathogenesis of diabetic nephropathy (Review)

Yuanyuan Xiao, Niansong Wang, Dingkun Gui, Youhua Xu
Article Number: 143
Published online on: 27 March 2026

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Review Open Access

Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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Article Open Access

circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
Published online on: 26 March 2026

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Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Article Open Access

Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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July-2026 Volume 58 Issue 1

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Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Dapagliflozin attenuates ferroptosis in diabetic nephropathy through activation of the Nrf2/HO‑1 signaling pathway

Hanshuang Liu, Xiaoxiao Zhang, Yubing Cui, Shengxi Xiong, Linjuan Huang, Min Li, Chen Shao, Xiaolei Hu
Article Number: 171
Published online on: 30 April 2026

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Ligustroflavone protects against acute kidney injury by inhibiting ferroptosis via acting on GSK3β/NRF2 signaling

Jiayu Song, Long Wang, Yaru Wang, Jie Meng, Jingyi Sheng, Yongfeng Zhao, San Yan Xu, Juan Lei, Fangfang Cai, Yunwen Yang
Article Number: 170
Published online on: 30 April 2026

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Correction Open Access

[Corrigendum] Differential regulation of the biosynthesis of glucose transporters by the PI3‑K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla

Yoen Kyung Lee, Ji Eun Kim, So Hee Nam, Jun Seo Goo, Sun Il Cho, Young Hwan Choi, Chang Jun Bae, Ong Min Woo, Jung Sik Cho, Dae Youn Hwang
Article Number: 169
Published online on: 28 April 2026

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