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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2016 Volume 38 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

The molecular basis of fertilization (Review)

Katerina Georgadaki, Nikolas Khoury, Demetrios A. Spandidos, Vasilis Zoumpourlis
Pages: 979-986
Published online on: 31 August 2016

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Review

Regulatory effects of GRK2 on GPCRs and non-GPCRs and possible use as a drug target (Review)

Chen-Chen Han, Yang Ma, Yifan Li, Yang Wang, Wei Wei
Pages: 987-994
Published online on: 29 August 2016

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Review

Oxidative stress in the trabecular meshwork (Review)

Jing Zhao, Shuang Wang, Wei Zhong, Ben Yang, Lixia Sun, Yajuan Zheng
Pages: 995-1002
Published online on: 24 August 2016

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Review Open Access

The molecular mechanisms of action of PPAR-γ agonists in the treatment of corneal alkali burns (Review)

Hongyan Zhou, Wensong Zhang, Miaomiao Bi, Jie Wu
Pages: 1003-1011
Published online on: 04 August 2016

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Review Open Access

Occupational and environmental exposure to pesticides and cytokine pathways in chronic diseases (Review)

Silvia Gangemi, Eliza Gofita, Chiara Costa, Michele Teodoro, Giusi Briguglio, Dragana Nikitovic, George Tzanakakis, Aristides M. Tsatsakis, Martin F. Wilks, Demetrios A. Spandidos, Concettina Fenga
Pages: 1012-1020
Published online on: 02 September 2016

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Review

Importance of the interaction between immune cells and tumor vasculature mediated by thalidomide in cancer treatment (Review)

Xin Wang, Yanwei Shen, Shuting Li, Meng Lv, Xiaoman Zhang, Jiao Yang, Fan Wang, Jin Yang
Pages: 1021-1029
Published online on: 31 August 2016

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Review

Sphingosine 1-phosphate in metabolic syndrome (Review)

Wei Chen, Hongwei Lu, Jie Yang, Hong Xiang, Hui Peng
Pages: 1030-1038
Published online on: 07 September 2016

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Article Open Access

Mitochondrial DNA depletion causes decreased ROS production and resistance to apoptosis

Hulin Chen, Junling Wang, Zhongrong Liu, Huilan Yang, Yingjie Zhu, Minling Zhao, Yan Liu, Miaomiao Yan
Pages: 1039-1046
Published online on: 03 August 2016

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Article Open Access

5-Azacytidine suppresses EC9706 cell proliferation and metastasis by upregulating the expression of SOX17 and CDH1

Wenli Li, Dan Wu, Ziyu Niu, Dalei Jiang, Huan Ma, Heming He, Xiangjun Xie, Yuanlong He
Pages: 1047-1054
Published online on: 11 August 2016

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Article Open Access

Hepatocyte growth factor inhibits hypoxia/reoxygenation-induced activation of xanthine oxidase in endothelial cells through the JAK2 signaling pathway

Ying Qian Zhang, Shun Ying Hu, Yun Dai Chen, Ming Zhou Guo, Shan Wang
Pages: 1055-1062
Published online on: 18 August 2016

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Article Open Access

Functional differences between neonatal and adult fibroblasts and keratinocytes: Donor age affects epithelial-mesenchymal crosstalk in vitro

Rosana Mateu, Veronika Živicová, Eliška Drobná Krejčí, Miloš Grim, Hynek Strnad, Čestmír Vlček, Michal Kolář, Lukáš Lacina, Peter Gál, Jiří Borský, Karel Smetana Jr, Barbora Dvořánková
Pages: 1063-1074
Published online on: 11 August 2016

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Article Open Access

Epigallocatechin-3-gallate prevents oxidative stress-induced cellular senescence in human mesenchymal stem cells via Nrf2

Joo-Hyun Shin, Hyo-Jin Jeon, Jihye Park, Mi-Sook Chang
Pages: 1075-1082
Published online on: 01 August 2016

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Article Open Access

Low vitamin D-modulated calcium-regulating proteins in psoriasis vulgaris plaques: S100A7 overexpression depends on joint involvement

Susana Cubillos, Johannes Norgauer
Pages: 1083-1092
Published online on: 26 August 2016

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Article Open Access

Effects of recombinant human adenovirus-p53 on the regression of hepatic fibrosis

Yehong Liu, Puye Yang, Na Chen, Shumei Lin, Min Liu
Pages: 1093-1100
Published online on: 26 August 2016

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Article Open Access

Anti-atherogenic effect of Humulus japonicus in apolipoprotein E-deficient mice

Haian Lim, Jung-Ran Noh, Yong-Hoon Kim, Jung Hwan Hwang, Kyoung-Shim Kim, Dong-Hee Choi, Min-Jeong Go, Sang-Seop Han, Won-Keun Oh, Chul-Ho Lee
Pages: 1101-1110
Published online on: 01 September 2016

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Article Open Access

Targeted next-generation sequencing helps to decipher the genetic and phenotypic heterogeneity of hypertrophic cardiomyopathy

Massimiliano Cecconi, Maria I. Parodi, Francesco Formisano, Paolo Spirito, Camillo Autore, Maria B. Musumeci, Stefano Favale, Cinzia Forleo, Claudio Rapezzi, Elena Biagini, Sabrina Davì, Elisabetta Canepa, Loredana Pennese, Mauro Castagnetta, Dario Degiorgio, Domenico A. Coviello
Pages: 1111-1124
Published online on: 07 September 2016

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Article Open Access

Interleukin-21 promotes osteoclastogenesis in RAW264.7 cells through the PI3K/AKT signaling pathway independently of RANKL

Rui Xing, Yingjian Zhang, Changhong Li, Lin Sun, Lin Yang, Jinxia Zhao, Xiangyuan Liu
Pages: 1125-1134
Published online on: 30 August 2016

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Article Open Access

Metformin-suppressed differentiation of human visceral preadipocytes: Involvement of microRNAs

Koji Fujita, Hisakazu Iwama, Kyoko Oura, Tomoko Tadokoro, Kayo Hirose, Miwako Watanabe, Teppei Sakamoto, Akiko Katsura, Shima Mimura, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Asahiro Morishita, Hirohito Yoneyama, Keiichi Okano, Yasuyuki Suzuki, Takashi Himoto, Tsutomu Masaki
Pages: 1135-1140
Published online on: 02 September 2016

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Article Open Access

Three-dimensional co-culture of mesenchymal stromal cells and differentiated osteoblasts on human bio-derived bone scaffolds supports active multi-lineage hematopoiesis in vitro: Functional implication of the biomimetic HSC niche

Xiaobing Huang, Biao Zhu, Xiaodong Wang, Rong Xiao, Chunsen Wang
Pages: 1141-1151
Published online on: 19 August 2016

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Article Open Access

Neuroprotective effects of sodium hydrosulfide against β-amyloid-induced neurotoxicity

Xiao-Hui Li, Yuan-Yuan Deng, Fei Li, Jing-Shan Shi, Qi-Hai Gong
Pages: 1152-1160
Published online on: 09 August 2016

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Article Open Access

Glucagon-like peptide-1 attenuates advanced oxidation protein product-mediated damage in islet microvascular endothelial cells partly through the RAGE pathway

Zhen Zhang, Lei Yang, Lei Lei, Rongping Chen, Hong Chen, Hua Zhang
Pages: 1161-1169
Published online on: 19 August 2016

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Article Open Access

Identification of hub genes and regulatory factors of glioblastoma multiforme subgroups by RNA-seq data analysis

Yanan Li, Weijie Min, Mengmeng Li, Guosheng Han, Dongwei Dai, Lei Zhang, Xin Chen, Xinglai Wang, Yuhui Zhang, Zhijian Yue, Jianmin Liu
Pages: 1170-1178
Published online on: 26 August 2016

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Article Open Access

Notoginsenoside R1 ameliorates podocyte injury in rats with diabetic nephropathy by activating the PI3K/Akt signaling pathway

Guodong Huang, Jianzhen Lv, Tongyu Li, Guoli Huai, Xiang Li, Shaowei Xiang, Longlong Wang, Zhenlin Qin, Jianli Pang, Bingyu Zou, Yi Wang
Pages: 1179-1189
Published online on: 24 August 2016

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Article Open Access

Pro-apoptotic effects of rHSG on C6 glioma cells

Peng Gao, Yourui Zou, Bing Zhang, Shucai Jiang, Wenjiong Hao, Hui Guo, Guojin Huo, Juncheng Wang, Wei Zhao, Bing Shen
Pages: 1190-1198
Published online on: 31 August 2016

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Article Open Access

Bmi-1 promotes the invasion and migration of colon cancer stem cells through the downregulation of E-cadherin

Zefeng Zhang, Xiaoling Bu, Hao Chen, Qiyi Wang, Weihong Sha
Pages: 1199-1207
Published online on: 07 September 2016

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Article

miR‑221 targets HMGA2 to inhibit bleomycin‑induced pulmonary fibrosis by regulating TGF‑β1/Smad3-induced EMT

Yi‑Chun Wang, Jing‑Shi Liu, Hao‑Ke Tang, Jing Nie, Ji‑Xian Zhu, Ling‑Ling Wen, Qu‑Lian Guo
Pages: 1208-1216
Published online on: 11 August 2016

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Article

p43 induces IP-10 expression through the JAK-STAT signaling pathway in HMEC-1 cells

Wei Wang, Junjie Tan, Yuhua Xing, Naipeng Kan, Jingyi Ling, Guifu Dong, Gang Liu, Huipeng Chen
Pages: 1217-1224
Published online on: 19 August 2016

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Article

Protective effects of miR-25 against hypoxia/reoxygenation‑induced fibrosis and apoptosis of H9c2 cells

Qifang Liu, Yongjin Wang, Tianlun Yang, Wu Wei
Pages: 1225-1234
Published online on: 11 August 2016

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Article

Aspirin-triggered resolvin D1 inhibits TGF-β1-induced EMT through the inhibition of the mTOR pathway by reducing the expression of PKM2 and is closely linked to oxidative stress

Yu Liu, Xiaolong Yuan, Wenhui Li, Qianqian Cao, Yusheng Shu
Pages: 1235-1242
Published online on: 29 August 2016

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Article

Identification of five novel arginine vasopressin gene mutations in patients with familial neurohypophyseal diabetes insipidus

Dan Tian, Jing Cen, Min Nie, Feng Gu
Pages: 1243-1249
Published online on: 11 August 2016

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Article

Wogonin inhibits the proliferation and invasion, and induces the apoptosis of HepG2 and Bel7402 HCC cells through NF‑κB/Bcl-2, EGFR and EGFR downstream ERK/AKT signaling

Xiaodong Liu, Shuo Tian, Mei Liu, Lingyan Jian, Limei Zhao
Pages: 1250-1256
Published online on: 05 August 2016

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Article

Cathepsin D is involved in the oxygen and glucose deprivation/reperfusion-induced apoptosis of astrocytes

Jianlin Liu, Lin Yang, Hongyan Tian, Qiang Ma
Pages: 1257-1263
Published online on: 18 August 2016

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Article

Analgesic effects of 1,2,3,4,6-penta-O-galloyl-β-D-glucose in an animal model of lipopolysaccharide-induced pain

Kun Chun, Si-Oh Kim, Sang-Han Lee
Pages: 1264-1270
Published online on: 01 September 2016

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Article

Naringenin pre-treatment inhibits neuroapoptosis and ameliorates cognitive impairment in rats exposed to isoflurane anesthesia by regulating the PI3/Akt/PTEN signalling pathway and suppressing NF-κB-mediated inflammation

Fu-Zhou Hua, Jun Ying, Jing Zhang, Xi-Feng Wang, Yan-Hui Hu, Ying-Ping Liang, Qin Liu, Guo-Hai Xu
Pages: 1271-1280
Published online on: 25 August 2016

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Article

Anti-obesity effects of boiled tuna extract in mice with obesity induced by a high-fat diet

Youngmin Kim, Mi-Jin Kwon, Jeong-Wook Choi, Min-Kyeong Lee, Chorong Kim, Jaehun Jung, Heny Aprianita, Heesop Nam, Taek-Jeong Nam
Pages: 1281-1288
Published online on: 01 August 2016

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Article

Identification of Mycobacterium tuberculosis in the cerebrospinal fluid of patients with meningitis using nested PCR

Nora Rios-Sarabia, Olivia Hernández-González, Jorge González-Y-Merchand, Guadalupe Gordillo, Guillermo Vázquez-Rosales, Leopoldo Muñoz-Pérez, Javier Torres, Carmen Maldonado-Bernal
Pages: 1289-1295
Published online on: 04 August 2016

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Article

In vitro study comparing the efficacy of the water-soluble HSP90 inhibitors, 17-AEPGA and 17-DMAG, with that of the non‑water-soluble HSP90 inhibitor, 17-AAG, in breast cancer cell lines

Tarik Ghadban, André Jessen, Matthias Reeh, Judith L. Dibbern, Sven Mahner, Volkmar Mueller, Ulrich F. Wellner, Cenap Güngör, Jakob R. Izbicki, Yogesh K. Vashist
Pages: 1296-1302
Published online on: 03 August 2016

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Article

Overexpression of miR-200a protects cardiomyocytes against hypoxia-induced apoptosis by modulating the kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 signaling axis

Xiaoxia Sun, Hong Zuo, Chunmei Liu, Yafeng Yang
Pages: 1303-1311
Published online on: 26 August 2016

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Retraction Open Access

[Retracted] Systemic delivery of synthetic microRNA-451 is an effective therapeutic strategy for the treatment of lung cancer

Baisong Lou, Xin Zhou
Pages: 1312-1312
Published online on: 29 July 2016

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Correction Open Access

[Corrigendum] TLR4-mediated NF-κB signaling pathway mediates HMGB1-induced pancreatic injury in mice with severe acute pancreatitis

Gang Li, Xuejun Wu, Le Yang, Yuxiang He, Yang Liu, Xing Jin, Hai Yuan
Pages: 1313-1313
Published online on: 17 August 2016

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Journal Cover
November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Spatial multi‑omics identifies an SPP1+ macrophage‑driven anti‑apoptotic niche in osteoarthritis synovium via the SPP1‑CD44 axis

Han Gong, Hao Shen, Feng Zhang, Wei Wang, Sheng Zhou, Lei Wang, Yu Sun
Article Number: 334
Published online on: 29 September 2026

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Review Open Access

Novel insights into the role of the renal interstitial microenvironment in Randall's plaque formation (Review)

Jialiang Wang, Zhangcheng Liao, Minghui Liu, Yizhou Wang, Yu Cui, Hequn Chen, Feng Zeng, Zewu Zhu
Article Number: 333
Published online on: 29 September 2026

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Correction Open Access

[Corrigendum] Alteration of the Wnt/GSK3β/β‑catenin signalling pathway by rapamycin ameliorates pathology in an Alzheimer's disease model

Jingfei Chen, Zhimin Long, Yanzhen Li, Min  Luo, Shifang  Luo, Guiqiong He
Article Number: 332
Published online on: 28 September 2026

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Article Open Access

miR‑222‑3p inhibits diabetic skin wound healing by targeting APLN

Ruyan Jie, Ying Tang, Tingting Wu, Chenfan Zhang, Man Song, Xiaotong Zhao, Mingwei Chen
Article Number: 331
Published online on: 25 September 2026

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Correction Open Access

[Corrigendum] Adjudin delays cellular senescence through Sirt3‑mediated attenuation of ROS production

Keyi Geng, Ningzhen Fu, Xiao Yang, Weiliang Xia
Article Number: 330
Published online on: 23 September 2026

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Article Open Access

Salidroside attenuates myocardial ischemia‑reperfusion‑induced oxidative stress and ferroptosis by promoting USP11‑mediated  deubiquitination of PRDX2

Zhi-Cong Qiu, Jian-Nan Li, Yi-Zhou Li, Zi-Ming Wu, Xu-Dong Luo, Rui-Yuan Zeng, Song-Qing Lai, Shi-Tao Zhao, Li Wan
Article Number: 329
Published online on: 23 September 2026

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Review Open Access

Reprogramming of cell death in gastric cancer: From molecular mechanisms to therapeutic potential (Review)

Mengru Liu, Zhujun Wu, Qiao Chen, Weiguo Ni, Ying Chen, Yixin Zhu, Yu Chen, Haifeng Ma, Yan Lin
Article Number: 328
Published online on: 23 September 2026

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Article Open Access

Remimazolam attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis involving the AKT/SLC7A11/GPX4 axis

Xiyuan Chen, Jianghong Zhao, Xingtong He, Yuqi Zhang, Jiao Wu, Chao Jiang, Yi Yang, Ji Xiao
Article Number: 327
Published online on: 22 September 2026

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Review Open Access

Tumor‑immune spatiotemporal co‑evolution: A new paradigm for understanding and overcoming therapy resistance in metastatic castration‑resistant prostate cancer (Review)

Li Yan, Xiaoke Sun, Pengxiao Su
Article Number: 326
Published online on: 21 September 2026

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Review Open Access

Research progress on the role of IL‑37 in gynecological and obstetrics‑related diseases (Review)

Hongjing Wang, Renukha Arjune, Weiyu Gan, Na Guo, Nan Yu, Ting Xiong
Article Number: 325
Published online on: 21 September 2026

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Expression of Concern Open Access

[Expression of Concern] PAT protein mRNA expression in primary rat hepatocytes: Effects of exposure to fatty acids

Elena Grasselli, Adriana Voci, Carlo Pesce, Laura Canesi, Emilia Fugassa, Gabriella Gallo, Laura Vergani
Article Number: 324
Published online on: 21 September 2026

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Review Open Access

Neutrophil extracellular traps in cardiovascular disease: Mechanisms and therapeutic implications (Review)

Zhao Wang, Mingde Chang, Wenyu Shang, Yunfeng Jia, Xiaoyu Shan, Xinnong Chen, Yingxi Yang, Junping Zhang
Article Number: 323
Published online on: 18 September 2026

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Article Open Access

Sirt1 attenuates calcific aortic valve disease by inhibiting ferroptosis and enhancing mitochondrial function via the activation of the Nrf2/HO‑1/FTH1 axis

Fei Yan, Lei Shi, Yuechan Wang, Ying Zhao, Yuanyuan Wu, Dubiao Xian, Yunheng Liang, Ning Wang, Hongwang Cui, Minni Zhang
Article Number: 322
Published online on: 18 September 2026

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Article Open Access

Ketogenic diet attenuates Müller cell activation and retinal neuroinflammation in autoimmune glaucoma through acetylation‑mediated FOXO signalling

Sisi Tan, Xiaochen Wang, Yunfan Zheng, Zhenni Mou, Lihong Zeng, Jingchang Yuan, Xiao Fan, Miao Wei, Yujia Huo, Ruotong Ouyang, Yanyu Pu, Junqin Lei, Xi Gao, Dangdang Wang, Yang Peng, Hong Li
Article Number: 321
Published online on: 17 September 2026

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Review Open Access

ILC3s as central regulators of mucosal homeostasis and disease pathogenesis (Review)

Jingwen Zhang, Lili Bao, Jiaxi Li, Xia Li, Lu Qiao, Jiaxian Cui, Xiaoxia He, Mingyu Zhang, Jingkun Lu, Xuan Zhang, Jing Dong, Gesi Tao, Yaoqing Feng, Yun Peng Tian, Pengwei Zhao, Ya Tuo
Article Number: 320
Published online on: 17 September 2026

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Review Open Access

Small extracellular vesicles in osteoarthritis: A double‑edged sword regulating inflammation and cartilage homeostasis (Review)

Yifan Yang, Jiachen Liang, Xiangyu Shi, Anqi Niu, Ruifang Gao, Xiuping Wu, Xiaojuan Guo, Xiaotong Shi, Kejie Cao, Bing Li, Ran Li
Article Number: 319
Published online on: 17 September 2026

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Review Open Access

Exosomal circular RNAs in the tumor immune microenvironment: From regulatory mechanisms to therapeutic opportunities and translational hurdles (Review)

Wenlong Zhang, Nuo Chen, Liya Gong, Yu Dong, Hui Shen, Xin Liu, Jie Sun, Luxuan Liu, Zhe Jin, Liaoyuan Wang, Xue Han, Bin Zhang, Shuixing Zhang
Article Number: 318
Published online on: 17 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ginsenoside Rg1 protects against H2O2‑induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro

Tan-Zhen Xu, Xiao-Yan Shen, Ling-Ling Sun, Ya-Li Chen, Bi-Qiong Zhang, Da-Ke Huang, Wei-Zu Li
Article Number: 317
Published online on: 16 September 2026

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Review Open Access

tRNA‑derived RNAs in hepatic diseases: From biological functions to clinical translation (Review)

Yaotian Cai, Yifei Chen, Fuji Yang, Yongmin Yan, Ting Jiang
Article Number: 316
Published online on: 15 September 2026

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Review Open Access

Monocytes in pneumonia: Functional plasticity and innate memory (Review) 

Run-Ze Li, Zhi-Han Xie, Li Chen, Yun-Xiao Shang, Fei Wang, Wan-Jie Huang, Qi Cheng
Article Number: 315
Published online on: 15 September 2026

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Correction Open Access

[Corrigendum] Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis

Hao Lin, Xinran Cheng, Yangyang Ren, Yongmei Zhang, Weixu Chen, Qingyan Lu, Yiqing Tian
Article Number: 314
Published online on: 14 September 2026

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Review Open Access

Ferroptosis in heatstroke: Mechanisms and therapeutic perspectives (Review)

Hongguang Gao, Yang Chen, Tianshan Zhang, Yujun Shi, Rong Yao
Article Number: 313
Published online on: 10 September 2026

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Correction Open Access

[Corrigendum] Inactivation of von Hippel‑Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR‑210/VMP1 signaling pathway

Ting Liu, Le Zhao, Wei Chen, Zhen Li, Huilian Hou, Lu Ding, Xu Li
Article Number: 312
Published online on: 10 September 2026

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Review Open Access

Interferon regulatory factors orchestrate CD8+ T cell function (Review)

Fa-Xi Wang, Chun-Liang Yang, Shan-Jie Rong, Qi-Jie Chen, Xiong-Tao Yue, Fei Sun
Article Number: 311
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Rapamycin‑induced miR‑30a downregulation inhibits senescence of VSMCs by targeting Beclin1

Pan Tan, Haiqin Wang, Junkun Zhan, Xinyu Ma, Xingjun Cui, Yanjiao Wang, Yi Wang, Jiayu Zhong, Youshuo Liu
Article Number: 310
Published online on: 07 September 2026

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Review Open Access

Deciphering the function and mechanism of extracorporeal shock wave therapy in knee osteoarthritis (Review)

Yixuan Chen, Siqi Song, Yuchen Zhu, Shiqi Wang, Jieyuan Hu, Chenxu Liu, Yuchen Cai, Yushi Hu
Article Number: 309
Published online on: 04 September 2026

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Review Open Access

Multi‑omics integration in osteoarthritis: Unraveling cell‑type‑specific gene‑metabolite networks for precision medicine (Review)

Ying Yang, Ruichen Zheng, Yun Zhang, Dongmei Ye, Jiale Xie, Changliang Zhu
Article Number: 308
Published online on: 03 September 2026

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Review Open Access

Autophagy determines the fate of immune cells by regulating metabolic remodeling and PANoptosis (Review)

Yanan Guo, Xinyue Zhou, Yixiao Tian, Dan Chen, Xiaofeng Xie, Bin Zhou, Yingxia Tian, Yaqing Zhang
Article Number: 307
Published online on: 03 September 2026

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Review Open Access

Programmed cell death in metabolic syndrome: From molecular mechanisms to therapeutic strategies (Review)

Jialin Zhong, Maofu Zhang, Yafang Zheng, Cuicui Gong, Yasheng Deng, Lisha Sun, Dongqi Zhou, Qian Zhou, Qiu Chen
Article Number: 306
Published online on: 03 September 2026

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Review Open Access

Research progress on lysine acetylation (Review)

Minghui Zhang, Yuqi Zhang, Haoxin Yin, Junyuan Yan, Yingling Dong, Xin Zhao, Tianyi Cui, Bin Lv, Xiumei Gao
Article Number: 305
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Human ether‑à‑go‑go‑related gene mutation L539fs/47‑hERG leads to cell apoptosis through the endoplasmic reticulum stress pathway

Shuting Ma, Yun Zhao, Miaomiao Cao, Chaofeng Sun
Article Number: 304
Published online on: 02 September 2026

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Review Open Access

Targeting integrated cell death networks in sepsis‑associated acute kidney injury: Shared regulatory nodes and diet‑related small molecule modulation (Review)

Lin Song, Aifeng He, Wei Jiang, Keran Shi, Jing Wang, Lu Xu, Jiangquan Yu, Ruiqiang Zheng
Article Number: 303
Published online on: 31 August 2026

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Article Open Access

Effect of MALT1 inhibition by MI‑2 on the microglial phenotype switch, inflammatory cytokine secretion, neuronal loss and oxidative stress in Alzheimer's disease

Yuanlong Li, Hua Fan, Xiong Han, Ming Ni, Xiaodan Hou, Hailan Xia, Yinzhu Shi, Lin Zhang, Jun Sun
Article Number: 302
Published online on: 31 August 2026

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Review Open Access

Salvianolic acid monomers against metastasis: Decoding the multilayered interception of EMT, angiogenesis and immune evasion (Review)

Shiting Jiang, Dan Liu, Tingting Wei, Qiwei Shi, Haowen Wang, Yidan Gao, Pingsu Mao, Wenli Yang
Article Number: 301
Published online on: 31 August 2026

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Retraction Open Access

[Retracted] Silencing of decoy receptor 3 (DcR3) expression by siRNA in pancreatic carcinoma cells induces Fas ligand‑mediated apoptosis in vitro and in vivo

Jian Zhou, Shiduo Song, Songbin He, Zhenxin Wang, Bing Zhang, Dechun Li, Dongming Zhu
Article Number: 300
Published online on: 31 August 2026

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Review Open Access

Research progress on BTG2 in non‑tumor diseases (Review)

Shuling Li, Xiaomei Liu, Zheng Zhang, Ling Yang, Yuxuan Li, Qiongdan Hu
Article Number: 299
Published online on: 28 August 2026

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Review Open Access

Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Review Open Access

Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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December-2026 Volume 58 Issue 6

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Anesthetics and cancer biology: Translational evidence from perioperative modulation to drug repurposing (Review)

Ting Yang, Jiao Tang, Muhammad Saqib Mudabbar, Huan Hu, Qiang Fu, Chunlan Pu
Article Number: 336
Published online on: 05 October 2026

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Expression of Concern Open Access

[Expression of Concern] Multiple roles of SOCS proteins: Differential expression of SOCS1 and SOCS3 in atherosclerosis

Xiao Liang, Ming He, Tao Chen, Yan Liu, Yu-Ling Tian, Yu-Liang Wu, Yan Zhao, Yan Shen, Zu-Yi Yuan
Article Number: 335
Published online on: 30 September 2026

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