|
1
|
Rastaldi MP: Epithelial-mesenchymal
transition and its implications for the development of renal
tubulointerstitial fibrosis. J Nephrol. 19:407–412. 2006.PubMed/NCBI
|
|
2
|
Li MX and Liu BC: Epithelial to
mesenchymal transition in the progression of tubulointerstitial
fibrosis. Chinese Med J. 120:1925–1930. 2007.PubMed/NCBI
|
|
3
|
Liu Y: Cellular and molecular mechanisms
of renal fibrosis. Nat Rev. 7:684–696. 2011.PubMed/NCBI
|
|
4
|
Blanco D, Vicent S, Elizegi E, Pino I,
Fraga MF, Esteller M, Saffiotti U, Lecanda F and Montuenga LM:
Altered expression of adhesion molecules and epithelial-mesenchymal
transition in silica-induced rat lung carcinogenesis. Lab Invest.
84:999–1012. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Ozdamar B, Bose R, Barrios-Rodiles M, Wang
HR, Zhang Y and Wrana JL: Regulation of the polarity protein Par6
by TGFbeta receptors controls epithelial cell plasticity. Science.
307:1603–1609. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Kolosova I, Nethery D and Kern JA: Role of
Smad2/3 and p38 MAP kinase in TGF-beta1-induced
epithelial-mesenchymal transition of pulmonary epithelial cells. J
Cell Physiol. 226:1248–1254. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Lampropoulos P, Zizi-Sermpetzoglou A,
Rizos S, Kostakis A, Nikiteas N and Papavassiliou AG: TGF-beta
signalling in colon carcinogenesis. Cancer Lett. 314:1–7. 2011.
View Article : Google Scholar
|
|
8
|
Lv ZM, Wang Q, Wan Q, Lin JG, Hu MS, Liu
YX and Wang R: The role of the p38 MAPK signaling pathway in high
glucose-induced epithelial-mesenchymal transition of cultured human
renal tubular epithelial cells. PloS One. 6:e228062011. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Matsuzaki K: Smad phosphoisoform signaling
specificity: the right place at the right time. Carcinogenesis.
32:1578–1588. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Schneider D and Janshoff A: Inhibition of
actin dynamics during epithelial-to-mesenchymal transition. Biochem
Biophys Res Commun. 419:221–225. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Tian YC, Fraser D, Attisano L and Phillips
AO: TGF-beta1-mediated alterations of renal proximal tubular
epithelial cell phenotype. Am J Physiol. 285:F130–F142.
2003.PubMed/NCBI
|
|
12
|
Zhang H, Liu X, Liu Y, Yi B and Yu X:
Epithelial-mesenchymal transition of rat peritoneal mesothelial
cells via Rhoa/Rock pathway. In Vitro Cell Dev Biol. 47:165–172.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Zhang H, Liu FY and Liu YH: Effect of
TGF-beta1 stimulation on the smad signal transduction pathway of
human peritoneal mesothelial cells. Zhong Nan Da Xue Xue Bao Yi Xue
Ban. 29:142–147. 2004.(In Chinese).
|
|
14
|
Ryan MJ, Johnson G, Kirk J, Fuerstenberg
SM, Zager RA and Torok-Storb B: HK-2: an immortalized proximal
tubule epithelial cell line from normal adult human kidney. Kidney
Int. 45:48–57. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Black D, Lyman S, Qian T, Lemasters JJ,
Rippe RA, Nitta T, Kim JS and Behrns KE: Transforming growth factor
beta mediates hepatocyte apoptosis through Smad3 generation of
reactive oxygen species. Biochimie. 89:1464–1473. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Sun L, Xiao L, Nie J, Liu FY, Ling GH, Zhu
XJ, Tang WB, Chen WC, Xia YC, Zhan M, Ma MM, Peng YM, Liu H, Liu YH
and Kanwar YS: p66Shc mediates high-glucose and angiotensin
II-induced oxidative stress renal tubular injury via
mitochondrial-dependent apoptotic pathway. Am J Physiol.
299:F1014–F1025. 2010.PubMed/NCBI
|
|
17
|
Ronaldson PT, Demarco KM,
Sanchez-Covarrubias L, Solinsky CM and Davis TP: Transforming
growth factor-beta signaling alters substrate permeability and
tight junction protein expression at the blood-brain barrier during
inflammatory pain. J Cereb Blood Flow Metab. 29:1084–1098. 2009.
View Article : Google Scholar
|
|
18
|
Inumaru J, Nagano O, Takahashi E, Ishimoto
T, Nakamura S, Suzuki Y, Niwa S, Umezawa K, Tanihara H and Saya H:
Molecular mechanisms regulating dissociation of cell-cell junction
of epithelial cells by oxidative stress. Genes Cells. 14:703–716.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Deroanne CF, Hamelryckx D, Ho TT, Lambert
CA, Catroux P, Lapiere CM and Nusgens BV: Cdc42 downregulates MMP-1
expression by inhibiting the ERK1/2 pathway. J Cell Sci.
118:1173–1183. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Dovas A, Choi Y, Yoneda A, Multhaupt HA,
Kwon SH, Kang D, Oh ES and Couchman JR: Serine 34 phosphorylation
of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling
from conventional protein kinase C to RhoGTPase in cell adhesion. J
Biol Chem. 285:23296–23308. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Leung TH, Ching YP, Yam JW, Wong CM, Yau
TO, Jin DY and Ng IO: Deleted in liver cancer 2 (DLC2) suppresses
cell transformation by means of inhibition of RhoA activity. Proc
Natl Acad Sci USA. 102:15207–15212. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Edlund S, Landstrom M, Heldin CH and
Aspenstrom P: Transforming growth factor-beta-induced mobilization
of actin cytoskeleton requires signaling by small GTPases Cdc42 and
RhoA. Mol Biol Cell. 13:902–914. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Lee HT and Kay EP: FGF-2 induced
reorganization and disruption of actin cytoskeleton through PI
3-kinase, Rho, and Cdc42 in corneal endothelial cells. Mol Vision.
9:624–634. 2003.PubMed/NCBI
|
|
24
|
Patel S, Takagi KI, Suzuki J, Imaizumi A,
Kimura T, Mason RM, Kamimura T and Zhang Z: RhoGTPase activation is
a key step in renal epithelial mesenchymal transdifferentiation. J
Am Soc Nephrol. 16:1977–1984. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Ruiz-Loredo AY, Lopez E and Lopez-Colome
AM: Thrombin promotes actin stress fiber formation in RPE through
Rho/ROCK-mediated MLC phosphorylation. J Cell Physiol. 226:414–423.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Lapointe TK, O’Connor PM, Jones NL, Menard
D and Buret AG: Interleukin-1 receptor phosphorylation activates
Rho kinase to disrupt human gastric tight junctional claudin-4
during Helicobacter pylori infection. Cell Microbiol.
12:692–703. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Yin J and Yu FS: Rho kinases regulate
corneal epithelial wound healing. Am J Physiol. 295:C378–C387.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Bruewer M, Hopkins AM, Hobert ME, Nusrat A
and Madara JL: RhoA, Rac1, and Cdc42 exert distinct effects on
epithelial barrier via selective structural and biochemical
modulation of junctional proteins and F-actin. Am J Physiol.
287:C327–C335. 2004. View Article : Google Scholar : PubMed/NCBI
|
