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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2016 Volume 38 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

The molecular basis of fertilization (Review)

Katerina Georgadaki, Nikolas Khoury, Demetrios A. Spandidos, Vasilis Zoumpourlis
Pages: 979-986
Published online on: 31 August 2016

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Review

Regulatory effects of GRK2 on GPCRs and non-GPCRs and possible use as a drug target (Review)

Chen-Chen Han, Yang Ma, Yifan Li, Yang Wang, Wei Wei
Pages: 987-994
Published online on: 29 August 2016

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Review

Oxidative stress in the trabecular meshwork (Review)

Jing Zhao, Shuang Wang, Wei Zhong, Ben Yang, Lixia Sun, Yajuan Zheng
Pages: 995-1002
Published online on: 24 August 2016

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Review Open Access

The molecular mechanisms of action of PPAR-γ agonists in the treatment of corneal alkali burns (Review)

Hongyan Zhou, Wensong Zhang, Miaomiao Bi, Jie Wu
Pages: 1003-1011
Published online on: 04 August 2016

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Review Open Access

Occupational and environmental exposure to pesticides and cytokine pathways in chronic diseases (Review)

Silvia Gangemi, Eliza Gofita, Chiara Costa, Michele Teodoro, Giusi Briguglio, Dragana Nikitovic, George Tzanakakis, Aristides M. Tsatsakis, Martin F. Wilks, Demetrios A. Spandidos, Concettina Fenga
Pages: 1012-1020
Published online on: 02 September 2016

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Review

Importance of the interaction between immune cells and tumor vasculature mediated by thalidomide in cancer treatment (Review)

Xin Wang, Yanwei Shen, Shuting Li, Meng Lv, Xiaoman Zhang, Jiao Yang, Fan Wang, Jin Yang
Pages: 1021-1029
Published online on: 31 August 2016

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Review

Sphingosine 1-phosphate in metabolic syndrome (Review)

Wei Chen, Hongwei Lu, Jie Yang, Hong Xiang, Hui Peng
Pages: 1030-1038
Published online on: 07 September 2016

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Article Open Access

Mitochondrial DNA depletion causes decreased ROS production and resistance to apoptosis

Hulin Chen, Junling Wang, Zhongrong Liu, Huilan Yang, Yingjie Zhu, Minling Zhao, Yan Liu, Miaomiao Yan
Pages: 1039-1046
Published online on: 03 August 2016

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Article Open Access

5-Azacytidine suppresses EC9706 cell proliferation and metastasis by upregulating the expression of SOX17 and CDH1

Wenli Li, Dan Wu, Ziyu Niu, Dalei Jiang, Huan Ma, Heming He, Xiangjun Xie, Yuanlong He
Pages: 1047-1054
Published online on: 11 August 2016

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Article Open Access

Hepatocyte growth factor inhibits hypoxia/reoxygenation-induced activation of xanthine oxidase in endothelial cells through the JAK2 signaling pathway

Ying Qian Zhang, Shun Ying Hu, Yun Dai Chen, Ming Zhou Guo, Shan Wang
Pages: 1055-1062
Published online on: 18 August 2016

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Article Open Access

Functional differences between neonatal and adult fibroblasts and keratinocytes: Donor age affects epithelial-mesenchymal crosstalk in vitro

Rosana Mateu, Veronika Živicová, Eliška Drobná Krejčí, Miloš Grim, Hynek Strnad, Čestmír Vlček, Michal Kolář, Lukáš Lacina, Peter Gál, Jiří Borský, Karel Smetana Jr, Barbora Dvořánková
Pages: 1063-1074
Published online on: 11 August 2016

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Article Open Access

Epigallocatechin-3-gallate prevents oxidative stress-induced cellular senescence in human mesenchymal stem cells via Nrf2

Joo-Hyun Shin, Hyo-Jin Jeon, Jihye Park, Mi-Sook Chang
Pages: 1075-1082
Published online on: 01 August 2016

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Article Open Access

Low vitamin D-modulated calcium-regulating proteins in psoriasis vulgaris plaques: S100A7 overexpression depends on joint involvement

Susana Cubillos, Johannes Norgauer
Pages: 1083-1092
Published online on: 26 August 2016

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Article Open Access

Effects of recombinant human adenovirus-p53 on the regression of hepatic fibrosis

Yehong Liu, Puye Yang, Na Chen, Shumei Lin, Min Liu
Pages: 1093-1100
Published online on: 26 August 2016

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Article Open Access

Anti-atherogenic effect of Humulus japonicus in apolipoprotein E-deficient mice

Haian Lim, Jung-Ran Noh, Yong-Hoon Kim, Jung Hwan Hwang, Kyoung-Shim Kim, Dong-Hee Choi, Min-Jeong Go, Sang-Seop Han, Won-Keun Oh, Chul-Ho Lee
Pages: 1101-1110
Published online on: 01 September 2016

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Article Open Access

Targeted next-generation sequencing helps to decipher the genetic and phenotypic heterogeneity of hypertrophic cardiomyopathy

Massimiliano Cecconi, Maria I. Parodi, Francesco Formisano, Paolo Spirito, Camillo Autore, Maria B. Musumeci, Stefano Favale, Cinzia Forleo, Claudio Rapezzi, Elena Biagini, Sabrina Davì, Elisabetta Canepa, Loredana Pennese, Mauro Castagnetta, Dario Degiorgio, Domenico A. Coviello
Pages: 1111-1124
Published online on: 07 September 2016

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Article Open Access

Interleukin-21 promotes osteoclastogenesis in RAW264.7 cells through the PI3K/AKT signaling pathway independently of RANKL

Rui Xing, Yingjian Zhang, Changhong Li, Lin Sun, Lin Yang, Jinxia Zhao, Xiangyuan Liu
Pages: 1125-1134
Published online on: 30 August 2016

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Article Open Access

Metformin-suppressed differentiation of human visceral preadipocytes: Involvement of microRNAs

Koji Fujita, Hisakazu Iwama, Kyoko Oura, Tomoko Tadokoro, Kayo Hirose, Miwako Watanabe, Teppei Sakamoto, Akiko Katsura, Shima Mimura, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Asahiro Morishita, Hirohito Yoneyama, Keiichi Okano, Yasuyuki Suzuki, Takashi Himoto, Tsutomu Masaki
Pages: 1135-1140
Published online on: 02 September 2016

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Article Open Access

Three-dimensional co-culture of mesenchymal stromal cells and differentiated osteoblasts on human bio-derived bone scaffolds supports active multi-lineage hematopoiesis in vitro: Functional implication of the biomimetic HSC niche

Xiaobing Huang, Biao Zhu, Xiaodong Wang, Rong Xiao, Chunsen Wang
Pages: 1141-1151
Published online on: 19 August 2016

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Article Open Access

Neuroprotective effects of sodium hydrosulfide against β-amyloid-induced neurotoxicity

Xiao-Hui Li, Yuan-Yuan Deng, Fei Li, Jing-Shan Shi, Qi-Hai Gong
Pages: 1152-1160
Published online on: 09 August 2016

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Article Open Access

Glucagon-like peptide-1 attenuates advanced oxidation protein product-mediated damage in islet microvascular endothelial cells partly through the RAGE pathway

Zhen Zhang, Lei Yang, Lei Lei, Rongping Chen, Hong Chen, Hua Zhang
Pages: 1161-1169
Published online on: 19 August 2016

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Article Open Access

Identification of hub genes and regulatory factors of glioblastoma multiforme subgroups by RNA-seq data analysis

Yanan Li, Weijie Min, Mengmeng Li, Guosheng Han, Dongwei Dai, Lei Zhang, Xin Chen, Xinglai Wang, Yuhui Zhang, Zhijian Yue, Jianmin Liu
Pages: 1170-1178
Published online on: 26 August 2016

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Article Open Access

Notoginsenoside R1 ameliorates podocyte injury in rats with diabetic nephropathy by activating the PI3K/Akt signaling pathway

Guodong Huang, Jianzhen Lv, Tongyu Li, Guoli Huai, Xiang Li, Shaowei Xiang, Longlong Wang, Zhenlin Qin, Jianli Pang, Bingyu Zou, Yi Wang
Pages: 1179-1189
Published online on: 24 August 2016

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Article Open Access

Pro-apoptotic effects of rHSG on C6 glioma cells

Peng Gao, Yourui Zou, Bing Zhang, Shucai Jiang, Wenjiong Hao, Hui Guo, Guojin Huo, Juncheng Wang, Wei Zhao, Bing Shen
Pages: 1190-1198
Published online on: 31 August 2016

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Article Open Access

Bmi-1 promotes the invasion and migration of colon cancer stem cells through the downregulation of E-cadherin

Zefeng Zhang, Xiaoling Bu, Hao Chen, Qiyi Wang, Weihong Sha
Pages: 1199-1207
Published online on: 07 September 2016

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Article

miR‑221 targets HMGA2 to inhibit bleomycin‑induced pulmonary fibrosis by regulating TGF‑β1/Smad3-induced EMT

Yi‑Chun Wang, Jing‑Shi Liu, Hao‑Ke Tang, Jing Nie, Ji‑Xian Zhu, Ling‑Ling Wen, Qu‑Lian Guo
Pages: 1208-1216
Published online on: 11 August 2016

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Article

p43 induces IP-10 expression through the JAK-STAT signaling pathway in HMEC-1 cells

Wei Wang, Junjie Tan, Yuhua Xing, Naipeng Kan, Jingyi Ling, Guifu Dong, Gang Liu, Huipeng Chen
Pages: 1217-1224
Published online on: 19 August 2016

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Article

Protective effects of miR-25 against hypoxia/reoxygenation‑induced fibrosis and apoptosis of H9c2 cells

Qifang Liu, Yongjin Wang, Tianlun Yang, Wu Wei
Pages: 1225-1234
Published online on: 11 August 2016

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Article

Aspirin-triggered resolvin D1 inhibits TGF-β1-induced EMT through the inhibition of the mTOR pathway by reducing the expression of PKM2 and is closely linked to oxidative stress

Yu Liu, Xiaolong Yuan, Wenhui Li, Qianqian Cao, Yusheng Shu
Pages: 1235-1242
Published online on: 29 August 2016

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Article

Identification of five novel arginine vasopressin gene mutations in patients with familial neurohypophyseal diabetes insipidus

Dan Tian, Jing Cen, Min Nie, Feng Gu
Pages: 1243-1249
Published online on: 11 August 2016

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Article

Wogonin inhibits the proliferation and invasion, and induces the apoptosis of HepG2 and Bel7402 HCC cells through NF‑κB/Bcl-2, EGFR and EGFR downstream ERK/AKT signaling

Xiaodong Liu, Shuo Tian, Mei Liu, Lingyan Jian, Limei Zhao
Pages: 1250-1256
Published online on: 05 August 2016

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Article

Cathepsin D is involved in the oxygen and glucose deprivation/reperfusion-induced apoptosis of astrocytes

Jianlin Liu, Lin Yang, Hongyan Tian, Qiang Ma
Pages: 1257-1263
Published online on: 18 August 2016

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Article

Analgesic effects of 1,2,3,4,6-penta-O-galloyl-β-D-glucose in an animal model of lipopolysaccharide-induced pain

Kun Chun, Si-Oh Kim, Sang-Han Lee
Pages: 1264-1270
Published online on: 01 September 2016

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Article

Naringenin pre-treatment inhibits neuroapoptosis and ameliorates cognitive impairment in rats exposed to isoflurane anesthesia by regulating the PI3/Akt/PTEN signalling pathway and suppressing NF-κB-mediated inflammation

Fu-Zhou Hua, Jun Ying, Jing Zhang, Xi-Feng Wang, Yan-Hui Hu, Ying-Ping Liang, Qin Liu, Guo-Hai Xu
Pages: 1271-1280
Published online on: 25 August 2016

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Article

Anti-obesity effects of boiled tuna extract in mice with obesity induced by a high-fat diet

Youngmin Kim, Mi-Jin Kwon, Jeong-Wook Choi, Min-Kyeong Lee, Chorong Kim, Jaehun Jung, Heny Aprianita, Heesop Nam, Taek-Jeong Nam
Pages: 1281-1288
Published online on: 01 August 2016

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Article

Identification of Mycobacterium tuberculosis in the cerebrospinal fluid of patients with meningitis using nested PCR

Nora Rios-Sarabia, Olivia Hernández-González, Jorge González-Y-Merchand, Guadalupe Gordillo, Guillermo Vázquez-Rosales, Leopoldo Muñoz-Pérez, Javier Torres, Carmen Maldonado-Bernal
Pages: 1289-1295
Published online on: 04 August 2016

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Article

In vitro study comparing the efficacy of the water-soluble HSP90 inhibitors, 17-AEPGA and 17-DMAG, with that of the non‑water-soluble HSP90 inhibitor, 17-AAG, in breast cancer cell lines

Tarik Ghadban, André Jessen, Matthias Reeh, Judith L. Dibbern, Sven Mahner, Volkmar Mueller, Ulrich F. Wellner, Cenap Güngör, Jakob R. Izbicki, Yogesh K. Vashist
Pages: 1296-1302
Published online on: 03 August 2016

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Article

Overexpression of miR-200a protects cardiomyocytes against hypoxia-induced apoptosis by modulating the kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 signaling axis

Xiaoxia Sun, Hong Zuo, Chunmei Liu, Yafeng Yang
Pages: 1303-1311
Published online on: 26 August 2016

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Retraction Open Access

[Retracted] Systemic delivery of synthetic microRNA-451 is an effective therapeutic strategy for the treatment of lung cancer

Baisong Lou, Xin Zhou
Pages: 1312-1312
Published online on: 29 July 2016

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Correction Open Access

[Corrigendum] TLR4-mediated NF-κB signaling pathway mediates HMGB1-induced pancreatic injury in mice with severe acute pancreatitis

Gang Li, Xuejun Wu, Le Yang, Yuxiang He, Yang Liu, Xing Jin, Hai Yuan
Pages: 1313-1313
Published online on: 17 August 2016

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

DUSP26: Unveiling a critical molecular mediator and therapeutic target in developmental dysplasia of the hip‑associated secondary osteoarthritis

Enbo Wang, Haixiang Zhang, Dechao Wu, Sadik Ali, Xianglu Ji
Article Number: 105
Published online on: 26 February 2026

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Review Open Access

mTOR signaling pathway in primary Sjögren's syndrome: Pathogenesis and potential therapeutic targets (Review)

Rongxiu Huo, Yanting Yang, Chengcheng Wei, Yang Yang, Danli Meng, Jinying Lin, Xinxiang Huang
Article Number: 104
Published online on: 25 February 2026

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Article Open Access

Bumetanide‑blocked SLC12A2 exerts a protective effect in experimental diabetic retinopathy

Yuting Zhang, Xiuli Wang, Qinyue Xie, Yue Huang, Dongjia Huang, Ziqing Liu, Tong Xu, Man Ni, Hongwei Yang
Article Number: 103
Published online on: 25 February 2026

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Article Open Access

Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 102
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] A novel role for Livin in the response to ultraviolet B radiation and pterygium development

Shuang-Qing Wu, Qi-Bin Xu, Wen-Yan Sheng, Lin-Ya Su, Li-Wei Zhu
Article Number: 101
Published online on: 24 February 2026

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Article Open Access

Endothelial UNC5B regulates blood‑retinal barrier homeostasis

Yujia Yao, Suyu Wang, Jiajun Li, Qianzi Jin, Ziyi Chen, Qin Jiang, Keran Li
Article Number: 100
Published online on: 20 February 2026

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Review Open Access

Metabolic hubs in reproduction: The regulatory network of lipid droplets in gamete and embryo physiology (Review)

Liuzhu Pan, Zongzhuang Wen, Yi Jin
Article Number: 99
Published online on: 17 February 2026

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Review Open Access

The role and mechanism of IL‑35 in myasthenia gravis (Review)

Jing Mao, Lin-Ming Zhang, Yan-Lin Zhu, Shu-Ji Gao, Ming-Wei Liu
Article Number: 98
Published online on: 17 February 2026

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Article Open Access

miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways

Jing Wang, Yujia Zou, Yani Wang, Zheming Yang, Daoshen Liu, Xiaolin Su, Haixu Song, Kai Xu, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 97
Published online on: 16 February 2026

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Dysregulated post‑translational modifications in granulosa cells drive ovarian dysfunction and potential infertility applications (Review)

Yufei Zhong, Yunfei Zou, Zhuoyuan Yang, Junjun Wang, Zezheng Pan, Jiugeng Feng
Article Number: 96
Published online on: 16 February 2026

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Review Open Access

Microglia‑mediated neuroinflammation in intracerebral hemorrhage: Pathological mechanisms and implications for therapeutic development (Review)

Xuehui Fan, Changzhi Pu, Luyi Zhong, Oucheng Wang, Binyi Zhao, Dongyi Liao, Xue Bai, Guiquan Chen, Guoqiang Yang
Article Number: 95
Published online on: 16 February 2026

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Correction Open Access

[Corrigendum] Silencing of Rac1 modifies lung cancer cell migration, invasion and actin cytoskeleton rearrangements and enhances chemosensitivity to antitumor drugs

Qing-Yong Chen, Li-Qun Xu, De-Min Jiao, Qing-Hua Yao, Yan-Yi Wang, Hui-Zhen Hu, Yu-Quan Wu, Jia Song, Jie Yan, Li-Jun Wu
Article Number: 94
Published online on: 12 February 2026

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Article Open Access

Orcinol glucoside ameliorates pulmonary fibrosis by suppressing hyaluronic acid synthesis and macrophage M2 polarization via targeting hyaluronic acid synthase 2

Caizi Li, Xinglinzi Tang, Xiaoru Luo, Xin Lai, Jing Yang, Zheng Xu, Gulizeba Muhetaer, Yizi Xie, Xiufang Huang, Hang Li
Article Number: 93
Published online on: 10 February 2026

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Review Open Access

Helicobacter pylori and hyperglycemia fuel gastric cancer glycolysis: Mechanisms and targeted intervention (Review)

Youjia Liu, Fang Wang, Ya Deng, Yanxia Hu, Feihong Shu, Jie Yu, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Qian Du, Jingyu Xu, Rui Xie
Article Number: 92
Published online on: 09 February 2026

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Targeting the gut‑bone axis through exercise: A novel approach to osteoporosis prevention and treatment (Review)

Jingjing Wu, Siqi Zhang, Junjie Wu, Yuhang Luan, Xingchen Yao, Boyan Xu, Yiting Wang, Yingyue Sheng, Yuzheng Xue, Yilin Ren
Article Number: 91
Published online on: 09 February 2026

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Review Open Access

Chorus line in oral squamous cell carcinoma: How stromal and immune players orchestrate tumor progression (Review)

Eliano Cascardi, Mario Della Mura, Nicoletta Sgarro, Silvia Minei, Gerardo Cazzato, Eugenio Maiorano, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Fábio França Vieira E Silva, Eleonora Lo Muzio, Mario Dioguardi, Andrea Ballini
Article Number: 90
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] Hsa_circularRNA_0079201 suppresses chondrocyte proliferation and endochondral ossification by regulating the microRNA‑140‑3p/SMAD2 signaling pathway in idiopathic short stature 

Xijuan Liu, Chen Yan, Xueqiang Deng, Jingyu Jia
Article Number: 89
Published online on: 09 February 2026

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Review Open Access

Post‑translational modifications in diabetic kidney disease (Review)

Mengfei He, Zihang Wang, Zhuang Miao, Yu Zhao, Lingling Wei, Lijie Zhang, Ruili Yin, Yan Wang, Longyan Yang
Article Number: 88
Published online on: 09 February 2026

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Review Open Access

Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Review Open Access

Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Review Open Access

Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Review Open Access

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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Review Open Access

IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

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