|
1
|
Bednarek AK, Laflin KJ, Daniel RL, Liao Q,
Hawkins KA and Aldaz CM: WWOX, a novel WW domain-containing protein
mapping to human chromosome 16q23.3–24.1, a region frequently
affected in breast cancer. Cancer Res. 60:2140–2145.
2000.PubMed/NCBI
|
|
2
|
Ried K, Finnis M, Hobson L, et al: Common
chromosomal fragile site FRA16D sequence: identification of the FOR
gene spanning FRA16D and homozygous deletions and translocation
breakpoints in cancer cells. Hum Mol Genet. 9:1651–1663. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Del Mare S, Salah Z and Aqeilan RI: WWOX:
its genomics, partners, and functions. J Cell Biochem. 108:737–745.
2009.PubMed/NCBI
|
|
4
|
Macias MJ, Wiesner S and Sudol M: WW and
SH3 domains, two different scaffolds to recognize proline-rich
ligands. FEBS Lett. 513:30–37. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Nunez MI, Ludes-Meyers J and Aldaz CM:
WWOX protein expression in normal human tissues. J Mol Hist.
37:115–125. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Wang X, Chao L, Jin G, Ma G, Zang Y and
Sun J: Association between CpG island methylation of the WWOX gene
and its expression in breast cancers. Tumour Biol. 30:8–14. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Guo W, Wang G, Dong Y, Guo Y, Kuang G and
Dong Z: Decreased expression of WWOX in the development of
esophageal squamous cell carcinoma. Mol Carcinog. Dec 27–2011.(Epub
ahead of print).
|
|
8
|
Nakayama S, Semba S, Maeda N, Matsushita
M, Kuroda Y and Yokozaki H: Hypermethylation-mediated reduction of
WWOX expression in intraductal papillary mucinous neoplasms of the
pancreas. Br J Cancer. 100:1438–1443. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Dias EP, Pimenta FJ, Sarquis MS, et al:
Association between decreased WWOX protein expression and thyroid
cancer development. Thyroid. 17:1055–1059. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Yang J, Cogdell D, Yang D, et al: Deletion
of the WWOX gene and frequent loss of its protein expression in
human osteosarcoma. Cancer Lett. 291:31–38. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Fabbri M, Iliopoulos D, Trapasso F, et al:
WWOX gene restoration prevents lung cancer growth in vitro and in
vivo. Proc Natl Acad Sci USA. 102:15611–15616. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Iliopoulos D, Fabbri M, Druck T, Qin HR,
Han SY and Huebner K: Inhibition of breast cancer cell growth in
vitro and in vivo: effect of restoration of Wwox expression. Clin
Cancer Res. 13:268–274. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Aqeilan RI, Trapasso F, Hussain S, et al:
Targeted deletion of Wwox reveals a tumor-suppressor function. Proc
Natl Acad Sci USA. 104:3949–3954. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Aqeilan RI, Pekarsky Y, Herrero JJ, et al:
Functional association between Wwox tumor suppressor protein and
p73, a p53 homolog. Proc Natl Acad Sci USA. 101:4401–4406. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Hezova R, Ehrmann J and Kolar Z: WWOX, a
new potential tumor suppressor gene. Biomed Pap Med Fac Univ
Palacky Olomouc Czech Repub. 151:11–15. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Yang JL and Zhang W: WWOX tumor suppressor
gene. Histol Histopathol. 23:877–882. 2008.
|
|
17
|
Chang NS, Hsu LJ, Lin YS, Lai FJ and Sheu
HM: WW domain-containing oxidoreductase: a candidate tumor
suppressor. Trends Mol Med. 13:12–22. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Gomes CC, Diniz MG, Oliveira CS, Tavassoli
M, Odell EW, Gomez RS and De Marco L: Impact of WWOX alterations on
p73, ΔNp73, p53, cell proliferation and DNA ploidy in salivary
gland neoplasms. Oral Dis. 17:564–571. 2011.
|
|
19
|
Aqeilan RI, Kuroki T, Pekarsky Y, et al:
Loss of WWOX expression in gastric carcinoma. Clin Cancer Res.
10:3053–3058. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Alsop AE, Taylor K, Zhang J, Gabra H,
Paige AJ and Edwards PA: Homozygous deletions may be markers of
nearby heterozygous mutations: the complex deletion at FRA16D in
the HCT116 colon cancer cell line removes exons of WWOX. Genes
Chromosomes Cancer. 47:437–447. 2008. View Article : Google Scholar
|
|
21
|
Żelazowski MJ, Płuciennik E, Pasz-Walczak
G, Potemski P, Kordek R and Bednarek AK: WWOX expression in
colorectal cancer: a real-time quantitative RT-PCR study. Tumour
Biol. 32:551–560. 2011.PubMed/NCBI
|
|
22
|
Qin HR, Iliopoulos D, Semba S, et al: A
role for the WWOX gene in prostate cancer. Cancer Res.
66:6477–6480. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Ishii H and Furukawa Y: Alterations of
common chromosome fragile sites in hematopoietic malignancies. Int
J Hematol. 79:238–242. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Ishii H, Vecchione A, Furukawa Y, et al:
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic
malignancies. Mol Cancer Res. 1:940–947. 2003.PubMed/NCBI
|
|
25
|
Watanabe A, Hippo Y, Taniguchi H, et al:
An opposing view on WWOX protein function as a tumor suppressor.
Cancer Res. 63:8629–8633. 2003.PubMed/NCBI
|
|
26
|
Chang NS: A potential role of p53 and WOX1
in mitochondrial apoptosis (Review). Int J Mol Med. 9:19–24.
2002.PubMed/NCBI
|
|
27
|
Aqeilan RI, Donati V, Palamarchuk A, et
al: WW domain-containing proteins, WWOX and YAP, compete for
interaction with ErbB-4 and modulate its transcriptional function.
Cancer Res. 65:6764–6772. 2005. View Article : Google Scholar : PubMed/NCBI
|
