Journal Articles
Review
The molecular basis of fertilization (Review)
Katerina Georgadaki, Nikolas Khoury, Demetrios A. Spandidos, Vasilis Zoumpourlis
Pages: 979-986 Published online on: 31 August 2016
Review
Regulatory effects of GRK2 on GPCRs and non-GPCRs and possible use as a drug target (Review)
Chen-Chen Han, Yang Ma, Yifan Li, Yang Wang, Wei Wei
Pages: 987-994 Published online on: 29 August 2016
Review
Oxidative stress in the trabecular meshwork (Review)
Jing Zhao, Shuang Wang, Wei Zhong, Ben Yang, Lixia Sun, Yajuan Zheng
Pages: 995-1002 Published online on: 24 August 2016
Review
The molecular mechanisms of action of PPAR-γ agonists in the treatment of corneal alkali burns (Review)
Hongyan Zhou, Wensong Zhang, Miaomiao Bi, Jie Wu
Pages: 1003-1011 Published online on: 04 August 2016
Review
Occupational and environmental exposure to pesticides and cytokine pathways in chronic diseases (Review)
Silvia Gangemi, Eliza Gofita, Chiara Costa, Michele Teodoro, Giusi Briguglio, Dragana Nikitovic, George Tzanakakis, Aristides M. Tsatsakis, Martin F. Wilks, Demetrios A. Spandidos, Concettina Fenga
Pages: 1012-1020 Published online on: 02 September 2016
Review
Importance of the interaction between immune cells and tumor vasculature mediated by thalidomide in cancer treatment (Review)
Xin Wang, Yanwei Shen, Shuting Li, Meng Lv, Xiaoman Zhang, Jiao Yang, Fan Wang, Jin Yang
Pages: 1021-1029 Published online on: 31 August 2016
Review
Sphingosine 1-phosphate in metabolic syndrome (Review)
Wei Chen, Hongwei Lu, Jie Yang, Hong Xiang, Hui Peng
Pages: 1030-1038 Published online on: 07 September 2016
Article
Mitochondrial DNA depletion causes decreased ROS production and resistance to apoptosis
Hulin Chen, Junling Wang, Zhongrong Liu, Huilan Yang, Yingjie Zhu, Minling Zhao, Yan Liu, Miaomiao Yan
Pages: 1039-1046 Published online on: 03 August 2016
Article
5-Azacytidine suppresses EC9706 cell proliferation and metastasis by upregulating the expression of SOX17 and CDH1
Wenli Li, Dan Wu, Ziyu Niu, Dalei Jiang, Huan Ma, Heming He, Xiangjun Xie, Yuanlong He
Pages: 1047-1054 Published online on: 11 August 2016
Article
Hepatocyte growth factor inhibits hypoxia/reoxygenation-induced activation of xanthine oxidase in endothelial cells through the JAK2 signaling pathway
Ying Qian Zhang, Shun Ying Hu, Yun Dai Chen, Ming Zhou Guo, Shan Wang
Pages: 1055-1062 Published online on: 18 August 2016
Article
Functional differences between neonatal and adult fibroblasts and keratinocytes: Donor age affects epithelial-mesenchymal crosstalk in vitro
Rosana Mateu, Veronika Živicová, Eliška Drobná Krejčí, Miloš Grim, Hynek Strnad, Čestmír Vlček, Michal Kolář, Lukáš Lacina, Peter Gál, Jiří Borský, Karel Smetana Jr, Barbora Dvořánková
Pages: 1063-1074 Published online on: 11 August 2016
Article
Epigallocatechin-3-gallate prevents oxidative stress-induced cellular senescence in human mesenchymal stem cells via Nrf2
Joo-Hyun Shin, Hyo-Jin Jeon, Jihye Park, Mi-Sook Chang
Pages: 1075-1082 Published online on: 01 August 2016
Article
Low vitamin D-modulated calcium-regulating proteins in psoriasis vulgaris plaques: S100A7 overexpression depends on joint involvement
Susana Cubillos, Johannes Norgauer
Pages: 1083-1092 Published online on: 26 August 2016
Article
Effects of recombinant human adenovirus-p53 on the regression of hepatic fibrosis
Yehong Liu, Puye Yang, Na Chen, Shumei Lin, Min Liu
Pages: 1093-1100 Published online on: 26 August 2016
Article
Anti-atherogenic effect of Humulus japonicus in apolipoprotein E-deficient mice
Haian Lim, Jung-Ran Noh, Yong-Hoon Kim, Jung Hwan Hwang, Kyoung-Shim Kim, Dong-Hee Choi, Min-Jeong Go, Sang-Seop Han, Won-Keun Oh, Chul-Ho Lee
Pages: 1101-1110 Published online on: 01 September 2016
Article
Targeted next-generation sequencing helps to decipher the genetic and phenotypic heterogeneity of hypertrophic cardiomyopathy
Massimiliano Cecconi, Maria I. Parodi, Francesco Formisano, Paolo Spirito, Camillo Autore, Maria B. Musumeci, Stefano Favale, Cinzia Forleo, Claudio Rapezzi, Elena Biagini, Sabrina Davì, Elisabetta Canepa, Loredana Pennese, Mauro Castagnetta, Dario Degiorgio, Domenico A. Coviello
Pages: 1111-1124 Published online on: 07 September 2016
Article
Interleukin-21 promotes osteoclastogenesis in RAW264.7 cells through the PI3K/AKT signaling pathway independently of RANKL
Rui Xing, Yingjian Zhang, Changhong Li, Lin Sun, Lin Yang, Jinxia Zhao, Xiangyuan Liu
Pages: 1125-1134 Published online on: 30 August 2016
Article
Metformin-suppressed differentiation of human visceral preadipocytes: Involvement of microRNAs
Koji Fujita, Hisakazu Iwama, Kyoko Oura, Tomoko Tadokoro, Kayo Hirose, Miwako Watanabe, Teppei Sakamoto, Akiko Katsura, Shima Mimura, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Asahiro Morishita, Hirohito Yoneyama, Keiichi Okano, Yasuyuki Suzuki, Takashi Himoto, Tsutomu Masaki
Pages: 1135-1140 Published online on: 02 September 2016
Article
Three-dimensional co-culture of mesenchymal stromal cells and differentiated osteoblasts on human bio-derived bone scaffolds supports active multi-lineage hematopoiesis in vitro: Functional implication of the biomimetic HSC niche
Xiaobing Huang, Biao Zhu, Xiaodong Wang, Rong Xiao, Chunsen Wang
Pages: 1141-1151 Published online on: 19 August 2016
Article
Neuroprotective effects of sodium hydrosulfide against β-amyloid-induced neurotoxicity
Xiao-Hui Li, Yuan-Yuan Deng, Fei Li, Jing-Shan Shi, Qi-Hai Gong
Pages: 1152-1160 Published online on: 09 August 2016
Article
Glucagon-like peptide-1 attenuates advanced oxidation protein product-mediated damage in islet microvascular endothelial cells partly through the RAGE pathway
Zhen Zhang, Lei Yang, Lei Lei, Rongping Chen, Hong Chen, Hua Zhang
Pages: 1161-1169 Published online on: 19 August 2016
Article
Identification of hub genes and regulatory factors of glioblastoma multiforme subgroups by RNA-seq data analysis
Yanan Li, Weijie Min, Mengmeng Li, Guosheng Han, Dongwei Dai, Lei Zhang, Xin Chen, Xinglai Wang, Yuhui Zhang, Zhijian Yue, Jianmin Liu
Pages: 1170-1178 Published online on: 26 August 2016
Article
Notoginsenoside R1 ameliorates podocyte injury in rats with diabetic nephropathy by activating the PI3K/Akt signaling pathway
Guodong Huang, Jianzhen Lv, Tongyu Li, Guoli Huai, Xiang Li, Shaowei Xiang, Longlong Wang, Zhenlin Qin, Jianli Pang, Bingyu Zou, Yi Wang
Pages: 1179-1189 Published online on: 24 August 2016
Article
Pro-apoptotic effects of rHSG on C6 glioma cells
Peng Gao, Yourui Zou, Bing Zhang, Shucai Jiang, Wenjiong Hao, Hui Guo, Guojin Huo, Juncheng Wang, Wei Zhao, Bing Shen
Pages: 1190-1198 Published online on: 31 August 2016
Article
Bmi-1 promotes the invasion and migration of colon cancer stem cells through the downregulation of E-cadherin
Zefeng Zhang, Xiaoling Bu, Hao Chen, Qiyi Wang, Weihong Sha
Pages: 1199-1207 Published online on: 07 September 2016
Article
miR‑221 targets HMGA2 to inhibit bleomycin‑induced pulmonary fibrosis by regulating TGF‑β1/Smad3-induced EMT
Yi‑Chun Wang, Jing‑Shi Liu, Hao‑Ke Tang, Jing Nie, Ji‑Xian Zhu, Ling‑Ling Wen, Qu‑Lian Guo
Pages: 1208-1216 Published online on: 11 August 2016
Article
p43 induces IP-10 expression through the JAK-STAT signaling pathway in HMEC-1 cells
Wei Wang, Junjie Tan, Yuhua Xing, Naipeng Kan, Jingyi Ling, Guifu Dong, Gang Liu, Huipeng Chen
Pages: 1217-1224 Published online on: 19 August 2016
Article
Protective effects of miR-25 against hypoxia/reoxygenation‑induced fibrosis and apoptosis of H9c2 cells
Qifang Liu, Yongjin Wang, Tianlun Yang, Wu Wei
Pages: 1225-1234 Published online on: 11 August 2016
Article
Aspirin-triggered resolvin D1 inhibits TGF-β1-induced EMT through the inhibition of the mTOR pathway by reducing the expression of PKM2 and is closely linked to oxidative stress
Yu Liu, Xiaolong Yuan, Wenhui Li, Qianqian Cao, Yusheng Shu
Pages: 1235-1242 Published online on: 29 August 2016
Article
Identification of five novel arginine vasopressin gene mutations in patients with familial neurohypophyseal diabetes insipidus
Dan Tian, Jing Cen, Min Nie, Feng Gu
Pages: 1243-1249 Published online on: 11 August 2016
Article
Wogonin inhibits the proliferation and invasion, and induces the apoptosis of HepG2 and Bel7402 HCC cells through NF‑κB/Bcl-2, EGFR and EGFR downstream ERK/AKT signaling
Xiaodong Liu, Shuo Tian, Mei Liu, Lingyan Jian, Limei Zhao
Pages: 1250-1256 Published online on: 05 August 2016
Article
Cathepsin D is involved in the oxygen and glucose deprivation/reperfusion-induced apoptosis of astrocytes
Jianlin Liu, Lin Yang, Hongyan Tian, Qiang Ma
Pages: 1257-1263 Published online on: 18 August 2016
Article
Analgesic effects of 1,2,3,4,6-penta-O-galloyl-β-D-glucose in an animal model of lipopolysaccharide-induced pain
Kun Chun, Si-Oh Kim, Sang-Han Lee
Pages: 1264-1270 Published online on: 01 September 2016
Article
Naringenin pre-treatment inhibits neuroapoptosis and ameliorates cognitive impairment in rats exposed to isoflurane anesthesia by regulating the PI3/Akt/PTEN signalling pathway and suppressing NF-κB-mediated inflammation
Fu-Zhou Hua, Jun Ying, Jing Zhang, Xi-Feng Wang, Yan-Hui Hu, Ying-Ping Liang, Qin Liu, Guo-Hai Xu
Pages: 1271-1280 Published online on: 25 August 2016
Article
Anti-obesity effects of boiled tuna extract in mice with obesity induced by a high-fat diet
Youngmin Kim, Mi-Jin Kwon, Jeong-Wook Choi, Min-Kyeong Lee, Chorong Kim, Jaehun Jung, Heny Aprianita, Heesop Nam, Taek-Jeong Nam
Pages: 1281-1288 Published online on: 01 August 2016
Article
Identification of Mycobacterium tuberculosis in the cerebrospinal fluid of patients with meningitis using nested PCR
Nora Rios-Sarabia, Olivia Hernández-González, Jorge González-Y-Merchand, Guadalupe Gordillo, Guillermo Vázquez-Rosales, Leopoldo Muñoz-Pérez, Javier Torres, Carmen Maldonado-Bernal
Pages: 1289-1295 Published online on: 04 August 2016
Article
In vitro study comparing the efficacy of the water-soluble HSP90 inhibitors, 17-AEPGA and 17-DMAG, with that of the non‑water-soluble HSP90 inhibitor, 17-AAG, in breast cancer cell lines
Tarik Ghadban, André Jessen, Matthias Reeh, Judith L. Dibbern, Sven Mahner, Volkmar Mueller, Ulrich F. Wellner, Cenap Güngör, Jakob R. Izbicki, Yogesh K. Vashist
Pages: 1296-1302 Published online on: 03 August 2016
Article
Overexpression of miR-200a protects cardiomyocytes against hypoxia-induced apoptosis by modulating the kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 signaling axis
Xiaoxia Sun, Hong Zuo, Chunmei Liu, Yafeng Yang
Pages: 1303-1311 Published online on: 26 August 2016
Retraction
[Retracted] Systemic delivery of synthetic microRNA-451 is an effective therapeutic strategy for the treatment of lung cancer
Baisong Lou, Xin Zhou
Pages: 1312-1312 Published online on: 29 July 2016
Correction