|
1
|
Parkin DM, Bray F, Ferlay J and Pisani P:
Global cancer statistics, 2002. CA Cancer J Clin. 55:74–108. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Williams BA, Sugimura H, Endo C, Nichols
FC, Cassivi SD, Allen MS, Pairolero PC, Deschamps C and Yang P:
Predicting postrecurrence survival among completely resected
non-small-cell lung cancer patients. Ann Thorac Surg. 81:1021–1027.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Okada F: Inflammation-related
carcinogenesis: current findings in epidemiological trends, causes
and mechanisms. Yonago Acta Med. 57:65–72. 2014.PubMed/NCBI
|
|
4
|
Loomis D, Grosse Y, Lauby-Secretan B, El
Ghissassi F, Bouvard V, Benbrahim-Tallaa L, Guha N, Baan R, Mattock
H and Straif K; International Agency for Research on Cancer
Monograph Working Group IARC: The carcinogenicity of outdoor air
pollution. Lancet Oncol. 14:1262–1263. 2013. View Article : Google Scholar
|
|
5
|
Tazawa H, Okada F, Kobayashi T, Tada M,
Mori Y, Une Y, Sendo F, Kobayashi M and Hosokawa M: Infiltration of
neutrophils is required for acquisition of metastatic phenotype of
benign murine fibrosarcoma cells: implication of
inflammation-associated carcinogenesis and tumor progression. Am J
Pathol. 163:2221–2232. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Okada F, Kobayashi M, Tanaka H, Kobayashi
T, Tazawa H, Iuchi Y, Onuma K, Hosokawa M, Dinauer MC and Hunt NH:
The role of nicotinamide adenine dinucleotide phosphate
oxidase-derived reactive oxygen species in the acquisition of
metastatic ability of tumor cells. Am J Pathol. 169:294–302. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Okada F, Tazawa H, Kobayashi T, Kobayashi
M and Hosokawa M: Involvement of reactive nitrogen oxides for
acquisition of metastatic properties of benign tumors in a model of
inflammation-based tumor progression. Nitric Oxide. 14:122–129.
2006. View Article : Google Scholar
|
|
8
|
Kalluri R and Weinberg RA: The basics of
epithelial-mesenchymal transition. J Clin Invest. 119:1420–1428.
2009. View
Article : Google Scholar : PubMed/NCBI
|
|
9
|
Gemmill RM, Roche J, Potiron VA, Nasarre
P, Mitas M, Coldren CD, Helfrich BA, Garrett-Mayer E, Bunn PA and
Drabkin HA: ZEB1-responsive genes in non-small cell lung cancer.
Cancer Lett. 300:66–78. 2011. View Article : Google Scholar
|
|
10
|
Prudkin L, Liu DD, Ozburn NC, Sun M,
Behrens C, Tang X, Brown KC, Bekele BN, Moran C and Wistuba II:
Epithelial-to-mesenchymal transition in the development and
progression of adenocarcinoma and squamous cell carcinoma of the
lung. Mod Pathol. 22:668–678. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Pohlers D, Brenmoehl J, Löffler I, Müller
CK, Leipner C, Schultze-Mosgau S, Stallmach A, Kinne RW and Wolf G:
TGF-β and fibrosis in different organs - molecular pathway
imprints. Biochim Biophys Acta. 1792:746–756. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Kawata M, Koinuma D, Ogami T, Umezawa K,
Iwata C, Watabe T and Miyazono K: TGF-β-induced
epithelial-mesenchymal transition of A549 lung adenocarcinoma cells
is enhanced by pro-inflammatory cytokines derived from RAW 264.7
macrophage cells. J Biochem. 151:205–216. 2012. View Article : Google Scholar
|
|
13
|
Park MK, You HJ, Lee HJ, Kang JH, Oh SH,
Kim SY and Lee CH: Transglutaminase-2 induces N-cadherin expression
in TGF-β1-induced epithelial mesenchymal transition via
c-Jun-N-terminal kinase activation by protein phosphatase 2A
down-regulation. Eur J Cancer. 49:1692–1705. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Kashihara N, Haruna Y, Kondeti VK and
Kanwar YS: Oxidative stress in diabetic nephropathy. Curr Med Chem.
17:4256–4269. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Kobayashi M and Yamamoto M: Molecular
mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene
regulation. Antioxid Redox Signal. 7:385–394. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Ryoo IG, Ha H and Kwak MK: Inhibitory role
of the KEAP1-NRF2 pathway in TGFβ1-stimulated renal epithelial
transition to fibroblastic cells: a modulatory effect on SMAD
signaling. PLoS One. 9:e932652014. View Article : Google Scholar
|
|
17
|
Hamabe A, Konno M, Tanuma N, Shima H,
Tsunekuni K, Kawamoto K, Nishida N, Koseki J, Mimori K, Gotoh N, et
al: Role of pyruvate kinase M2 in transcriptional regulation
leading to epithelial-mesenchymal transition. Proc Natl Acad Sci
USA. 111:15526–15531. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Anastasiou D, Poulogiannis G, Asara JM,
Boxer MB, Jiang JK, Shen M, Bellinger G, Sasaki AT, Locasale JW,
Auld DS, et al: Inhibition of pyruvate kinase M2 by reactive oxygen
species contributes to cellular antioxidant responses. Science.
334:1278–1283. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Fadok VA, Bratton DL, Konowal A, Freed PW,
Westcott JY and Henson PM: Macrophages that have ingested apoptotic
cells in vitro inhibit proinflammatory cytokine production through
autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J
Clin Invest. 101:890–898. 1998. View
Article : Google Scholar : PubMed/NCBI
|
|
20
|
Serhan CN, Hong S, Gronert K, Colgan SP,
Devchand PR, Mirick G and Moussignac RL: Resolvins: a family of
bioactive products of omega-3 fatty acid transformation circuits
initiated by aspirin treatment that counter proinflammation
signals. J Exp Med. 196:1025–1037. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Lee HJ, Park MK, Lee EJ and Lee CH:
Resolvin D1 inhibits TGF-β1-induced epithelial mesenchymal
transition of A549 lung cancer cells via lipoxin A4 receptor/formyl
peptide receptor 2 and GPR32. Int J Biochem Cell Biol.
45:2801–2807. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Steeg PS: Tumor metastasis: mechanistic
insights and clinical challenges. Nat Med. 12:895–904. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Neil JR, Johnson KM, Nemenoff RA and
Schiemann WP: Cox-2 inactivates Smad signaling and enhances EMT
stimulated by TGF-β through a PGE2-dependent mechanisms.
Carcinogenesis. 29:2227–2235. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Talbot LJ, Bhattacharya SD and Kuo PC:
Epithelial-mesenchymal transition, the tumor microenvironment, and
metastatic behavior of epithelial malignancies. Int J Biochem Mol
Biol. 3:117–136. 2012.PubMed/NCBI
|
|
25
|
Yang W and Lu Z: Pyruvate kinase M2 at a
glance. J Cell Sci. 128:1655–1560. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Spite M, Norling LV, Summers L, Yang R,
Cooper D, Petasis NA, Flower RJ, Perretti M and Serhan CN: Resolvin
D2 is a potent regulator of leukocytes and controls microbial
sepsis. Nature. 461:1287–1291. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Wu SH, Zhang YM, Tao HX and Dong L:
Lipoxin A(4) inhibits transition of epithelial to mesenchymal cells
in proximal tubules. Am J Nephrol. 32:122–136. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Homma S, Ishii Y, Morishima Y, Yamadori T,
Matsuno Y, Haraguchi N, Kikuchi N, Satoh H, Sakamoto T, Hizawa N,
et al: Nrf2 enhances cell proliferation and resistance to
anticancer drugs in human lung cancer. Clin Cancer Res.
15:3423–3432. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Brown SL, Sekhar KR, Rachakonda G, Sasi S
and Freeman ML: Activating transcription factor 3 is a novel
repressor of the nuclear factor erythroid-derived 2-related factor
2 (Nrf2)-regulated stress pathway. Cancer Res. 68:364–368. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Dhakshinamoorthy S, Jain AK, Bloom DA and
Jaiswal AK: Bach1 competes with Nrf2 leading to negative regulation
of the antioxidant response element (ARE)-mediated NAD(P) H:quinone
oxidoreductase 1 gene expression and induction in response to
antioxidants. J Biol Chem. 280:16891–16900. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Christofk HR, Vander Heiden MG, Harris MH,
Ramanathan A, Gerszten RE, Wei R, Fleming MD, Schreiber SL and
Cantley LC: The M2 splice isoform of pyruvate kinase is important
for cancer metabolism and tumour growth. Nature. 452:230–233. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Yang W, Xia Y, Cao Y, Zheng Y, Bu W, Zhang
L, You MJ, Koh MY, Cote G, Aldape K, et al: EGFR-induced and PKCε
monoubiquitylation-dependent NF-κB activation upregulates PKM2
expression and promotes tumorigenesis. Mol Cell. 48:771–784. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Majumder PK, Febbo PG, Bikoff R, Berger R,
Xue Q, McMahon LM, Manola J, Brugarolas J, McDonnell TJ, Golub TR,
et al: mTOR inhibition reverses Akt-dependent prostate
intraepithelial neoplasia through regulation of apoptotic and
HIF-1-dependent pathways. Nat Med. 10:594–601. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Sun Q, Chen X, Ma J, Peng H, Wang F, Zha
X, Wang Y, Jing Y, Yang H, Chen R, et al: Mammalian target of
rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is
critical for aerobic glycolysis and tumor growth. Proc Natl Acad
Sci USA. 108:4129–4134. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Iqbal MA and Bamezai RNK: Resveratrol
inhibits cancer cell metabolism by down regulating pyruvate kinase
M2 via inhibition of mammalian target of rapamycin. PLoS One.
7:e367642012. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Hambright HG, Meng P, Kumar AP and Ghosh
R: Inhibition of PI3K/AKT/mTOR axis disrupts oxidative
stress-mediated survival of melanoma cells. Oncotarget.
6:7195–7208. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Al-Zaubai N, Johnstone CN, Leong MM, Li J,
Rizzacasa M and Stewart AG: Resolvin D2 supports MCF-7 cell
proliferation via activation of estrogen receptor. J Pharmacol Exp
Ther. 351:172–180. 2014. View Article : Google Scholar : PubMed/NCBI
|
