|
1
|
Greider CW and Blackburn EH:
Identification of a specific telomere terminal transferase activity
in Tetrahymena extracts. Cell. 43:405–413. 1985. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
de Lange T: Shelterin: The protein complex
that shapes and safeguards human telomeres. Genes Dev.
19:2100–2110. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Shay JW, Zou Y, Hiyama E and Wright WE:
Telomerase and cancer. Hum Mol Genet. 10:677–685. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Bodnar AG, Ouellette M, Frolkis M, Holt
SE, Chiu CP, Morin GB, Harley CB, Shay JW, Lichtsteiner S and
Wright WE: Extension of life-span by introduction of telomerase
into normal human cells. Science. 279:349–352. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Nakayama J, Tahara H, Tahara E, Saito M,
Ito K, Nakamura H, Nakanishi T, Tahara E, Ide T and Ishikawa F:
Telomerase activation by hTRT in human normal fibroblasts and
hepatocellular carcinomas. Nat Genet. 18:65–68. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Palm W and de Lange T: How shelterin
protects mammalian telomeres. Annu Rev Genet. 42:301–334. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Azzalin CM, Reichenbach P, Khoriauli L,
Giulotto E and Lingner J: Telomeric repeat containing RNA and RNA
surveillance factors at mammalian chromosome ends. Science.
318:798–801. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Schoeftner S and Blasco MA:
Developmentally regulated transcription of mammalian telomeres by
DNA-dependent RNA polymerase II. Nat Cell Biol. 10:228–236. 2008.
View Article : Google Scholar
|
|
9
|
Luke B, Panza A, Redon S, Iglesias N, Li Z
and Lingner J: The Rat1p 5′ to 3′ exonuclease degrades telomeric
repeat-containing RNA and promotes telomere elongation in
Saccharomyces cerevisiae. Mol Cell. 32:465–477. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Vrbsky J, Akimcheva S, Watson JM, Turner
TL, Daxinger L, Vyskot B, Aufsatz W and Riha K: siRNA-mediated
methylation of Arabidopsis telomeres. PLoS Genet. 6:e10009862010.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Bah A, Wischnewski H, Shchepachev V and
Azzalin CM: The telomeric transcriptome of Schizosaccharomyces
pombe. Nucleic Acids Res. 40:2995–3005. 2012. View Article : Google Scholar :
|
|
12
|
Nergadze SG, Farnung BO, Wischnewski H,
Khoriauli L, Vitelli V, Chawla R, Giulotto E and Azzalin CM:
CpG-island promoters drive transcription of human telomeres. RNA.
15:2186–2194. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Arnoult N, Van Beneden A and Decottignies
A: Telomere length regulates TERRA levels through increased
trimethylation of telomeric H3K9 and HP1α. Nat Struct Mol Biol.
19:948–956. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Porro A, Feuerhahn S, Reichenbach P and
Lingner J: Molecular dissection of telomeric repeat-containing RNA
biogenesis unveils the presence of distinct and multiple regulatory
pathways. Mol Cell Biol. 30:4808–4817. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Deng Z, Wang Z, Xiang C, Molczan A, Baubet
V, Conejo-Garcia J, Xu X, Lieberman PM and Dahmane N: Formation of
telomeric repeat-containing RNA (TERRA) foci in highly
proliferating mouse cerebellar neuronal progenitors and
medulloblastoma. J Cell Sci. 125:4383–4394. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Azzalin CM and Lingner J: Telomere
functions grounding on TERRA firma. Trends Cell Biol. 25:29–36.
2015. View Article : Google Scholar
|
|
17
|
Yehezkel S, Segev Y, Viegas-Péquignot E,
Skorecki K and Selig S: Hypomethylation of subtelomeric regions in
ICF syndrome is associated with abnormally short telomeres and
enhanced transcription from telomeric regions. Hum Mol Genet.
17:2776–2789. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Pfeiffer V and Lingner J: TERRA promotes
telomere shortening through exonuclease 1-mediated resection of
chromosome ends. PLoS Genet. 8:e10027472012. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Redon S, Reichenbach P and Lingner J: The
non-coding RNA TERRA is a natural ligand and direct inhibitor of
human telomerase. Nucleic Acids Res. 38:5797–5806. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Iglesias N, Redon S, Pfeiffer V, Dees M,
Lingner J and Luke B: Subtelomeric repetitive elements determine
TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast. EMBO
Rep. 12:587–593. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Farnung BO, Brun CM, Arora R, Lorenzi LE
and Azzalin CM: Telomerase efficiently elongates highly
transcribing telomeres in human cancer cells. PLoS One.
7:e357142012. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Smirnova A, Gamba R, Khoriauli L, Vitelli
V, Nergadze SG and Giulotto E: TERRA expression levels do not
correlate with telomere length and radiation sensitivity in human
cancer cell lines. Front Oncol. 3:1152013. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Van Beneden A, Arnoult N and Decottignies
A: Telomeric RNA expression: Length matters. Front Oncol.
3:1782013. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Deng Z, Wang Z, Stong N, Plasschaert R,
Moczan A, Chen HS, Hu S, Wikramasinghe P, Davuluri RV, Bartolomei
MS, et al: A role for CTCF and cohesin in subtelomere chromatin
organization, TERRA transcription, and telomere end protection.
EMBO J. 31:4165–4178. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Riethman HC, Xiang Z, Paul S, Morse E, Hu
XL, Flint J, Chi HC, Grady DL and Moyzis RK: Integration of
telomere sequences with the draft human genome sequence. Nature.
409:948–951. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
26
|
Riethman H, Ambrosini A, Castaneda C,
Finklestein J, Hu XL, Mudunuri U, Paul S and Wei J: Mapping and
initial analysis of human subtelomeric sequence assemblies. Genome
Res. 14:18–28. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Ambrosini A, Paul S, Hu S and Riethman H:
Human subtelomeric duplicon structure and organization. Genome
Biol. 8:R1512007. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Ro-Choi TS, Raj NB, Pike LM and Busch H:
Effects of alpha-amanitin, cycloheximide, and thioacetamide on low
molecular weight nuclear RNA. Biochemistry. 15:3823–3828. 1976.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Noonberg SB, Scott GK and Benz CC:
Evidence of post-transcriptional regulation of U6 small nuclear
RNA. J Biol Chem. 271:10477–10481. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Vitelli V, Falvo P, Khoriauli L, Smirnova
A, Gamba R, Santagostino M, Nergadze SG and Giulotto E: More on the
lack of correlation between terra expression and telomere length.
Front Oncol. 3:2452013. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Zhou XZ and Lu KP: The
Pin2/TRF1-interacting protein PinX1 is a potent telomerase
inhibitor. Cell. 107:347–359. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Autexier C and Lue NF: The structure and
function of telomerase reverse transcriptase. Annu Rev Biochem.
75:493–517. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Porro A, Feuerhahn S, Delafontaine J,
Riethman H, Rougemont J and Lingner J: Functional characterization
of the TERRA transcriptome at damaged telomeres. Nat Commun.
5:53792014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Scheibe M, Arnoult N, Kappei D, Buchholz
F, Decottignies A, Butter F and Mann M: Quantitative interaction
screen of telomeric repeat-containing RNA reveals novel TERRA
regulators. Genome Res. 23:2149–2157. 2013. View Article : Google Scholar : PubMed/NCBI
|
