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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2013 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

High mobility group box 1 and kidney diseases (Review)

Ping Zhu, Li Xie, Hua-Sheng Ding, Quan Gong, Jian Yang, Lin Yang
Pages: 763-768
Published online on: 25 February 2013

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Article Open Access

Temporal differential effects of proinflammatory cytokines on osteoclastogenesis

Su-Jin Moon, Inhye E. Ahn, Hyerin Jung, Hyoju Yi, Juryun Kim, Youngkyun Kim, Seung‑Ki  Kwok, Kyung-Su Park, Jun‑Ki  Min, Sung-Hwan Park, Ho-Youn Kim, Ji Hyeon Ju
Pages: 769-777
Published online on: 05 February 2013

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Article

15-Deoxy-Δ12,14-prostaglandin J2 induces growth inhibition, cell cycle arrest and apoptosis in human endometrial cancer cell lines

Haili Li, Hisashi Narahara
Pages: 778-788
Published online on: 05 February 2013

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Article

Microarray analyses of peripheral whole blood cells from ulcerative colitis patients: Effects of leukocytapheresis

Teppei Kobayashi, Keiichi Mitsuyama, Hiroshi Yamasaki, Junya Masuda, Hidetoshi Takedatsu, Kotaro Kuwaki, Shinichiro Yoshioka, Koji Nagayama, Michio Sata
Pages: 789-796
Published online on: 06 February 2013

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Article

Expression profiles of miRNAs in polarized macrophages

Yingying Zhang, Mengying Zhang, Min Zhong, Qifeng Suo, Kun Lv
Pages: 797-802
Published online on: 30 January 2013

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Article

Arginase inhibition by piceatannol-3'-O-β-D-glucopyranoside improves endothelial dysfunction via activation of endothelial nitric oxide synthase in ApoE-null mice fed a high-cholesterol diet

Ainieng Woo, Woosung Shin, To Dao Cuong, Byungsun Min, Jeong Hyung Lee, Byung Hwa Jeon, Sungwoo Ryoo
Pages: 803-810
Published online on: 30 January 2013

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Article

Sphingosine-1-phosphate protects against bisphosphonate‑induced HUVEC cell death via regulation of c-Jun‑N‑terminal kinase signaling

You-Jin Lee, Jae-Kyo Jeong, Ju-Hee Lee, Yang-Gyu Park, Ji-Hong Moon, Jae-Won Seol, Christopher J. Jackson, Sang-Youel Park
Pages: 811-816
Published online on: 04 February 2013

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Article

Low-dose taurine upregulates taurine transporter expression in acute myocardial ischemia

Yue Zhang, Lin Yang, Yu-Jie Yang, Xiao-Yu Liu, Jian-Guo Jia, Ju-Ying Qian, Ke-Qiang Wang, Ji Zuo, Jun-Bo Ge
Pages: 817-824
Published online on: 01 February 2013

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Article

Rapamycin protects the mitochondria against oxidative stress and apoptosis in a rat model of Parkinson's disease

Jianhua Jiang, Juean Jiang, Yuanyi Zuo, Zhenlun Gu
Pages: 825-832
Published online on: 20 February 2013

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Article

Hydrodynamics-based delivery of an interleukin-1 receptor II fusion gene ameliorates rat autoimmune myocarditis by inhibiting IL-1 and Th17 cell polarization

He Chang, Yan Wang, Weiyin Wu, Gang Li, Haruo Hanawa, Jun Zou
Pages: 833-840
Published online on: 11 February 2013

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Article

Gua Lou Gui Zhi decoction exerts neuroprotective effects on post-stroke spasticity via the modulation of glutamate levels and AMPA receptor expression

Jia Huang, Jing Tao, Xiehua Xue, Shanli Yang, Ping Han, Zhicheng Lin, Wei Xu, Jiumao Lin, Jun Peng, Lidian Chen
Pages: 841-848
Published online on: 30 January 2013

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Article

p73 participates in WWOX-mediated apoptosis in leukemia cells Retraction in /10.3892/ijmm.2026.5925

Donghong Lin, Zhaolei Cui, Lingying Kong, Feng Cheng, Jianping Xu, Fenghua Lan
Pages: 849-854
Published online on: 26 February 2013

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Article

DEC1 is positively associated with the malignant phenotype of invasive breast cancers and negatively correlated with the expression of claudin-1

Yang Liu, Yuan Miao, Jian Wang, Xuyong Lin, Liang Wang, Hong-Tao Xu, En-Hua Wang
Pages: 855-860
Published online on: 19 February 2013

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Article

ACF7 regulates colonic permeability

Yong Liang, Chenzhang Shi, Jun Yang, Hongqi Chen, Yang Xia, Peng Zhang, Feng Wang, Huazhong Han, Huanlong Qin
Pages: 861-866
Published online on: 21 February 2013

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Article

Antiviral activity of Isatis indigotica root-derived clemastanin B against human and avian influenza A and B viruses in vitro

Zifeng Yang, Yutao Wang, Zhaoguang Zheng, Suishan Zhao, Jin Zhao, Qing Lin, Chuyuan Li, Quan Zhu, Nanshan Zhong
Pages: 867-873
Published online on: 07 February 2013

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Article

A crucial role for reactive oxygen species in macrophage colony-stimulating factor-induced RANK expression in osteoclastic differentiation

Atsuko Nakanishi, Mamiko Hie, Natsumi Iitsuka, Ikuyo Tsukamoto
Pages: 874-880
Published online on: 30 January 2013

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Article

Alleviation of asthma-related symptoms by a derivative of L-allo threonine

Jin-Chul Heo, Sang-Han Lee
Pages: 881-887
Published online on: 01 February 2013

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Article

Protective effects of gomisin A isolated from Schisandra chinensis against CCl4-induced hepatic and renal injury

In Sik Hwang, Jee Eun Kim, Yong Ju Lee, Moon Hwa Kwak, Young Hwan Choi, Byeong Cheol Kang, Jin Tae Hong, Dae Youn Hwang
Pages: 888-898
Published online on: 31 January 2013

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Article

Mutational and functional analysis of the BVES gene coding region in Chinese patients with non-syndromic tetralogy of Fallot

Min Wu, Ying Li, Xin He, Xiuqin Shao, Fan Yang, Ming Zhao, Chong Wu, Cuifang Zhang, Lei Zhou
Pages: 899-903
Published online on: 07 February 2013

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Article

mTOR inhibitor RAD001 (everolimus) induces apoptotic, not autophagic cell death, in human nasopharyngeal carcinoma cells

Yuchen Cai, Qing Xia, Quanguan Su, Rongzhen Luo, Yueli Sun, Yanxia Shi, Wenqi Jiang
Pages: 904-912
Published online on: 21 February 2013

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Article

Maintenance of high proliferation and multipotent potential of human hair follicle-derived mesenchymal stem cells by growth factors

Xueyan Zhang, Yimei Wang, Yunhe Gao, Xuejuan Liu, Tingting Bai, Meiying  Li, Lisha Li, Guanfan Chi, Hui Xu, Feilin Liu, Jin Yu Liu, Yulin Li
Pages: 913-921
Published online on: 06 February 2013

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Article

Benzo[a]pyrene induces oxidative stress and endothelial progenitor cell dysfunction via the activation of the NF-κB pathway

Kangting Ji, Cheng Xing, Fengchun Jiang, Xiaoyan Wang, Huihui Guo, Jinliang Nan, Lu Qian, Penglin Yang, Jiafeng Lin, Meide Li, Jinnong Li, Lianming Liao, Jifei Tang
Pages: 922-930
Published online on: 26 February 2013

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Article

Anti-inflammatory effects of total alkaloids from Rubus aleaefolius Poir. on non-alcoholic fatty liver disease through regulation of the NF-κB pathway Erratum in /ijmm/33/4/1048

Jinyan Zhao, Haiyin Zheng, Yan Liu, Jiumao Lin, Xiaoyong Zhong, Wei Xu, Zhenfeng Hong, Jun Peng
Pages: 931-937
Published online on: 20 February 2013

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Article

Nicotine favors osteoclastogenesis in human periodontal ligament cells co-cultured with CD4+ T cells by upregulating IL-1β

Li-Zheng Wu, Duo-Mo Duan, Ying-Feng Liu, Xin Ge, Zhi-Fei Zhou, Xiao-Jing Wang
Pages: 938-942
Published online on: 30 January 2013

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Article

Serum protein isoform profiles indicate the progression of hepatitis C virus-induced liver diseases

Kazushi Sugimoto, Katsuya Shiraki, Yoshiyuki Takei, Masaaki  Ito, Tsutomu Nobori, Hideaki Suzuki, Santha K. Dissanayaka, Kohji  Meno, Makoto Asashima, Kazuhiko Uchida
Pages: 943-950
Published online on: 04 February 2013

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Article

Piceatannol inhibits mast cell-mediated allergic inflammation

Yu-Jin Ko, Hui-Hun Kim, Eun-Jung Kim, Yoshinori Katakura, Won-Sup Lee, Gon-Sup Kim, Chung-Ho Ryu
Pages: 951-958
Published online on: 21 February 2013

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Article

Identification of immediate early gene X-1 as a cellular target gene of hcmv-mir-UL148D

Yue-Ping Wang, Ying Qi, Yu-Jing Huang, Man-Long Qi, Yan-Ping Ma, Rong He, Yao-Hua Ji, Zheng-Rong Sun, Qiang Ruan
Pages: 959-966
Published online on: 06 February 2013

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Article

Anticancer effects of sodium butyrate on hepatocellular carcinoma cells in vitro

Hong-Gang Wang, Xiao-Dan Huang, Peng Shen, Lu-Rong Li, Hui-Ting Xue, Guo-Zhong Ji
Pages: 967-974
Published online on: 22 February 2013

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Article

A novel method for the analysis of drug-resistant phenotypes of hepatitis B virus

Bo Qin, Tingting He, Zhijun Chen, Wenying Xu, Guoshao Pan, Chunyu Tu
Pages: 975-981
Published online on: 11 February 2013

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Article

EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin-induced murine model of asthma

In Sik Shin, Mee Young Lee, Woo Young Jeon, Na Ra Shin, Chang Seob Seo, Hyekyung Ha
Pages: 982-988
Published online on: 06 February 2013

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Article

Aberrant expression of circulating Th17, Th1 and Tc1 cells in patients with active and inactive ulcerative colitis

Zhaogang Dong, Lutao Du, Xiaofei Xu, Yongmei Yang, Haiyan Wang, Ailin Qu, Xun Qu, Chuanxin Wang
Pages: 989-997
Published online on: 26 February 2013

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Correction Open Access

[Corrigendum] Invariant NKT cells produce IL-17 through IL-23-dependent and -independent pathways with potential modulation of Th17 response in collagen-induced arthritis

Y. Yoshiga, D. Goto, S. Segawa, Y. Ohnishi, I. Matsumoto, S. Ito, A. Tsutsumi, M. Taniguchi, T. Sumida
Pages: 998-998
Published online on: 19 February 2013

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Journal Cover
August-2026 Volume 58 Issue 2

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Myokines in exercise‑mediated bone homeostasis: Molecular signaling mechanisms and therapeutic implications for bone disorders (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 231
Published online on: 24 June 2026

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Review Open Access

Neutrophil extracellular traps in thrombosis of hematologic malignancies: Underlying mechanisms and therapeutic opportunities (Review)

Kebing Lv, Zijie Ma, Qiuni Chen, Yang Su, Jingjing Ma, Chunling Wang, Liang Yu
Article Number: 230
Published online on: 23 June 2026

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Article Open Access

Recombinant myonectin ameliorates sepsis‑induced cardiomyopathy by alleviating mitochondrial dysfunction via the AdipoR1/AMPK pathway

Peipei Li, Rui Chen, Hanmo Zhang, Lihong Li, Huiling Luo, Beibei Du, Ping Yang
Article Number: 229
Published online on: 23 June 2026

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Review Open Access

MTA2: Decoding pathogenic mechanisms, clinical implications and therapeutic frontiers across disease landscapes (Review)

Hao Xie, Ling Chen, Jing Gou, Xuehong Long, Ya Yang, Hai Hu, Ping Wu, Qibing Yan, Yongkang Wu
Article Number: 228
Published online on: 22 June 2026

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Review Open Access

Mitochondria‑endoplasmic reticulum contact site nexus: Molecular integration, disease pathogenesis and therapeutic opportunities (Review)

Yi Liu, Xianda Che, Wei Wei, Chong Teng, Huimin Li
Article Number: 227
Published online on: 22 June 2026

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Review Open Access

Metabolic messengers from the gut to the joint: Toward precision management of osteoarthritis (Review)

Ruipu Zhang, Liang Zhang, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 226
Published online on: 22 June 2026

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Retraction Open Access

[Retracted] Protection of telomeres 1 protein levels are associated with telomere length in gastric cancer

Kiyomu Fujii, Tomonori Sasahira, Yukiko Moriwaka, Naohide Oue, Wataru Yasui, Hiroki Kuniyasu
Article Number: 225
Published online on: 22 June 2026

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Article Open Access

Molecular mechanism of hydromorphone preconditioning in cerebral ischemia/reperfusion‑induced inflammatory injury

Jing Yao, Zeqing Huang, Songze Li, Minghui Lun, Jianing Fan
Article Number: 224
Published online on: 18 June 2026

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Article Open Access

Oridonin ameliorates ulcerative colitis by regulating the PI3K/AKT/mTOR signaling pathway to activate autophagy

Zhongxing Miao, Baohong Liu, Xingzhi Zhou, Mengru Lu, Ni Jia, Huamin Zhang, Ying Qi, Xiaoyu Tan, Qinggao Zhang
Article Number: 223
Published online on: 18 June 2026

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Review Open Access

Arsenic exposure and skin cancer: Mechanisms, clinical evidence and public health implications (Review)

Dimitrios A. Andreikos, Michael Aschner, Dimitrios C. Ziogas, Aristidis Tsatsakis, Demetrios A. Spandidos
Article Number: 222
Published online on: 18 June 2026

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Review Open Access

Targeting glutathione metabolism for tumor radiosensitization (Review)

Haonan Xu, Meng Du, Xiaowen Liang, Xilin Xiao, Zhiyi Chen
Article Number: 221
Published online on: 16 June 2026

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Review Open Access

Effects of exercise‑derived extracellular vesicles: Epigenetic regulatory mechanisms and protective roles (Review)

Xinxin Zhang, Biao Zhang
Article Number: 220
Published online on: 15 June 2026

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Article Open Access

Moderate downregulation of NDUFA13 promotes cardiomyocytes proliferation and heart regeneration through the glycolysis/c‑Myc/Ccnd1 axis

Ying Gao, Ningjing Qian, Junyan Jin, Jiayi Liu, Bingqi Wang, Yaping Wang
Article Number: 219
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] (‑)‑Epigallocatechin‑3‑gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions

Yang Wu, Zhong-Yuan Xia, Bo Zhao, Yan Leng, Juan Dou, Qing-Tao Meng, Shao-Qing Lei, Zhi-Ze Chen, Jie Zhu
Article Number: 218
Published online on: 10 June 2026

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Article Open Access

Melatonin ameliorates circadian rhythm disruption induced erectile dysfunction by inhibiting oxidative stress mediated pyroptosis via Nrf2/HO‑1 axis

Qingtao Yang, Wei Li, Qi Yu, Jiang Shi, Lu Yang, Jun Qiao, Xi Wei, Changshi Gu, Fa Sun, Tao Li
Article Number: 217
Published online on: 09 June 2026

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Review Open Access

Spatial architecture of immunometabolism: Mitochondrial‑organelle interfaces in immune signaling (Review)

Yaping Wu, Hao Yu, Ling Xia, Li Yang, Yu Zhou, Qian Yu
Article Number: 216
Published online on: 08 June 2026

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Review Open Access

Urea cycle dysregulation and arginine pathways in the pathogenesis of NAFLD and NASH (Review)

Boying Zhu, Chaoyang Wang, Peng Liu, Zhifeng Qu, Ran Qi, Shengjiang Chen, Huanzhang Niu
Article Number: 215
Published online on: 08 June 2026

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Article Open Access

Withaferin A, a candidate drug for lupus nephritis, confers renal protection via Pon1‑mediated attenuation of oxidative stress

Miao Xue, Junshuai Feng, Xiaorong Mao
Article Number: 214
Published online on: 08 June 2026

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Retraction Open Access

[Retracted] Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome

Lang Li, Liang Dong, Dan Zhao, Fei Gao, Jie Yan
Article Number: 213
Published online on: 08 June 2026

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Review Open Access

Plant‑derived natural products alleviate dexamethasone‑induced skeletal muscle atrophy by modulating FoxO (Review)

Wei Dai, Jiabin Wu, Xiaotong Ma, Mingyu Wu, Ke Li, Haoyang Gao, Wenhong Wang, Weihua Xiao
Article Number: 212
Published online on: 05 June 2026

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Review Open Access

Functional hydrogels in cardiovascular therapy: Design, applications and clinical challenges (Review)

Zheming Yang, Jiayin Li, Lingxiao Zhao, Dali Zhang, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 211
Published online on: 04 June 2026

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Review Open Access

Experimental rodent models of cardiorenal syndrome types 3 and 4: Insights and clinical relevance (Review)

Stefanny M. Figueroa, Siyi Huang, Javier Reyes‑Osorio, Jean-Jacques Boffa, Cristián A. Amador, Christos E. Chadjichristos, Louis Boutin
Article Number: 210
Published online on: 04 June 2026

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Expression of Concern Open Access

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes

Zhanli Yang, Chuntao Yang, Liangcan Xiao, Xinxue Liao, Aiping Lan, Xiuyu Wang, Ruixian Guo, Peixi Chen, Chengheng Hu, Jianqiang Feng
Article Number: 209
Published online on: 03 June 2026

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Article Open Access

Microbiota‑derived indole‑3‑propionic acid reprograms bone marrow stem cell fate via PPARγ suppression to rescue osteoporosis

Jinwu Bai, Ruideng Wang, Jixing Fan, Shilong Su, Gao Si, Qinyong You, Ao Sun, Daole Hu, Shan Gao, Yang Lv, Fang Zhou
Article Number: 208
Published online on: 03 June 2026

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Article Open Access

Lactate regulates osteoclastogenesis via H3k18la in osteoarthritis

Zhibo Fan, Qiyue Fu, Tao Sun, Yutong Zhong, Yuefan Ma, Jingwei Jian, Shuosheng Yuan, Shenghong Li, Xiaomei Xu
Article Number: 207
Published online on: 02 June 2026

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Retraction Open Access

[Retracted] miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancert

Xiaoxu Gao, Yan Cai, Ruifang An
Article Number: 206
Published online on: 02 June 2026

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Review

Multi‑scale experimental models for the study of angiogenesis (Review)

Qin Yu, Jiarui Hu, Shuangshuang Yuan, Jiexia Gan, Mao Luo, Jianbo Wu, Liqun Wang
Article Number: 205
Published online on: 28 May 2026

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Review Open Access

Targeting lactylation in hepatocellular carcinoma: Mechanistic insights and therapeutic opportunities (Review)

Lianting Chen, Feiqiong Gao, Qianru Mei, Yujie Li, Qun Cai, Xudong Feng
Article Number: 204
Published online on: 28 May 2026

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Oxygen‑sensing histone demethylase KDM6A modulates chondrocyte‑to‑osteoblast transdifferentiation by activating the Wnt/β‑catenin pathway

Yi Rong, Hao Yu, Heng Yin, Shaoshuo Li, Jianwei Wang, Zhongyuan Shen, Xinxin Ding, Fanchen Bu, Tianyi Dai, Gean Wu, Zhen Hua
Article Number: 203
Published online on: 28 May 2026

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September-2026 Volume 58 Issue 3

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Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

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Cepharanthine inhibits tick‑borne encephalitis virus infection through modulation of the stress and inflammation response

Wan-Da Tang, Lan-Juan Zhao
Article Number: 261
Published online on: 16 July 2026

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circCACNA1D drives pulmonary fibrosis by regulating pyruvate kinase M2 dimer‑tetramer switching

Yujie Wang, Xiaoting Li, Meirong Wang, Nailiang Zhai, Mengqi Jiang, Bo Liu, Changjun Lv, Songzi Zhang, Xiaodong Song, Jinjin Zhang
Article Number: 260
Published online on: 15 July 2026

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Recent progress and therapeutic strategies in the treatment of cervical neuroendocrine neoplasms (Review)

Yanpeng Tian, Yu Zhang, Liling Wang, Zhongkang Li, Xiaotong Xu, Shouze Liu, Shenyu Yang, Xiangyang Ren, Menghan Xu, Xingzi Chang, Xianghua Huang, Qian Zhao, Ruixia Guo
Article Number: 259
Published online on: 15 July 2026

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Neurofibromin in bone disease: Mechanisms and therapeutic implications (Review)

Shuhong Zhang, Ge Yang
Article Number: 258
Published online on: 14 July 2026

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Exercise‑induced exosomal noncoding RNAs: Molecular signaling cascades in bone remodeling and translational applications in sports‑related bone injuries (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 257
Published online on: 14 July 2026

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Targeting alveolar type II cell dysfunction in idiopathic pulmonary fibrosis: Molecular mechanisms and emerging therapeutic strategies (Review)

Tianhao Xie, Kang Hu, Shu Pan, Xin Tong, Haitong Huang, Hao Ding, Jun Zhao
Article Number: 256
Published online on: 13 July 2026

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Tubular PFKFB3 drives diabetic kidney fibrosis via lactate‑dependent H4K12 lactylation and HIPK2 transactivation

Mingkun Xu, Linhang Fu, Yulong Zhang, Xiuli Guo, Han Wu, Sijing Gao, Fei Xiao, Li Xu
Article Number: 255
Published online on: 13 July 2026

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[Retracted] p73 participates in WWOX-mediated apoptosis in leukemia cells

Donghong Lin, Zhaolei Cui, Lingying Kong, Feng Cheng, Jianping Xu, Fenghua Lan
Article Number: 254
Published online on: 13 July 2026

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Role of hyperthermia in overcoming HPV‑mediated MHC‑Ⅰ downregulation and promoting immune surveillance

Hanyu Wang, Hongxin Lang, Yaoxing Guo, Te Sun, Yuansong Bai, Tao Zhang, Rui-Qun Qi
Article Number: 253
Published online on: 10 July 2026

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Endocrine‑metabolic imbalance drives osteoarthritis: From whole‑joint pathobiology to precision therapy (Review)

Ruhui Yang, Haimin Zeng, Qi Xiao, Yining Xie, Yi Long, Xiang Chen
Article Number: 252
Published online on: 09 July 2026

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Expression of Concern Open Access

[Expression of Concern] Roles and mechanisms of action of HNF‑4α in the hepatic differentiation of WB‑F344 cells

Yumeng Shi, Dehua Zhou, Bingyi Wang, Deren Zhou, Baomin Shi
Article Number: 251
Published online on: 08 July 2026

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Phenylalanine exacerbates psoriasiform inflammation through NF‑κB‑mediated dendritic cell activation and Th17 polarization

Yaohan Xu, Jing Pan, Jie Chen, Yutao Zhu, Miaolian Cai, Zeyu Ma, Siji Chen, Tianze Yu, Yushu Wei, Jingying Pan, Kunliang Luo, Yinjing Song, Stijn Van Der Veen, Hao Cheng
Article Number: 250
Published online on: 08 July 2026

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Protective effects of Astragaloside IV on various liver diseases: From chemistry to herbal medicines (Review)

Jialu Shi, Xiaoyu Zhou, Jiabin Wu, Liru Zeng, Xia Wang, Wei Li, Xiao Huang, Xiaoyu Deng, Wenhong Wang
Article Number: 249
Published online on: 07 July 2026

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GRP78 dysregulation: A proposed molecular mechanism linking the tumor microenvironment to sepsis susceptibility in patients with cancer (Review)

Hang Ruan, Meipeng Zhu, Shi-Yan Liu, Li-Juan Zou, Shu-Sheng Li
Article Number: 248
Published online on: 07 July 2026

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FGFR1 signaling in rheumatoid arthritis: Mechanisms of bone destruction and therapeutic targeting (Review)

Changzhong Qian, Zhenyu Zhang, Xian Wu, Huibo Ti, Junjie Wu, Zhengdong Yuan, Xia Li, Feng-Lai Yuan
Article Number: 247
Published online on: 06 July 2026

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Retraction Open Access

[Retracted] β‑catenin signaling induces the osteoblastogenic differentiation of human pre‑osteoblastic and bone marrow stromal cells mainly through the upregulation of osterix expression

Bo Liu, Song Wu, Lihua Han, Chaoyue Zhang
Article Number: 246
Published online on: 06 July 2026

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Single‑cell atlas reveals a Wilms' tumor 1‑mediated axis driving granulosa cell senescence in human ovarian aging

Yanfang Du, Congyu Zhou, Yanpeng Tian, Zhongkang Li, Xianghua Huang
Article Number: 245
Published online on: 03 July 2026

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TRPV1‑mediated central sensitisation: Core mechanisms of migraine chronification and novel targeted therapeutic strategies (Review)

Mingxia Zhang, Yuting Pu, Yujie Zhang, Jia Hu, Shuangyang Li, Hongmei Tang, Bangjiang Fang, Xue Bai
Article Number: 244
Published online on: 02 July 2026

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Correction Open Access

[Corrigendum] Arginine ADP‑ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway

Lian Yang, Ming Xiao, Xian Li, Yi Tang, Ya-Lan Wang
Article Number: 243
Published online on: 02 July 2026

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Research progress on the chemical and pharmacological effects of Semen Strychni (Review)

Jingxin Mao, Xin Du, Dan Zeng, Xin Luo, Yan Li
Article Number: 242
Published online on: 02 July 2026

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FLI1 enhances the malignant phenotype of glioma cells and exerts immunomodulatory effects through feedback crosstalk with exonic circRNA FECR1 and interferon‑induced ISG15

Xue Wen, Xiaoyi Gu, Xu Yan, Naifei Chen, Lei Zhou, Hui Li, Andrew R. Hoffman, Wei Li, Ji-Fan Hu, Jiuwei Cui
Article Number: 241
Published online on: 01 July 2026

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Role of ZEB1 in angiogenesis and therapeutic potential (Review)

Ruoxin Ren, Chunxiao Yan, Yao Xiang, Lin Jin, Fang Cheng, Lijun Zhang
Article Number: 240
Published online on: 01 July 2026

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Endothelial dysfunction: A central mechanism linking autosomal dominant polycystic kidney disease and intracranial aneurysms (Review)

Xiaohong Xu, Ruyi Xu, Liexiang Zhang
Article Number: 239
Published online on: 01 July 2026

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Correction Open Access

[Corrigendum] Effect of SDF‑1/CXCR4 axis on the migration of transplanted bone mesenchymal stem cells mobilized by erythropoietin toward lesion sites following spinal cord injury

Jun Li, Weichun Guo, Min Xiong, Heng Han, Jie Chen, Dan Mao, Bing Tang, Hualong Yu, Yun Zeng
Article Number: 238
Published online on: 01 July 2026

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Exercise and fluoxetine in Alzheimer's disease: Molecular mechanisms of synergistic and antagonistic effects (Review)

Mei Wu, Yan Li
Article Number: 237
Published online on: 30 June 2026

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Oral‑gut axis in systemic disease: A barrier‑metabolism‑immunity three‑dimensional regulatory model (Review)

Qing Li, Mingrong Cheng, Weiwei Li, Xiaoyue Wang, Xiaoqing Liu, Yujie Yan
Article Number: 236
Published online on: 30 June 2026

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ABCG2 transporter: Structural and functional associations with gout (Review)

Muhammad Arslan Asif, Zeshan Zulfiqar, Bahar E. Mustafa, Usman Nazir, Jiamen Sun, Zhichang Wang, Yalei Cui, Sun Hao, Liu Boshuai, Yinghua Shi
Article Number: 235
Published online on: 30 June 2026

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Neuropilin‑1: Emerging roles in nerve‑vessel‑bone coupling during fracture repair (Review)

Keyue Zhang, Tong Li, Huan Liu, Huibo Ti, Zhenyu Zhang, Zhengdong Yuan, Junjie Wu, Xielin Yan, Zixin Luo, Haiting Hu, Xingchen Yao, Shuwen Shi, Xian Wu, Feng-Lai Yuan, Xiao Chen
Article Number: 234
Published online on: 30 June 2026

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Correction Open Access

[Corrigendum] Crocin exerts anti‑inflammatory and anti‑catabolic effects on rat intervertebral discs by suppressing the activation of JNK

Kang Li, Yan Li, Zhenjiang Ma, Jie Zhao
Article Number: 233
Published online on: 29 June 2026

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Skeletal muscle‑derived extracellular vesicles in multi‑organ degenerative disease: Mechanisms and therapeutic delivery perspectives (Review)

Xianji Wei, Chengyan Guo, Wei Zhang, Guanyi Wang, Wenjing Li, Binghong Gao, Bo Gao, Lingli Zhang
Article Number: 232
Published online on: 26 June 2026

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